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Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies
Author / Creator:Pombo Antunes, Ana Rita ; Scheyltjens, Isabelle ; Duerinck, Johnny ; Neyns, Bart ; Movahedi, Kiavash ; Van Ginderachter, Jo A
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-02, Vol.9
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Pembrolizumab versus Ipilimumab in Advanced Melanoma
Author / Creator:Robert, Caroline ; Schachter, Jacob ; Long, Georgina V ; Arance, Ana ; Grob, Jean Jacques ; Mortier, Laurent ; Daud, Adil ; Carlino, Matteo S ; McNeil, Catriona ; Lotem, Michal ; Larkin, James ; Lorigan, Paul ; Neyns, Bart ; Blank, Christian U ; Hamid, Omid ; Mateus, Christine ; Shapira-Frommer, Ronnie ; Kosh, Michele ; Zhou, Honghong ; Ibrahim, Nageatte ; Ebbinghaus, Scot ; Ribas, Antoni
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2015-06, Vol.372 (26), p.2521-2532
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Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study
Author / Creator:Robert, Caroline, Prof ; Ribas, Antoni, Prof ; Schachter, Jacob, Prof ; Arance, Ana, MD ; Grob, Jean-Jacques, Prof ; Mortier, Laurent, Prof ; Daud, Adil, Prof ; Carlino, Matteo S, MB ; McNeil, Catriona M, MD ; Lotem, Michal, Prof ; Larkin, James M G, Prof ; Lorigan, Paul, Prof ; Neyns, Bart, Prof ; Blank, Christian U, Prof ; Petrella, Teresa M, MD ; Hamid, Omid, MD ; Su, Shu-Chih, PhD ; Krepler, Clemens, MD ; Ibrahim, Nageatte, MD ; Long, Georgina V, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2019-09, Vol.20 (9), p.1239-1251
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TriMix and tumor antigen mRNA electroporated dendritic cell vaccination plus ipilimumab: link between T-cell activation and clinical responses in advanced melanoma
Author / Creator:De Keersmaecker, Brenda ; Claerhout, Sofie ; Carrasco, Javier ; Bar, Isabelle ; Corthals, Jurgen ; Wilgenhof, Sofie ; Neyns, Bart ; Thielemans, Kris
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2020-02, Vol.8 (1), p.e000329
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A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disea...
Author / Creator:Jansen, Yanina ; Kruse, Vibeke ; Corthals, Jurgen ; Schats, Kelly ; van Dam, Pieter-Jan ; Seremet, Teofila ; Heirman, Carlo ; Brochez, Lieve ; Kockx, Mark ; Thielemans, Kris ; Neyns, Bart
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2020-12, Vol.69 (12), p.2589-2598
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Undetectable circulating tumor DNA (ctDNA) levels correlate with favorable outcome in metastatic melanoma patients treated with anti-PD1 therapy
Author / Creator:Seremet, Teofila ; Jansen, Yanina ; Planken, Simon ; Njimi, Hassan ; Delaunoy, Mélanie ; El Housni, Hakim ; Awada, Gil ; Schwarze, Julia Katharina ; Keyaerts, Marleen ; Everaert, Hendrik ; Lienard, Danielle ; Del Marmol, Véronique ; Heimann, Pierre ; Neyns, Bart
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2019-09, Vol.17 (1), p.303-303, Article 303
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Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study
Author / Creator:Wolchok, Jedd D, Dr ; Neyns, Bart, MD ; Linette, Gerald, MD ; Negrier, Sylvie, Prof ; Lutzky, Jose, MD ; Thomas, Luc, Prof ; Waterfield, William, MD ; Schadendorf, Dirk, Prof ; Smylie, Michael, Prof ; Guthrie, Troy, MD ; Grob, Jean-Jacques, Prof ; Chesney, Jason, MD ; Chin, Kevin, MD ; Chen, Kun, PhD ; Hoos, Axel, MD ; O'Day, Steven J, MD ; Lebbé, Celeste, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2010-02, Vol.11 (2), p.155-164
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Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
Author / Creator:Van Damme, Helena ; Dombrecht, Bruno ; Kiss, Máté ; Roose, Heleen ; Allen, Elizabeth ; Van Overmeire, Eva ; Kancheva, Daliya ; Martens, Liesbet ; Murgaski, Aleksandar ; Bardet, Pauline Madeleine Rachel ; Blancke, Gillian ; Jans, Maude ; Bolli, Evangelia ; Martins, Maria Solange ; Elkrim, Yvon ; Dooley, James ; Boon, Louis ; Schwarze, Julia Katharina ; Tacke, Frank ; Movahedi, Kiavash ; Vandamme, Niels ; Neyns, Bart ; Ocak, Sebahat ; Scheyltjens, Isabelle ; Vereecke, Lars ; Nana, Frank Aboubakar ; Merchiers, Pascal ; Laoui, Damya ; Van Ginderachter, Jo Agnes
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-02, Vol.9 (2), p.e001749
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ArticlesPeer ReviewedFull Text
The clinical application of cancer immunotherapy based on naturally circulating dendritic cells
Author / Creator:Bol, Kalijn F ; Schreibelt, Gerty ; Rabold, Katrin ; Wculek, Stefanie K ; Schwarze, Julia Katharina ; Dzionek, Andrzej ; Teijeira, Alvaro ; Kandalaft, Lana E ; Romero, Pedro ; Coukos, George ; Neyns, Bart ; Sancho, David ; Melero, Ignacio ; de Vries, I Jolanda M
Publisher:England: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2019-04, Vol.7 (1), p.109-109, Article 109
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ArticlesPeer ReviewedFull Text
18F-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma
Author / Creator:Wong, Annie ; Callahan, Jason ; Keyaerts, Marleen ; Neyns, Bart ; Mangana, Johanna ; Aberle, Susanne ; Herschtal, Alan ; Fullerton, Sonia ; Milne, Donna ; Iravani, Amir ; McArthur, Grant A ; Hicks, Rodney J
Publisher:London: BioMed Central Ltd
Journal title:Cancer imaging, 2020-05, Vol.20 (1), p.1-36, Article 36
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ArticlesPeer ReviewedFull Text
Intracerebral administration of CTLA-4 and PD-1 immune checkpoint blocking monoclonal antibodies in patients with recurrent glioblastoma: a phase I clinical trial
Author / Creator:Duerinck, Johnny ; Schwarze, Julia Katharina ; Awada, Gil ; Tijtgat, Jens ; Vaeyens, Freya ; Bertels, Cleo ; Geens, Wietse ; Klein, Samuel ; Seynaeve, Laura ; Cras, Louise ; D’Haene, Nicky ; Michotte, Alex ; Caljon, Ben ; Salmon, Isabelle ; Bruneau, Michaël ; Kockx, Mark ; Van Dooren, Sonia ; Vanbinst, Anne-Marie ; Everaert, Hendrik ; Forsyth, Ramses ; Neyns, Bart
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-06, Vol.9 (6), p.e002296
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ArticlesPeer ReviewedFull Text
Pembrolizumab versus Ipilimumab in Advanced Melanoma
Author / Creator:Robert, Caroline ; Schachter, Jacob ; Long, Georgina V. ; Arance, Ana ; Grob, Jean Jacques ; Mortier, Laurent ; Daud, Adil ; Carlino, Matteo S. ; McNeil, Catriona ; Lotem, Michal ; Larkin, James ; Lorigan, Paul ; Neyns, Bart ; Blank, Christian U. ; Hamid, Omid ; Mateus, Christine ; Shapira-Frommer, Ronnie ; Kosh, Michele ; Zhou, Honghong ; Ibrahim, Nageatte ; Ebbinghaus, Scot ; Ribas, Antoni
Journal title:The New England journal of medicine, 2015-06, Vol.372 (26), p.2521-2532
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ArticlesPeer ReviewedFull Text
Pembrolizumab for the treatment of uveal melanoma: A case series
Author / Creator:Jansen, Yanina Jeanne Leona ; Seremet, Teofila ; Neyns, Bart
Publisher:London, England: SAGE Publications
Journal title:Rare tumors, 2020, Vol.12, p.2036361320971983-2036361320971983
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Optimal Evaluation of Programmed Death Ligand-1 on Tumor Cells Versus Immune Cells Requires Different Detection Methods
Author / Creator:Schats, Kelly A ; Van Vré, Emily A ; Boeckx, Carolien ; De Bie, Martine ; Schrijvers, Dorien M ; Neyns, Bart ; De Meester, Ingrid ; Kockx, Mark M
Publisher:United States: College of American Pathologists
Journal title:Archives of pathology & laboratory medicine (1976), 2018-08, Vol.142 (8), p.982-991
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Axitinib plus avelumab in the treatment of recurrent glioblastoma: a stratified, open-label, single-center phase 2 clinical trial (GliAvAx)
Author / Creator:Awada, Gil ; Ben Salama, Laila ; De Cremer, Jennifer ; Schwarze, Julia Katharina ; Fischbuch, Lydia ; Seynaeve, Laura ; Du Four, Stephanie ; Vanbinst, Anne-Marie ; Michotte, Alex ; Everaert, Hendrik ; Rogiers, Anne ; Theuns, Peter ; Duerinck, Johnny ; Neyns, Bart
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2020-10, Vol.8 (2), p.e001146
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Acute exudative polymorphous vitelliform maculopathy during pembrolizumab treatment for metastatic melanoma: a case report
Author / Creator:Lambert, Ine ; Fasolino, Giuseppe ; Awada, Gil ; Kuijpers, Robert ; ten Tusscher, Marcel ; Neyns, Bart
Publisher:London: BioMed Central Ltd
Journal title:BMC ophthalmology, 2021-06, Vol.21 (1), p.1-8, Article 250
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Neurocognitive Function, Psychosocial Outcome, and Health-Related Quality of Life of the First-Generation Metastatic Melanoma Survivors Treated with Ipilimumab
Author / Creator:De Ridder, Mark ; Bernheim, Jan L. ; Neyns, Bart ; Theuns, Peter ; De Cremer, Jennifer ; Schwarze, Julia K. ; Awada, Gil ; Schembri, Adrian ; Lauwyck, Justine ; Leys, Christophe ; Rogiers, Anne ; Maruff, Paul
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Journal of immunology research, 2020, Vol.2020 (2020), p.1-11
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Intratumoral administration of CD1c (BDCA-1)+ and CD141 (BDCA-3)+ myeloid dendritic cells in combination with talimogene laherparepvec in immune checkpoint blockade refractory advanced melanoma patien...
Author / Creator:Schwarze, Julia Katharina ; Tijtgat, Jens ; Awada, Gil ; Cras, Louise ; Vasaturo, Angela ; Bagnall, Christopher ; Forsyth, Ramses ; Dufait, Inès ; Tuyaerts, Sandra ; Van Riet, Ivan ; Neyns, Bart
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2022-09, Vol.10 (9), p.e005141
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Preclinical evaluation of antigen-sensitive B7-H3-targeting nanobody-based CAR-T cells in glioblastoma cautions for on-target, off-tumor toxicity
Author / Creator:Meeus, Fien ; Funeh, Cyprine Neba ; Awad, Robin Maximilian ; Zeven, Katty ; Autaers, Dorien ; De Becker, Ann ; Van Riet, Ivan ; Goyvaerts, Cleo ; Tuyaerts, Sandra ; Neyns, Bart ; Devoogdt, Nick ; De Vlaeminck, Yannick ; Breckpot, Karine
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2024-11, Vol.12 (11), p.e009110
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Intratumoral administration of the immunologic adjuvant AS01B in combination with autologous CD1c (BDCA-1)+/CD141 (BDCA-3)+ myeloid dendritic cells plus ipilimumab and intravenous nivolumab in patient...
Author / Creator:Tijtgat, Jens ; Geeraerts, Xenia ; Boisson, Anais ; Stevens, Latoya ; Vounckx, Manon ; Dirven, Iris ; Schwarze, Julia Katharina ; Raeymaeckers, Steven ; Forsyth, Ramses ; Van Riet, Ivan ; Tuyaerts, Sandra ; Willard-Gallo, Karen ; Neyns, Bart
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2024-01, Vol.12 (1), p.e008148
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Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies

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Pembrolizumab versus Ipilimumab in Advanced Melanoma

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Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study

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TriMix and tumor antigen mRNA electroporated dendritic cell vaccination plus ipilimumab: link between T-cell activation and clinical responses in advanced melanoma

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A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disea...

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Undetectable circulating tumor DNA (ctDNA) levels correlate with favorable outcome in metastatic melanoma patients treated with anti-PD1 therapy

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Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study

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Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy

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The clinical application of cancer immunotherapy based on naturally circulating dendritic cells

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18F-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

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Intracerebral administration of CTLA-4 and PD-1 immune checkpoint blocking monoclonal antibodies in patients with recurrent glioblastoma: a phase I clinical trial

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Pembrolizumab versus Ipilimumab in Advanced Melanoma

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Pembrolizumab for the treatment of uveal melanoma: A case series

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Optimal Evaluation of Programmed Death Ligand-1 on Tumor Cells Versus Immune Cells Requires Different Detection Methods

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Axitinib plus avelumab in the treatment of recurrent glioblastoma: a stratified, open-label, single-center phase 2 clinical trial (GliAvAx)

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Acute exudative polymorphous vitelliform maculopathy during pembrolizumab treatment for metastatic melanoma: a case report

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Neurocognitive Function, Psychosocial Outcome, and Health-Related Quality of Life of the First-Generation Metastatic Melanoma Survivors Treated with Ipilimumab

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Intratumoral administration of CD1c (BDCA-1)+ and CD141 (BDCA-3)+ myeloid dendritic cells in combination with talimogene laherparepvec in immune checkpoint blockade refractory advanced melanoma patien...

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Preclinical evaluation of antigen-sensitive B7-H3-targeting nanobody-based CAR-T cells in glioblastoma cautions for on-target, off-tumor toxicity

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Intratumoral administration of the immunologic adjuvant AS01B in combination with autologous CD1c (BDCA-1)+/CD141 (BDCA-3)+ myeloid dendritic cells plus ipilimumab and intravenous nivolumab in patient...

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