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Newsletter articlesFull Text
Matsuo Hirotaka, Nakayama Akiyoshi and Tokyo University of Pharmacy and Life Sciences Submit Patent Application for Method of Evaluating Urinary Excreted Substance Amount/urine Volume
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2025
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Tokyo Univ of Pharmacy Life Sciences, Nakayama Akiyoshi and Matsuo Hirotaka Submit Patent Application for Excreted Urinary Matter Amount and Urine Amount Evaluation Method
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2024
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Newsletter articlesFull Text
INTERNATIONAL PATENT: MATSUO HIROTAKA, 松尾　洋孝, NAKAYAMA AKIYOSHI, 中山　昌喜, TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES, 学校法人東京薬科大学 FILES APPLICATION FOR "EXCRETED URINARY MATTER AMOUNT AND URINE AMOUN...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2023
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ArticlesPeer ReviewedFull Text
Recent Advances in Dysuricemia: Toward Optimal Serum Urate Level
Author / Creator:Kurajoh, Masafumi ; Nakayama, Akiyoshi
Publisher:Switzerland: MDPI AG
Journal title:Biomedicines, 2024-05, Vol.12 (5), p.1094
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Decreased extra-renal urate excretion is a common cause of hyperuricemia
Author / Creator:Ichida, Kimiyoshi ; Matsuo, Hirotaka ; Takada, Tappei ; Nakayama, Akiyoshi ; Murakami, Keizo ; Shimizu, Toru ; Yamanashi, Yoshihide ; Kasuga, Hiroshi ; Nakashima, Hiroshi ; Nakamura, Takahiro ; Takada, Yuzo ; Kawamura, Yusuke ; Inoue, Hiroki ; Okada, Chisa ; Utsumi, Yoshitaka ; Ikebuchi, Yuki ; Ito, Kousei ; Nakamura, Makiko ; Shinohara, Yoshihiko ; Hosoyamada, Makoto ; Sakurai, Yutaka ; Shinomiya, Nariyoshi ; Hosoya, Tatsuo ; Suzuki, Hiroshi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2012-04, Vol.3 (1), p.764-764, Article 764
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Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels
Author / Creator:Higashino, Toshihide ; Morimoto, Keito ; Nakaoka, Hirofumi ; Toyoda, Yu ; Kawamura, Yusuke ; Shimizu, Seiko ; Nakamura, Takahiro ; Hosomichi, Kazuyoshi ; Nakayama, Akiyoshi ; Ooyama, Keiko ; Ooyama, Hiroshi ; Shimizu, Toru ; Ueno, Miki ; Ito, Toshimitsu ; Tamura, Takashi ; Naito, Mariko ; Nakashima, Hiroshi ; Kawaguchi, Makoto ; Takao, Mikiya ; Kawai, Yosuke ; Osada, Naoki ; Ichida, Kimiyoshi ; Yamamoto, Ken ; Suzuki, Hiroshi ; Shinomiya, Nariyoshi ; Inoue, Ituro ; Takada, Tappei ; Matsuo, Hirotaka
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2020-01, Vol.79 (1), p.164-166
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ArticlesPeer ReviewedFull Text
Dysuricemia
Author / Creator:Nakayama, Akiyoshi ; Kurajoh, Masafumi ; Toyoda, Yu ; Takada, Tappei ; Ichida, Kimiyoshi ; Matsuo, Hirotaka
Publisher:Switzerland: MDPI AG
Journal title:Biomedicines, 2023-11, Vol.11 (12), p.3169
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ArticlesPeer ReviewedFull Text
ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload
Author / Creator:Matsuo, Hirotaka ; Nakayama, Akiyoshi ; Sakiyama, Masayuki ; Chiba, Toshinori ; Shimizu, Seiko ; Kawamura, Yusuke ; Nakashima, Hiroshi ; Nakamura, Takahiro ; Takada, Yuzo ; Oikawa, Yuji ; Takada, Tappei ; Nakaoka, Hirofumi ; Abe, Junko ; Inoue, Hiroki ; Wakai, Kenji ; Kawai, Sayo ; Guang, Yin ; Nakagawa, Hiroko ; Ito, Toshimitsu ; Niwa, Kazuki ; Yamamoto, Ken ; Sakurai, Yutaka ; Suzuki, Hiroshi ; Hosoya, Tatsuo ; Ichida, Kimiyoshi ; Shimizu, Toru ; Shinomiya, Nariyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2014-01, Vol.4 (1), p.3755-3755, Article 3755
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Newsletter articlesFull Text
WIPO PUBLISHES PATENT OF RICOH, KOUSUKE NAGATA, MASAHIDE YAMADA, SHINYA NAKAYAMA, AKIYOSHI SABU, TATSUYA MORITA, TAKAMASA HASE, SUZUKA AMEMORI AND RINTARO TAKAHASHI FOR "TONER, DEVELOPER AND IMAGE FOR...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2014
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ArticlesPeer ReviewedFull Text
Common dysfunctional variants in ABCG2 are a major cause of early-onset gout
Author / Creator:Matsuo, Hirotaka ; Ichida, Kimiyoshi ; Takada, Tappei ; Nakayama, Akiyoshi ; Nakashima, Hiroshi ; Nakamura, Takahiro ; Kawamura, Yusuke ; Takada, Yuzo ; Yamamoto, Ken ; Inoue, Hiroki ; Oikawa, Yuji ; Naito, Mariko ; Hishida, Asahi ; Wakai, Kenji ; Okada, Chisa ; Shimizu, Seiko ; Sakiyama, Masayuki ; Chiba, Toshinori ; Ogata, Hiraku ; Niwa, Kazuki ; Hosoyamada, Makoto ; Mori, Atsuyoshi ; Hamajima, Nobuyuki ; Suzuki, Hiroshi ; Kanai, Yoshikatsu ; Sakurai, Yutaka ; Hosoya, Tatsuo ; Shimizu, Toru ; Shinomiya, Nariyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2013-06, Vol.3 (1), p.2014-2014, Article 2014
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ArticlesPeer ReviewedFull Text
Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2
Author / Creator:Matsuo, Hirotaka ; Tsunoda, Tomoyuki ; Ooyama, Keiko ; Sakiyama, Masayuki ; Sogo, Tsuyoshi ; Takada, Tappei ; Nakashima, Akio ; Nakayama, Akiyoshi ; Kawaguchi, Makoto ; Higashino, Toshihide ; Wakai, Kenji ; Ooyama, Hiroshi ; Hokari, Ryota ; Suzuki, Hiroshi ; Ichida, Kimiyoshi ; Inui, Ayano ; Fujimori, Shin ; Shinomiya, Nariyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-08, Vol.6 (1), p.31003-31003, Article 31003
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ArticlesPeer ReviewedFull Text
Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors
Author / Creator:Nakayama, Akiyoshi ; Matsuo, Hirotaka ; Nakaoka, Hirofumi ; Nakamura, Takahiro ; Nakashima, Hiroshi ; Takada, Yuzo ; Oikawa, Yuji ; Takada, Tappei ; Sakiyama, Masayuki ; Shimizu, Seiko ; Kawamura, Yusuke ; Chiba, Toshinori ; Abe, Junko ; Wakai, Kenji ; Kawai, Sayo ; Okada, Rieko ; Tamura, Takashi ; Shichijo, Yuka ; Akashi, Airi ; Suzuki, Hiroshi ; Hosoya, Tatsuo ; Sakurai, Yutaka ; Ichida, Kimiyoshi ; Shinomiya, Nariyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2014-06, Vol.4 (1), p.5227, Article 5227
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ArticlesPeer ReviewedFull Text
Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus
Author / Creator:Sakiyama, Masayuki ; Matsuo, Hirotaka ; Nakaoka, Hirofumi ; Yamamoto, Ken ; Nakayama, Akiyoshi ; Nakamura, Takahiro ; Kawai, Sayo ; Okada, Rieko ; Ooyama, Hiroshi ; Shimizu, Toru ; Shinomiya, Nariyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-05, Vol.6 (1), p.25360-25360, Article 25360
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ArticlesPeer ReviewedFull Text
The effects of URAT1/SLC22A12 nonfunctional variants,R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression
Author / Creator:Sakiyama, Masayuki ; Matsuo, Hirotaka ; Shimizu, Seiko ; Nakashima, Hiroshi ; Nakamura, Takahiro ; Nakayama, Akiyoshi ; Higashino, Toshihide ; Naito, Mariko ; Suma, Shino ; Hishida, Asahi ; Satoh, Takahiro ; Sakurai, Yutaka ; Takada, Tappei ; Ichida, Kimiyoshi ; Ooyama, Hiroshi ; Shimizu, Toru ; Shinomiya, Nariyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-01, Vol.6 (1), p.20148-20148, Article 20148
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ArticlesPeer ReviewedFull Text
Coffee Consumption Reduces Gout Risk Independently of Serum Uric Acid Levels: Mendelian Randomization Analyses Across Ancestry Populations
Author / Creator:Shirai, Yuya ; Nakayama, Akiyoshi ; Kawamura, Yusuke ; Toyoda, Yu ; Nakatochi, Masahiro ; Shimizu, Seiko ; Shinomiya, Nariyoshi ; Okada, Yukinori ; Matsuo, Hirotaka
Publisher:Boston, USA: Wiley Periodicals, Inc
Journal title:ACR open rheumatology, 2022-06, Vol.4 (6), p.534-539
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ArticlesPeer ReviewedFull Text
Independent effects of ADH1B and ALDH2 common dysfunctional variants on gout risk
Author / Creator:Sakiyama, Masayuki ; Matsuo, Hirotaka ; Akashi, Airi ; Shimizu, Seiko ; Higashino, Toshihide ; Kawaguchi, Makoto ; Nakayama, Akiyoshi ; Naito, Mariko ; Kawai, Sayo ; Nakashima, Hiroshi ; Sakurai, Yutaka ; Ichida, Kimiyoshi ; Shimizu, Toru ; Ooyama, Hiroshi ; Shinomiya, Nariyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-05, Vol.7 (1), p.2500-6, Article 2500
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ArticlesPeer ReviewedFull Text
Carrier frequency of the GJB2 mutations that cause hereditary hearing loss in the Japanese population
Author / Creator:Taniguchi, Mirei ; Matsuo, Hirotaka ; Shimizu, Seiko ; Nakayama, Akiyoshi ; Suzuki, Koji ; Hamajima, Nobuyuki ; Shinomiya, Nariyoshi ; Nishio, Shinya ; Kosugi, Shinji ; Usami, Shin-ichi ; Ito, Juichi ; Kitajiri, Shin-ichiro
Publisher:England: Nature Publishing Group
Journal title:Journal of human genetics, 2015-10, Vol.60 (10), p.613-617
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ArticlesPeer ReviewedFull Text
Common variant of BCAS3 is associated with gout risk in Japanese population: the first replication study after gout GWAS in Han Chinese
Author / Creator:Sakiyama, Masayuki ; Matsuo, Hirotaka ; Nakaoka, Hirofumi ; Kawamura, Yusuke ; Kawaguchi, Makoto ; Higashino, Toshihide ; Nakayama, Akiyoshi ; Akashi, Airi ; Ueyama, Jun ; Kondo, Takaaki ; Wakai, Kenji ; Sakurai, Yutaka ; Yamamoto, Ken ; Ooyama, Hiroshi ; Shinomiya, Nariyoshi
Publisher:England: BioMed Central Ltd
Journal title:BMC medical genetics, 2018-06, Vol.19 (1), p.96-96, Article 96
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A Proposal for Practical Diagnosis of Renal Hypouricemia: Evidenced from Genetic Studies of Nonfunctional Variants of URAT1/SLC22A12 among 30,685 Japanese Individuals
Author / Creator:Kawamura, Yusuke ; Nakayama, Akiyoshi ; Shimizu, Seiko ; Toyoda, Yu ; Nishida, Yuichiro ; Hishida, Asahi ; Katsuura-Kamano, Sakurako ; Shibuya, Kenichi ; Tamura, Takashi ; Kawaguchi, Makoto ; Suzuki, Satoko ; Iwasawa, Satoko ; Nakashima, Hiroshi ; Ibusuki, Rie ; Uemura, Hirokazu ; Hara, Megumi ; Takeuchi, Kenji ; Takada, Tappei ; Tsunoda, Masashi ; Arisawa, Kokichi ; Takezaki, Toshiro ; Tanaka, Keitaro ; Ichida, Kimiyoshi ; Wakai, Kenji ; Shinomiya, Nariyoshi ; Matsuo, Hirotaka
Publisher:Switzerland: MDPI AG
Journal title:Biomedicines, 2021-08, Vol.9 (8), p.1012
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ArticlesPeer ReviewedFull Text
Measurement of trapped flux magnetic field near the superconducting film by the dependence of superconducting current through a Josephson junction sensor
Author / Creator:Nakayama, Akiyoshi ; Nishi, Yohei ; Watanabe, Norimichi ; Abe, Susumu ; Okabe, Yoichi
Publisher:Bristol: IOP Publishing
Journal title:Journal of physics. Conference series, 2010-06, Vol.234 (4)
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Matsuo Hirotaka, Nakayama Akiyoshi and Tokyo University of Pharmacy and Life Sciences Submit Patent Application for Method of Evaluating Urinary Excreted Substance Amount/urine Volume

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Tokyo Univ of Pharmacy Life Sciences, Nakayama Akiyoshi and Matsuo Hirotaka Submit Patent Application for Excreted Urinary Matter Amount and Urine Amount Evaluation Method

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INTERNATIONAL PATENT: MATSUO HIROTAKA, 松尾 洋孝, NAKAYAMA AKIYOSHI, 中山 昌喜, TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES, 学校法人東京薬科大学 FILES APPLICATION FOR "EXCRETED URINARY MATTER AMOUNT AND URINE AMOUN...

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Recent Advances in Dysuricemia: Toward Optimal Serum Urate Level

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Decreased extra-renal urate excretion is a common cause of hyperuricemia

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Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

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Dysuricemia

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ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload

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WIPO PUBLISHES PATENT OF RICOH, KOUSUKE NAGATA, MASAHIDE YAMADA, SHINYA NAKAYAMA, AKIYOSHI SABU, TATSUYA MORITA, TAKAMASA HASE, SUZUKA AMEMORI AND RINTARO TAKAHASHI FOR "TONER, DEVELOPER AND IMAGE FOR...

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Common dysfunctional variants in ABCG2 are a major cause of early-onset gout

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Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2

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Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors

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Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus

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The effects of URAT1/SLC22A12 nonfunctional variants,R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression

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Coffee Consumption Reduces Gout Risk Independently of Serum Uric Acid Levels: Mendelian Randomization Analyses Across Ancestry Populations

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Independent effects of ADH1B and ALDH2 common dysfunctional variants on gout risk

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Carrier frequency of the GJB2 mutations that cause hereditary hearing loss in the Japanese population

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Common variant of BCAS3 is associated with gout risk in Japanese population: the first replication study after gout GWAS in Han Chinese

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A Proposal for Practical Diagnosis of Renal Hypouricemia: Evidenced from Genetic Studies of Nonfunctional Variants of URAT1/SLC22A12 among 30,685 Japanese Individuals

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Measurement of trapped flux magnetic field near the superconducting film by the dependence of superconducting current through a Josephson junction sensor

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INTERNATIONAL PATENT: MATSUO HIROTAKA, 松尾　洋孝, NAKAYAMA AKIYOSHI, 中山　昌喜, TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES, 学校法人東京薬科大学 FILES APPLICATION FOR "EXCRETED URINARY MATTER AMOUNT AND URINE AMOUN...