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ArticlesPeer ReviewedFull Text
The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response
Author / Creator:Seifert, Leon Louis ; Si, Clara ; Saha, Debjani ; Sadic, Mohammad ; de Vries, Maren ; Ballentine, Sarah ; Briley, Aaron ; Wang, Guojun ; Valero-Jimenez, Ana M. ; Mohamed, Adil ; Schaefer, Uwe ; Moulton, Hong M. ; García-Sastre, Adolfo ; Tripathi, Shashank ; Rosenberg, Brad R. ; Dittmann, Meike
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2019-11, Vol.15 (11), p.e1007634
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Development of DG9 peptide-conjugated single- and multi-exon skipping therapies for the treatment of Duchenne muscular dystrophy
Author / Creator:Lim, Kenji Rowel Q. ; Woo, Stanley ; Melo, Dyanna ; Huang, Yiqing ; Dzierlega, Kasia ; Shah, Md Nur Ahad ; Aslesh, Tejal ; Roshmi, Rohini Roy ; Echigoya, Yusuke ; Maruyama, Rika ; Moulton, Hong M. ; Yokota, Toshifumi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (9), p.1-7
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DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function
Author / Creator:Shah, Md Nur Ahad ; Wilton-Clark, Harry ; Haque, Farhia ; Powell, Brooklynn ; Sutanto, Laura Edellein ; Maradiya, Radha ; Zhabyeyev, Pavel ; Roshmi, Rohini Roy ; Anwar, Saeed ; Aslesh, Tejal ; Lim, Kenji Rowel Q. ; Maruyama, Rika ; Bigot, Anne ; Young, Courtney S. ; Bittner, Scott ; Spencer, Melissa J. ; Moulton, Hong M. ; Oudit, Gavin Y. ; Yokota, Toshifumi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-05, Vol.16 (1), p.4477-16, Article 4477
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Sustained Dystrophin Expression Induced by Peptide-conjugated Morpholino Oligomers in the Muscles of mdx Mice
Author / Creator:Jearawiriyapaisarn, Natee ; Moulton, Hong M ; Buckley, Brian ; Roberts, Jennifer ; Sazani, Peter ; Fucharoen, Suthat ; Iversen, Patrick L ; Kole, Ryszard
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2008-09, Vol.16 (9), p.1624-1629
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Unveiling the Role of TMPRSS2 in the Proteolytic Activation of Pandemic and Zoonotic Influenza Viruses and Coronaviruses in Human Airway Cells
Author / Creator:Schwerdtner, Marie ; Schmacke, Luna C. ; Nave, Julia ; Limburg, Hannah ; Steinmetzer, Torsten ; Stein, David A. ; Moulton, Hong M. ; Böttcher-Friebertshäuser, Eva
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2024-11, Vol.16 (11), p.1798
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Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer
Author / Creator:Wu, Bo ; Moulton, Hong M ; Iversen, Patrick L ; Jiang, Jiangang ; Li, Juan ; Li, Jianbin ; Spurney, Christopher F ; Sali, Arpana ; Guerron, Alfredo D ; Nagaraju, Kanneboyina ; Doran, Timothy ; Lu, Peijuan ; Xiao, Xiao ; Lu, Qi Long
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (39), p.14814-14819
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A Dystrophin Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping
Author / Creator:Echigoya, Yusuke ; Trieu, Nhu ; Duddy, William ; Moulton, Hong M. ; Yin, HaiFang ; Partridge, Terence A. ; Hoffman, Eric P. ; Kornegay, Joe N. ; Rohret, Frank A. ; Rogers, Christopher S. ; Yokota, Toshifumi
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-12, Vol.22 (23), p.13065
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Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide–Morpholino Conjugate in Dystrophin-Deficient mdx Mice
Author / Creator:Gao, Xianjun ; Zhao, Jingwen ; Han, Gang ; Zhang, Yajie ; Dong, Xue ; Cao, Limin ; Wang, Qingsong ; Moulton, Hong M ; Yin, HaiFang
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2014-07, Vol.22 (7), p.1333-1341
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MOTS‐c promotes phosphorodiamidate morpholino oligomer uptake and efficacy in dystrophic mice
Author / Creator:Ran, Ning ; Lin, Caorui ; Leng, Ling ; Han, Gang ; Geng, Mengyuan ; Wu, Yingjie ; Bittner, Scott ; Moulton, Hong M ; Yin, HaiFang
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2021-02, Vol.13 (2), p.e12993-n/a
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Functional Rescue of Dystrophin-deficient mdx Mice by a Chimeric Peptide-PMO
Author / Creator:Yin, HaiFang ; Moulton, Hong M ; Betts, Corinne ; Merritt, Thomas ; Seow, Yiqi ; Ashraf, Shirin ; Wang, QingSong ; Boutilier, Jordan ; Wood, Matthew JA
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2010-10, Vol.18 (10), p.1822-1829
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Effect of Combined Systemic and Local Morpholino Treatment on the Spinal Muscular Atrophy Δ7 Mouse Model Phenotype
Author / Creator:Nizzardo, Monica, PhD ; Simone, Chiara, PhD ; Salani, Sabrina, PhD ; Ruepp, Marc-David, PhD ; Rizzo, Federica, PhD ; Ruggieri, Margherita, PhD ; Zanetta, Chiara, MD ; Brajkovic, Simona, MD ; Moulton, Hong M., PhD ; Müehlemann, Oliver, PhD ; Bresolin, Nereo, MD ; Comi, Giacomo P., MD ; Corti, Stefania, MD, PhD
Publisher:Bridgewater, NJ: Elsevier Inc
Journal title:Clinical therapeutics, 2014-03, Vol.36 (3), p.340-356.e5
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RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice
Author / Creator:Svasti, Saovaros ; Suwanmanee, Thipparat ; Fucharoen, Suthat ; Moulton, Hong M ; Nelson, Michelle H ; Maeda, Nobuyo ; Smithies, Oliver ; Kole, Ryszard
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-01, Vol.106 (4), p.1205-1210
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Fructose Promotes Uptake and Activity of Oligonucleotides With Different Chemistries in a Context-dependent Manner in mdx Mice
Author / Creator:Cao, Limin ; Han, Gang ; Lin, Caorui ; Gu, Ben ; Gao, Xianjun ; Moulton, Hong M ; Seow, Yiqi ; Yin, HaiFang
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2016, Vol.5 (6), p.e329-e329, Article e329
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Dystrophin Isoform Induction In Vivo by Antisense-mediated Alternative Splicing
Author / Creator:Fletcher, Sue ; Adams, Abbie M ; Johnsen, Russell D ; Greer, Kane ; Moulton, Hong M ; Wilton, Steve D
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2010-06, Vol.18 (6), p.1218-1223
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Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy
Author / Creator:Echigoya, Yusuke ; Nakamura, Akinori ; Nagata, Tetsuya ; Urasawa, Nobuyuki ; Lim, Kenji Rowel Q. ; Trieu, Nhu ; Panesar, Dharminder ; Kuraoka, Mutsuki ; Moulton, Hong M. ; Saito, Takashi ; Aoki, Yoshitsugu ; Iversen, Patrick ; Sazani, Peter ; Kole, Ryszard ; Maruyama, Rika ; Partridge, Terry ; Takeda, Shin’ichi ; Yokota, Toshifumi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (16), p.4213-4218
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Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency
Author / Creator:Yin, HaiFang ; Boisguerin, Prisca ; Moulton, Hong M ; Betts, Corinne ; Seow, Yiqi ; Boutilier, Jordan ; Wang, Qingsong ; Walsh, Anthony ; Lebleu, Bernard ; Wood, Matthew JA
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2013, Vol.2 (9), p.e124-e124, Article e124
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Effect of Combined Systemic and Local Morpholino Treatment on the Spinal Muscular Atrophy Delta 7 Mouse Model Phenotype
Author / Creator:Nizzardo, Monica ; Simone, Chiara ; Salani, Sabrina ; Ruepp, Marc-David ; Rizzo, Federica ; Ruggieri, Margherita ; Zanetta, Chiara ; Brajkovic, Simona ; Moulton, Hong M ; Mueehlemann, Oliver ; Bresolin, Nereo ; Comi, Giacomo P ; Corti, Stefania
Journal title:Clinical therapeutics, 2014-03, Vol.36 (3), p.340-356.e5
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Hexose Potentiates Peptide-Conjugated Morpholino Oligomer Efficacy in Cardiac Muscles of Dystrophic Mice in an Age-Dependent Manner
Author / Creator:Han, Gang ; Gu, Ben ; Lin, Caorui ; Ning, Hanhan ; Song, Jun ; Gao, Xianjun ; Moulton, Hong M. ; Yin, HaiFang
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2019-12, Vol.18, p.341-350
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Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy
Author / Creator:Martin-Sancho, Laura ; Tripathi, Shashank ; Rodriguez-Frandsen, Ariel ; Pache, Lars ; Sanchez-Aparicio, Maite ; McGregor, Michael J. ; Haas, Kelsey M. ; Swaney, Danielle L. ; Nguyen, Thong T. ; Mamede, João I. ; Churas, Christopher ; Pratt, Dexter ; Rosenthal, Sara B. ; Riva, Laura ; Nguyen, Courtney ; Beltran-Raygoza, Nish ; Soonthornvacharin, Stephen ; Wang, Guojun ; Jimenez-Morales, David ; De Jesus, Paul D. ; Moulton, Hong M. ; Stein, David A. ; Chang, Max W. ; Benner, Chris ; Ideker, Trey ; Albrecht, Randy A. ; Hultquist, Judd F. ; Krogan, Nevan J. ; García-Sastre, Adolfo ; Chanda, Sumit K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2021-10, Vol.6 (10), p.1319-1333
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Morpholino Oligomer–Mediated Exon Skipping Averts the Onset of Dystrophic Pathology in the mdx Mouse
Author / Creator:Fletcher, Sue ; Honeyman, Kaite ; Fall, Abbie M ; Harding, Penny L ; Johnsen, Russell D ; Steinhaus, Joshua P ; Moulton, Hong M ; Iversen, Patrick L ; Wilton, Stephen D
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2007-09, Vol.15 (9), p.1587-1592
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Showing 1 to 20 of 23 results

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The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response

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Development of DG9 peptide-conjugated single- and multi-exon skipping therapies for the treatment of Duchenne muscular dystrophy

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DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function

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Sustained Dystrophin Expression Induced by Peptide-conjugated Morpholino Oligomers in the Muscles of mdx Mice

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Unveiling the Role of TMPRSS2 in the Proteolytic Activation of Pandemic and Zoonotic Influenza Viruses and Coronaviruses in Human Airway Cells

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Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

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A Dystrophin Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping

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Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide–Morpholino Conjugate in Dystrophin-Deficient mdx Mice

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MOTS‐c promotes phosphorodiamidate morpholino oligomer uptake and efficacy in dystrophic mice

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Functional Rescue of Dystrophin-deficient mdx Mice by a Chimeric Peptide-PMO

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Effect of Combined Systemic and Local Morpholino Treatment on the Spinal Muscular Atrophy Δ7 Mouse Model Phenotype

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RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice

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Fructose Promotes Uptake and Activity of Oligonucleotides With Different Chemistries in a Context-dependent Manner in mdx Mice

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Dystrophin Isoform Induction In Vivo by Antisense-mediated Alternative Splicing

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Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy

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Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency

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Effect of Combined Systemic and Local Morpholino Treatment on the Spinal Muscular Atrophy Delta 7 Mouse Model Phenotype

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Hexose Potentiates Peptide-Conjugated Morpholino Oligomer Efficacy in Cardiac Muscles of Dystrophic Mice in an Age-Dependent Manner

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Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy

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Morpholino Oligomer–Mediated Exon Skipping Averts the Onset of Dystrophic Pathology in the mdx Mouse

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