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Newsletter articlesFull Text
INTERNATIONAL PATENT: THE UNIVERSITY OF BRITISH COLUMBIA , INSTITUTE FOR BIOENGINEERING OF CATALONIA , CATALAN INSTITUTION FOR RESEARCH AND ADVANCED STUDIES , MIRAZIMI, ALI , IMBA-INSTITUT FUR MOLEKUL...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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ArticlesPeer ReviewedFull Text
Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients
Author / Creator:Stebbing, Justin ; Krishnan, Venkatesh ; de Bono, Stephanie ; Ottaviani, Silvia ; Casalini, Giacomo ; Richardson, Peter J ; Monteil, Vanessa ; Lauschke, Volker M ; Mirazimi, Ali ; Youhanna, Sonia ; Tan, Yee‐Joo ; Baldanti, Fausto ; Sarasini, Antonella ; Terres, Jorge A Ross ; Nickoloff, Brian J ; Higgs, Richard E ; Rocha, Guilherme ; Byers, Nicole L ; Schlichting, Douglas E ; Nirula, Ajay ; Cardoso, Anabela ; Corbellino, Mario
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2020-08, Vol.12 (8), p.e12697-n/a
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ArticlesPeer ReviewedFull Text
Mechanism of baricitinib supports artificial intelligence-predicted testing inCOVID-19 patients
Author / Creator:Stebbing, J ; Krishnan, V ; de, Bono S ; Ottaviani, S ; Casalini, G ; Richardson, PJ ; Monteil, V ; Lauschke, VM ; Mirazimi, A ; Youhanna, S
Journal title:EMBO molecular medicine, 2020-08, Vol.12 (8)
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ArticlesPeer ReviewedFull Text
ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology
Author / Creator:Gawish, Riem ; Starkl, Philipp ; Pimenov, Lisabeth ; Hladik, Anastasiya ; Lakovits, Karin ; Oberndorfer, Felicitas ; Cronin, Shane JF ; Ohradanova-Repic, Anna ; Wirnsberger, Gerald ; Agerer, Benedikt ; Endler, Lukas ; Capraz, Tümay ; Perthold, Jan W ; Cikes, Domagoj ; Koglgruber, Rubina ; Hagelkruys, Astrid ; Montserrat, Nuria ; Mirazimi, Ali ; Boon, Louis ; Stockinger, Hannes ; Bergthaler, Andreas ; Oostenbrink, Chris ; Penninger, Josef M ; Knapp, Sylvia
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2022-01, Vol.11
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ArticlesPeer ReviewedFull Text
Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
Author / Creator:Appelberg, Sofia ; Gupta, Soham ; Svensson Akusjärvi, Sara ; Ambikan, Anoop T. ; Mikaeloff, Flora ; Saccon, Elisa ; Végvári, Ákos ; Benfeitas, Rui ; Sperk, Maike ; Ståhlberg, Marie ; Krishnan, Shuba ; Singh, Kamal ; Penninger, Josef M. ; Mirazimi, Ali ; Neogi, Ujjwal
Publisher:United States: Taylor & Francis
Journal title:Emerging microbes & infections, 2020-01, Vol.9 (1), p.1748-1760
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ArticlesPeer ReviewedFull Text
A super-potent tetramerized ACE2 protein displays enhanced neutralization of SARS-CoV-2 virus infection
Author / Creator:Miller, Ami ; Leach, Adam ; Thomas, Jemima ; McAndrew, Craig ; Bentley, Emma ; Mattiuzzo, Giada ; John, Lijo ; Mirazimi, Ali ; Harris, Gemma ; Gamage, Nadisha ; Carr, Stephen ; Ali, Hanif ; Van Montfort, Rob ; Rabbitts, Terence
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-05, Vol.11 (1), p.10617-10617, Article 10617
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ArticlesPeer ReviewedFull Text
Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection
Author / Creator:Monteil, Vanessa ; Dyczynski, Matheus ; Lauschke, Volker M ; Kwon, Hyesoo ; Wirnsberger, Gerald ; Youhanna, Sonia ; Zhang, Haibo ; Slutsky, Arthur S ; Hurtado del Pozo, Carmen ; Horn, Moritz ; Montserrat, Nuria ; Penninger, Josef M ; Mirazimi, Ali
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2021-01, Vol.13 (1), p.e13426-n/a
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ArticlesPeer ReviewedFull Text
Bombali Virus in Mops condylurus Bat, Kenya
Author / Creator:Forbes, Kristian M. ; Webala, Paul W. ; Jääskeläinen, Anne J. ; Abdurahman, Samir ; Ogola, Joseph ; Masika, Moses M. ; Kivistö, Ilkka ; Alburkat, Hussein ; Plyusnin, Ilya ; Levanov, Lev ; Korhonen, Essi M. ; Huhtamo, Eili ; Mwaengo, Dufton ; Smura, Teemu ; Mirazimi, Ali ; Anzala, Omu ; Vapalahti, Olli ; Sironen, Tarja
Publisher:United States: U.S. National Center for Infectious Diseases
Journal title:Emerging infectious diseases, 2019-05, Vol.25 (5), p.955-957
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ArticlesPeer ReviewedFull Text
Methods of Inactivation of Highly Pathogenic Viruses for Molecular, Serology or Vaccine Development Purposes
Author / Creator:Elveborg, Simon ; Monteil, Vanessa ; Mirazimi, Ali
Publisher:Switzerland: MDPI AG
Journal title:Pathogens (Basel), 2022-02, Vol.11 (2), p.271
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ArticlesPeer ReviewedFull Text
Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level
Author / Creator:Zhu, Rong ; Canena, Daniel ; Sikora, Mateusz ; Klausberger, Miriam ; Seferovic, Hannah ; Mehdipour, Ahmad Reza ; Hain, Lisa ; Laurent, Elisabeth ; Monteil, Vanessa ; Wirnsberger, Gerald ; Wieneke, Ralph ; Tampé, Robert ; Kienzl, Nikolaus F. ; Mach, Lukas ; Mirazimi, Ali ; Oh, Yoo Jin ; Penninger, Josef M. ; Hummer, Gerhard ; Hinterdorfer, Peter
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-12, Vol.13 (1), p.7926-7926, Article 7926
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ArticlesPeer ReviewedFull Text
Taxonomy of the order Bunyavirales: second update 2018
Author / Creator:Maes, Piet ; Adkins, Scott ; Alkhovsky, Sergey V. ; Avšič-Županc, Tatjana ; Ballinger, Matthew J. ; Bente, Dennis A. ; Beer, Martin ; Bergeron, Éric ; Blair, Carol D. ; Briese, Thomas ; Buchmeier, Michael J. ; Burt, Felicity J. ; Calisher, Charles H. ; Charrel, Rémi N. ; Choi, Il Ryong ; Clegg, J. Christopher S. ; de la Torre, Juan Carlos ; de Lamballerie, Xavier ; DeRisi, Joseph L. ; Digiaro, Michele ; Drebot, Mike ; Ebihara, Hideki ; Elbeaino, Toufic ; Ergünay, Koray ; Fulhorst, Charles F. ; Garrison, Aura R. ; Gāo, George Fú ; Gonzalez, Jean-Paul J. ; Groschup, Martin H. ; Günther, Stephan ; Haenni, Anne-Lise ; Hall, Roy A. ; Hewson, Roger ; Hughes, Holly R. ; Jain, Rakesh K. ; Jonson, Miranda Gilda ; Junglen, Sandra ; Klempa, Boris ; Klingström, Jonas ; Kormelink, Richard ; Lambert, Amy J. ; Langevin, Stanley A. ; Lukashevich, Igor S. ; Marklewitz, Marco ; Martelli, Giovanni P. ; Mielke-Ehret, Nicole ; Mirazimi, Ali ; Mühlbach, Hans-Peter ; Naidu, Rayapati ; Nunes, Márcio Roberto Teixeira ; Palacios, Gustavo ; Papa, Anna ; Pawęska, Janusz T. ; Peters, Clarence J. ; Plyusnin, Alexander ; Radoshitzky, Sheli R. ; Resende, Renato O. ; Romanowski, Víctor ; Sall, Amadou Alpha ; Salvato, Maria S. ; Sasaya, Takahide ; Schmaljohn, Connie ; Shí, Xiǎohóng ; Shirako, Yukio ; Simmonds, Peter ; Sironi, Manuela ; Song, Jin-Won ; Spengler, Jessica R. ; Stenglein, Mark D. ; Tesh, Robert B. ; Turina, Massimo ; Wèi, Tàiyún ; Whitfield, Anna E. ; Yeh, Shyi-Dong ; Zerbini, F. Murilo ; Zhang, Yong-Zhen ; Zhou, Xueping ; Kuhn, Jens H.
Publisher:Vienna: Springer Vienna
Journal title:ARCHIVES OF VIROLOGY, 2019-03, Vol.164 (3), p.927-941
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ArticlesPeer ReviewedFull Text
Hazara virus and Crimean-Congo Hemorrhagic Fever Virus show a different pattern of entry in fully-polarized Caco-2 cell line
Author / Creator:Monteil, Vanessa ; Salata, Cristiano ; Appelberg, Sofia ; Mirazimi, Ali
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2020-11, Vol.14 (11), p.e0008863-e0008863
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ArticlesPeer ReviewedFull Text
Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse
Author / Creator:Flaxman, Amy ; Sebastian, Sarah ; Appelberg, Sofia ; Cha, Kuan M. ; Ulaszewska, Marta ; Purushotham, Jyothi ; Gilbride, Ciaran ; Sharpe, Hannah ; Spencer, Alexandra J. ; Bibi, Sagida ; Wright, Daniel ; Schmidt, Isabel ; Dowall, Stuart ; Easterbrook, Linda ; Findlay-Wilson, Stephen ; Gilbert, Sarah ; Mirazimi, Ali ; Lambe, Teresa
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-06, Vol.20 (6), p.e1012262
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ArticlesPeer ReviewedFull Text
ISG15 overexpression compensates the defect of Crimean-Congo hemorrhagic fever virus polymerase bearing a protease-inactive ovarian tumor domain
Author / Creator:Devignot, Stephanie ; Kromer, Thilo ; Mirazimi, Ali ; Weber, Friedemann
Publisher:San Francisco: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2020-09, Vol.14 (9), p.e0008610-e0008610
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ArticlesPeer ReviewedFull Text
Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections
Author / Creator:Monteil, Vanessa ; Kwon, Hyesoo ; John, Lijo ; Salata, Cristiano ; Jonsson, Gustav ; Vorrink, Sabine U. ; Appelberg, Sofia ; Youhanna, Sonia ; Dyczynski, Matheus ; Leopoldi, Alexandra ; Leeb, Nicole ; Volz, Jennifer ; Hagelkruys, Astrid ; Kellner, Max J. ; Devignot, Stéphanie ; Michlits, Georg ; Foong-Sobis, Michelle ; Weber, Friedemann ; Lauschke, Volker M. ; Horn, Moritz ; Feldmann, Heinz ; Elling, Ulrich ; Penninger, Josef M. ; Mirazimi, Ali
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-10, Vol.14 (1), p.6785-16, Article 6785
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ArticlesPeer ReviewedFull Text
Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction
Author / Creator:Habjan, Matthias ; Andersson, Ida ; Klingström, Jonas ; Schümann, Michael ; Martin, Arnold ; Zimmermann, Petra ; Wagner, Valentina ; Pichlmair, Andreas ; Schneider, Urs ; Mühlberger, Elke ; Mirazimi, Ali ; Weber, Friedemann
Publisher:United States: Public Library of Science
Journal title:PloS one, 2008-04, Vol.3 (4), p.e2032-e2032
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ArticlesPeer ReviewedFull Text
Type-I interferon signatures in SARS-CoV-2 infected Huh7 cells
Author / Creator:Chen, Xi ; Saccon, Elisa ; Appelberg, K. Sofia ; Mikaeloff, Flora ; Rodriguez, Jimmy Esneider ; Vinhas, Beatriz Sá ; Frisan, Teresa ; Végvári, Ákos ; Mirazimi, Ali ; Neogi, Ujjwal ; Gupta, Soham
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2021-05, Vol.7 (1), p.114-114, Article 114
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ArticlesPeer ReviewedFull Text
Author Correction: Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level
Author / Creator:Zhu, Rong ; Canena, Daniel ; Sikora, Mateusz ; Klausberger, Miriam ; Seferovic, Hannah ; Mehdipour, Ahmad Reza ; Hain, Lisa ; Laurent, Elisabeth ; Monteil, Vanessa ; Wirnsberger, Gerald ; Wieneke, Ralph ; Tampé, Robert ; Kienzl, Nikolaus F. ; Mach, Lukas ; Mirazimi, Ali ; Oh, Yoo Jin ; Penninger, Josef M. ; Hummer, Gerhard ; Hinterdorfer, Peter
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-02, Vol.14 (1), p.1142-1142, Article 1142
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ArticlesPeer ReviewedFull Text
A DNA-based vaccine protects against Crimean-Congo haemorrhagic fever virus disease in a Cynomolgus macaque model
Author / Creator:Hawman, David W. ; Ahlén, Gustaf ; Appelberg, K. Sofia ; Meade-White, Kimberly ; Hanley, Patrick W. ; Scott, Dana ; Monteil, Vanessa ; Devignot, Stephanie ; Okumura, Atsushi ; Weber, Friedemann ; Feldmann, Heinz ; Sällberg, Matti ; Mirazimi, Ali
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2021-02, Vol.6 (2), p.187-195
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ArticlesPeer ReviewedFull Text
Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target
Author / Creator:Neogi, Ujjwal ; Elaldi, Nazif ; Appelberg, Sofia ; Ambikan, Anoop ; Kennedy, Emma ; Dowall, Stuart ; Bagci, Binnur K ; Gupta, Soham ; Rodriguez, Jimmy E ; Svensson-Akusjärvi, Sara ; Monteil, Vanessa ; Vegvari, Akos ; Benfeitas, Rui ; Banerjea, Akhil ; Weber, Friedemann ; Hewson, Roger ; Mirazimi, Ali
Publisher:England: eLife Sciences Publications, Ltd
Journal title:eLife, 2022-04, Vol.11
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INTERNATIONAL PATENT: THE UNIVERSITY OF BRITISH COLUMBIA , INSTITUTE FOR BIOENGINEERING OF CATALONIA , CATALAN INSTITUTION FOR RESEARCH AND ADVANCED STUDIES , MIRAZIMI, ALI , IMBA-INSTITUT FUR MOLEKUL...

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Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients

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Mechanism of baricitinib supports artificial intelligence-predicted testing inCOVID-19 patients

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ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

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Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells

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A super-potent tetramerized ACE2 protein displays enhanced neutralization of SARS-CoV-2 virus infection

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Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection

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Bombali Virus in Mops condylurus Bat, Kenya

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Methods of Inactivation of Highly Pathogenic Viruses for Molecular, Serology or Vaccine Development Purposes

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Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level

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Taxonomy of the order Bunyavirales: second update 2018

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Hazara virus and Crimean-Congo Hemorrhagic Fever Virus show a different pattern of entry in fully-polarized Caco-2 cell line

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Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse

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ISG15 overexpression compensates the defect of Crimean-Congo hemorrhagic fever virus polymerase bearing a protease-inactive ovarian tumor domain

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Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections

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Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

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Type-I interferon signatures in SARS-CoV-2 infected Huh7 cells

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Author Correction: Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level

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A DNA-based vaccine protects against Crimean-Congo haemorrhagic fever virus disease in a Cynomolgus macaque model

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Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target

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