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Newsletter articlesFull Text
INTERNATIONAL PATENT: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, MIYAKE, KOICHI FILES APPLICATION FOR "METHODS AND COMPOSITIONS FOR TREATING HYPOPHOSPHATASIA"
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2022
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ArticlesPeer ReviewedFull Text
Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration
Author / Creator:Yamaguchi, Hirofumi ; Honda, Shinya ; Torii, Satoru ; Shimizu, Kimiko ; Katoh, Kaoru ; Miyake, Koichi ; Miyake, Noriko ; Fujikake, Nobuhiro ; Sakurai, Hajime Tajima ; Arakawa, Satoko ; Shimizu, Shigeomi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-10, Vol.11 (1), p.5311-5311, Article 5311
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ArticlesPeer ReviewedFull Text
Treatment of adult metachromatic leukodystrophy model mice using intrathecal administration of type 9 AAV vector encoding arylsulfatase A
Author / Creator:Miyake, Noriko ; Miyake, Koichi ; Sakai, Atsushi ; Yamamoto, Motoko ; Suzuki, Hidenori ; Shimada, Takashi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-10, Vol.11 (1), p.20513-20513, Article 20513
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ArticlesPeer ReviewedFull Text
MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain
Author / Creator:Sakai, Atsushi ; Saitow, Fumihito ; Maruyama, Motoyo ; Miyake, Noriko ; Miyake, Koichi ; Shimada, Takashi ; Okada, Takashi ; Suzuki, Hidenori
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-07, Vol.8 (1), p.16079-16079, Article 16079
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ArticlesPeer ReviewedFull Text
Improved Intravitreal AAV-Mediated Inner Retinal Gene Transduction after Surgical Internal Limiting Membrane Peeling in Cynomolgus Monkeys
Author / Creator:Takahashi, Kazuhisa ; Igarashi, Tsutomu ; Miyake, Koichi ; Kobayashi, Maika ; Yaguchi, Chiemi ; Iijima, Osamu ; Yamazaki, Yoshiyuki ; Katakai, Yuko ; Miyake, Noriko ; Kameya, Shuhei ; Shimada, Takashi ; Takahashi, Hiroshi ; Okada, Takashi
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2017-01, Vol.25 (1), p.296-302
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Newsletter articlesFull Text
WIPO PUBLISHES PATENT OF KUNIHIKO HIKIRI, NORIAKI MIYAKE, KOICHI ITANI AND VOLVO LASTVAGNAR AKTIEBOLAG FOR "CHARGE/DISCHARGE SYSTEM" (JAPANESE INVENTORS)
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2014
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ArticlesPeer ReviewedFull Text
siRNA Knockdown of Tissue Inhibitor of Metalloproteinase-1 in Keloid Fibroblasts Leads to Degradation of Collagen Type I
Author / Creator:Aoki, Masayo ; Miyake, Koichi ; Ogawa, Rei ; Dohi, Teruyuki ; Akaishi, Satoshi ; Hyakusoku, Hiko ; Shimada, Takashi
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2014-03, Vol.134 (3), p.818-826
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ArticlesPeer ReviewedFull Text
DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing
Author / Creator:Nishina, Kazutaka ; Piao, Wenying ; Yoshida-Tanaka, Kie ; Sujino, Yumiko ; Nishina, Tomoko ; Yamamoto, Tsuyoshi ; Nitta, Keiko ; Yoshioka, Kotaro ; Kuwahara, Hiroya ; Yasuhara, Hidenori ; Baba, Takeshi ; Ono, Fumiko ; Miyata, Kanjiro ; Miyake, Koichi ; Seth, Punit P. ; Low, Audrey ; Yoshida, Masayuki ; Bennett, C. Frank ; Kataoka, Kazunori ; Mizusawa, Hidehiro ; Obika, Satoshi ; Yokota, Takanori
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-08, Vol.6 (1), p.7969, Article 7969
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ArticlesPeer ReviewedFull Text
Enzyme replacement in the CSF to treat metachromatic leukodystrophy in mouse model using single intracerebroventricular injection of self-complementary AAV1 vector
Author / Creator:Hironaka, Kohei ; Yamazaki, Yoshiyuki ; Hirai, Yukihiko ; Yamamoto, Motoko ; Miyake, Noriko ; Miyake, Koichi ; Okada, Takashi ; Morita, Akio ; Shimada, Takashi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-08, Vol.5 (1), p.13104-13104, Article 13104
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ArticlesPeer ReviewedFull Text
160. Successful Treatment of Neonatal Metachromatic Leukodystrophy Model Mice by Low Dose of Self-Complementary AAV Type9 Vector Expressing ASA
Author / Creator:Miyake, Noriko ; Miyake, Koichi ; Yamamoto, Motoko ; Shimada, Takashi ; Okada, Takashi
Publisher:Elsevier Inc
Journal title:Molecular therapy, 2016-05, Vol.24, p.S63-S63
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ArticlesPeer ReviewedFull Text
Parkin-Mediated Protection of Dopaminergic Neurons in a Chronic MPTP-Minipump Mouse Model of Parkinson Disease
Author / Creator:Yasuda, Toru ; Hayakawa, Hideki ; Nihira, Tomoko ; Ren, Yong-Ri ; Nakata, Yasuto ; Nagai, Makiko ; Hattori, Nobutaka ; Miyake, Koichi ; Takada, Masahiko ; Shimada, Takashi ; Mizuno, Yoshikuni ; Mochizuki, Hideki
Publisher:Hagerstown, MD: American Association of Neuropathologists, Inc
Journal title:Journal of neuropathology and experimental neurology, 2011-08, Vol.70 (8), p.686-697
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ArticlesPeer ReviewedFull Text
Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAP‐D10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia
Author / Creator:Amadeu de Oliveira, Flavia ; Mohamed, Fatma F. ; Kinoshita, Yuka ; Narisawa, Sonoko ; Farquharson, Colin ; Miyake, Koichi ; Foster, Brian L ; Millan, Jose Luis
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:JBMR plus, 2023-01, Vol.7 (1), p.e10709-n/a
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Newsletter articlesFull Text
HIV/AIDS Gene Therapy; Recombinant HIV vector effective
Publisher:Atlanta: NewsRx
Journal title:AIDS Weekly, 2003, p.1
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ArticlesPeer ReviewedFull Text
Adeno-Associated Vector (Type 8)-Mediated Expression of Soluble Flt-1 Efficiently Inhibits Neovascularization in a Murine Choroidal Neovascularization Model
Author / Creator:IGARASHI, Tsutomu ; MIYAKE, Koichi ; MASUDA, Ikuya ; TAKAHASHI, Hiroshi ; SHIMADA, Takashi
Publisher:Larchmont, NY: Liebert
Journal title:Human gene therapy, 2010-05, Vol.21 (5), p.631-637
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ArticlesPeer ReviewedFull Text
Circadian disruption accelerates tumor growth and angio/stromagenesis through a Wnt signaling pathway
Author / Creator:Yasuniwa, Yoshihiro ; Izumi, Hiroto ; Wang, Ke-Yong ; Shimajiri, Shohei ; Sasaguri, Yasuyuki ; Kawai, Kazuaki ; Kasai, Hiroshi ; Shimada, Takashi ; Miyake, Koichi ; Kashiwagi, Eiji ; Hirano, Gen ; Kidani, Akihiko ; Akiyama, Masaki ; Han, Bin ; Wu, Ying ; Ieiri, Ichiro ; Higuchi, Shun ; Kohno, Kimitoshi
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-12, Vol.5 (12), p.e15330
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ArticlesPeer ReviewedFull Text
Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model
Author / Creator:Huda, Fathul ; Konno, Ayumu ; Matsuzaki, Yasunori ; Goenawan, Hanna ; Miyake, Koichi ; Shimada, Takashi ; Hirai, Hirokazu
Publisher:United States: Elsevier Limited
Journal title:Molecular therapy. Methods & clinical development, 2014-01, Vol.1 (C), p.14032-14032, Article 14032
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ArticlesPeer ReviewedFull Text
Successful Treatment of Metachromatic Leukodystrophy Using Bone Marrow Transplantation of HoxB4 Overexpressing Cells
Author / Creator:Miyake, Noriko ; Miyake, Koichi ; Karlsson, Stefan ; Shimada, Takashi
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2010-07, Vol.18 (7), p.1373-1378
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ArticlesPeer ReviewedFull Text
Role of survivin in acute lung injury: epithelial cells of mice and humans
Author / Creator:Terasaki, Yasuhiro ; Terasaki, Mika ; Urushiyama, Hirokazu ; Nagasaka, Shinya ; Takahashi, Mikiko ; Kunugi, Shinobu ; Ishikawa, Arimi ; Wakamatsu, Kyoko ; Kuwahara, Naomi ; Miyake, Koichi ; Fukuda, Yuh
Publisher:New York: Nature Publishing Group US
Journal title:Laboratory investigation, 2013-10, Vol.93 (10), p.1147-1163
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ArticlesPeer ReviewedFull Text
Lentivirus-mediated expression of angiostatin efficiently inhibits neovascularization in a murine proliferative retinopathy model
Author / Creator:Igarashi, Tsutomu ; Miyake, Koichi ; Kato, Ko ; Watanabe, Atsushi ; Ishizaki, Masamichi ; Ohara, Kunitoshi ; Shimada, Takashi
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2003-02, Vol.10 (3), p.219-226
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ArticlesPeer ReviewedFull Text
Treatment of hypophosphatasia by muscle-directed expression of bone-targeted alkaline phosphatase via self-complementary AAV8 vector
Author / Creator:Nakamura-Takahashi, Aki ; Miyake, Koichi ; Watanabe, Atsushi ; Hirai, Yukihiko ; Iijima, Osamu ; Miyake, Noriko ; Adachi, Kumi ; Nitahara-Kasahara, Yuko ; Kinoshita, Hideaki ; Noguchi, Taku ; Abe, Shinichi ; Narisawa, Sonoko ; Millán, Jose Luis ; Shimada, Takashi ; Okada, Takashi
Publisher:United States: Elsevier Limited
Journal title:Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.15059-15059, Article 15059
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INTERNATIONAL PATENT: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, MIYAKE, KOICHI FILES APPLICATION FOR "METHODS AND COMPOSITIONS FOR TREATING HYPOPHOSPHATASIA"

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Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration

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Treatment of adult metachromatic leukodystrophy model mice using intrathecal administration of type 9 AAV vector encoding arylsulfatase A

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MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain

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Improved Intravitreal AAV-Mediated Inner Retinal Gene Transduction after Surgical Internal Limiting Membrane Peeling in Cynomolgus Monkeys

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WIPO PUBLISHES PATENT OF KUNIHIKO HIKIRI, NORIAKI MIYAKE, KOICHI ITANI AND VOLVO LASTVAGNAR AKTIEBOLAG FOR "CHARGE/DISCHARGE SYSTEM" (JAPANESE INVENTORS)

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siRNA Knockdown of Tissue Inhibitor of Metalloproteinase-1 in Keloid Fibroblasts Leads to Degradation of Collagen Type I

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DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing

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Enzyme replacement in the CSF to treat metachromatic leukodystrophy in mouse model using single intracerebroventricular injection of self-complementary AAV1 vector

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160. Successful Treatment of Neonatal Metachromatic Leukodystrophy Model Mice by Low Dose of Self-Complementary AAV Type9 Vector Expressing ASA

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Parkin-Mediated Protection of Dopaminergic Neurons in a Chronic MPTP-Minipump Mouse Model of Parkinson Disease

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Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAP‐D10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia

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HIV/AIDS Gene Therapy; Recombinant HIV vector effective

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Adeno-Associated Vector (Type 8)-Mediated Expression of Soluble Flt-1 Efficiently Inhibits Neovascularization in a Murine Choroidal Neovascularization Model

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Circadian disruption accelerates tumor growth and angio/stromagenesis through a Wnt signaling pathway

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Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model

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Successful Treatment of Metachromatic Leukodystrophy Using Bone Marrow Transplantation of HoxB4 Overexpressing Cells

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Role of survivin in acute lung injury: epithelial cells of mice and humans

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Lentivirus-mediated expression of angiostatin efficiently inhibits neovascularization in a murine proliferative retinopathy model

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Treatment of hypophosphatasia by muscle-directed expression of bone-targeted alkaline phosphatase via self-complementary AAV8 vector

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