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ArticlesPeer ReviewedFull Text
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1
Author / Creator:Curtis, Anne M. ; Fagundes, Caio T. ; Yang, Guangrui ; Palsson-McDermott, Eva M. ; Wochal, Paulina ; McGettrick, Anne F. ; Foley, Niamh H. ; Early, James O. ; Chen, Lihong ; Zhang, Hanrui ; Xue, Chenyi ; Geiger, Sarah S. ; Hokamp, Karsten ; Reilly, Muredach P. ; Coogan, Andrew N. ; Vigorito, Elena ; FitzGerald, Garret A. ; O’Neill, Luke A. J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (23), p.7231-7236
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ArticlesPeer ReviewedFull Text
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway
Author / Creator:Palsson-McDermott, Eva M ; Doyle, Sarah L ; McGettrick, Anne F ; Hardy, Matthew ; Husebye, Harald ; Banahan, Kathy ; Gong, Mei ; Golenbock, Douglas ; Espevik, Terje ; O'Neill, Luke A J
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2009-06, Vol.10 (6), p.579-586
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ArticlesPeer ReviewedFull Text
The Myristoylation of TRIF-Related Adaptor Molecule Is Essential for Toll-Like Receptor 4 Signal Transduction
Author / Creator:Rowe, Daniel C. ; McGettrick, Anne F. ; Latz, Eicke ; Monks, Brian G. ; Gay, Nicholas J. ; Yamamoto, Masahiro ; Akira, Shizuo ; O'Neill, Luke A. ; Fitzgerald, Katherine A. ; Golenbock, Douglas T.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-04, Vol.103 (16), p.6299-6304
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ArticlesPeer ReviewedFull Text
Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death
Author / Creator:de Koning, Pieter J. A. ; Kummer, J. Alain ; de Poot, Stefanie A. H. ; Quadir, Razi ; Broekhuizen, Roel ; McGettrick, Anne F. ; Higgins, Wayne J. ; Devreese, Bart ; Worrall, D. Margaret ; Bovenschen, Niels
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-08, Vol.6 (8), p.e22645
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ArticlesPeer ReviewedFull Text
Trif-Related Adapter Molecule Is Phosphorylated by PKCε during Toll-Like Receptor 4 Signaling
Author / Creator:McGettrick, Anne F. ; Brint, Elizabeth K. ; Palsson-McDermott, Eva M. ; Rowe, Daniel C. ; Golenbock, Douglas T. ; Gay, Nicholas J. ; Fitzgerald, Katherine A. ; O'Neill, Luke A. J.
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (24), p.9196-9201
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ArticlesPeer ReviewedFull Text
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production
Author / Creator:Hooftman, Alexander ; Peace, Christian G. ; Ryan, Dylan G. ; Day, Emily A. ; Yang, Ming ; McGettrick, Anne F. ; Yin, Maureen ; Montano, Erica N. ; Huo, Lihong ; Toller-Kawahisa, Juliana E. ; Zecchini, Vincent ; Ryan, Tristram A. J. ; Bolado-Carrancio, Alfonso ; Casey, Alva M. ; Prag, Hiran A. ; Costa, Ana S. H. ; De Los Santos, Gabriela ; Ishimori, Mariko ; Wallace, Daniel J. ; Venuturupalli, Swamy ; Nikitopoulou, Efterpi ; Frizzell, Norma ; Johansson, Cecilia ; Von Kriegsheim, Alexander ; Murphy, Michael P. ; Jefferies, Caroline ; Frezza, Christian ; O’Neill, Luke A. J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-03, Vol.615 (7952), p.490-498
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ArticlesPeer ReviewedFull Text
Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion
Author / Creator:McGettrick, Anne F. ; Corcoran, Sarah E. ; Barry, Paul J. G. ; McFarland, Jennifer ; Crès, Cécile ; Curtis, Anne M. ; Franklin, Edward ; Corr, Sinéad C. ; Mok, K. Hun ; Cummins, Eoin P. ; Taylor, Cormac T. ; O’Neill, Luke A. J. ; Nolan, Derek P.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (48), p.E7778-E7787
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ArticlesPeer ReviewedFull Text
The itaconate family of immunomodulators grows
Author / Creator:McGettrick, Anne F. ; O’Neill, Luke A. J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature metabolism, 2022-05, Vol.4 (5), p.499-500
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ArticlesPeer ReviewedFull Text
The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation
Author / Creator:Doyle, Sarah L. ; Husebye, Harald ; Connolly, Dympna J. ; Espevik, Terje ; O'Neill, Luke A.J. ; McGettrick, Anne F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2012-02, Vol.3 (1), p.707, Article 707
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ArticlesPeer ReviewedFull Text
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
Author / Creator:Mills, Evanna L. ; Ryan, Dylan G. ; Prag, Hiran A. ; Dikovskaya, Dina ; Menon, Deepthi ; Zaslona, Zbigniew ; Jedrychowski, Mark P. ; Costa, Ana S. H. ; Higgins, Maureen ; Hams, Emily ; Szpyt, John ; Runtsch, Marah C. ; King, Martin S. ; McGouran, Joanna F. ; Fischer, Roman ; Kessler, Benedikt M. ; McGettrick, Anne F. ; Hughes, Mark M. ; Carroll, Richard G. ; Booty, Lee M. ; Knatko, Elena V. ; Meakin, Paul J. ; Ashford, Michael L. J. ; Modis, Louise K. ; Brunori, Gino ; Sévin, Daniel C. ; Fallon, Padraic G. ; Caldwell, Stuart T. ; Kunji, Edmund R. S. ; Chouchani, Edward T. ; Frezza, Christian ; Dinkova-Kostova, Albena T. ; Hartley, Richard C. ; Murphy, Michael P. ; O’Neill, Luke A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-04, Vol.556 (7699), p.113-117
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ArticlesPeer ReviewedFull Text
Trypanosoma brucei metabolite indolepyruvate decreases HIF-1a and glycolysis in macrophages as a mechanism of innate immune evasion
Author / Creator:McGettrick, Anne F ; Corcoran, Sarah E ; Barry, Paul JG ; McFarland, Jennifer ; Crès, Cécile ; Curtis, Anne M ; Franklin, Edward ; Corr, Sinéad C ; Mok, K Hun ; Cummins, Eoin P ; Taylor, Cormac T ; O'Neill, Luke AJ ; Nolan, Derek P
Publisher:Washington: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (48), p.E7778-E7778
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ArticlesPeer ReviewedFull Text
Circadian control of innate immunity in macrophages by miR-155 targetingBmal1
Author / Creator:Curtis, Anne M. ; Fagundes, Caio T. ; Yang, Guangrui ; Palsson-McDermott, Eva M. ; Wochal, Paulina ; McGettrick, Anne F. ; Foley, Niamh H. ; Early, James O. ; Chen, Lihong ; Zhang, Hanrui ; Xue, Chenyi ; Geiger, Sarah S. ; Hokamp, Karsten ; Reilly, Muredach P. ; Coogan, Andrew N. ; Vigorito, Elena ; FitzGerald, Garret A. ; O’Neill, Luke A. J.
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (23), p.7231-7236
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ArticlesPeer ReviewedFull Text
Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling
Author / Creator:McGettrick, Anne F ; Brint, Elizabeth K ; Palsson-McDermott, Eva M ; Rowe, Daniel C ; Golenbock, Douglas T ; Gay, Nicholas J ; Fitzgerald, Katherine A ; O'Neill, Luke A J
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (24), p.9196
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Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1

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TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway

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The Myristoylation of TRIF-Related Adaptor Molecule Is Essential for Toll-Like Receptor 4 Signal Transduction

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Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death

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Trif-Related Adapter Molecule Is Phosphorylated by PKCε during Toll-Like Receptor 4 Signaling

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Macrophage fumarate hydratase restrains mtRNA-mediated interferon production

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Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion

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The itaconate family of immunomodulators grows

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The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation

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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

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Trypanosoma brucei metabolite indolepyruvate decreases HIF-1a and glycolysis in macrophages as a mechanism of innate immune evasion

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Circadian control of innate immunity in macrophages by miR-155 targetingBmal1

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Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling

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