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CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer
Author / Creator:McCleland, Mark L ; Mesh, Kathryn ; Lorenzana, Edward ; Chopra, Vivek S ; Segal, Ehud ; Watanabe, Colin ; Haley, Benjamin ; Mayba, Oleg ; Yaylaoglu, Murat ; Gnad, Florian ; Firestein, Ron
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2016-02, Vol.126 (2), p.639-652
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Molecular determinants of response to PD-L1 blockade across tumor types
Author / Creator:Banchereau, Romain ; Leng, Ning ; Zill, Oliver ; Sokol, Ethan ; Liu, Gengbo ; Pavlick, Dean ; Maund, Sophia ; Liu, Li-Fen ; Kadel, Edward ; Baldwin, Nicole ; Jhunjhunwala, Suchit ; Nickles, Dorothee ; Assaf, Zoe June ; Bower, Daniel ; Patil, Namrata ; McCleland, Mark ; Shames, David ; Molinero, Luciana ; Huseni, Mahrukh ; Sanjabi, Shomyseh ; Cummings, Craig ; Mellman, Ira ; Mariathasan, Sanjeev ; Hegde, Priti ; Powles, Thomas
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-06, Vol.12 (1), p.3969-3969, Article 3969
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Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition
Author / Creator:Boudreau, Aaron ; Purkey, Hans E ; Hitz, Anna ; Robarge, Kirk ; Peterson, David ; Labadie, Sharada ; Kwong, Mandy ; Hong, Rebecca ; Gao, Min ; Del Nagro, Christopher ; Pusapati, Raju ; Ma, Shuguang ; Salphati, Laurent ; Pang, Jodie ; Zhou, Aihe ; Lai, Tommy ; Li, Yingjie ; Chen, Zhongguo ; Wei, Binqing ; Yen, Ivana ; Sideris, Steve ; McCleland, Mark ; Firestein, Ron ; Corson, Laura ; Vanderbilt, Alex ; Williams, Simon ; Daemen, Anneleen ; Belvin, Marcia ; Eigenbrot, Charles ; Jackson, Peter K ; Malek, Shiva ; Hatzivassiliou, Georgia ; Sampath, Deepak ; Evangelista, Marie ; O'Brien, Thomas
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2016-10, Vol.12 (10), p.779-786
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Clinical efficacy of atezolizumab plus bevacizumab and chemotherapy in KRAS-mutated non-small cell lung cancer with STK11, KEAP1, or TP53 comutations: subgroup results from the phase III IMpower150 tr...
Author / Creator:West, Howard Jack ; McCleland, Mark ; Cappuzzo, Federico ; Reck, Martin ; Mok, Tony SK ; Jotte, Robert M ; Nishio, Makoto ; Kim, Eugene ; Morris, Stefanie ; Zou, Wei ; Shames, David ; Das Thakur, Meghna ; Shankar, Geetha ; Socinski, Mark A
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2022-02, Vol.10 (2), p.e003027
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Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade
Author / Creator:Banchereau, Romain ; Chitre, Avantika S. ; Scherl, Alexis ; Wu, Thomas D. ; Patil, Namrata S. ; de Almeida, Patricia ; Kadel, III, Edward E. ; Madireddi, Shravan ; Au-Yeung, Amelia ; Takahashi, Chikara ; Chen, Ying-Jiun ; Modrusan, Zora ; McBride, Jacqueline ; Nersesian, Rhea ; El-Gabry, Ehab A. ; Robida, Mark D. ; Hung, Jeffrey C. ; Kowanetz, Marcin ; Zou, Wei ; McCleland, Mark ; Caplazi, Patrick ; Eshgi, Shadi Toghi ; Koeppen, Hartmut ; Hegde, Priti S. ; Mellman, Ira ; Mathews, W. Rodney ; Powles, Thomas ; Mariathasan, Sanjeev ; Grogan, Jane ; O'Gorman, William E
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2021-04, Vol.9 (4), p.e002231
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ArticlesPeer ReviewedFull Text
Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae
Author / Creator:Ficarro, Scott B. ; McCleland, Mark L. ; Stukenberg, P. Todd ; Burke, Daniel J. ; Ross, Mark M. ; Shabanowitz, Jeffrey ; Hunt, Donald F. ; White, Forest M.
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2002-03, Vol.20 (3), p.301-305
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Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer
Author / Creator:Liu, Jinfeng ; McCleland, Mark ; Stawiski, Eric W. ; Gnad, Florian ; Mayba, Oleg ; Haverty, Peter M. ; Durinck, Steffen ; Chen, Ying-Jiun ; Klijn, Christiaan ; Jhunjhunwala, Suchit ; Lawrence, Michael ; Liu, Hanbin ; Wan, Yinan ; Chopra, Vivek ; Yaylaoglu, Murat B. ; Yuan, Wenlin ; Ha, Connie ; Gilbert, Houston N. ; Reeder, Jens ; Pau, Gregoire ; Stinson, Jeremy ; Stern, Howard M. ; Manning, Gerard ; Wu, Thomas D. ; Neve, Richard M. ; de Sauvage, Frederic J. ; Modrusan, Zora ; Seshagiri, Somasekar ; Firestein, Ron ; Zhang, Zemin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-05, Vol.5 (1), p.3830-3830, Article 3830
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Comparison of SP263 and 22C3 immunohistochemistry PD-L1 assays for clinical efficacy of adjuvant atezolizumab in non-small cell lung cancer: results from the randomized phase III IMpower010 trial
Author / Creator:Zhou, Caicun ; Srivastava, Minu K ; Xu, Hao ; Felip, Enriqueta ; Wakelee, Heather ; Altorki, Nasser ; Reck, Martin ; Liersch, Rüdiger ; Kryzhanivska, Anna ; Oizumi, Satoshi ; Tanaka, Hiroshi ; Hamm, John ; McCune, Steven L ; Bennett, Elizabeth ; Gitlitz, Barbara ; McNally, Virginia ; Ballinger, Marcus ; McCleland, Mark ; Zou, Wei ; Das Thakur, Meghna ; Novello, Silvia
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-10, Vol.11 (10), p.e007047
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831 Exact Shapley values for explaining complex machine learning based molecular tests of checkpoint inhibitors: potential utility for patients, physicians, and translational research
Author / Creator:Roder, Heinrich ; Net, Lelia ; Roder, Joanna ; Campbell, Thomas ; McCleland, Mark ; Zou, Wei ; Srivastava, Minu ; Shames, David ; Maguire, Laura ; Georgantas, Robert
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A870-A871
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26 Validation of the Primary Immune Response (PIR) test in advanced non-small cell lung cancer (NSCLC): blinded retrospective analyses from the POPLAR and OAK trials
Author / Creator:Roder, Heinrich ; Maguire, Laura ; Asmellash, Senait ; Rightmyer, Steven ; Norman, Patrick ; McCleland, Mark ; Zou, Wei ; Srivastava, Minu ; Net, Lelia ; Campbell, Thomas ; Shames, David ; Georgantas, Robert ; Roder, Joanna
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A30-A31
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28 Predictions of outcomes and benefit of immune checkpoint inhibitor treatment in NSCLC require information on both tumor and host biology
Author / Creator:Roder, Joanna ; Campbell, Thomas ; Asmellash, Senait ; Rightmyer, Steven ; Norman, Patrick ; Georgantas, Robert ; McCleland, Mark ; Zou, Wei ; Srivastava, Minu ; Net, Lelia ; Maguire, Laura ; Roder, Heinrich ; Shames, David
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A33-A33
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Role of Vector in Activation of T Cell Subsets in Immune Responses against the Secreted Transgene Product Factor IX
Author / Creator:Fields, Paul A. ; Kowalczyk, Dariusz W. ; Arruda, Valder R. ; Armstrong, Elina ; McCleland, Mark L. ; Hagstrom, J.Nathan ; Pasi, K.John ; Ertl, Hildegund C.J. ; Herzog, Roland W. ; High, Katherine A.
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2000-03, Vol.1 (3), p.225-235
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Adjuvant atezolizumab after adjuvant chemotherapy in resected stage IB–IIIA non-small-cell lung cancer (IMpower010): a randomised, multicentre, open-label, phase 3 trial
Author / Creator:Felip, Enriqueta ; Altorki, Nasser ; Zhou, Caicun ; Csőszi, Tibor ; Vynnychenko, Ihor ; Goloborodko, Oleksandr ; Luft, Alexander ; Akopov, Andrey ; Martinez-Marti, Alex ; Kenmotsu, Hirotsugu ; Chen, Yuh-Min ; Chella, Antonio ; Sugawara, Shunichi ; Voong, David ; Wu, Fan ; Yi, Jing ; Deng, Yu ; McCleland, Mark ; Bennett, Elizabeth ; Gitlitz, Barbara ; Wakelee, Heather
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2021-10, Vol.398 (10308), p.1344-1357
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Atezolizumab for First-Line Treatment of PD-L1–Selected Patients with NSCLC
Author / Creator:Herbst, Roy S ; Giaccone, Giuseppe ; de Marinis, Filippo ; Reinmuth, Niels ; Vergnenegre, Alain ; Barrios, Carlos H ; Morise, Masahiro ; Felip, Enriqueta ; Andric, Zoran ; Geater, Sarayut ; Özgüroğlu, Mustafa ; Zou, Wei ; Sandler, Alan ; Enquist, Ida ; Komatsubara, Kimberly ; Deng, Yu ; Kuriki, Hiroshi ; Wen, Xiaohui ; McCleland, Mark ; Mocci, Simonetta ; Jassem, Jacek ; Spigel, David R
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-10, Vol.383 (14), p.1328-1339
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USP7 small-molecule inhibitors interfere with ubiquitin binding
Author / Creator:Kategaya, Lorna ; Di Lello, Paola ; Rougé, Lionel ; Pastor, Richard ; Clark, Kevin R. ; Drummond, Jason ; Kleinheinz, Tracy ; Lin, Eva ; Upton, John-Paul ; Prakash, Sumit ; Heideker, Johanna ; McCleland, Mark ; Ritorto, Maria Stella ; Alessi, Dario R. ; Trost, Matthias ; Bainbridge, Travis W. ; Kwok, Michael C. M. ; Ma, Taylur P. ; Stiffler, Zachary ; Brasher, Bradley ; Tang, Yinyan ; Jaishankar, Priyadarshini ; Hearn, Brian R. ; Renslo, Adam R. ; Arkin, Michelle R. ; Cohen, Frederick ; Yu, Kebing ; Peale, Frank ; Gnad, Florian ; Chang, Matthew T. ; Klijn, Christiaan ; Blackwood, Elizabeth ; Martin, Scott E. ; Forrest, William F. ; Ernst, James A. ; Ndubaku, Chudi ; Wang, Xiaojing ; Beresini, Maureen H. ; Tsui, Vickie ; Schwerdtfeger, Carsten ; Blake, Robert A. ; Murray, Jeremy ; Maurer, Till ; Wertz, Ingrid E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-10, Vol.550 (7677), p.534-538
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ArticlesPeer ReviewedFull Text
O81 IMpower110: interim overall survival (OS) analysis of a phase III study of atezolizumab (ATEZO) monotherapy vs platinum-based chemotherapy (CHEMO) as first-line (1L) treatment in PD-L1–selected NS...
Author / Creator:Herbst, Roy ; Marinis, Filippo De ; Giaccone, Giuseppe ; Reinmuth, Niels ; Vergnenegre, Alain ; Barrios, Carlos ; Morise, Masahiro ; Font, Enriqueta ; Andric, Zoran ; Geater, Sarayut ; Ozguroglu, Mustafa ; Mocci, Simonetta ; McCleland, Mark ; Enquist, Ida ; Komatsubara, Kim ; Deng, Yu ; Kuriki, Hiroshi ; Wen, Xiaohui ; Jassem, Jacek ; Spigel, David
Publisher:London: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2020-04, Vol.8 (Suppl 1), p.A1-A1
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ReportsFull Text
CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer
Author / Creator:McCleland, Mark L ; Mesh, Kathryn ; Lorenzana, Edward ; Chopra, Vivek S ; Segal, Ehud ; Watanabe, Colin ; Haley, Benjamin ; Mayba, Oleg ; Yaylaoglu, Murat ; Gnad, Florian ; Firestein, Ron
Publisher:American Society for Clinical Investigation
Journal title:Journal of Clinical Investigation, 2016, p.639
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ReportsFull Text
CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer
Author / Creator:McCleland, Mark L ; Mesh, Kathryn ; Lorenzana, Edward ; Chopra, Vivek S ; Segal, Ehud ; Watanabe, Colin ; Haley, Benjamin ; Mayba, Oleg ; Yaylaoglu, Murat ; Gnad, Florian ; Firestein, Ron
Publisher:American Society for Clinical Investigation
Journal title:Journal of Clinical Investigation, 2016, p.639
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ReportsFull Text
USP7 small-molecule inhibitors interfere with ubiquitin binding
Author / Creator:Kategaya, Lorna ; Di Lello, Paola ; Roug, Lionel ; Pastor, Richard ; Clark, Kevin R ; Drummond, Jason ; Kleinheinz, Tracy ; Lin, Eva ; Upton, John-Paul ; Prakash, Sumit ; Heideker, Johanna ; McCleland, Mark ; Ritorto, Maria Stella ; Alessi, Dario R ; Trost, Matthias ; Bainbridge, Travis W ; Kwok, Michael C. M ; Ma, Taylur P ; Stiffler, Zachary ; Brasher, Bradley ; Tang, Yinyan ; Jaishankar, Priyadarshini ; Hearn, Brian R ; Renslo, Adam R ; Arkin, Michelle R ; Cohen, Frederick ; Yu, Kebing ; Peale, Frank ; Gnad, Florian ; Chang, Matthew T ; Klijn, Christiaan ; Blackwood, Elizabeth ; Martin, Scott E ; Forrest, William F ; Ernst, James A ; Ndubaku, Chudi ; Wang, Xiaojing ; Beresini, Maureen H ; Tsui, Vickie ; Schwerdtfeger, Carsten ; Blake, Robert A ; Murray, Jeremy ; Maurer, Till ; Wertz, Ingrid E
Publisher:Nature Publishing Group
Journal title:Nature, 2017, Vol.550 (7677), p.534
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ReportsFull Text
USP7 small-molecule inhibitors interfere with ubiquitin binding
Author / Creator:Kategaya, Lorna ; Di Lello, Paola ; Roug, Lionel ; Pastor, Richard ; Clark, Kevin R ; Drummond, Jason ; Kleinheinz, Tracy ; Lin, Eva ; Upton, John-Paul ; Prakash, Sumit ; Heideker, Johanna ; McCleland, Mark ; Ritorto, Maria Stella ; Alessi, Dario R ; Trost, Matthias ; Bainbridge, Travis W ; Kwok, Michael C. M ; Ma, Taylur P ; Stiffler, Zachary ; Brasher, Bradley ; Tang, Yinyan ; Jaishankar, Priyadarshini ; Hearn, Brian R ; Renslo, Adam R ; Arkin, Michelle R ; Cohen, Frederick ; Yu, Kebing ; Peale, Frank ; Gnad, Florian ; Chang, Matthew T ; Klijn, Christiaan ; Blackwood, Elizabeth ; Martin, Scott E ; Forrest, William F ; Ernst, James A ; Ndubaku, Chudi ; Wang, Xiaojing ; Beresini, Maureen H ; Tsui, Vickie ; Schwerdtfeger, Carsten ; Blake, Robert A ; Murray, Jeremy ; Maurer, Till ; Wertz, Ingrid E
Publisher:Nature Publishing Group
Journal title:Nature, 2017, Vol.550 (7677), p.534
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CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer

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Molecular determinants of response to PD-L1 blockade across tumor types

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Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition

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Clinical efficacy of atezolizumab plus bevacizumab and chemotherapy in KRAS-mutated non-small cell lung cancer with STK11, KEAP1, or TP53 comutations: subgroup results from the phase III IMpower150 tr...

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Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade

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Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae

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Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer

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Comparison of SP263 and 22C3 immunohistochemistry PD-L1 assays for clinical efficacy of adjuvant atezolizumab in non-small cell lung cancer: results from the randomized phase III IMpower010 trial

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831 Exact Shapley values for explaining complex machine learning based molecular tests of checkpoint inhibitors: potential utility for patients, physicians, and translational research

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26 Validation of the Primary Immune Response (PIR) test in advanced non-small cell lung cancer (NSCLC): blinded retrospective analyses from the POPLAR and OAK trials

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28 Predictions of outcomes and benefit of immune checkpoint inhibitor treatment in NSCLC require information on both tumor and host biology

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Role of Vector in Activation of T Cell Subsets in Immune Responses against the Secreted Transgene Product Factor IX

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Adjuvant atezolizumab after adjuvant chemotherapy in resected stage IB–IIIA non-small-cell lung cancer (IMpower010): a randomised, multicentre, open-label, phase 3 trial

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Atezolizumab for First-Line Treatment of PD-L1–Selected Patients with NSCLC

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USP7 small-molecule inhibitors interfere with ubiquitin binding

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O81 IMpower110: interim overall survival (OS) analysis of a phase III study of atezolizumab (ATEZO) monotherapy vs platinum-based chemotherapy (CHEMO) as first-line (1L) treatment in PD-L1–selected NS...

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CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer

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CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer

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USP7 small-molecule inhibitors interfere with ubiquitin binding

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USP7 small-molecule inhibitors interfere with ubiquitin binding

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