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ArticlesPeer ReviewedFull Text
Suppression of lipopolysaccharide-induced COX-2 expression via p38MAPK, JNK, and C/EBPβ phosphorylation inhibition by furomagydarin A, a benzofuran glycoside from Magydaris pastinacea
Author / Creator:Huang, Shiu-Wen ; Hsu, Ming Jen ; Chen, Hsiu-Chen ; Meleddu, Rita ; Distinto, Simona ; Maccioni, Elias ; Cottiglia, Filippo
Publisher:England: Taylor & Francis Ltd
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2024-12, Vol.39 (1), p.2287420-2287420
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Privileged Scaffold Hybridization in the Design of Carbonic Anhydrase Inhibitors
Author / Creator:Secci, Daniela ; Sanna, Erica ; Distinto, Simona ; Onali, Alessia ; Lupia, Antonio ; Demuru, Laura ; Atzeni, Giulia ; Meleddu, Rita ; Cottiglia, Filippo ; Angeli, Andrea ; Supuran, Claudiu T. ; Maccioni, Elias
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-09, Vol.29 (18), p.4444
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Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase
Author / Creator:Meleddu, Rita ; Distinto, Simona ; Corona, Angela ; Tramontano, Enzo ; Bianco, Giulia ; Melis, Claudia ; Cottiglia, Filippo ; Maccioni, Elias
Publisher:Abingdon: Taylor & Francis Ltd
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2017-01, Vol.32 (1), p.136
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Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6
Author / Creator:Corona, Angela ; Meleddu, Rita ; Esposito, Francesca ; Distinto, Simona ; Bianco, Giulia ; Masaoka, Takashi ; Maccioni, Elias ; Menéndez-Arias, Luis ; Alcaro, Stefano ; Le Grice, Stuart F. J. ; Tramontano, Enzo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-01, Vol.11 (1), p.e0147225
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2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms
Author / Creator:Sequeira, Lisa ; Distinto, Simona ; Meleddu, Rita ; Gaspari, Marco ; Angeli, Andrea ; Cottiglia, Filippo ; Secci, Daniela ; Onali, Alessia ; Sanna, Erica ; Borges, Fernanda ; Uriarte, Eugenio ; Alcaro, Stefano ; Supuran, Claudiu T. ; Maccioni, Elias
Publisher:England: Taylor & Francis Ltd
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2270183-2270183
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ArticlesPeer ReviewedFull Text
Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors
Author / Creator:Melis, Claudia ; Meleddu, Rita ; Angeli, Andrea ; Distinto, Simona ; Bianco, Giulia ; Capasso, Clemente ; Cottiglia, Filippo ; Angius, Rossella ; Supuran, Claudiu T ; Maccioni, Elias
Publisher:Abingdon: Taylor & Francis Ltd
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2017-01, Vol.32 (1), p.73
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Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation
Author / Creator:Fois, Benedetta ; Distinto, Simona ; Meleddu, Rita ; Deplano, Serenella ; Maccioni, Elias ; Floris, Costantino ; Rosa, Antonella ; Nieddu, Mariella ; Caboni, Pierluigi ; Sissi, Claudia ; Angeli, Andrea ; Supuran, Claudiu T. ; Cottiglia, Filippo
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.539-548
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ArticlesPeer ReviewedFull Text
Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions
Author / Creator:Meleddu, Rita ; Corona, Angela ; Distinto, Simona ; Cottiglia, Filippo ; Deplano, Serenella ; Sequeira, Lisa ; Secci, Daniela ; Onali, Alessia ; Sanna, Erica ; Esposito, Francesca ; Cirone, Italo ; Ortuso, Francesco ; Alcaro, Stefano ; Tramontano, Enzo ; Mátyus, Péter ; Maccioni, Elias
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-06, Vol.26 (13), p.3821
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ArticlesPeer ReviewedFull Text
Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B
Author / Creator:Meleddu, Rita ; Distinto, Simona ; Cirilli, Roberto ; Alcaro, Stefano ; Yanez, Matilde ; Sanna, Maria Luisa ; Corona, Angela ; Melis, Claudia ; Bianco, Giulia ; Matyus, Peter ; Cottiglia, Filippo ; Maccioni, Elias
Publisher:Abingdon: Taylor & Francis Ltd
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2017-01, Vol.32 (1), p.270
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ArticlesPeer ReviewedFull Text
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor
Author / Creator:Corona, Angela ; Meleddu, Rita ; Esposito, Francesca ; Distinto, Simona ; Bianco, Giulia ; Maccioni, Elias ; Le Grice, Stuart SF ; Tramontano, Enzo
Publisher:London: BioMed Central
Journal title:Retrovirology, 2013-09, Vol.10 (S1), p.P19-P19, Article P19
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ArticlesPeer ReviewedFull Text
Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6: e0147225
Author / Creator:Corona, Angela ; Meleddu, Rita ; Esposito, Francesca ; Distinto, Simona ; Bianco, Giulia ; Masaoka, Takashi ; Maccioni, Elias ; Menendez-Arias, Luis ; Alcaro, Stefano ; Grice, F JLe
Journal title:PloS one, 2016-01, Vol.11 (1)
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Suppression of lipopolysaccharide-induced COX-2 expression via p38MAPK, JNK, and C/EBPβ phosphorylation inhibition by furomagydarin A, a benzofuran glycoside from Magydaris pastinacea

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Privileged Scaffold Hybridization in the Design of Carbonic Anhydrase Inhibitors

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Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase

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Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6

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2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms

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Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors

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Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation

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Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions

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Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B

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Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor

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Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6: e0147225

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