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ArticlesPeer ReviewedFull Text
COL7A1 Editing via CRISPR/Cas9 in Recessive Dystrophic Epidermolysis Bullosa
Author / Creator:Hainzl, Stefan ; Peking, Patricia ; Kocher, Thomas ; Murauer, Eva M. ; Larcher, Fernando ; Del Rio, Marcela ; Duarte, Blanca ; Steiner, Markus ; Klausegger, Alfred ; Bauer, Johann W. ; Reichelt, Julia ; Koller, Ulrich
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2017-11, Vol.25 (11), p.2573-2584
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Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study
Author / Creator:Guenou, Hind, PhD ; Nissan, Xavier ; Larcher, Fernando, PhD ; Feteira, Jessica ; Lemaitre, Gilles, PhD ; Saidani, Manoubia ; Del Rio, Marcela, PhD ; Barrault, Christine C ; Bernard, François-Xavier, PhD ; Peschanski, Marc, MD ; Baldeschi, Christine, Dr ; Waksman, Gilles, Prof
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2009-11, Vol.374 (9703), p.1745-1753
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In vitro and In vivo Wound Healing-Promoting Activities of Human Cathelicidin LL-37
Author / Creator:Carretero, Marta ; Escámez, María J. ; García, Marta ; Duarte, Blanca ; Holguín, Almudena ; Retamosa, Luisa ; Jorcano, Jose L. ; Río, Marcela del ; Larcher, Fernando
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2008-01, Vol.128 (1), p.223-236
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Identification of novel small molecule-based strategies of COL7A1 upregulation and readthrough activity for the treatment of recessive dystrophic epidermolysis bullosa
Author / Creator:Jover, Irene ; Ramos, Maria C. ; Escámez, María José ; Lozoya, Estrella ; Tormo, José R. ; de Prado-Verdún, Diana ; Mencía, Ángeles ; Pont, Mercè ; Puig, Carles ; Larraufie, Marie-Helene ; Gutiérrez-Caballero, Cristina ; Reyes, Fernando ; Trincado, Juan Luis ; García-González, Vicente ; Cerrato, Rosario ; Andrés, Miriam ; Crespo, Maribel ; Vicente, Francisca ; Godessart, Nuria ; Genilloud, Olga ; Larcher, Fernando ; Nueda, Arsenio
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-08, Vol.14 (1), p.18969-21, Article 18969
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Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells
Author / Creator:Mencía, Ángeles ; Chamorro, Cristina ; Bonafont, Jose ; Duarte, Blanca ; Holguin, Almudena ; Illera, Nuria ; Llames, Sara G. ; Escámez, Maria José ; Hausser, Ingrid ; Del Río, Marcela ; Larcher, Fernando ; Murillas, Rodolfo
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2018-06, Vol.11 (C), p.68-78
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Targeted Gene Addition in Human Epithelial Stem Cells by Zinc-finger Nuclease-mediated Homologous Recombination
Author / Creator:Coluccio, Andrea ; Miselli, Francesca ; Lombardo, Angelo ; Marconi, Alessandra ; Malagoli Tagliazucchi, Guidantonio ; Gonçalves, Manuel A ; Pincelli, Carlo ; Maruggi, Giulietta ; Del Rio, Marcela ; Naldini, Luigi ; Larcher, Fernando ; Mavilio, Fulvio ; Recchia, Alessandra
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2013-09, Vol.21 (9), p.1695-1704
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Gene Editing for the Efficient Correction of a Recurrent COL7A1 Mutation in Recessive Dystrophic Epidermolysis Bullosa Keratinocytes
Author / Creator:Chamorro, Cristina ; Mencía, Angeles ; Almarza, David ; Duarte, Blanca ; Büning, Hildegard ; Sallach, Jessica ; Hausser, Ingrid ; Del Río, Marcela ; Larcher, Fernando ; Murillas, Rodolfo
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2016-04, Vol.5 (4), p.e307, Article e307
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Early, Non-Invasive Sensing of Sustained Hyperglycemia in Mice Using Millimeter-Wave Spectroscopy
Author / Creator:Moreno-Oyervides, Aldo ; Martín-Mateos, Pedro ; Aguilera-Morillo, M. Carmen ; Ulisse, Giacomo ; Arriba, María C. ; Durban, María ; Del Rio, Marcela ; Larcher, Fernando ; Krozer, Viktor ; Acedo, Pablo
Publisher:Switzerland: MDPI AG
Journal title:Sensors (Basel, Switzerland), 2019-07, Vol.19 (15), p.3347
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Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range
Author / Creator:Dornuf, Fabian ; Martín-Mateos, Pedro ; Duarte, Blanca ; Hils, Bernhard ; Bonilla-Manrique, Oscar Elias ; Larcher, Fernando ; Acedo, Pablo ; Krozer, Viktor
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-07, Vol.7 (1), p.5822-8, Article 5822
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Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy
Author / Creator:Gostyński, Antoni ; Llames, Sara ; García, Marta ; Escamez, María J. ; Martinez-Santamaria, Lucía ; Nijenhuis, Miranda ; Meana, Alvaro ; Pas, Hendri H. ; Larcher, Fernando ; Pasmooij, Anna M.G. ; Jonkman, Marcel F. ; Del Rio, Marcela
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2014-02, Vol.134 (2), p.571-574
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A Humanized Mouse Model of HPV-Associated Pathology Driven by E7 Expression
Author / Creator:Buitrago-Pérez, Águeda ; Hachimi, Mariam ; Dueñas, Marta ; Lloveras, Belén ; Santos, Almudena ; Holguín, Almudena ; Duarte, Blanca ; Santiago, Juan Luis ; Akgül, Baki ; Rodríguez-Peralto, José L. ; Storey, Alan ; Ribas, Catalina ; Larcher, Fernando ; Rio, Marcela del ; Paramio, Jesús M. ; García-Escudero, Ramón
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-07, Vol.7 (7), p.e41743
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Long-term Engraftment of Single Genetically Modified Human Epidermal Holoclones Enables Safety Pre-assessment of Cutaneous Gene Therapy
Author / Creator:Larcher, Fernando ; Dellambra, Elena ; Rico, Laura ; Bondanza, Sergio ; Murillas, Rodolfo ; Cattoglio, Claudia ; Mavilio, Fulvio ; Jorcano, José L ; Zambruno, Giovanna ; Del Rio, Marcela
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2007-09, Vol.15 (9), p.1670-1676
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An In Vivo Model of Wound Healing in Genetically Modified Skin-Humanized Mice
Author / Creator:Escámez, María José ; García, Marta ; Larcher, Fernando ; Meana, Alvaro ; Muñoz, Evangelina ; Jorcano, Jose Luis ; Del Río, Marcela
Publisher:Danvers, MA: Elsevier Inc
Journal title:Journal of investigative dermatology, 2004-12, Vol.123 (6), p.1182-1191
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Functional roles of Akt signaling in mouse skin tumorigenesis
Author / Creator:Segrelles, Carmen ; Ruiz, Sergio ; Perez, Paloma ; Murga, Cristina ; Santos, Mirentxu ; Budunova, Irina V ; Martínez, Jesús ; Larcher, Fernando ; Slaga, Thomas J ; Gutkind, J Silvio ; Jorcano, Jose L ; Paramio, Jesús M
Publisher:Basingstoke: Nature Publishing
Journal title:Oncogene, 2002-01, Vol.21 (1), p.53-64
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VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development
Author / Creator:Larcher, Fernando ; Murillas, Rodolfo ; Bolontrade, Marcela ; Conti, Claudio J ; Jorcano, José L
Publisher:Basingstoke: Nature Publishing
Journal title:Oncogene, 1998-07, Vol.17 (3), p.303-311
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Feeder Layer Cell Actions and Applications
Author / Creator:Llames, Sara ; García-Pérez, Eva ; Meana, Álvaro ; Larcher, Fernando ; del Río, Marcela
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Tissue engineering. Part B, Reviews, 2015-08, Vol.21 (4), p.345-353
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Estela E. Medrano (1943–2010)
Author / Creator:Larcher, Fernando
Publisher:London: Elsevier Inc
Journal title:Journal of investigative dermatology, 2011-04, Vol.131 (4), p.811-811
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Non-viral delivery of CRISPR–Cas9 complexes for targeted gene editing via a polymer delivery system
Author / Creator:O’Keeffe Ahern, Jonathan ; Lara-Sáez, Irene ; Zhou, Dezhong ; Murillas, Rodolfo ; Bonafont, Jose ; Mencía, Ángeles ; García, Marta ; Manzanares, Darío ; Lynch, Jennifer ; Foley, Ruth ; Xu, Qian ; Sigen, A ; Larcher, Fernando ; Wang, Wenxin
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2022-04, Vol.29 (3-4), p.157-170
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Humanization of Tumor Stroma by Tissue Engineering as a Tool to Improve Squamous Cell Carcinoma Xenograft
Author / Creator:Guerrero-Aspizua, Sara ; González-Masa, Andrea ; Conti, Claudio J. ; García, Marta ; Chacón-Solano, Esteban ; Larcher, Fernando ; del Río, Marcela
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2020-03, Vol.21 (6), p.1951
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In-vivo, non-invasive detection of hyperglycemic states in animal models using mm-wave spectroscopy
Author / Creator:Martín-Mateos, Pedro ; Dornuf, Fabian ; Duarte, Blanca ; Hils, Bernhard ; Moreno-Oyervides, Aldo ; Bonilla-Manrique, Oscar Elias ; Larcher, Fernando ; Krozer, Viktor ; Acedo, Pablo
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-09, Vol.6 (1), p.34035, Article 34035
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Showing 1 to 20 of 42 results

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COL7A1 Editing via CRISPR/Cas9 in Recessive Dystrophic Epidermolysis Bullosa

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Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study

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In vitro and In vivo Wound Healing-Promoting Activities of Human Cathelicidin LL-37

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Identification of novel small molecule-based strategies of COL7A1 upregulation and readthrough activity for the treatment of recessive dystrophic epidermolysis bullosa

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Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells

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Targeted Gene Addition in Human Epithelial Stem Cells by Zinc-finger Nuclease-mediated Homologous Recombination

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Gene Editing for the Efficient Correction of a Recurrent COL7A1 Mutation in Recessive Dystrophic Epidermolysis Bullosa Keratinocytes

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Early, Non-Invasive Sensing of Sustained Hyperglycemia in Mice Using Millimeter-Wave Spectroscopy

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Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range

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Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy

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A Humanized Mouse Model of HPV-Associated Pathology Driven by E7 Expression

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Long-term Engraftment of Single Genetically Modified Human Epidermal Holoclones Enables Safety Pre-assessment of Cutaneous Gene Therapy

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An In Vivo Model of Wound Healing in Genetically Modified Skin-Humanized Mice

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Functional roles of Akt signaling in mouse skin tumorigenesis

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VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development

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Feeder Layer Cell Actions and Applications

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Estela E. Medrano (1943–2010)

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Non-viral delivery of CRISPR–Cas9 complexes for targeted gene editing via a polymer delivery system

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Humanization of Tumor Stroma by Tissue Engineering as a Tool to Improve Squamous Cell Carcinoma Xenograft

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In-vivo, non-invasive detection of hyperglycemic states in animal models using mm-wave spectroscopy

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