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ArticlesPeer ReviewedFull Text
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression
Author / Creator:Cheung, Phyllis F. ; Yang, JiaJin ; Fang, Rui ; Borgers, Arianna ; Krengel, Kirsten ; Stoffel, Anne ; Althoff, Kristina ; Yip, Chi Wai ; Siu, Elaine H. L. ; Ng, Linda W. C. ; Lang, Karl S. ; Cham, Lamin B. ; Engel, Daniel R. ; Soun, Camille ; Cima, Igor ; Scheffler, Björn ; Striefler, Jana K. ; Sinn, Marianne ; Bahra, Marcus ; Pelzer, Uwe ; Oettle, Helmut ; Markus, Peter ; Smeets, Esther M. M. ; Aarntzen, Erik H. J. G. ; Savvatakis, Konstantinos ; Liffers, Sven-Thorsten ; Lueong, Smiths S. ; Neander, Christian ; Bazarna, Anna ; Zhang, Xin ; Paschen, Annette ; Crawford, Howard C. ; Chan, Anthony W. H. ; Cheung, Siu Tim ; Siveke, Jens T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-01, Vol.13 (1), p.156-156, Article 156
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Persister state-directed transitioning and vulnerability in melanoma
Author / Creator:Chauvistré, Heike ; Shannan, Batool ; Daignault-Mill, Sheena M. ; Ju, Robert J. ; Picard, Daniel ; Egetemaier, Stefanie ; Váraljai, Renáta ; Gibhardt, Christine S. ; Sechi, Antonio ; Kaschani, Farnusch ; Keminer, Oliver ; Stehbens, Samantha J. ; Liu, Qin ; Yin, Xiangfan ; Jeyakumar, Kirujan ; Vogel, Felix C. E. ; Krepler, Clemens ; Rebecca, Vito W. ; Kubat, Linda ; Lueong, Smiths S. ; Forster, Jan ; Horn, Susanne ; Remke, Marc ; Ehrmann, Michael ; Paschen, Annette ; Becker, Jürgen C. ; Helfrich, Iris ; Rauh, Daniel ; Kaiser, Markus ; Gul, Sheraz ; Herlyn, Meenhard ; Bogeski, Ivan ; Rodríguez-López, José Neptuno ; Haass, Nikolas K. ; Schadendorf, Dirk ; Roesch, Alexander
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-06, Vol.13 (1), p.3055-3055, Article 3055
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SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis
Author / Creator:Njouendou, Abdel Jelil ; Szarvas, Tibor ; Tiofack, Arnol Auvaker Zebaze ; Kenfack, Rovaldo Nguims ; Tonouo, Pamela Derliche ; Ananga, Sidonie Noa ; Bell, Esther H. M. Dina ; Simo, Gustave ; Hoheisel, Jörg D. ; Siveke, Jens T. ; Lueong, Smiths S.
Publisher:England: BioMed Central
Journal title:Molecular cancer, 2023-03, Vol.22 (1), p.52-52, Article 52
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Minimally invasive determination of pancreatic ductal adenocarcinoma (PDAC) subtype by means of circulating cell‐free RNA
Author / Creator:Metzenmacher, Martin ; Zaun, Gregor ; Trajkovic‐Arsic, Marija ; Cheung, Phyllis ; Reissig, Timm M. ; Schürmann, Hendrik ; Neuhoff, Nils ; O'Kane, Grainne ; Ramotar, Stephanie ; Dodd, Anna ; Gallinger, Steven ; Muckenhuber, Alexander ; Knox, Jennifer J. ; Kunzmann, Volker ; Horn, Peter A. ; Hoheisel, Jörg D. ; Siveke, Jens T. ; Lueong, Smiths S.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2025-02, Vol.19 (2), p.357-376
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Plasma Next Generation Sequencing and Droplet Digital-qPCR-Based Quantification of Circulating Cell-Free RNA for Noninvasive Early Detection of Cancer
Author / Creator:Metzenmacher, Martin ; Váraljai, Renáta ; Hegedüs, Balazs ; Cima, Igor ; Forster, Jan ; Schramm, Alexander ; Scheffler, Björn ; Horn, Peter A. ; Klein, Christoph A. ; Szarvas, Tibor ; Reis, Hennig ; Bielefeld, Nicola ; Roesch, Alexander ; Aigner, Clemens ; Kunzmann, Volker ; Wiesweg, Marcel ; Siveke, Jens T. ; Schuler, Martin ; Lueong, Smiths S.
Publisher:Switzerland: MDPI
Journal title:Cancers, 2020-02, Vol.12 (2), p.353
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Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotype
Author / Creator:Albrecht, Lea Jessica ; Höwner, Anna ; Griewank, Klaus ; Lueong, Smiths S. ; Neuhoff, Nils ; Horn, Peter A. ; Sucker, Antje ; Paschen, Annette ; Livingstone, Elisabeth ; Ugurel, Selma ; Zimmer, Lisa ; Horn, Susanne ; Siveke, Jens T. ; Schadendorf, Dirk ; Váraljai, Renáta ; Roesch, Alexander
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational medicine, 2022-11, Vol.12 (11), p.e1090-n/a
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TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer
Author / Creator:Zhao, Ben ; Dierichs, Laura ; Gu, Jiang-Ning ; Trajkovic-Arsic, Marija ; Axel Hilger, Ralf ; Savvatakis, Konstantinos ; Vega-Rubin-de-Celis, Silvia ; Liffers, Sven-Thorsten ; Peña-Llopis, Samuel ; Behrens, Diana ; Hahn, Stephan ; Siveke, Jens T. ; Lueong, Smiths S.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2020-03, Vol.6 (1), p.12-12, Article 12
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ArticlesPeer ReviewedFull Text
BCL-B Promotes Lung Cancer Invasiveness by Direct Inhibition of BOK
Author / Creator:Ramesh, Palaniappan ; Al Kadi, Amal R ; Borse, Gaurav M ; Webendörfer, Maximilian ; Zaun, Gregor ; Metzenmacher, Martin ; Doerr, Fabian ; Bölükbas, Servet ; Hegedüs, Balazs ; Lueong, Smiths S ; Magne, Joelle ; Liu, Beiyun ; Nunez, Greisly ; Schuler, Martin ; Green, Douglas R ; Kalkavan, Halime
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2025-02, Vol.14 (4), p.246
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The clinical utility of cfRNA for disease detection and surveillance: A proof of concept study in non‐small cell lung cancer
Author / Creator:Metzenmacher, Martin ; Hegedüs, Balazs ; Forster, Jan ; Schramm, Alexander ; Horn, Peter A. ; Klein, Christoph A. ; Bielefeld, Nicola ; Ploenes, Till ; Aigner, Clemens ; Siveke, Jens T. ; Schuler, Martin ; Lueong, Smiths S.
Publisher:Melbourne: John Wiley & Sons Australia, Ltd
Journal title:Thoracic cancer, 2022-08, Vol.13 (15), p.2180-2191
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ArticlesPeer ReviewedFull Text
Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma
Author / Creator:Heid, Irina ; Münch, Corinna ; Karakaya, Sinan ; Lueong, Smiths S. ; Winkelkotte, Alina M. ; Liffers, Sven T. ; Godfrey, Laura ; Cheung, Phyllis F. Y. ; Savvatakis, Konstantinos ; Topping, Geoffrey J. ; Englert, Florian ; Kritzner, Lukas ; Grashei, Martin ; Tannapfel, Andrea ; Viebahn, Richard ; Wolters, Heiner ; Uhl, Waldemar ; Vangala, Deepak ; Smeets, Esther M. M. ; Aarntzen, Erik H. J. G. ; Rauh, Daniel ; Weichert, Wilko ; Hoheisel, Jörg D. ; Hahn, Stephan A. ; Schilling, Franz ; Braren, Rickmer ; Trajkovic-Arsic, Marija ; Siveke, Jens T.
Publisher:England: BioMed Central Ltd
Journal title:Cancer & metabolism, 2022-12, Vol.10 (1), p.24-24, Article 24
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Serial Circulating Tumor DNA Mutational Status in Patients with KRAS -Mutant Metastatic Colorectal Cancer from the Phase 3 AIO KRK0207 Trial
Author / Creator:Lueong, Smiths S ; Herbst, Andreas ; Liffers, Sven-Thorsten ; Bielefeld, Nicola ; Horn, Peter A ; Tannapfel, Andrea ; Reinacher-Schick, Anke ; Hinke, Axel ; Hegewisch-Becker, Susanna ; Kolligs, Frank T ; Siveke, Jens T
Publisher:England: American Association for Clinical Chemistry, Inc
Journal title:Clinical chemistry (Baltimore, Md.), 2020-12, Vol.66 (12), p.1510-1520
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ArticlesPeer ReviewedFull Text
Molecular characterization of early breast cancer onset to understand disease phenotypes in African patients
Author / Creator:Tonouo, Pamela Derliche ; Dina Bell, Esther ; Tiofack Zebaze, Arnol Auvaker ; Ndounga, Eliane ; Noa Ananga, Sidonie ; Atenguena, Etienne ; Simo, Gustave ; Njouendou, Abdel Jelil ; Lueong, Smiths S.
Publisher:New York: Springer US
Journal title:Medical oncology (Northwood, London, England), 2022-11, Vol.40 (1), p.13-13, Article 13
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ArticlesPeer ReviewedFull Text
Personalised proteome analysis by means of protein microarrays made from individual patient samples
Author / Creator:Syafrizayanti ; Lueong, Smiths S. ; Di, Cuixia ; Schaefer, Jonas V. ; Plückthun, Andreas ; Hoheisel, Jörg D.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-01, Vol.7 (1), p.39756-39756, Article 39756
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Functional metabolic phenotyping of human pancreatic ductal adenocarcinoma
Author / Creator:Heid, Irina ; Karakaya, Sinan ; Muench, Corinna ; Lueong, Smiths S ; Winkelkotte, Alina M ; Liffers, Sven T ; Godfrey, Laura ; Cheung, Phyllis Fy ; Savvatakis, Konstatinos ; Topping, Geoffrey J ; Englert, Florian ; Kritzner, Lukas ; Grashei, Martin ; Kunzke, Thomas ; Sun, Na ; Walch, Axel ; Tannapfel, Andrea ; Viebahn, Richard ; Wolters, Heiner ; Uhl, Waldemar ; Vangala, Deepak ; Markus-Smeets, Esther ; Aarntzen, Erik Hjg ; Rauh, Daniel ; Hoheisel, Joerg ; Hellerschmied, Doris ; Hahn, Stephan ; Schilling, Franz ; Braren, Rickmer ; Trajkovic-Arsic, Marija ; Siveke, Jens T
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-07
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ArticlesPeer ReviewedFull Text
TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer
Author / Creator:Zhao, Ben ; Dierichs, Laura ; Gu, Jiang-Ning ; Trajkovic-Arsic, Marija ; Axel Hilger, Ralf ; Savvatakis, Konstantinos ; Vega-Rubin-de-Celis, Silvia ; Liffers, Sven-Thorsten ; Peña-Llopis, Samuel ; Behrens, Diana ; Hahn, Stephan ; Siveke, Jens T ; Lueong, Smiths S
Publisher:United States
Journal title:Cell death discovery, 2020-03, Vol.6 (1), p.12
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Key Regulatory Elements of the TGFbeta-LRRC15 Axis Predict Disease Progression and Immunotherapy Resistance Across Cancer Types
Author / Creator:Storey, Claire M ; Cheng, Michael ; Altai, Mohamed ; Park, Julie E ; Tran, Julie ; Lueong, Smiths S ; Thorek, Daniel Lj ; Mao, Liqun ; Wahed Zedan ; Yuen, Constance ; Ridley, Alexander ; Trajkovic-Arsic, Marija ; Herrmann, Ken ; Subudhi, Sumit K ; Siddiqui, Bilal A ; Lueckerath, Katharina ; Siveke, Jens ; Damoiseaux, Robert ; Yang, Xia ; Ulmert, David
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2024-11
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ArticlesFull Text
Persister state-directed transitioning and vulnerability in melanoma
Author / Creator:Chauvistré, Heike ; Batool Shannan ; Daignault, Sheena M ; Ju, Robert J ; Picard, Daniel ; Egetemaier, Stefanie ; Váraljai, Renáta ; Sechi, Antonio ; Kaschani, Farnusch ; Keminer, Oliver ; Stehbens, Samantha J ; Liu, Qin ; Yin, Xiangfan ; Jeyakumar, Kirujan ; Vogel, Felix C E ; Krepler, Clemens ; Rebecca, Vito W ; Kubat, Linda ; Lueong, Smiths S ; ster, Jan ; Horn, Susanne ; Remke, Marc ; Ehrmann, Michael ; Paschen, Annette ; Becker, Jürgen C ; Helfrich, Iris ; Rauh, Daniel ; Kaiser, Markus ; Gul, Sheraz ; Herlyn, Meenhard ; Rodríguez-López, José Neptuno ; Haass, Nikolas K ; Schadendorf, Dirk ; Roesch, Alexander
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-03
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Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression

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Persister state-directed transitioning and vulnerability in melanoma

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SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis

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Minimally invasive determination of pancreatic ductal adenocarcinoma (PDAC) subtype by means of circulating cell‐free RNA

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Plasma Next Generation Sequencing and Droplet Digital-qPCR-Based Quantification of Circulating Cell-Free RNA for Noninvasive Early Detection of Cancer

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Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotype

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TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer

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BCL-B Promotes Lung Cancer Invasiveness by Direct Inhibition of BOK

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The clinical utility of cfRNA for disease detection and surveillance: A proof of concept study in non‐small cell lung cancer

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Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma

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Serial Circulating Tumor DNA Mutational Status in Patients with KRAS -Mutant Metastatic Colorectal Cancer from the Phase 3 AIO KRK0207 Trial

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Molecular characterization of early breast cancer onset to understand disease phenotypes in African patients

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Personalised proteome analysis by means of protein microarrays made from individual patient samples

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Functional metabolic phenotyping of human pancreatic ductal adenocarcinoma

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TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer

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Key Regulatory Elements of the TGFbeta-LRRC15 Axis Predict Disease Progression and Immunotherapy Resistance Across Cancer Types

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Persister state-directed transitioning and vulnerability in melanoma

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