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ArticlesPeer ReviewedFull Text
Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer
Author / Creator:Eskander, Ramez N. ; Sill, Michael W. ; Beffa, Lindsey ; Moore, Richard G. ; Hope, Joanie M. ; Musa, Fernanda B. ; Mannel, Robert ; Shahin, Mark S. ; Cantuaria, Guilherme H. ; Girda, Eugenia ; Mathews, Cara ; Kavecansky, Juraj ; Leath, Charles A. ; Gien, Lilian T. ; Hinchcliff, Emily M. ; Lele, Shashikant B. ; Landrum, Lisa M. ; Backes, Floor ; O’Cearbhaill, Roisin E. ; Al Baghdadi, Tareq ; Hill, Emily K. ; Thaker, Premal H. ; John, Veena S. ; Welch, Stephen ; Fader, Amanda N. ; Powell, Matthew A. ; Aghajanian, Carol
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-06, Vol.388 (23), p.2159-2170
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Novel Therapeutics in Ovarian Cancer: Expanding the Toolbox
Author / Creator:Moufarrij, Sara ; O’Cearbhaill, Roisin E.
Publisher:Switzerland: MDPI AG
Journal title:Current oncology (Toronto), 2023-12, Vol.31 (1), p.97-114
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Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results
Author / Creator:Hassan, Raffit ; Butler, Marcus ; O’Cearbhaill, Roisin E. ; Oh, David Y. ; Johnson, Melissa ; Zikaras, Kevin ; Smalley, Munisha ; Ross, Michael ; Tanyi, Janos L. ; Ghafoor, Azam ; Shah, Nirali N. ; Saboury, Babak ; Cao, Liang ; Quintás-Cardama, Alfonso ; Hong, David
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2023-08, Vol.29 (8), p.2099-2109
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Using PARP Inhibitors in Advanced Ovarian Cancer
Author / Creator:O'Cearbhaill, Roisin E
Publisher:United States: UBM LLC
Journal title:Oncology (Williston Park, N.Y.), 2018-07, Vol.32 (7), p.339-343
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Olaparib and α-specific PI3K inhibitor alpelisib for patients with epithelial ovarian cancer: a dose-escalation and dose-expansion phase 1b trial
Author / Creator:Konstantinopoulos, Panagiotis A ; Barry, William T ; Birrer, Michael ; Westin, Shannon N ; Cadoo, Karen A ; Shapiro, Geoffrey I ; Mayer, Erica L ; O'Cearbhaill, Roisin E ; Coleman, Robert L ; Kochupurakkal, Bose ; Whalen, Christin ; Curtis, Jennifer ; Farooq, Sarah ; Luo, Weixiu ; Eismann, Julia ; Buss, Mary K ; Aghajanian, Carol ; Mills, Gordon B ; Palakurthi, Sangeetha ; Kirschmeier, Paul ; Liu, Joyce ; Cantley, Lewis C ; Kaufmann, Scott H ; Swisher, Elizabeth M ; D'Andrea, Alan D ; Winer, Eric ; Wulf, Gerburg M ; Matulonis, Ursula A
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2019-04, Vol.20 (4), p.570-580
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Dual targeting ovarian cancer by Muc16 CAR T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1
Author / Creator:Mun, Sung Soo ; Meyerberg, Jeremy ; Peraro, Leila ; Korontsvit, Tatyana ; Gardner, Thomas ; Malviya, Manish ; Kyi, Chrisann ; O’Cearbhaill, Roisin E. ; Liu, Cheng ; Dao, Tao ; Scheinberg, David A.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2023-11, Vol.72 (11), p.3773-3786
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Nivolumab for mismatch-repair-deficient or hypermutated gynecologic cancers: a phase 2 trial with biomarker analyses
Author / Creator:Friedman, Claire F. ; Manning-Geist, Beryl L. ; Zhou, Qin ; Soumerai, Tara ; Holland, Aliya ; Da Cruz Paula, Arnaud ; Green, Hunter ; Ozsoy, Melih Arda ; Iasonos, Alexia ; Hollmann, Travis ; Leitao, Mario M. ; Mueller, Jennifer J. ; Makker, Vicky ; Tew, William P. ; O’Cearbhaill, Roisin E. ; Liu, Ying L. ; Rubinstein, Maria M. ; Troso-Sandoval, Tiffany ; Lichtman, Stuart M. ; Schram, Alison ; Kyi, Chrisann ; Grisham, Rachel N. ; Causa Andrieu, Pamela ; Wherry, E. John ; Aghajanian, Carol ; Weigelt, Britta ; Hensley, Martee L. ; Zamarin, Dmitriy
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2024-05, Vol.30 (5), p.1330-1338
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Phase I Study of a Multivalent WT1 Peptide Vaccine (Galinpepimut-S) in Combination with Nivolumab in Patients with WT1-Expressing Ovarian Cancer in Second or Third Remission
Author / Creator:Manning-Geist, Beryl L. ; Gnjatic, Sacha ; Aghajanian, Carol ; Konner, Jason ; Kim, Sarah H. ; Sarasohn, Debra ; Soldan, Krysten ; Tew, William P. ; Sarlis, Nicholas J. ; Zamarin, Dmitriy ; Kravetz, Sara ; Laface, Ilaria ; Rasalan-Ho, Teresa ; Qi, Jingjing ; Wong, Phillip ; Sabbatini, Paul J. ; O’Cearbhaill, Roisin E.
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2023-02, Vol.15 (5), p.1458
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ArticlesPeer ReviewedFull Text
Is It Time to Centralize Ovarian Cancer Care in the United States?
Author / Creator:Cowan, Renee A. ; O’Cearbhaill, Roisin E. ; Gardner, Ginger J. ; Levine, Douglas A. ; Long Roche, Kara ; Sonoda, Yukio ; Zivanovic, Oliver ; Tew, William P. ; Sala, Evis ; Lakhman, Yulia ; Vargas Alvarez, Hebert A. ; Sarasohn, Debra M. ; Mironov, Svetlana ; Abu-Rustum, Nadeem R. ; Chi, Dennis S.
Publisher:Cham: Springer International Publishing
Journal title:Annals of surgical oncology, 2016-03, Vol.23 (3), p.989-993
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International Study of Primary Mucinous Ovarian Carcinomas Managed at Tertiary Medical Centers
Author / Creator:Mueller, Jennifer J. ; Lajer, Henrik ; Mosgaard, Berit Jul ; Hamba, Slim Bach ; Morice, Philippe ; Gouy, Sebastien ; Hussein, Yaser ; Soslow, Robert A. ; Schlappe, Brooke A. ; Zhou, Qin C. ; lasonos, Alexia ; Høgdall, Claus ; Leary, Alexandra ; O’Cearbhaill, Roisin E. ; Abu-Rustum, Nadeem R.
Publisher:United States: Elsevier Inc
Journal title:International journal of gynecological cancer, 2018-06, Vol.28 (5), p.915-924
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Long-term outcomes of patients with recurrent ovarian cancer treated with a polyvalent vaccine with bevacizumab combination
Author / Creator:Kahn, Ryan M. ; Ragupathi, Govind ; Zhou, Qin C. ; Iasonos, Alexia ; Kravetz, Sara ; Hensley, Martee L. ; Konner, Jason A. ; Makker, Vicky ; Tew, William P. ; Aghajanian, Carol ; Sabbatini, Paul J. ; O’Cearbhaill, Roisin E.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2023-01, Vol.72 (1), p.183-191
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ArticlesPeer ReviewedFull Text
Safety, immunogenicity, and clinical efficacy of durvalumab in combination with folate receptor alpha vaccine TPIV200 in patients with advanced ovarian cancer: a phase II trial
Author / Creator:Zamarin, Dmitriy ; Walderich, Sven ; Holland, Aliya ; Zhou, Qin ; Iasonos, Alexia E ; Torrisi, Jean M ; Merghoub, Taha ; Chesebrough, Lewis F ; Mcdonnell, Autumn S ; Gallagher, Jacqueline M ; Li, Yanyun ; Hollmann, Travis J ; Grisham, Rachel N ; Erskine, Courtney L ; Block, Mathew S ; Knutson, Keith L ; O’Cearbhaill, Roisin E ; Aghajanian, Carol ; Konner, Jason A
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2020-06, Vol.8 (1), p.e000829
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Procedural interventions for oligoprogression during treatment with immune checkpoint blockade in gynecologic malignancies: a case series
Author / Creator:Sia, Tiffany Y ; Wan, Vivian ; Finlan, Michael ; Zhou, Qin C ; Iasonos, Alexia ; Zivanovic, Oliver ; Sonoda, Yukio ; Chi, Dennis S ; Long Roche, Kara ; Jewell, Elizabeth ; Tew, William P ; O'Cearbhaill, Roisin E ; Cohen, Seth ; Makker, Vicky ; Liu, Ying L ; Friedman, Claire F ; Kyi, Chrisann ; Zamarin, Dmitriy ; Gardner, Ginger
Publisher:England: BMJ Publishing Group Ltd
Journal title:International journal of gynecological cancer, 2024-04, Vol.34 (4), p.594-601
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Impact of tumor heterogeneity and microenvironment in identifying neoantigens in a patient with ovarian cancer
Author / Creator:Dao, Tao ; Klatt, Martin G. ; Korontsvit, Tatyana ; Mun, Sung Soo ; Guzman, Sean ; Mattar, Marissa ; Zivanovic, Oliver ; Kyi, Chrisann K. ; Socci, Nicholas D. ; O’Cearbhaill, Roisin E. ; Scheinberg, David A.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2021-05, Vol.70 (5), p.1189-1202
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A Randomized Trial of Prophylactic Extended Carboplatin Infusion to Reduce Hypersensitivity Reactions in Recurrent Ovarian Cancer
Author / Creator:LaVigne, Katherine ; Hyman, David M. ; Zhou, Qin C. ; Iasonos, Alexia ; Tew, William P. ; Aghajanian, Carol ; Makker, Vicky ; Hensley, Martee L. ; Konner, Jason ; Grisham, Rachel N. ; Cangemi, Nicholas ; Soldan, Krysten ; Spriggs, David R. ; Sabbatini, Paul J. ; O'Cearbhaill, Roisin E.
Publisher:United States: by the International Gynecologic Cancer Society and the European Society of Gynaecological Oncology
Journal title:International journal of gynecological cancer, 2018-07, Vol.28 (6), p.1176-1182
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Phase I dose escalation safety and feasibility study of autologous WT1-sensitized T cells for the treatment of patients with recurrent ovarian cancer
Author / Creator:Kyi, Chrisann ; Doubrovina, Ekaterina ; Zhou, Qin ; Kravetz, Sara ; Iasonos, Alexia ; Aghajanian, Carol ; Sabbatini, Paul ; Spriggs, David ; O'Reilly, Richard J ; O’Cearbhaill, Roisin E
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2021-08, Vol.9 (8), p.e002752
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ArticlesPeer ReviewedFull Text
Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer
Author / Creator:Eskander, Ramez N. ; Sill, Michael W. ; Beffa, Lindsey ; Moore, Richard G. ; Hope, Joanie M. ; Musa, Fernanda B. ; Mannel, Robert ; Shahin, Mark S. ; Cantuaria, Guilherme H. ; Girda, Eugenia ; Mathews, Cara ; Kavecansky, Juraj ; Leath, Charles A. ; Gien, Lilian T. ; Hinchcliff, Emily M. ; Lele, Shashikant B. ; Landrum, Lisa M. ; Backes, Floor ; O’Cearbhaill, Roisin E. ; Al Baghdadi, Tareq ; Hill, Emily K. ; Thaker, Premal H. ; John, Veena S. ; Welch, Stephen ; Fader, Amanda N. ; Powell, Matthew A. ; Aghajanian, Carol
Journal title:The New England journal of medicine, 2023-06, Vol.388 (23), p.2159-2170
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ArticlesPeer ReviewedFull Text
A Phase I Study of Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission
Author / Creator:O’Cearbhaill, Roisin ; Ragupathi, Govind ; Zhu, Jianglong ; Wan, Qian ; Mironov, Svetlana ; Yang, Guangbin ; Spassova, Maria ; Iasonos, Alexia ; Kravetz, Sara ; Ouerfelli, Ouathek ; Spriggs, David ; Danishefsky, Samuel ; Sabbatini, Paul
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2016-04, Vol.8 (4), p.46
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Prognostic Significance of the Number of Postoperative Intraperitoneal Chemotherapy Cycles for Patients With Advanced Epithelial Ovarian Cancer
Author / Creator:Suidan, Rudy S ; Zhou, Qin ; Iasonos, Alexia ; Roisin E O’Cearbhaill ; Chi, Dennis S ; Long Roche, Kara C ; Tanner, Edward J ; Denesopolis, John ; Barakat, Richard R ; Zivanovic, Oliver
Publisher:Kidlington: Elsevier Limited
Journal title:International journal of gynecological cancer, 2015-05, Vol.25 (4), p.599-606
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ArticlesPeer ReviewedFull Text
Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer
Author / Creator:González-Martín, Antonio ; Pothuri, Bhavana ; Vergote, Ignace ; DePont Christensen, René ; Graybill, Whitney ; Mirza, Mansoor R ; McCormick, Colleen ; Lorusso, Domenica ; Hoskins, Paul ; Freyer, Gilles ; Baumann, Klaus ; Jardon, Kris ; Redondo, Andrés ; Moore, Richard G ; Vulsteke, Christof ; O’Cearbhaill, Roisin E ; Lund, Bente ; Backes, Floor ; Barretina-Ginesta, Pilar ; Haggerty, Ashley F ; Rubio-Pérez, Maria J ; Shahin, Mark S ; Mangili, Giorgia ; Bradley, William H ; Bruchim, Ilan ; Sun, Kaiming ; Malinowska, Izabela A ; Li, Yong ; Gupta, Divya ; Monk, Bradley J
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-12, Vol.381 (25), p.2391-2402
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Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer

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Novel Therapeutics in Ovarian Cancer: Expanding the Toolbox

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Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results

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Using PARP Inhibitors in Advanced Ovarian Cancer

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Olaparib and α-specific PI3K inhibitor alpelisib for patients with epithelial ovarian cancer: a dose-escalation and dose-expansion phase 1b trial

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Dual targeting ovarian cancer by Muc16 CAR T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1

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Nivolumab for mismatch-repair-deficient or hypermutated gynecologic cancers: a phase 2 trial with biomarker analyses

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Phase I Study of a Multivalent WT1 Peptide Vaccine (Galinpepimut-S) in Combination with Nivolumab in Patients with WT1-Expressing Ovarian Cancer in Second or Third Remission

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Is It Time to Centralize Ovarian Cancer Care in the United States?

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International Study of Primary Mucinous Ovarian Carcinomas Managed at Tertiary Medical Centers

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Long-term outcomes of patients with recurrent ovarian cancer treated with a polyvalent vaccine with bevacizumab combination

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Safety, immunogenicity, and clinical efficacy of durvalumab in combination with folate receptor alpha vaccine TPIV200 in patients with advanced ovarian cancer: a phase II trial

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Procedural interventions for oligoprogression during treatment with immune checkpoint blockade in gynecologic malignancies: a case series

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Impact of tumor heterogeneity and microenvironment in identifying neoantigens in a patient with ovarian cancer

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A Randomized Trial of Prophylactic Extended Carboplatin Infusion to Reduce Hypersensitivity Reactions in Recurrent Ovarian Cancer

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Phase I dose escalation safety and feasibility study of autologous WT1-sensitized T cells for the treatment of patients with recurrent ovarian cancer

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Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer

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A Phase I Study of Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission

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Prognostic Significance of the Number of Postoperative Intraperitoneal Chemotherapy Cycles for Patients With Advanced Epithelial Ovarian Cancer

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Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer

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