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Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors
Author / Creator:Osipiuk, Jerzy ; Azizi, Saara-Anne ; Dvorkin, Steve ; Endres, Michael ; Jedrzejczak, Robert ; Jones, Krysten A. ; Kang, Soowon ; Kathayat, Rahul S. ; Kim, Youngchang ; Lisnyak, Vladislav G. ; Maki, Samantha L. ; Nicolaescu, Vlad ; Taylor, Cooper A. ; Tesar, Christine ; Zhang, Yu-An ; Zhou, Zhiyao ; Randall, Glenn ; Michalska, Karolina ; Snyder, Scott A. ; Dickinson, Bryan C. ; Joachimiak, Andrzej
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.743-9, Article 743
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Papain-like cysteine proteases as hubs in plant immunity
Author / Creator:Misas‐Villamil, Johana C. ; Hoorn, Renier A. L. ; Doehlemann, Gunther
Publisher:England: New Phytologist Trust
Journal title:The New phytologist, 2016-12, Vol.212 (4), p.902-907
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Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2
Author / Creator:Sanders, Brian C. ; Pokhrel, Suman ; Labbe, Audrey D. ; Mathews, Irimpan I. ; Cooper, Connor J. ; Davidson, Russell B. ; Phillips, Gwyndalyn ; Weiss, Kevin L. ; Zhang, Qiu ; O’Neill, Hugh ; Kaur, Manat ; Schmidt, Jurgen G. ; Reichard, Walter ; Surendranathan, Surekha ; Parvathareddy, Jyothi ; Phillips, Lexi ; Rainville, Christopher ; Sterner, David E. ; Kumaran, Desigan ; Andi, Babak ; Babnigg, Gyorgy ; Moriarty, Nigel W. ; Adams, Paul D. ; Joachimiak, Andrzej ; Hurst, Brett L. ; Kumar, Suresh ; Butt, Tauseef R. ; Jonsson, Colleen B. ; Ferrins, Lori ; Wakatsuki, Soichi ; Galanie, Stephanie ; Head, Martha S. ; Parks, Jerry M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-03, Vol.14 (1), p.1733-1733, Article 1733
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Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization
Author / Creator:Rehm, Fabian B. H. ; Jackson, Mark A. ; De Geyter, Ewout ; Yap, Kuok ; Gilding, Edward K. ; Durek, Thomas ; Craik, David J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (16), p.7831-7836
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Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin
Author / Creator:Wydorski, Pawel M. ; Osipiuk, Jerzy ; Lanham, Benjamin T. ; Tesar, Christine ; Endres, Michael ; Engle, Elizabeth ; Jedrzejczak, Robert ; Mullapudi, Vishruth ; Michalska, Karolina ; Fidelis, Krzysztof ; Fushman, David ; Joachimiak, Andrzej ; Joachimiak, Lukasz A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-04, Vol.14 (1), p.2366-2366, Article 2366
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In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular Docking, ADMET, Toxicity and DFT Studies
Author / Creator:Alesawy, Mohamed S ; Elkaeed, Eslam B ; Alsfouk, Aisha A ; Metwaly, Ahmed M ; Eissa, Ibrahim H
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-10, Vol.26 (21), p.6593
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Anti-Oxidative and Anti-Aging Activities of Porcine By-Product Collagen Hydrolysates Produced by Commercial Proteases: Effect of Hydrolysis and Ultrafiltration
Author / Creator:Hong, Geun-Pyo ; Min, Sang-Gi ; Jo, Yeon-Ji
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-03, Vol.24 (6), p.1104
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Enzymatic production of bioactive peptides from scotta, an exhausted by-product of ricotta cheese processing
Author / Creator:Monari, Stefania ; Ferri, Maura ; Russo, Claudio ; Prandi, Barbara ; Tedeschi, Tullia ; Bellucci, Paolo ; Zambrini, Angelo Vittorio ; Donati, Emanuela ; Tassoni, Annalisa
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-12, Vol.14 (12), p.e0226834-e0226834
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Autophagy is induced by swine acute diarrhea syndrome coronavirus through the cellular IRE1-JNK-Beclin 1 signaling pathway after an interaction of viral membrane-associated papain-like protease and GR...
Author / Creator:Shi, Da ; Zhou, Ling ; Shi, Hongyan ; Zhang, Jiyu ; Zhang, Jialin ; Zhang, Liaoyuan ; Liu, Dakai ; Feng, Tingshuai ; Zeng, Miaomiao ; Chen, Jianfei ; Zhang, Xin ; Xue, Mei ; Jing, Zhaoyang ; Liu, Jianbo ; Ji, Zhaoyang ; He, Haojie ; Guo, Longjun ; Wu, Yang ; Ma, Jingyun ; Feng, Li
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-03, Vol.19 (3), p.e1011201-e1011201
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Use of Different Proteases to Obtain Flaxseed Protein Hydrolysates with Antioxidant Activity
Author / Creator:Karamać, Magdalena ; Kosińska-Cagnazzo, Agnieszka ; Kulczyk, Anna
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2016-07, Vol.17 (7), p.1027-1027
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An in-vitro evaluation of residual dentin retained after using novel enzymatic-based chemomechanical caries removal agents
Author / Creator:Al-Badri, Huda ; Al-Taee, Lamis A. ; Banerjee, Avijit ; Al-Shammaree, Shatha A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-08, Vol.14 (1), p.19223-12, Article 19223
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Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site
Author / Creator:van Vliet, Vera J E ; Huynh, Nhan ; Palà, Judith ; Patel, Ankoor ; Singer, Alex ; Slater, Cole ; Chung, Jacky ; van Huizen, Mariska ; Teyra, Joan ; Miersch, Shane ; Luu, Gia-Khanh ; Ye, Wei ; Sharma, Nitin ; Ganaie, Safder S ; Russell, Raquel ; Chen, Chao ; Maynard, Mindy ; Amarasinghe, Gaya K ; Mark, Brian L ; Kikkert, Marjolein ; Sidhu, Sachdev S
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2022-12, Vol.18 (12), p.e1011065-e1011065
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Various Options for Covalent Immobilization of Cysteine Proteases-Ficin, Papain, Bromelain
Author / Creator:Holyavka, Marina G ; Goncharova, Svetlana S ; Artyukhov, Valeriy G
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-01, Vol.26 (2), p.547
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Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo
Author / Creator:van Huizen, Mariska ; Bloeme-Ter Horst, Jonna R ; de Gruyter, Heidi L M ; Geurink, Paul P ; van der Heden van Noort, Gerbrand J ; Knaap, Robert C M ; Nelemans, Tessa ; Ogando, Natacha S ; Leijs, Anouk A ; Urakova, Nadya ; Mark, Brian L ; Snijder, Eric J ; Myeni, Sebenzile K ; Kikkert, Marjolein
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-03, Vol.20 (3), p.e1012100-e1012100
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Origin and Early Diversification of the Papain Family of Cysteine Peptidases
Author / Creator:Kordiš, Dušan ; Turk, Vito
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-07, Vol.24 (14), p.11761
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Complexation of Bromelain, Ficin, and Papain with the Graft Copolymer of Carboxymethyl Cellulose Sodium Salt and N -Vinylimidazole Enhances Enzyme Proteolytic Activity
Author / Creator:Sorokin, Andrey V ; Goncharova, Svetlana S ; Lavlinskaya, Maria S ; Holyavka, Marina G ; Faizullin, Dzhigangir A ; Zuev, Yuriy F ; Kondratyev, Maxim S ; Artyukhov, Valeriy G
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-07, Vol.24 (14), p.11246
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Giant magnetoresistive biosensors for real-time quantitative detection of protease activity
Author / Creator:Adem, Sandeep ; Jain, Sonal ; Sveiven, Michael ; Zhou, Xiahan ; O’Donoghue, Anthony J. ; Hall, Drew A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-05, Vol.10 (1), p.7941, Article 7941
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Degradation Products of Extracellular Matrix Affect Cell Migration and Proliferation
Author / Creator:Reing, Janet E. ; Zhang, Li ; Myers-Irvin, Julie ; Cordero, Kevin E. ; Freytes, Donald O. ; Heber-Katz, Ellen ; Bedelbaeva, Khamilia ; McIntosh, Donna ; Dewilde, Abiche ; Braunhut, Susan J. ; Badylak, Stephen F.
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Tissue engineering. Part A, 2009-03, Vol.15 (3), p.65-614
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Enzymatic Hydrolysis Optimization of Yak Whey Protein Concentrates and Bioactivity Evaluation of the Ultrafiltered Peptide Fractions
Author / Creator:Hao, Lingshen ; Li, Xuefei ; Zhao, Baotang ; Song, Xuemei ; Zhang, Yan ; Liang, Qi
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-03, Vol.29 (6), p.1403
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Porcine placenta hydrolysate as an alternate functional food ingredient: In vitro antioxidant and antibacterial assessments
Author / Creator:Laosam, Phanthipha ; Panpipat, Worawan ; Yusakul, Gorawit ; Cheong, Ling-Zhi ; Chaijan, Manat
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-10, Vol.16 (10), p.e0258445
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Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors

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Papain-like cysteine proteases as hubs in plant immunity

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Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2

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Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization

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Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin

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In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular Docking, ADMET, Toxicity and DFT Studies

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Anti-Oxidative and Anti-Aging Activities of Porcine By-Product Collagen Hydrolysates Produced by Commercial Proteases: Effect of Hydrolysis and Ultrafiltration

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Enzymatic production of bioactive peptides from scotta, an exhausted by-product of ricotta cheese processing

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Autophagy is induced by swine acute diarrhea syndrome coronavirus through the cellular IRE1-JNK-Beclin 1 signaling pathway after an interaction of viral membrane-associated papain-like protease and GR...

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Use of Different Proteases to Obtain Flaxseed Protein Hydrolysates with Antioxidant Activity

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An in-vitro evaluation of residual dentin retained after using novel enzymatic-based chemomechanical caries removal agents

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Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site

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Various Options for Covalent Immobilization of Cysteine Proteases-Ficin, Papain, Bromelain

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Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo

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Origin and Early Diversification of the Papain Family of Cysteine Peptidases

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Complexation of Bromelain, Ficin, and Papain with the Graft Copolymer of Carboxymethyl Cellulose Sodium Salt and N -Vinylimidazole Enhances Enzyme Proteolytic Activity

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Giant magnetoresistive biosensors for real-time quantitative detection of protease activity

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Degradation Products of Extracellular Matrix Affect Cell Migration and Proliferation

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Enzymatic Hydrolysis Optimization of Yak Whey Protein Concentrates and Bioactivity Evaluation of the Ultrafiltered Peptide Fractions

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Porcine placenta hydrolysate as an alternate functional food ingredient: In vitro antioxidant and antibacterial assessments

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