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CD19‐CAR engineered NK‐92 cells are sufficient to overcome NK cell resistance in B‐cell malignancies
Author / Creator:Romanski, Annette ; Uherek, Christoph ; Bug, Gesine ; Seifried, Erhard ; Klingemann, Hans ; Wels, Winfried S. ; Ottmann, Oliver G. ; Tonn, Torsten
Publisher:England: John Wiley and Sons Inc
Journal title:Journal of cellular and molecular medicine, 2016-07, Vol.20 (7), p.1287-1294
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Nilotinib in Imatinib-Resistant CML and Philadelphia Chromosome–Positive ALL
Author / Creator:Kantarjian, Hagop ; Giles, Francis ; Wunderle, Lydia ; Bhalla, Kapil ; O'Brien, Susan ; Wassmann, Barbara ; Tanaka, Chiaki ; Manley, Paul ; Rae, Patricia ; Mietlowski, William ; Bochinski, Kathy ; Hochhaus, Andreas ; Griffin, James D ; Hoelzer, Dieter ; Albitar, Maher ; Dugan, Margaret ; Cortes, Jorge ; Alland, Leila ; Ottmann, Oliver G
Publisher:Boston, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2006-06, Vol.354 (24), p.2542-2551
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Differential Effects of Selective Inhibitors Targeting the PI3K/AKT/mTOR Pathway in Acute Lymphoblastic Leukemia
Author / Creator:Badura, Susanne ; Tesanovic, Tamara ; Pfeifer, Heike ; Wystub, Sylvia ; Nijmeijer, Bart A. ; Liebermann, Marcus ; Falkenburg, J. H. Frederik ; Ruthardt, Martin ; Ottmann, Oliver G.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-11, Vol.8 (11), p.e80070
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Bim and Bad Mediate Imatinib-Induced Killing of Bcr/Abl⁺ Leukemic Cells, and Resistance Due to Their Loss Is Overcome by a BH3 Mimetic
Author / Creator:Kuroda, Junya ; Puthalakath, Hamsa ; Cragg, Mark S. ; Kelly, Priscilla N. ; Bouillet, Philippe ; Huang, David C. S. ; Kimura, Shinya ; Ottmann, Oliver G. ; Druker, Brian J. ; Villunger, Andreas ; Roberts, Andrew W. ; Strasser, Andreas
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (40), p.14907-14912
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A phase I study of a dual PI3-kinase/mTOR inhibitor BEZ235 in adult patients with relapsed or refractory acute leukemia
Author / Creator:Lang, Fabian ; Wunderle, Lydia ; Badura, Susanne ; Schleyer, Eberhard ; Brüggemann, Monika ; Serve, Hubert ; Schnittger, Susanne ; Gökbuget, Nicola ; Pfeifer, Heike ; Wagner, Sebastian ; Ashelford, Kevin ; Bug, Gesine ; Ottmann, Oliver G.
Publisher:London: BioMed Central Ltd
Journal title:BMC pharmacology & toxicology, 2020-09, Vol.21 (1), p.1-14, Article 70
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ArticlesPeer ReviewedFull Text
Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia
Author / Creator:Baerlocher, Gabriela M ; Oppliger Leibundgut, Elisabeth ; Ottmann, Oliver G ; Spitzer, Gary ; Odenike, Olatoyosi ; McDevitt, Michael A ; Röth, Alexander ; Daskalakis, Michael ; Burington, Bart ; Stuart, Monic ; Snyder, David S
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2015-09, Vol.373 (10), p.920-928
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The effect of the dual Src/Abl kinase inhibitor AZD0530 on Philadelphia positive leukaemia cell lines
Author / Creator:Gwanmesia, Patricia Mambou ; Romanski, Annette ; Schwarz, Kerstin ; Bacic, Biserka ; Ruthardt, Martin ; Ottmann, Oliver G
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2009-02, Vol.9 (1), p.53-53, Article 53
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p53-independent anti-tumor effects of the nitrogen-containing bisphosphonate zoledronic acid
Author / Creator:Kuroda, Junya ; Kimura, Shinya ; Segawa, Hidekazu ; Sato, Kiyoshi ; Matsumoto, Seiji ; Nogawa, Masaki ; Yuasa, Takeshi ; Kobayashi, Yutaka ; Yoshikawa, Toshikazu ; Ottmann, Oliver G. ; Maekawa, Taira
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Cancer science, 2004-02, Vol.95 (2), p.186-192
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The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis
Author / Creator:Mian, Afsar A. ; Baumann, Ines ; Liebermann, Marcus ; Grebien, Florian ; Superti-Furga, Giulio ; Ruthardt, Martin ; Ottmann, Oliver G. ; Hantschel, Oliver
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2019-09, Vol.33 (9), p.2319-2323
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ArticlesPeer ReviewedFull Text
Inhibition of HIV-1 replication by small interfering RNAs directed against Glioma Pathogenesis Related Protein (GliPR) expression
Author / Creator:Capalbo, Gianni ; Müller-Kuller, Thea ; Dietrich, Ursula ; Hoelzer, Dieter ; Ottmann, Oliver G ; Scheuring, Urban J
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2010-03, Vol.7 (1), p.26-26, Article 26
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Antiproliferative Efficacy of the Third-Generation Bisphosphonate, Zoledronic Acid, Combined with Other Anticancer Drugs in Leukemic Cell Lines
Author / Creator:Kimura, Shinya ; Kuroda, Junya ; Segawa, Hidekazu ; Sato, Kiyoshi ; Nogawa, Masaki ; Yuasa, Takeshi ; Ottmann, Oliver G. ; Maekawa, Taira
Publisher:Tokyo: Springer
Journal title:International journal of hematology, 2004-01, Vol.79 (1), p.37-43
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Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia
Author / Creator:Giles, Francis J. ; Yin, Ophelia Q. P. ; Sallas, William M. ; le Coutre, Philipp D. ; Woodman, Richard C. ; Ottmann, Oliver G. ; Baccarani, Michele ; Kantarjian, Hagop M.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:European journal of clinical pharmacology, 2013-04, Vol.69 (4), p.813-823
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ArticlesPeer ReviewedFull Text
CD 19‐ CAR engineered NK ‐92 cells are sufficient to overcome NK cell resistance in B‐cell malignancies
Author / Creator:Romanski, Annette ; Uherek, Christoph ; Bug, Gesine ; Seifried, Erhard ; Klingemann, Hans ; Wels, Winfried S. ; Ottmann, Oliver G. ; Tonn, Torsten
Publisher:Chichester: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2016-07, Vol.20 (7), p.1287-1294
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Characterization of ZC3H15 as a potential TRAF-2-interacting protein implicated in the NFκB pathway and overexpressed in AML
Author / Creator:CAPALBO, GIANNI ; MUELLER-KULLER, THEA ; KOSCHMIEDER, STEFFEN ; KLEIN, HANS-ULRICH ; OTTMANN, OLIVER G ; HOELZER, DIETER ; SCHEURING, URBAN J
Publisher:Athens: D.A. Spandidos
Journal title:International journal of oncology, 2013-07, Vol.43 (1), p.246-254
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Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: a gene-expression study
Author / Creator:Hofmann, Wolf-K ; de Vos, Sven ; Elashoff, David ; Gschaidmeier, Harald ; Hoelzer, Dieter ; Koeffler, H Phillip ; Ottmann, Oliver G
Publisher:London: Elsevier Ltd
Journal title:The Lancet (British edition), 2002-02, Vol.359 (9305), p.481-486
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The DAC system and associations with acute leukemias and myelodysplastic syndromes
Author / Creator:Bug, Gesine ; Ottmann, Oliver G.
Publisher:Boston: Springer US
Journal title:Investigational new drugs, 2010-12, Vol.28 (Suppl 1), p.36-49
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Endoplasmic reticulum protein GliPR1 regulates G protein signaling and the cell cycle and is overexpressed in AML
Author / Creator:CAPALBO, GIANNI ; MUELLER-KULLER, THEA ; KOSCHMIEDER, STEFFEN ; KLEIN, HANS-ULRICH ; OTTMANN, OLIVER G ; HOELZER, DIETER ; SCHEURING, URBAN J
Publisher:Greece: D.A. Spandidos
Journal title:Oncology reports, 2013-11, Vol.30 (5), p.2254-2262
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Expression of interleukin-18 receptor in fibroblast-like synoviocytes
Author / Creator:Möller, Burkhard ; Kessler, Uta ; Rehart, Stefan ; Kalina, Uwe ; Ottmann, Oliver G ; Peter Kaltwasser, Joachim ; Hoelzer, Dieter ; Kukoc-Zivojnov, Natasa
Publisher:BioMed Central Ltd
Journal title:Arthritis research & therapy, 2002-01, Vol.4 (2), Article 139
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Treatment of poor-risk myelodysplastic syndromes and acute myeloid leukemia with a combination of 5-azacytidine and valproic acid
Author / Creator:Kuendgen, Andrea ; Bug, Gesine ; Ottmann, Oliver G. ; Haase, Detlef ; Schanz, Julie ; Hildebrandt, Barbara ; Nachtkamp, Kathrin ; Neukirchen, Judith ; Dienst, Ariane ; Haas, Rainer ; Germing, Ulrich ; Gattermann, Norbert
Publisher:Germany: Springer-Verlag
Journal title:Clinical epigenetics, 2011-08, Vol.2 (2), p.389-399
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Long-term results of a prospective randomized trial evaluating G-CSF priming in intensive induction chemotherapy followed by autologous stem cell transplantation in elderly patients with acute myeloid...
Author / Creator:Bug, Gesine ; Koschmieder, Steffen ; Krauter, Juergen ; Heuser, Michael ; Thol, Felicitas ; Wiebe, Stefanie ; Hofmann, Wolf-Karsten ; Klein, Stefan A. ; Wegener, Gerd ; Göhring, Gudrun ; Heit, Wolfgang ; Hoelzer, Dieter ; Ganser, Arnold ; Ottmann, Oliver G.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2014-02, Vol.93 (2), p.193-202
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Showing 1 to 20 of 30 results

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CD19‐CAR engineered NK‐92 cells are sufficient to overcome NK cell resistance in B‐cell malignancies

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Nilotinib in Imatinib-Resistant CML and Philadelphia Chromosome–Positive ALL

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Differential Effects of Selective Inhibitors Targeting the PI3K/AKT/mTOR Pathway in Acute Lymphoblastic Leukemia

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Bim and Bad Mediate Imatinib-Induced Killing of Bcr/Abl⁺ Leukemic Cells, and Resistance Due to Their Loss Is Overcome by a BH3 Mimetic

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A phase I study of a dual PI3-kinase/mTOR inhibitor BEZ235 in adult patients with relapsed or refractory acute leukemia

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Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia

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The effect of the dual Src/Abl kinase inhibitor AZD0530 on Philadelphia positive leukaemia cell lines

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p53-independent anti-tumor effects of the nitrogen-containing bisphosphonate zoledronic acid

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The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis

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Inhibition of HIV-1 replication by small interfering RNAs directed against Glioma Pathogenesis Related Protein (GliPR) expression

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Antiproliferative Efficacy of the Third-Generation Bisphosphonate, Zoledronic Acid, Combined with Other Anticancer Drugs in Leukemic Cell Lines

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Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia

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CD 19‐ CAR engineered NK ‐92 cells are sufficient to overcome NK cell resistance in B‐cell malignancies

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Characterization of ZC3H15 as a potential TRAF-2-interacting protein implicated in the NFκB pathway and overexpressed in AML

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Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: a gene-expression study

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The DAC system and associations with acute leukemias and myelodysplastic syndromes

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Endoplasmic reticulum protein GliPR1 regulates G protein signaling and the cell cycle and is overexpressed in AML

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Expression of interleukin-18 receptor in fibroblast-like synoviocytes

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Treatment of poor-risk myelodysplastic syndromes and acute myeloid leukemia with a combination of 5-azacytidine and valproic acid

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Long-term results of a prospective randomized trial evaluating G-CSF priming in intensive induction chemotherapy followed by autologous stem cell transplantation in elderly patients with acute myeloid...

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