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ArticlesPeer ReviewedFull Text
PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically
Author / Creator:Dickey, Audrey S ; Pineda, Victor V ; Tsunemi, Taiji ; Liu, Patrick P ; Miranda, Helen C ; Gilmore-Hall, Stephen K ; Lomas, Nicole ; Sampat, Kunal R ; Buttgereit, Anne ; Torres, Mark-Joseph Manalang ; Flores, April L ; Arreola, Martin ; Arbez, Nicolas ; Akimov, Sergey S ; Gaasterland, Terry ; Lazarowski, Eduardo R ; Ross, Christopher A ; Yeo, Gene W ; Sopher, Bryce L ; Magnuson, Gavin K ; Pinkerton, Anthony B ; Masliah, Eliezer ; La Spada, Albert R
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-01, Vol.22 (1), p.37-45
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METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARδ-dependent pathways in skeletal muscle of mice
Author / Creator:Jung, Tae Woo ; Lee, Sung Hoon ; Kim, Hyoung-Chun ; Bang, Joon Seok ; Abd El-Aty, A. M. ; Hacımüftüoğlu, Ahmet ; Shin, Yong Kyoo ; Jeong, Ji Hoon
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2018, 50(0), , pp.1-11
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PPARδ is a regulator of autophagy by its phosphorylation
Author / Creator:Gou, Qian ; Jiang, Yidan ; Zhang, Runyun ; Xu, Ying ; Xu, Huihui ; Zhang, Wenbo ; Shi, Juanjuan ; Hou, Yongzhong
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-06, Vol.39 (25), p.4844-4853
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PPARδ-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis
Author / Creator:Takata, Yasunori ; Liu, Joey ; Yin, Fen ; Collins, Alan R ; Lyon, Christopher J ; Lee, Chih-Hao ; Atkins, Annette R ; Downes, Michael ; Barish, Grant D ; Evans, Ronald M ; Hsueh, Willa A ; Tangirala, Rajendra K
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (11), p.4277-4282
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A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
Author / Creator:Ito, Keisuke ; Carracedo, Arkaitz ; Weiss, Dror ; Arai, Fumio ; Ala, Ugo ; Avigan, David E ; Schafer, Zachary T ; Evans, Ronald M ; Suda, Toshio ; Lee, Chih-Hao ; Pandolfi, Pier Paolo
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2012-09, Vol.18 (9), p.1350-1358
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PPAR[delta] is a regulator of autophagy by its phosphorylation
Author / Creator:Gou, Qian ; Jiang, Yidan ; Zhang, Runyun ; Xu, Ying ; Xu, Huihui ; Zhang, Wenbo ; Shi, Juanjuan
Publisher:Nature Publishing Group
Journal title:Oncogene, 2020-06, Vol.39 (25), p.4844
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PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance
Author / Creator:Mukundan, Lata ; Odegaard, Justin I ; Morel, Christine R ; Heredia, Jose E ; Mwangi, Julia W ; Ricardo-Gonzalez, Roberto R ; Goh, Y P Sharon ; Eagle, Alex Red ; Dunn, Shannon E ; Awakuni, Jennifer U H ; Nguyen, Khoa D ; Steinman, Lawrence ; Michie, Sara A ; Chawla, Ajay
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2009-11, Vol.15 (11), p.1266-1272
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Selective PPAR-Delta/PPAR-Gamma Activation Improves Cognition in a Model of Alzheimer’s Disease
Author / Creator:Steinke, Ian ; Govindarajulu, Manoj ; Pinky, Priyanka Das ; Bloemer, Jenna ; Yoo, Sieun ; Ward, Tracey ; Schaedig, Taylor ; Young, Taylor ; Wibowo, Fajar Setyo ; Suppiramaniam, Vishnu ; Amin, Rajesh H.
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2023-04, Vol.12 (8), p.1116
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PPARδ Regulates Glucose Metabolism and Insulin Sensitivity
Author / Creator:Lee, Chih-Hao ; Olson, Peter ; Hevener, Andrea ; Mehl, Isaac ; Chong, Ling-Wa ; Olefsky, Jerrold M. ; Gonzalez, Frank J. ; Ham, Jungyeob ; Kang, Heonjoong ; Peters, Jeffrey M. ; Evans, Ronald M.
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (9), p.3444-3449
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Discovering highly selective and diverse PPAR-delta agonists by ligand based machine learning and structural modeling
Author / Creator:Da’adoosh, Benny ; Marcus, David ; Rayan, Anwar ; King, Fred ; Che, Jianwei ; Goldblum, Amiram
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-01, Vol.9 (1), p.1106-1106, Article 1106
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ArticlesPeer ReviewedFull Text
PPAR-delta modulates membrane cholesterol and cytokine signaling in malignant B cells
Author / Creator:Sun, L ; Shi, Y ; Wang, G ; Wang, X ; Zeng, S ; Dunn, S E ; Fairn, G D ; Li, Y-J ; Spaner, D E
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2018-01, Vol.32 (1), p.184-193
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PPAR-delta promotes survival of chronic lymphocytic leukemia cells in energetically unfavorable conditions
Author / Creator:Li, Y-J ; Sun, L ; Shi, Y ; Wang, G ; Wang, X ; Dunn, S E ; Iorio, C ; Screaton, R A ; Spaner, D E
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2017-09, Vol.31 (9), p.1905-1914
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PPARδ attenuates hepatic steatosis through autophagy-mediated fatty acid oxidation
Author / Creator:Tong, Lei ; Wang, Long ; Yao, Shuangshuang ; Jin, Lina ; Yang, Jian ; Zhang, Yifei ; Ning, Guang ; Zhang, Zhiguo
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-02, Vol.10 (3), p.197-197, Article 197
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PPAR delta: a dagger in the heart of the metabolic syndrome
Author / Creator:Barish, Grant D ; Narkar, Vihang A ; Evans, Ronald M
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2006-03, Vol.116 (3), p.590-597
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Wnt/β-catenin Pathway-Mediated PPARδ Expression during Embryonic Development Differentiation and Disease
Author / Creator:Sidrat, Tabinda ; Rehman, Zia-Ur ; Joo, Myeong-Don ; Lee, Kyeong-Lim ; Kong, Il-Keun
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2021-02, Vol.22 (4), p.1854
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ArticlesPeer ReviewedFull Text
Cinnamic acid alleviates endothelial dysfunction and oxidative stress by targeting PPAR[delta] in obesity and diabetes
Author / Creator:Bai, Yizhen ; Tan, Dechao ; Deng, Qiaowen ; Miao, Lingchao ; Wang, Yuehan ; Zhou, Yan ; Yang, Yifan ; Wang, Shengpeng ; Vong, Chi Teng ; Cheang, Wai San
Publisher:BioMed Central Ltd
Journal title:Chinese medicine, 2025-01, Vol.20 (1)
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Fasting upregulates the monocarboxylate transporter MCT1 at the rat blood-brain barrier through PPAR [delta] activation
Author / Creator:Chasseigneaux, Stéphanie ; Cochois-Guégan, Véronique ; Lecorgne, Lucas ; Lochus, Murielle ; Nicolic, Sophie ; Blugeon, Corinne ; Jourdren, Laurent ; Gomez-Zepeda, David ; Tenzer, Stefan ; Sanquer, Sylvia ; Nivet-Antoine, Valérie ; Menet, Marie-Claude ; Laplanche, Jean-Louis ; Declèves, Xavier ; Cisternino, Salvatore ; Saubaméa, Bruno
Publisher:BioMed Central Ltd
Journal title:Fluids and barriers of the CNS, 2024-04, Vol.21 (1)
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Ligand-activated PPAR[delta] expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathway
Author / Creator:Han, Wei ; Wang, Nan ; Kong, Rui ; Bao, Wen ; Lu, Jie
Publisher:BioMed Central Ltd
Journal title:Journal of translational medicine, 2022-02, Vol.20 (1)
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Regulation of Muscle Fiber Type and Running Endurance by PPARδ
Author / Creator:Wang, Yong-Xu ; Zhang, Chun-Li ; Yu, Ruth T ; Cho, Helen K ; Nelson, Michael C ; Bayuga-Ocampo, Corinne R ; Ham, Jungyeob ; Kang, Heonjoong ; Evans, Ronald M
Publisher:San Francisco, USA: Public Library of Science
Journal title:PLoS biology, 2004-10, Vol.2 (10), p.e294
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PPARγ and PPARδ Negatively Regulate Specific Subsets of Lipopolysaccharide and IFN-γ Target Genes in Macrophages
Author / Creator:Welch, John S. ; Ricote, Mercedes ; Akiyama, Taro E. ; Gonzalez, Frank J. ; Glass, Christopher K.
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2003-05, Vol.100 (11), p.6712-6717
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Showing 1 to 20 of 1,586 results

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PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically

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METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARδ-dependent pathways in skeletal muscle of mice

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PPARδ is a regulator of autophagy by its phosphorylation

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PPARδ-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis

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A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

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PPAR[delta] is a regulator of autophagy by its phosphorylation

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PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance

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Selective PPAR-Delta/PPAR-Gamma Activation Improves Cognition in a Model of Alzheimer’s Disease

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PPARδ Regulates Glucose Metabolism and Insulin Sensitivity

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Discovering highly selective and diverse PPAR-delta agonists by ligand based machine learning and structural modeling

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PPAR-delta modulates membrane cholesterol and cytokine signaling in malignant B cells

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PPAR-delta promotes survival of chronic lymphocytic leukemia cells in energetically unfavorable conditions

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PPARδ attenuates hepatic steatosis through autophagy-mediated fatty acid oxidation

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PPAR delta: a dagger in the heart of the metabolic syndrome

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Wnt/β-catenin Pathway-Mediated PPARδ Expression during Embryonic Development Differentiation and Disease

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Cinnamic acid alleviates endothelial dysfunction and oxidative stress by targeting PPAR[delta] in obesity and diabetes

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Fasting upregulates the monocarboxylate transporter MCT1 at the rat blood-brain barrier through PPAR [delta] activation

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Ligand-activated PPAR[delta] expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathway

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Regulation of Muscle Fiber Type and Running Endurance by PPARδ

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PPARγ and PPARδ Negatively Regulate Specific Subsets of Lipopolysaccharide and IFN-γ Target Genes in Macrophages

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