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Neoadjuvant chemotherapy and nivolumab in resectable non-small-cell lung cancer (NADIM): an open-label, multicentre, single-arm, phase 2 trial
Author / Creator:Provencio, Mariano, MD ; Nadal, Ernest, MD ; Insa, Amelia, MD ; García-Campelo, María Rosario, MD ; Casal-Rubio, Joaquín, MD ; Dómine, Manuel, MD ; Majem, Margarita, MD ; Rodríguez-Abreu, Delvys, MD ; Martínez-Martí, Alex, MD ; De Castro Carpeño, Javier, MD ; Cobo, Manuel, MD ; López Vivanco, Guillermo, MD ; Del Barco, Edel, MD ; Bernabé Caro, Reyes, MD ; Viñolas, Nuria, MD ; Barneto Aranda, Isidoro, MD ; Viteri, Santiago, MD ; Pereira, Eva, MSc ; Royuela, Ana, PhD ; Casarrubios, Marta, MSc ; Salas Antón, Clara, MD ; Parra, Edwin R, PhD ; Wistuba, Ignacio, MD ; Calvo, Virginia, MD ; Laza-Briviesca, Raquel, MSc ; Romero, Atocha, PhD ; Massuti, Bartomeu, MD ; Cruz-Bermúdez, Alberto, PhD
Publisher:London: Elsevier Ltd
Journal title:The lancet oncology, 2020-11, Vol.21 (11), p.1413-1422
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Osimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer
Author / Creator:Wu, Yi-Long ; Tsuboi, Masahiro ; He, Jie ; John, Thomas ; Grohe, Christian ; Majem, Margarita ; Goldman, Jonathan W ; Laktionov, Konstantin ; Kim, Sang-We ; Kato, Terufumi ; Vu, Huu-Vinh ; Lu, Shun ; Lee, Kye-Young ; Akewanlop, Charuwan ; Yu, Chong-Jen ; de Marinis, Filippo ; Bonanno, Laura ; Domine, Manuel ; Shepherd, Frances A ; Zeng, Lingmin ; Hodge, Rachel ; Atasoy, Ajlan ; Rukazenkov, Yuri ; Herbst, Roy S
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-10, Vol.383 (18), p.1711-1723
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Osimertinib for pretreated EGFR Thr790Met-positive advanced non-small-cell lung cancer (AURA2): a multicentre, open-label, single-arm, phase 2 study
Author / Creator:Goss, Glenwood, Dr Prof ; Tsai, Chun-Ming, Prof ; Shepherd, Frances A, Prof ; Bazhenova, Lyudmila, Prof ; Lee, Jong Seok, MD ; Chang, Gee-Chen, MD ; Crino, Lucio, MD ; Satouchi, Miyako, MD ; Chu, Quincy, MD ; Hida, Toyoaki, MD ; Han, Ji-Youn, Prof ; Juan, Oscar, MD ; Dunphy, Frank, Prof ; Nishio, Makoto, MD ; Kang, Jin-Hyoung, MD ; Majem, Margarita, MD ; Mann, Helen, MSc ; Cantarini, Mireille, MD ; Ghiorghiu, Serban, MD ; Mitsudomi, Tetsuya, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-12, Vol.17 (12), p.1643-1652
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Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer
Author / Creator:Wakelee, Heather ; Liberman, Moishe ; Kato, Terufumi ; Tsuboi, Masahiro ; Lee, Se-Hoon ; Gao, Shugeng ; Chen, Ke-Neng ; Dooms, Christophe ; Majem, Margarita ; Eigendorff, Ekkehard ; Martinengo, Gastón L. ; Bylicki, Olivier ; Rodríguez-Abreu, Delvys ; Chaft, Jamie E. ; Novello, Silvia ; Yang, Jing ; Keller, Steven M. ; Samkari, Ayman ; Spicer, Jonathan D.
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-08, Vol.389 (6), p.491-503
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Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
Author / Creator:Herbst, Roy S, Prof ; Baas, Paul, Prof ; Kim, Dong-Wan, MD ; Felip, Enriqueta, MD ; Pérez-Gracia, José L, MD ; Han, Ji-Youn, Prof ; Molina, Julian, MD ; Kim, Joo-Hang, Prof ; Arvis, Catherine Dubos, MD ; Ahn, Myung-Ju, Prof ; Majem, Margarita, MD ; Fidler, Mary J, MD ; de Castro, Gilberto, MD ; Garrido, Marcelo, MD ; Lubiniecki, Gregory M, MD ; Shentu, Yue, PhD ; Im, Ellie, MD ; Dolled-Filhart, Marisa, PhD ; Garon, Edward B, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-04, Vol.387 (10027), p.1540-1550
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Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer
Author / Creator:Chmielecki, Juliann ; Gray, Jhanelle E. ; Cheng, Ying ; Ohe, Yuichiro ; Imamura, Fumio ; Cho, Byoung Chul ; Lin, Meng-Chih ; Majem, Margarita ; Shah, Riyaz ; Rukazenkov, Yuri ; Todd, Alexander ; Markovets, Aleksandra ; Barrett, J. Carl ; Hartmaier, Ryan J. ; Ramalingam, Suresh S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-02, Vol.14 (1), p.1070-1070, Article 1070
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Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer
Author / Creator:Rosell, Rafael ; Moran, Teresa ; Queralt, Cristina ; Porta, Rut ; Cardenal, Felipe ; Camps, Carlos ; Majem, Margarita ; Lopez-Vivanco, Guillermo ; Isla, Dolores ; Provencio, Mariano ; Insa, Amelia ; Massuti, Bartomeu ; Gonzalez-Larriba, Jose Luis ; Paz-Ares, Luis ; Bover, Isabel ; Garcia-Campelo, Rosario ; Moreno, Miguel Angel ; Catot, Silvia ; Rolfo, Christian ; Reguart, Noemi ; Palmero, Ramon ; Sánchez, José Miguel ; Bastus, Roman ; Mayo, Clara ; Bertran-Alamillo, Jordi ; Molina, Miguel Angel ; Sanchez, Jose Javier ; Taron, Miquel
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2009-09, Vol.361 (10), p.958-967
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Clinical activity of a htert (vx-001) cancer vaccine as post-chemotherapy maintenance immunotherapy in patients with stage IV non-small cell lung cancer: final results of a randomised phase 2 clinical...
Author / Creator:Gridelli, Cesare ; Ciuleanu, Tudor ; Domine, Manuel ; Szczesna, Aleksandra ; Bover, Isabel ; Cobo, Manuel ; Kentepozidis, Nikolaos ; Zarogoulidis, Konstantinos ; Kalofonos, Charalabos ; Kazarnowisz, Andrzej ; Korozan, Magdalena ; de las Penas, Ramon ; Majem, Margarita ; Chella, Antonio ; Griesinger, Frank ; Bournakis, Evangelos ; Sadjadian, Parvis ; Kotsakis, Athanasios ; Chinet, Thierry ; Syrigos, Kostantinos N. ; Correale, Pierpaolo ; Gallou, Catherine ; Jamet, Jeanne- Menez ; Vetsika, Eleni- Kyriaki ; Kosmatopoulos, Kostas ; Georgoulias, Vassilis
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-05, Vol.122 (10), p.1461-1466
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Prospective detection of mutations in cerebrospinal fluid, pleural effusion, and ascites of advanced cancer patients to guide treatment decisions
Author / Creator:Villatoro, Sergio ; Mayo‐de‐las‐Casas, Clara ; Jordana‐Ariza, Núria ; Viteri‐Ramírez, Santiago ; Garzón‐Ibañez, Mónica ; Moya‐Horno, Irene ; García‐Peláez, Beatriz ; González‐Cao, María ; Malapelle, Umberto ; Balada‐Bel, Ariadna ; Martínez‐Bueno, Alejandro ; Campos, Raquel ; Reguart, Noemí ; Majem, Margarita ; Blanco, Remei ; Blasco, Ana ; Catalán, María J. ; González, Xavier ; Troncone, Giancarlo ; Karachaliou, Niki ; Rosell, Rafael ; Molina‐Vila, Miguel A.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2019-12, Vol.13 (12), p.2633-2645
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Perioperative chemotherapy and nivolumab in non-small-cell lung cancer (NADIM): 5-year clinical outcomes from a multicentre, single-arm, phase 2 trial
Author / Creator:Provencio, Mariano, Prof ; Nadal, Ernest, MD ; Insa, Amelia ; García Campelo, Rosario, MD ; Casal, Joaquín, MD ; Dómine, Manuel, MD ; Massuti, Bartomeu, MD ; Majem, Margarita, MD ; Rodríguez-Abreu, Delvys, MD ; Martínez-Martí, Alex, MD ; de Castro, Javier, MD ; Gómez de Antonio, David, MD ; Macia, Iván, MD ; Figueroa, Santiago, MD ; Fernández Vago, Luís, MD ; Calvo, Virginia, MD ; Palmero, Ramón, MD ; Sierra-Rodero, Belén, MSc ; Martínez-Toledo, Cristina, MSc ; Molina-Alejandre, Marta, MSc ; Serna-Blasco, Roberto, PhD ; Romero, Atocha, PhD ; Cruz-Bermúdez, Alberto, PhD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-11, Vol.25 (11), p.1453-1464
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Circulating leukocyte–platelet complexes as a predictive biomarker for the development of immune-related adverse events in advanced non-small cell lung cancer patients receiving anti-PD-(L)1 blocking...
Author / Creator:Zamora, Carlos ; Riudavets, Mariona ; Anguera, Georgia ; Alserawan, Letícia ; Sullivan, Ivana ; Barba, Andrés ; Serra, Jorgina ; Ortiz, M. Angels ; Gallardo, Pablo ; Perea, Lidia ; Gavira, Javier ; Barnadas, Agustí ; Majem, Margarita ; Vidal, Silvia
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2021-06, Vol.70 (6), p.1691-1704
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Author Correction: Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer
Author / Creator:Chmielecki, Juliann ; Gray, Jhanelle E. ; Cheng, Ying ; Ohe, Yuichiro ; Imamura, Fumio ; Cho, Byoung Chul ; Lin, Meng-Chih ; Majem, Margarita ; Shah, Riyaz ; Rukazenkov, Yuri ; Todd, Alexander ; Markovets, Aleksandra ; Barrett, J. Carl ; Hartmaier, Ryan J. ; Ramalingam, Suresh S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-06, Vol.14 (1), p.3179-3179, Article 3179
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Pharmacokinetics and safety of capmatinib with food in patients with MET-dysregulated advanced solid tumors
Author / Creator:Moreno, Victor, MD, PhD ; Greil, Richard, MD ; Yachnin, Jeffrey, MD, PhD ; Majem, Margarita, MD, PhD ; Wermke, Martin, MD ; Arkenau, Hendrik-Tobias, MD, PhD ; Basque, Jean-Rene, PhD ; Nidamarthy, Prasanna Kumar, MSc ; Kapoor, Shruti, MD ; Cui, Xiaoming, PhD ; Giovannini, Monica, MD
Publisher:Bridgewater: Elsevier Inc
Journal title:Clinical therapeutics, 2021-06, Vol.43 (6), p.1092-1111
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Tumor microenvironment gene expression profiles associated to complete pathological response and disease progression in resectable NSCLC patients treated with neoadjuvant chemoimmunotherapy
Author / Creator:Casarrubios, Marta ; Provencio, Mariano ; Nadal, Ernest ; Insa, Amelia ; del Rosario García-Campelo, María ; Lázaro-Quintela, Martín ; Dómine, Manuel ; Majem, Margarita ; Rodriguez-Abreu, Delvys ; Martinez-Marti, Alex ; De Castro Carpeño, Javier ; Cobo, Manuel ; López Vivanco, Guillermo ; Del Barco, Edel ; Bernabé, Reyes ; Viñolas, Nuria ; Barneto Aranda, Isidoro ; Massuti, Bartomeu ; Sierra-Rodero, Belén ; Martinez-Toledo, Cristina ; Fernández-Miranda, Ismael ; Serna-Blanco, Roberto ; Romero, Atocha ; Calvo, Virginia ; Cruz-Bermúdez, Alberto
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2022-09, Vol.10 (9), p.e005320
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BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer
Author / Creator:Karachaliou, Niki ; Codony-Servat, Jordi ; Teixidó, Cristina ; Pilotto, Sara ; Drozdowskyj, Ana ; Codony-Servat, Carles ; Giménez-Capitán, Ana ; Molina-Vila, Miguel Angel ; Bertrán-Alamillo, Jordi ; Gervais, Radj ; Massuti, Bartomeu ; Morán, Teresa ; Majem, Margarita ; Felip, Enriqueta ; Carcereny, Enric ; García-Campelo, Rosario ; Viteri, Santiago ; González-Cao, María ; Morales-Espinosa, Daniela ; Verlicchi, Alberto ; Crisetti, Elisabetta ; Chaib, Imane ; Santarpia, Mariacarmela ; Luis Ramírez, José ; Bosch-Barrera, Joaquim ; Felipe Cardona, Andrés ; de Marinis, Filippo ; López-Vivanco, Guillermo ; Miguel Sánchez, José ; Vergnenegre, Alain ; Sánchez Hernández, José Javier ; Sperduti, Isabella ; Bria, Emilio ; Rosell, Rafael
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-12, Vol.5 (1), p.17499, Article 17499
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ERCC1 and ERCC2 Polymorphisms Predict the Efficacy and Toxicity of Platinum-Based Chemotherapy in Small Cell Lung Cancer
Author / Creator:Barba, Andrés ; López-Vilaró, Laura ; Ferre, Malena ; Majem, Margarita ; Martinez-Recio, Sergio ; Bell, Olga ; Arranz, María J ; Salazar, Juliana ; Sullivan, Ivana
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2024-09, Vol.16 (9), p.1121
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Author Correction: BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer
Author / Creator:Karachaliou, Niki ; Codony-Servat, Jordi ; Teixidó, Cristina ; Pilotto, Sara ; Drozdowskyj, Ana ; Codony-Servat, Carles ; Giménez-Capitán, Ana ; Molina-Vila, Miguel Angel ; Bertrán-Alamillo, Jordi ; Gervais, Radj ; Massuti, Bartomeu ; Morán, Teresa ; Majem, Margarita ; Felip, Enriqueta ; Carcereny, Enric ; García-Campelo, Rosario ; Viteri, Santiago ; González-Cao, María ; Morales-Espinosa, Daniela ; Verlicchi, Alberto ; Crisetti, Elisabetta ; Chaib, Imane ; Santarpia, Mariacarmela ; Luis Ramírez, José ; Bosch-Barrera, Joaquim ; Felipe Cardona, Andrés ; de Marinis, Filippo ; López-Vivanco, Guillermo ; Miguel Sánchez, José ; Vergnenegre, Alain ; Sánchez Hernández, José Javier ; Sperduti, Isabella ; Bria, Emilio ; Rosell, Rafael
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-03, Vol.13 (1), p.3620-3620, Article 3620
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Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain: OSIREX-Spanish Lung Cancer Group
Author / Creator:Provencio, Mariano ; Terrasa, Josefa ; Garrido, Pilar ; Campelo, Rosario García ; Aparisi, Francisco ; Diz, Pilar ; Aguiar, David ; García-Giron, Carlos ; Hidalgo, Julia ; Aguado, Carlos ; González, Jorge García ; Esteban, Emilio ; Gómez-Aldavarí, Lorenzo ; Moran, Teresa ; Juan, Oscar ; Chara, Luís Enrique ; Marti, Juan L ; Castro, Rafael López ; Ortega, Ana Laura ; Moreno, Elia Martínez ; Coves, Juan ; Sánchez Peña, Ana M ; Bosch-Barrera, Joaquim ; Gastaldo, Amparo Sánchez ; Núñez, Natalia Fernández ; Del Barco, Edel ; Cobo, Manuel ; Isla, Dolores ; Majem, Margarita ; Navarro, Fátima ; Calvo, Virginia
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2021-03, Vol.21 (1), p.230-230, Article 230
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Comprehensive cross‐platform comparison of methods for non‐invasive EGFR mutation testing: results of the RING observational trial
Author / Creator:Romero, Atocha ; Jantus‐Lewintre, Eloisa ; García‐Peláez, Beatriz ; Royuela, Ana ; Insa, Amelia ; Cruz, Patricia ; Collazo, Ana ; Pérez Altozano, Javier ; Vidal, Oscar Juan ; Diz, Pilar ; Cobo, Manuel ; Hernández, Berta ; Vázquez Estevez, Sergio ; Benítez, Gretel ; Guirado, Maria ; Majem, Margarita ; Bernabé, Reyes ; Ortega, Ana Laura ; Blasco, Ana ; Bosch‐Barrera, Joaquim ; Jurado, Jose M. ; García González, Jorge ; Viteri, Santiago ; Garcia Giron, Carlos ; Massutí, Bartomeu ; Lopez Martín, Ana ; Rodriguez‐Festa, Alejandro ; Calabuig‐Fariñas, Silvia ; Molina‐Vila, Miguel Ángel ; Provencio, Mariano
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2021-01, Vol.15 (1), p.43-56
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Blood biomarkers associated to complete pathological response on NSCLC patients treated with neoadjuvant chemoimmunotherapy included in NADIM clinical trial
Author / Creator:Laza‐Briviesca, Raquel ; Cruz‐Bermúdez, Alberto ; Nadal, Ernest ; Insa, Amelia ; García‐Campelo, María del Rosario ; Huidobro, Gerardo ; Dómine, Manuel ; Majem, Margarita ; Rodríguez‐Abreu, Delvys ; Martínez‐Martí, Alex ; De Castro Carpeño, Javier ; Cobo, Manuel ; López Vivanco, Guillermo ; Del Barco, Edel ; Bernabé Caro, Reyes ; Viñolas, Nuria ; Barneto Aranda, Isidoro ; Viteri, Santiago ; Massuti, Bartomeu ; Casarrubios, Marta ; Sierra‐Rodero, Belén ; Tarín, Carlos ; García‐Grande, Aránzazu ; Haymaker, Cara ; Wistuba, Ignacio I. ; Romero, Atocha ; Franco, Fernando ; Provencio, Mariano
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational medicine, 2021-07, Vol.11 (7), p.e491-n/a
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Neoadjuvant chemotherapy and nivolumab in resectable non-small-cell lung cancer (NADIM): an open-label, multicentre, single-arm, phase 2 trial

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Osimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer

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Osimertinib for pretreated EGFR Thr790Met-positive advanced non-small-cell lung cancer (AURA2): a multicentre, open-label, single-arm, phase 2 study

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Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer

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Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial

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Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer

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Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer

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Clinical activity of a htert (vx-001) cancer vaccine as post-chemotherapy maintenance immunotherapy in patients with stage IV non-small cell lung cancer: final results of a randomised phase 2 clinical...

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Prospective detection of mutations in cerebrospinal fluid, pleural effusion, and ascites of advanced cancer patients to guide treatment decisions

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Perioperative chemotherapy and nivolumab in non-small-cell lung cancer (NADIM): 5-year clinical outcomes from a multicentre, single-arm, phase 2 trial

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Circulating leukocyte–platelet complexes as a predictive biomarker for the development of immune-related adverse events in advanced non-small cell lung cancer patients receiving anti-PD-(L)1 blocking...

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Author Correction: Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer

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Pharmacokinetics and safety of capmatinib with food in patients with MET-dysregulated advanced solid tumors

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Tumor microenvironment gene expression profiles associated to complete pathological response and disease progression in resectable NSCLC patients treated with neoadjuvant chemoimmunotherapy

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BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer

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ERCC1 and ERCC2 Polymorphisms Predict the Efficacy and Toxicity of Platinum-Based Chemotherapy in Small Cell Lung Cancer

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Author Correction: BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer

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Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain: OSIREX-Spanish Lung Cancer Group

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Comprehensive cross‐platform comparison of methods for non‐invasive EGFR mutation testing: results of the RING observational trial

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Blood biomarkers associated to complete pathological response on NSCLC patients treated with neoadjuvant chemoimmunotherapy included in NADIM clinical trial

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