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ArticlesPeer ReviewedFull Text
Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis
Author / Creator:Kraus, William E ; Muoio, Deborah M ; Stevens, Robert ; Craig, Damian ; Bain, James R ; Grass, Elizabeth ; Haynes, Carol ; Kwee, Lydia ; Qin, Xuejun ; Slentz, Dorothy H ; Krupp, Deidre ; Muehlbauer, Michael ; Hauser, Elizabeth R ; Gregory, Simon G ; Newgard, Christopher B ; Shah, Svati H
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-11, Vol.11 (11), p.e1005553-e1005553
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Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption
Author / Creator:USSHER, John R ; KOVES, Timothy R ; LOPASCHUK, Gary D ; CADETE, Virgilio J. J ; LIYAN ZHANG ; JASWAL, Jagdip S ; SWYRD, Suzanne J ; LOPASCHUK, David G ; PROCTOR, Spencer D ; KEUNG, Wendy ; MUOIO, Deborah M
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2010-10, Vol.59 (10), p.2453-2464
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Molecular alterations in skeletal muscle in rheumatoid arthritis are related to disease activity, physical inactivity, and disability
Author / Creator:Huffman, Kim M ; Jessee, Ryan ; Andonian, Brian ; Davis, Brittany N ; Narowski, Rachel ; Huebner, Janet L ; Kraus, Virginia B ; McCracken, Julie ; Gilmore, Brian F ; Tune, K Noelle ; Campbell, Milton ; Koves, Timothy R ; Muoio, Deborah M ; Hubal, Monica J ; Kraus, William E
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2017-01, Vol.19 (1), p.12-12, Article 12
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Glucose sensing by MondoA:Mlx complexes: A role for hexokinases and direct regulation of thioredoxin-interacting protein expression
Author / Creator:Stoltzman, Carrie A ; Peterson, Christopher W ; Breen, Kevin T ; Muoio, Deborah M ; Billin, Andrew N ; Ayer, Donald E
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (19), p.6912-6917
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RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure
Author / Creator:Yamamoto, Tsunehisa ; Maurya, Santosh K ; Pruzinsky, Elizabeth ; Batmanov, Kirill ; Xiao, Yang ; Sulon, Sarah M ; Sakamoto, Tomoya ; Wang, Yang ; Lai, Ling ; McDaid, Kendra S ; Shewale, Swapnil V ; Leone, Teresa C ; Koves, Timothy R ; Muoio, Deborah M ; Dierickx, Pieterjan ; Lazar, Mitchell A ; Lewandowski, E Douglas ; Kelly, Daniel P
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2023-05, Vol.133 (9), p.1-16
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A Lipidomics Analysis of the Relationship Between Dietary Fatty Acid Composition and Insulin Sensitivity in Young Adults
Author / Creator:LAWRENCE KIEN, C ; BUNN, Janice Y ; MUOIO, Deborah M ; POYNTER, Matthew E ; STEVENS, Robert ; BAIN, James ; IKAYEVA, Olga ; FUKAGAWA, Naomi K ; CHAMPAGNE, Catherine M ; CRAIN, Karen I ; KOVES, Timothy R
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2013-04, Vol.62 (4), p.1054-1063
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Rheumatoid arthritis T cell and muscle oxidative metabolism associate with exercise-induced changes in cardiorespiratory fitness
Author / Creator:Andonian, Brian J. ; Koss, Alec ; Koves, Timothy R. ; Hauser, Elizabeth R. ; Hubal, Monica J. ; Pober, David M. ; Lord, Janet M. ; MacIver, Nancie J. ; St Clair, E. William ; Muoio, Deborah M. ; Kraus, William E. ; Bartlett, David B. ; Huffman, Kim M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-05, Vol.12 (1), p.7450-13, Article 7450
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Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA
Author / Creator:Chen, Julia Ling-Yu ; Merl, Daniel ; Peterson, Christopher W ; Wu, Jianli ; Liu, Patrick Yantyng ; Yin, Hanwei ; Muoio, Deborah M ; Ayer, Don E ; West, Mike ; Chi, Jen-Tsan
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2010-09, Vol.6 (9), p.e1001093-e1001093
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Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection
Author / Creator:Lindeboom, Lucas ; Nabuurs, Christine I ; Hoeks, Joris ; Brouwers, Bram ; Phielix, Esther ; Kooi, M Eline ; Hesselink, Matthijs K C ; Wildberger, Joachim E ; Stevens, Robert D ; Koves, Timothy ; Muoio, Deborah M ; Schrauwen, Patrick ; Schrauwen-Hinderling, Vera B
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2014-11, Vol.124 (11), p.4915-4925
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ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate
Author / Creator:Keenan, Melissa M ; Liu, Beiyu ; Tang, Xiaohu ; Wu, Jianli ; Cyr, Derek ; Stevens, Robert D ; Ilkayeva, Olga ; Huang, Zhiqing ; Tollini, Laura A ; Murphy, Susan K ; Lucas, Joseph ; Muoio, Deborah M ; Kim, So Young ; Chi, Jen-Tsan
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-10, Vol.11 (10), p.e1005599
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ArticlesPeer ReviewedFull Text
Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase
Author / Creator:USSHER, John R ; KOVES, Timothy R ; JASWAL, Jagdip S ; LIYAN ZHANG ; ILKAYEVA, Olga ; DYCK, Jason R. B ; MUOIO, Deborah M ; LOPASCHUK, Gary D
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2009-08, Vol.58 (8), p.1766-1775
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ArticlesPeer ReviewedFull Text
Metabolism and Vascular Fatty Acid Transport
Author / Creator:Muoio, Deborah M
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2010-07, Vol.363 (3), p.291-293
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Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
Author / Creator:Muoio, Deborah M. ; Newgard, Christopher B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2008-03, Vol.9 (3), p.193-205
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Peroxisome Proliferator-Activated Receptor-α Regulates Fatty Acid Utilization in Primary Human Skeletal Muscle Cells
Author / Creator:MUOIO, Deborah M ; WAY, James M ; TANNER, Charles J ; WINEGAR, Deborah A ; KLIEWER, Steven A ; HOUMARD, Joseph A ; KRAUS, William E ; DOHM, G. Lynis
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2002-04, Vol.51 (4), p.901-909
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Physiological and nutritional regulation of enzymes of triacylglycerol synthesis
Author / Creator:COLEMAN, R. A ; LEWIN, T. M ; MUOIO, D. M
Publisher:Palo Alto, CA: Annual Reviews
Journal title:Annual review of nutrition, 2000-01, Vol.20 (1), p.77-103
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HDAC3 sets the timer on muscle fuel switching
Author / Creator:Muoio, Deborah M
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2017-02, Vol.23 (2), p.148-150
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Metabolomics Applied to Diabetes Research Moving From Information to Knowledge
Author / Creator:BAIN, James R ; STEVENS, Robert D ; WENNER, Brett R ; ILKAYEVA, Olga ; MUOIO, Deborah M ; NEWGARD, Christopher B
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2009-11, Vol.58 (11), p.2429-2443
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APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease
Author / Creator:Datta, Somenath ; Antonio, Brett M ; Zahler, Nathan H ; Theile, Jonathan W ; Krafte, Doug ; Zhang, Hengtao ; Rosenberg, Paul B ; Chaves, Alec B ; Muoio, Deborah M ; Zhang, Guofang ; Silas, Daniel ; Li, Guojie ; Soldano, Karen ; Nystrom, Sarah ; Ferreira, Davis ; Miller, Sara E ; Bain, James R ; Muehlbauer, Michael J ; Ilkayeva, Olga ; Becker, Thomas C ; Hohmeier, Hans-Ewald ; Newgard, Christopher B ; Olabisi, Opeyemi A
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2024-03, Vol.134 (5)
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Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness
Author / Creator:Huffman, Kim M. ; Koves, Timothy R. ; Hubal, Monica J. ; Abouassi, Hiba ; Beri, Nina ; Bateman, Lori A. ; Stevens, Robert D. ; Ilkayeva, Olga R. ; Hoffman, Eric P. ; Muoio, Deborah M. ; Kraus, William E.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2014-11, Vol.57 (11), p.2282-2295
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Diabetes: The good in fat
Author / Creator:Muoio, Deborah M ; Newgard, Christopher B
Publisher:England
Journal title:Nature (London), 2014-12, Vol.516 (7529), p.49-50
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Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis

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Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption

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Molecular alterations in skeletal muscle in rheumatoid arthritis are related to disease activity, physical inactivity, and disability

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Glucose sensing by MondoA:Mlx complexes: A role for hexokinases and direct regulation of thioredoxin-interacting protein expression

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RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure

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A Lipidomics Analysis of the Relationship Between Dietary Fatty Acid Composition and Insulin Sensitivity in Young Adults

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Rheumatoid arthritis T cell and muscle oxidative metabolism associate with exercise-induced changes in cardiorespiratory fitness

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Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA

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Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection

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ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate

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Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase

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Metabolism and Vascular Fatty Acid Transport

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Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

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Peroxisome Proliferator-Activated Receptor-α Regulates Fatty Acid Utilization in Primary Human Skeletal Muscle Cells

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Physiological and nutritional regulation of enzymes of triacylglycerol synthesis

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HDAC3 sets the timer on muscle fuel switching

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Metabolomics Applied to Diabetes Research Moving From Information to Knowledge

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APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease

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Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness

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Diabetes: The good in fat

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