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Neoadjuvant chemotherapy and nivolumab in resectable non-small-cell lung cancer (NADIM): an open-label, multicentre, single-arm, phase 2 trial
Author / Creator:Provencio, Mariano, MD ; Nadal, Ernest, MD ; Insa, Amelia, MD ; García-Campelo, María Rosario, MD ; Casal-Rubio, Joaquín, MD ; Dómine, Manuel, MD ; Majem, Margarita, MD ; Rodríguez-Abreu, Delvys, MD ; Martínez-Martí, Alex, MD ; De Castro Carpeño, Javier, MD ; Cobo, Manuel, MD ; López Vivanco, Guillermo, MD ; Del Barco, Edel, MD ; Bernabé Caro, Reyes, MD ; Viñolas, Nuria, MD ; Barneto Aranda, Isidoro, MD ; Viteri, Santiago, MD ; Pereira, Eva, MSc ; Royuela, Ana, PhD ; Casarrubios, Marta, MSc ; Salas Antón, Clara, MD ; Parra, Edwin R, PhD ; Wistuba, Ignacio, MD ; Calvo, Virginia, MD ; Laza-Briviesca, Raquel, MSc ; Romero, Atocha, PhD ; Massuti, Bartomeu, MD ; Cruz-Bermúdez, Alberto, PhD
Publisher:London: Elsevier Ltd
Journal title:The lancet oncology, 2020-11, Vol.21 (11), p.1413-1422
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Ramucirumab plus erlotinib in patients with untreated, EGFR-mutated, advanced non-small-cell lung cancer (RELAY): a randomised, double-blind, placebo-controlled, phase 3 trial
Author / Creator:Nakagawa, Kazuhiko, Prof ; Garon, Edward B, MD ; Seto, Takashi, MD ; Nishio, Makoto, MD ; Ponce Aix, Santiago, MD ; Paz-Ares, Luis, Prof ; Chiu, Chao-Hua, MD ; Park, Keunchil, Prof ; Novello, Silvia, Prof ; Nadal, Ernest, MD ; Imamura, Fumio, MD ; Yoh, Kiyotaka, MD ; Shih, Jin-Yuan, MD ; Au, Kwok Hung, MD ; Moro-Sibilot, Denis, Prof ; Enatsu, Sotaro, MD ; Zimmermann, Annamaria, MS ; Frimodt-Moller, Bente, MSc ; Visseren-Grul, Carla, MD ; Reck, Martin, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2019-12, Vol.20 (12), p.1655-1669
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KRAS oncogene in non-small cell lung cancer: clinical perspectives on the treatment of an old target
Author / Creator:Román, Marta ; Baraibar, Iosune ; López, Inés ; Nadal, Ernest ; Rolfo, Christian ; Vicent, Silvestre ; Gil-Bazo, Ignacio
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2018-02, Vol.17 (1), p.33-33, Article 33
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SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo
Author / Creator:Mainardi, Sara ; Mulero-Sánchez, Antonio ; Prahallad, Anirudh ; Germano, Giovanni ; Bosma, Astrid ; Krimpenfort, Paul ; Lieftink, Cor ; Steinberg, Jeffrey D. ; de Wit, Niels ; Gonçalves-Ribeiro, Samuel ; Nadal, Ernest ; Bardelli, Alberto ; Villanueva, Alberto ; Bernards, Rene
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2018-07, Vol.24 (7), p.961-967
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Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells
Author / Creator:Püschel, Franziska ; Favaro, Francesca ; Redondo-Pedraza, Jaime ; Lucendo, Estefanía ; Iurlaro, Raffaella ; Marchetti, Sandrine ; Majem, Blanca ; Eldering, Eric ; Nadal, Ernest ; Ricci, Jean-Ehrland ; Chevet, Eric ; Muñoz-Pinedo, Cristina
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-05, Vol.117 (18), p.9932-9941
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A Novel Serum 4-microRNA Signature for Lung Cancer Detection
Author / Creator:Nadal, Ernest ; Truini, Anna ; Nakata, Asuka ; Lin, Jules ; Reddy, Rishindra M. ; Chang, Andrew C. ; Ramnath, Nithya ; Gotoh, Noriko ; Beer, David G. ; Chen, Guoan
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-07, Vol.5 (1), p.12464-12464, Article 12464
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Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma
Author / Creator:Ambrogio, Chiara ; Gómez-López, Gonzalo ; Falcone, Mattia ; Vidal, August ; Nadal, Ernest ; Crosetto, Nicola ; Blasco, Rafael B ; Fernández-Marcos, Pablo J ; Sánchez-Céspedes, Montserrat ; Ren, Xiaomei ; Wang, Zhen ; Ding, Ke ; Hidalgo, Manuel ; Serrano, Manuel ; Villanueva, Alberto ; Santamaría, David ; Barbacid, Mariano
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-03, Vol.22 (3), p.270-277
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Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours
Author / Creator:Fernandes Neto, João M. ; Nadal, Ernest ; Bosdriesz, Evert ; Ooft, Salo N. ; Farre, Lourdes ; McLean, Chelsea ; Klarenbeek, Sjoerd ; Jurgens, Anouk ; Hagen, Hannes ; Wang, Liqin ; Felip, Enriqueta ; Martinez-Marti, Alex ; Vidal, August ; Voest, Emile ; Wessels, Lodewyk F. A. ; van Tellingen, Olaf ; Villanueva, Alberto ; Bernards, René
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-06, Vol.11 (1), p.1-9, Article 3157
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A phase Ib/II study of galunisertib in combination with nivolumab in solid tumors and non-small cell lung cancer
Author / Creator:Nadal, Ernest ; Saleh, Mansoor ; Aix, Santiago Ponce ; Ochoa-de-Olza, Maria ; Patel, Sandip Pravin ; Antonia, Scott ; Zhao, Yumin ; Gueorguieva, Ivelina ; Man, Michael ; Estrem, Shawn T ; Liu, Jiangang ; Avsar, Emin ; Lin, Wen Hong ; Benhadji, Karim A ; Gandhi, Leena ; Guba, Susan C ; Diaz, Inmaculada Ales
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2023-07, Vol.23 (1), p.708-708, Article 708
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TRAIL receptors promote constitutive and inducible IL-8 secretion in non-small cell lung carcinoma
Author / Creator:Favaro, Francesca ; Luciano-Mateo, Fedra ; Moreno-Caceres, Joaquim ; Hernández-Madrigal, Miguel ; Both, Demi ; Montironi, Chiara ; Püschel, Franziska ; Nadal, Ernest ; Eldering, Eric ; Muñoz-Pinedo, Cristina
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2022-12, Vol.13 (12), p.1046-1046, Article 1046
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Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes
Author / Creator:Dhanasekaran, Saravana M. ; Alejandro Balbin, O ; Chen, Guoan ; Nadal, Ernest ; Kalyana-Sundaram, Shanker ; Pan, Jincheng ; Veeneman, Brendan ; Cao, Xuhong ; Malik, Rohit ; Vats, Pankaj ; Wang, Rui ; Huang, Stephanie ; Zhong, Jinjie ; Jing, Xiaojun ; Iyer, Matthew ; Wu, Yi-Mi ; Harms, Paul W. ; Lin, Jules ; Reddy, Rishindra ; Brennan, Christine ; Palanisamy, Nallasivam ; Chang, Andrew C. ; Truini, Anna ; Truini, Mauro ; Robinson, Dan R. ; Beer, David G. ; Chinnaiyan, Arul M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-12, Vol.5 (1), p.5893-5893, Article 5893
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RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade
Author / Creator:Nokin, Marie-Julie ; Mira, Alessia ; Patrucco, Enrico ; Ricciuti, Biagio ; Cousin, Sophie ; Soubeyran, Isabelle ; San José, Sonia ; Peirone, Serena ; Caizzi, Livia ; Vietti Michelina, Sandra ; Bourdon, Aurelien ; Wang, Xinan ; Alvarez-Villanueva, Daniel ; Martínez-Iniesta, María ; Vidal, August ; Rodrigues, Telmo ; García-Macías, Carmen ; Awad, Mark M. ; Nadal, Ernest ; Villanueva, Alberto ; Italiano, Antoine ; Cereda, Matteo ; Santamaría, David ; Ambrogio, Chiara
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-08, Vol.15 (1), p.7554-18, Article 7554
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Perioperative chemotherapy and nivolumab in non-small-cell lung cancer (NADIM): 5-year clinical outcomes from a multicentre, single-arm, phase 2 trial
Author / Creator:Provencio, Mariano, Prof ; Nadal, Ernest, MD ; Insa, Amelia ; García Campelo, Rosario, MD ; Casal, Joaquín, MD ; Dómine, Manuel, MD ; Massuti, Bartomeu, MD ; Majem, Margarita, MD ; Rodríguez-Abreu, Delvys, MD ; Martínez-Martí, Alex, MD ; de Castro, Javier, MD ; Gómez de Antonio, David, MD ; Macia, Iván, MD ; Figueroa, Santiago, MD ; Fernández Vago, Luís, MD ; Calvo, Virginia, MD ; Palmero, Ramón, MD ; Sierra-Rodero, Belén, MSc ; Martínez-Toledo, Cristina, MSc ; Molina-Alejandre, Marta, MSc ; Serna-Blasco, Roberto, PhD ; Romero, Atocha, PhD ; Cruz-Bermúdez, Alberto, PhD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-11, Vol.25 (11), p.1453-1464
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Tepotinib plus osimertinib in patients with EGFR-mutated non-small-cell lung cancer with MET amplification following progression on first-line osimertinib (INSIGHT 2): a multicentre, open-label, phase...
Author / Creator:Wu, Yi-Long, Prof ; Guarneri, Valentina, Prof ; Voon, Pei Jye, MD ; Lim, Boon Khaw, MRCP ; Yang, Jin-Ji, Prof ; Wislez, Marie, Prof ; Huang, Cheng, Prof ; Liam, Chong Kin, Prof ; Mazieres, Julien, Prof ; Tho, Lye Mun, PhD ; Hayashi, Hidetoshi, Prof ; Nhung, Nguyen Viet, PhD ; Chia, Puey Ling, PhD ; de Marinis, Filippo, Prof ; Raskin, Jo, MD ; Zhou, Qinghua, Prof ; Finocchiaro, Giovanna, MD ; Le, Anh Tuan, PhD ; Wang, Jialei, Prof ; Dooms, Christophe, PhD ; Kato, Terufumi, PhD ; Nadal, Ernest, PhD ; Hin, How Soon, Prof ; Smit, Egbert F, Prof ; Wermke, Martin, Prof ; Tan, Daniel, PhD ; Morise, Masahiro, PhD ; O'Brate, Aurora, PhD ; Adrian, Svenja, MD ; Pfeiffer, Boris M, MD ; Stroh, Christopher, PhD ; Juraeva, Dilafruz, PhD ; Strotmann, Rainer, MD ; Goteti, Kosalaram, MD ; Berghoff, Karin, MD ; Ellers-Lenz, Barbara, MSc ; Karachaliou, Niki, MD ; Le, Xiuning, MD ; Kim, Tae Min, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-08, Vol.25 (8), p.989-1002
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Clinical and economic impact of 'ROS1-testing' strategy compared to a 'no-ROS1-testing' strategy in advanced NSCLC in Spain
Author / Creator:Rojo, Federico ; Conde, Esther ; Torres, Héctor ; Cabezón-Gutiérrez, Luis ; Bautista, Dolores ; Ramos, Inmaculada ; Carcedo, David ; Arrabal, Natalia ; García, J Francisco ; Galán, Raquel ; Nadal, Ernest
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2022-03, Vol.22 (1), p.292-292, Article 292
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ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endometrial canc...
Author / Creator:Leary, Alexandra ; Estévez-García, Purificación ; Sabatier, Renaud ; Ray-Coquard, Isabelle ; Romeo, Margarita ; Barretina-Ginesta, Pilar ; Gil-Martin, Marta ; Garralda, Elena ; Bosch-Barrera, Joaquim ; Morán, Teresa ; Martin-Martorell, Paloma ; Nadal, Ernest ; Gascón, Pere ; Rodon, Jordi ; Lizcano, Jose M ; Muñoz-Guardiola, Pau ; Fierro-Durán, Gemma ; Pedrós-Gámez, Oriol ; Pérez-Montoyo, Héctor ; Yeste-Velasco, Marc ; Cortal, Marc ; Pérez-Campos, Antonio ; Alfon, Jose ; Domenech, Carles ; Pérez-Fidalgo, Alejandro ; Oaknin, Ana
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2024-07, Vol.24 (1), p.876-14, Article 876
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Fasting plasma glucose is an independent predictor of survival in patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy
Author / Creator:Bergamino, Milana ; Rullan, Antonio J ; Saigí, Maria ; Peiró, Inmaculada ; Montanya, Eduard ; Palmero, Ramón ; Ruffinelli, José Carlos ; Navarro, Arturo ; Arnaiz, María Dolores ; Brao, Isabel ; Aso, Samantha ; Padrones, Susana ; Cardenal, Felipe ; Nadal, Ernest
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2019-02, Vol.19 (1), p.165-165, Article 165
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Clinical and economic impact of current ALK rearrangement testing in Spain compared with a hypothetical no-testing scenario
Author / Creator:Nadal, Ernest ; Bautista, Dolores ; Cabezón-Gutiérrez, Luis ; Ortega, Ana Laura ; Torres, Héctor ; Carcedo, David ; Ruiz de Alda, Lucía ; Garcia, J Francisco ; Vieitez, Paula ; Rojo, Federico
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2021-06, Vol.21 (1), p.689-13, Article 689
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Correction: ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endo...
Author / Creator:Leary, Alexandra ; Estévez-García, Purificación ; Sabatier, Renaud ; Ray-Coquard, Isabelle ; Romeo, Margarita ; Barretina-Ginesta, Pilar ; Gil-Martin, Marta ; Garralda, Elena ; Bosch-Barrera, Joaquim ; Morán, Teresa ; Martin-Martorell, Paloma ; Nadal, Ernest ; Gascón, Pere ; Rodon, Jordi ; Lizcano, Jose M ; Muéoz-Guardiola, Pau ; Fierro-Durán, Gemma ; Pedrós-Gámez, Oriol ; Pérez-Montoyo, Héctor ; Yeste-Velasco, Marc ; Cortal, Marc ; Pérez-Campos, Antonio ; Alfon, Jose ; Domenech, Carles ; Pérez-Fidalgo, Alejandro ; Oaknin, Ana
Publisher:London: BioMed Central Ltd
Journal title:BMC cancer, 2024-07, Vol.24 (1), p.1-2
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Transcriptional analysis of landmark molecular pathways in lung adenocarcinoma results in a clinically relevant classification with potential therapeutic implications
Author / Creator:Hijazo‐Pechero, Sara ; Alay, Ania ; Cordero, David ; Marín, Raúl ; Vilariño, Noelia ; Palmero, Ramón ; Brenes, Jesús ; Montalban‐Casafont, Aina ; Nadal, Ernest ; Solé, Xavier
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2024-02, Vol.18 (2), p.453-470
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Neoadjuvant chemotherapy and nivolumab in resectable non-small-cell lung cancer (NADIM): an open-label, multicentre, single-arm, phase 2 trial

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Ramucirumab plus erlotinib in patients with untreated, EGFR-mutated, advanced non-small-cell lung cancer (RELAY): a randomised, double-blind, placebo-controlled, phase 3 trial

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KRAS oncogene in non-small cell lung cancer: clinical perspectives on the treatment of an old target

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SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo

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Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells

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A Novel Serum 4-microRNA Signature for Lung Cancer Detection

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Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma

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Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours

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A phase Ib/II study of galunisertib in combination with nivolumab in solid tumors and non-small cell lung cancer

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TRAIL receptors promote constitutive and inducible IL-8 secretion in non-small cell lung carcinoma

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Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes

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RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade

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Perioperative chemotherapy and nivolumab in non-small-cell lung cancer (NADIM): 5-year clinical outcomes from a multicentre, single-arm, phase 2 trial

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Tepotinib plus osimertinib in patients with EGFR-mutated non-small-cell lung cancer with MET amplification following progression on first-line osimertinib (INSIGHT 2): a multicentre, open-label, phase...

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Clinical and economic impact of 'ROS1-testing' strategy compared to a 'no-ROS1-testing' strategy in advanced NSCLC in Spain

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ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endometrial canc...

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Fasting plasma glucose is an independent predictor of survival in patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy

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Clinical and economic impact of current ALK rearrangement testing in Spain compared with a hypothetical no-testing scenario

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Correction: ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endo...

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Transcriptional analysis of landmark molecular pathways in lung adenocarcinoma results in a clinically relevant classification with potential therapeutic implications

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