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551 results for Oligonucleotides+-+metabolism

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ArticlesPeer ReviewedFull Text
Current Challenges in Delivery and Cytosolic Translocation of Therapeutic RNAs
Author / Creator:Johannes, Ludger ; Lucchino, Marco
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Nucleic acid therapeutics, 2018-06, Vol.28 (3), p.178-193
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Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability
Author / Creator:Assarsson, Erika ; Lundberg, Martin ; Holmquist, Göran ; Björkesten, Johan ; Bucht Thorsen, Stine ; Ekman, Daniel ; Eriksson, Anna ; Rennel Dickens, Emma ; Ohlsson, Sandra ; Edfeldt, Gabriella ; Andersson, Ann-Catrin ; Lindstedt, Patrik ; Stenvang, Jan ; Gullberg, Mats ; Fredriksson, Simon
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-04, Vol.9 (4), p.e95192-e95192
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ArticlesPeer ReviewedFull Text
Profiling surface proteins on individual exosomes using a proximity barcoding assay
Author / Creator:Wu, Di ; Yan, Junhong ; Shen, Xia ; Sun, Yu ; Thulin, Måns ; Cai, Yanling ; Wik, Lotta ; Shen, Qiujin ; Oelrich, Johan ; Qian, Xiaoyan ; Dubois, K. Louise ; Ronquist, K. Göran ; Nilsson, Mats ; Landegren, Ulf ; Kamali-Moghaddam, Masood
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-08, Vol.10 (1), p.3854-10, Article 3854
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Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood–brain barrier and knock down genes in the rodent CNS
Author / Creator:Nagata, Tetsuya ; Dwyer, Chrissa A. ; Yoshida-Tanaka, Kie ; Ihara, Kensuke ; Ohyagi, Masaki ; Kaburagi, Hidetoshi ; Miyata, Haruka ; Ebihara, Satoe ; Yoshioka, Kotaro ; Ishii, Takashi ; Miyata, Kanjiro ; Miyata, Kenichi ; Powers, Berit ; Igari, Tomoko ; Yamamoto, Syunsuke ; Arimura, Naoto ; Hirabayashi, Hideki ; Uchihara, Toshiki ; Hara, Rintaro Iwata ; Wada, Takeshi ; Bennett, C. Frank ; Seth, Punit P. ; Rigo, Frank ; Yokota, Takanori
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2021-12, Vol.39 (12), p.1529-1536
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Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer
Author / Creator:Costales, Matthew G. ; Aikawa, Haruo ; Li, Yue ; Childs-Disney, Jessica L. ; Abegg, Daniel ; Hoch, Dominic G. ; Velagapudi, Sai Pradeep ; Nakai, Yoshio ; Khan, Tanya ; Wang, Kye Won ; Yildirim, Ilyas ; Adibekian, Alexander ; Wang, Eric T. ; Disney, Matthew D.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (5), p.2406-2411
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ArticlesPeer ReviewedFull Text
Programmable RNA recognition and cleavage by CRISPR/Cas9
Author / Creator:O’Connell, Mitchell R. ; Oakes, Benjamin L. ; Sternberg, Samuel H. ; East-Seletsky, Alexandra ; Kaplan, Matias ; Doudna, Jennifer A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-12, Vol.516 (7530), p.263-266
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Phosphorothioates, Essential Components of Therapeutic Oligonucleotides
Author / Creator:Eckstein, Fritz
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Nucleic acid therapeutics, 2014-12, Vol.24 (6), p.374-387
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Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model
Author / Creator:Angelbello, Alicia J. ; Rzuczek, Suzanne G. ; Mckee, Kendra K. ; Chen, Jonathan L. ; Olafson, Hailey ; Cameron, Michael D. ; Moss, Walter N. ; Wang, Eric T. ; Disney, Matthew D.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (16), p.7799-7804
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Oligonucleotide-Mediated Genome Editing Provides Precision and Function to Engineered Nucleases and Antibiotics in Plants
Author / Creator:Sauer, Noel J. ; Narváez-Vásquez, Javier ; Mozoruk, Jerry ; Miller, Ryan B. ; Warburg, Zachary J. ; Woodward, Melody J. ; Mihiret, Yohannes A. ; Lincoln, Tracey A. ; Segami, Rosa E. ; Sanders, Steven L. ; Walker, Keith A. ; Beetham, Peter R. ; Schöpke, Christian R. ; Gocal, Greg F.W.
Publisher:United States: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2016-04, Vol.170 (4), p.1917-1928
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ArticlesPeer ReviewedFull Text
Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression
Author / Creator:Loyer, Xavier ; Paradis, Valérie ; Hénique, Carole ; Vion, Anne-Clémence ; Colnot, Nathalie ; Guerin, Coralie L ; Devue, Cécile ; On, Sissi ; Scetbun, Jérémy ; Romain, Mélissa ; Paul, Jean-Louis ; Rothenberg, Marc E ; Marcellin, Patrick ; Durand, François ; Bedossa, Pierre ; Prip-Buus, Carina ; Baugé, Eric ; Staels, Bart ; Boulanger, Chantal M ; Tedgui, Alain ; Rautou, Pierre-Emmanuel
Publisher:England: BMJ Publishing Group
Journal title:Gut, 2016-11, Vol.65 (11), p.1882-1894
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ArticlesPeer ReviewedFull Text
APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p
Author / Creator:Wang, Kun ; Liu, Cui-Yun ; Zhou, Lu-Yu ; Wang, Jian-Xun ; Wang, Man ; Zhao, Bing ; Zhao, Wen-Ke ; Xu, Shi-Jun ; Fan, Li-Hua ; Zhang, Xiao-Jie ; Feng, Chang ; Wang, Chao-Qun ; Zhao, Yan-Fang ; Li, Pei-Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-04, Vol.6 (1), p.6779-6779
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A new type of DNA phosphorothioation-based antiviral system in archaea
Author / Creator:Xiong, Lei ; Liu, Siyi ; Chen, Si ; Xiao, Yao ; Zhu, Bochen ; Gao, Yali ; Zhang, Yujing ; Chen, Beibei ; Luo, Jie ; Deng, Zixin ; Chen, Xiangdong ; Wang, Lianrong ; Chen, Shi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-04, Vol.10 (1), p.1688-11, Article 1688
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In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models
Author / Creator:Yin, Chaoran ; Zhang, Ting ; Qu, Xiying ; Zhang, Yonggang ; Putatunda, Raj ; Xiao, Xiao ; Li, Fang ; Xiao, Weidong ; Zhao, Huaqing ; Dai, Shen ; Qin, Xuebin ; Mo, Xianming ; Young, Won-Bin ; Khalili, Kamel ; Hu, Wenhui
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2017-05, Vol.25 (5), p.1168-1186
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Phosphorylated lipid-conjugated oligonucleotide selectively anchors on cell membranes with high alkaline phosphatase expression
Author / Creator:Jin, Cheng ; He, Jiaxuan ; Zou, Jianmei ; Xuan, Wenjing ; Fu, Ting ; Wang, Ruowen ; Tan, Weihong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-06, Vol.10 (1), p.2704-7, Article 2704
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Highly multiplexed single-cell RNA-seq by DNA oligonucleotide tagging of cellular proteins
Author / Creator:Gehring, Jase ; Hwee Park, Jong ; Chen, Sisi ; Thomson, Matthew ; Pachter, Lior
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2020-01, Vol.38 (1), p.35-38
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Bacterial cGAS senses a viral RNA to initiate immunity
Author / Creator:Banh, Dalton V. ; Roberts, Cameron G. ; Morales-Amador, Adrian ; Berryhill, Brandon A. ; Chaudhry, Waqas ; Levin, Bruce R. ; Brady, Sean F. ; Marraffini, Luciano A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-11, Vol.623 (7989), p.1001-1008
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CRMAGE: CRISPR Optimized MAGE Recombineering
Author / Creator:Ronda, Carlotta ; Pedersen, Lasse Ebdrup ; Sommer, Morten O. A. ; Nielsen, Alex Toftgaard
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-01, Vol.6 (1), p.19452, Article 19452
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Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression
Author / Creator:Zhang, Wen Cai ; Chin, Tan Min ; Yang, Henry ; Nga, Min En ; Lunny, Declan Patrick ; Lim, Edwin Kok Hao ; Sun, Li Li ; Pang, Yin Huei ; Leow, Yi Ning ; Malusay, Shanneen Rossellini Y ; Lim, Priscilla Xin Hui ; Lee, Jeravan Zili ; Tan, Benedict Jian Wei ; Shyh-Chang, Ng ; Lim, Elaine Hsuen ; Lim, Wan Teck ; Tan, Daniel Shao Weng ; Tan, Eng Huat ; Tai, Bee Choo ; Soo, Ross Andrew ; Tam, Wai Leong ; Lim, Bing
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-06, Vol.7 (1), p.11702-11702, Article 11702
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From SOMAmer-Based Biomarker Discovery to Diagnostic and Clinical Applications: A SOMAmer-Based, Streamlined Multiplex Proteomic Assay
Author / Creator:Kraemer, Stephan ; Vaught, Jonathan D. ; Bock, Christopher ; Gold, Larry ; Katilius, Evaldas ; Keeney, Tracy R. ; Kim, Nancy ; Saccomano, Nicholas A. ; Wilcox, Sheri K. ; Zichi, Dom ; Sanders, Glenn M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-10, Vol.6 (10), p.e26332-e26332
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Chemistry of Peptide-Oligonucleotide Conjugates: A Review
Author / Creator:Klabenkova, Kristina ; Fokina, Alesya ; Stetsenko, Dmitry
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-09, Vol.26 (17), p.5420
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Showing 1 to 20 of 551 results

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Current Challenges in Delivery and Cytosolic Translocation of Therapeutic RNAs

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Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability

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Profiling surface proteins on individual exosomes using a proximity barcoding assay

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Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood–brain barrier and knock down genes in the rodent CNS

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Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer

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Programmable RNA recognition and cleavage by CRISPR/Cas9

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Phosphorothioates, Essential Components of Therapeutic Oligonucleotides

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Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model

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Oligonucleotide-Mediated Genome Editing Provides Precision and Function to Engineered Nucleases and Antibiotics in Plants

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Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression

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APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p

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A new type of DNA phosphorothioation-based antiviral system in archaea

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In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models

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Phosphorylated lipid-conjugated oligonucleotide selectively anchors on cell membranes with high alkaline phosphatase expression

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Highly multiplexed single-cell RNA-seq by DNA oligonucleotide tagging of cellular proteins

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Bacterial cGAS senses a viral RNA to initiate immunity

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CRMAGE: CRISPR Optimized MAGE Recombineering

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Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression

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From SOMAmer-Based Biomarker Discovery to Diagnostic and Clinical Applications: A SOMAmer-Based, Streamlined Multiplex Proteomic Assay

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Chemistry of Peptide-Oligonucleotide Conjugates: A Review

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