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α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease
Author / Creator:Ludtmann, Marthe H. R. ; Angelova, Plamena R. ; Horrocks, Mathew H. ; Choi, Minee L. ; Rodrigues, Margarida ; Baev, Artyom Y. ; Berezhnov, Alexey V. ; Yao, Zhi ; Little, Daniel ; Banushi, Blerida ; Al-Menhali, Afnan Saleh ; Ranasinghe, Rohan T. ; Whiten, Daniel R. ; Yapom, Ratsuda ; Dolt, Karamjit Singh ; Devine, Michael J. ; Gissen, Paul ; Kunath, Tilo ; Jaganjac, Morana ; Pavlov, Evgeny V. ; Klenerman, David ; Abramov, Andrey Y. ; Gandhi, Sonia
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-06, Vol.9 (1), p.2293-16, Article 2293
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Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation
Author / Creator:Angelova, Plamena R. ; Choi, Minee L. ; Berezhnov, Alexey V. ; Horrocks, Mathew H. ; Hughes, Craig D. ; De, Suman ; Rodrigues, Margarida ; Yapom, Ratsuda ; Little, Daniel ; Dolt, Karamjit S. ; Kunath, Tilo ; Devine, Michael J. ; Gissen, Paul ; Shchepinov, Mikhail S. ; Sylantyev, Sergiy ; Pavlov, Evgeny V. ; Klenerman, David ; Abramov, Andrey Y. ; Gandhi, Sonia
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2020-10, Vol.27 (10), p.2781-2796
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The mitochondrial permeability transition phenomenon elucidated by cryo-EM reveals the genuine impact of calcium overload on mitochondrial structure and function
Author / Creator:Strubbe-Rivera, Jasiel O. ; Schrad, Jason R. ; Pavlov, Evgeny V. ; Conway, James F. ; Parent, Kristin N. ; Bazil, Jason N.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-01, Vol.11 (1), p.1037-15, Article 1037
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Tamoxifen-induced knockdown of the mitochondrial calcium uniporter in Thy1-expressing neurons protects mice from hypoxic/ischemic brain injury
Author / Creator:Nichols, Matthew ; Pavlov, Evgeny V. ; Robertson, George S.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2018-05, Vol.9 (6), p.606-11, Article 606
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C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition
Author / Creator:Amodeo, Giuseppe Federico ; Lee, Brenda Yasie ; Krilyuk, Natalya ; Filice, Carina Teresa ; Valyuk, Denis ; Otzen, Daniel Erik ; Noskov, Sergey ; Leonenko, Zoya ; Pavlov, Evgeny V.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-04, Vol.11 (1), p.8744-10, Article 8744
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Refractive Index Imaging Reveals That Elimination of the ATP Synthase C Subunit Does Not Prevent the Adenine Nucleotide Translocase-Dependent Mitochondrial Permeability Transition
Author / Creator:Neginskaya, Maria A. ; Morris, Sally E. ; Pavlov, Evgeny V.
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2023-07, Vol.12 (15), p.1950
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Mitochondrial Cyclosporine A-Independent Palmitate/Ca2+-Induced Permeability Transition Pore (PA-mPT Pore) and Its Role in Mitochondrial Function and Protection against Calcium Overload and Glutamate...
Author / Creator:Mironova, Galina D. ; Pavlov, Evgeny V.
Publisher:Basel: MDPI AG
Journal title:Cells (Basel, Switzerland), 2021-01, Vol.10 (1), p.125
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From ATP synthase dimers to C-ring conformational changes: unified model of the mitochondrial permeability transition pore
Author / Creator:Amodeo, Giuseppe Federico ; Solesio, Maria E. ; Pavlov, Evgeny V.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2017-12, Vol.8 (12), p.1-3, Article 1
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Polyhydroxybutyrate Targets Mammalian Mitochondria and Increases Permeability of Plasmalemmal and Mitochondrial Membranes
Author / Creator:Elustondo, Pia A. ; Angelova, Plamena R. ; Kawalec, Michał ; Michalak, Michał ; Kurcok, Piotr ; Abramov, Andrey Y. ; Pavlov, Evgeny V.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-09, Vol.8 (9), p.e75812
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Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels
Author / Creator:Stotz, Stephanie C ; Scott, Lucas OM ; Drummond-Main, Christopher ; Avchalumov, Yosef ; Girotto, Fernando ; Davidsen, Jörn ; Gómez-Gárcia, Maria R ; Rho, Jong M ; Pavlov, Evgeny V ; Colicos, Michael A
Publisher:England: BioMed Central Ltd
Journal title:Molecular brain, 2014-05, Vol.7 (1), p.42-42, Article 42
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Formation of High-Conductive C Subunit Channels upon Interaction with Cyclophilin D
Author / Creator:Amodeo, Giuseppe Federico ; Krilyuk, Natalya ; Pavlov, Evgeny V.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-10, Vol.22 (20), p.11022
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Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity
Author / Creator:Solesio, María E. ; Peixoto, Pablo M. ; Debure, Ludovic ; Madamba, Stephen M. ; de Leon, Mony J. ; Wisniewski, Thomas ; Pavlov, Evgeny V. ; Fossati, Silvia
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2018-08, Vol.17 (4), p.e12787-n/a
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ArticlesPeer ReviewedFull Text
Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex
Author / Creator:Mnatsakanyan, Nelli ; Park, Han-A ; Wu, Jing ; He, Xiang ; Llaguno, Marc C. ; Latta, Maria ; Miranda, Paige ; Murtishi, Besnik ; Graham, Morven ; Weber, Joachim ; Levy, Richard J. ; Pavlov, Evgeny V. ; Jonas, Elizabeth A.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2022-09, Vol.29 (9), p.1874-1887
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ArticlesPeer ReviewedFull Text
Mitochondrial Ca2+ uptake pathways
Author / Creator:Elustondo, Pia A. ; Nichols, Matthew ; Robertson, George S. ; Pavlov, Evgeny V.
Publisher:New York: Springer US
Journal title:Journal of bioenergetics and biomembranes, 2017-02, Vol.49 (1), p.113-119
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ArticlesPeer ReviewedFull Text
Correction: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation
Author / Creator:Angelova, Plamena R. ; Choi, Minee L. ; Berezhnov, Alexey V. ; Horrocks, Mathew H. ; Hughes, Craig D. ; De, Suman ; Rodrigues, Margarida ; Yapom, Ratsuda ; Little, Daniel ; Dolt, Karamjit S. ; Kunath, Tilo ; Devine, Michael J. ; Gissen, Paul ; Shchepinov, Mikhail S. ; Sylantyev, Sergiy ; Pavlov, Evgeny V. ; Klenerman, David ; Abramov, Andrey Y. ; Gandhi, Sonia
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2021-05, Vol.28 (5), p.1755-1755
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ArticlesPeer ReviewedFull Text
Correction: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation
Author / Creator:Angelova, Plamena R. ; Choi, Minee L. ; Berezhnov, Alexey V. ; Horrocks, Mathew H. ; Hughes, Craig D. ; De, Suman ; Rodrigues, Margarida ; Yapom, Ratsuda ; Little, Daniel ; Dolt, Karamjit S. ; Kunath, Tilo ; Devine, Michael J. ; Gissen, Paul ; Shchepinov, Mikhail S. ; Sylantyev, Sergiy ; Pavlov, Evgeny V. ; Klenerman, David ; Abramov, Andrey Y. ; Gandhi, Sonia
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2020-09, Vol.27 (9), p.2747-2747
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MAC inhibitors antagonize the pro-apoptotic effects of tBid and disassemble Bax / Bak oligomers
Author / Creator:Peixoto, Pablo M. ; Teijido, Oscar ; Mirzalieva, Oygul ; Dejean, Laurent M. ; Pavlov, Evgeny V. ; Antonsson, Bruno ; Kinnally, Kathleen W.
Publisher:New York: Springer US
Journal title:Journal of bioenergetics and biomembranes, 2017-02, Vol.49 (1), p.65-74
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ArticlesPeer ReviewedFull Text
Mitochondrial Cyclosporine A-Independent Palmitate/Ca 2+ -Induced Permeability Transition Pore (PA-mPT Pore) and Its Role in Mitochondrial Function and Protection against Calcium Overload and Glutamat...
Author / Creator:Mironova, Galina D ; Pavlov, Evgeny V
Publisher:Switzerland
Journal title:Cells (Basel, Switzerland), 2021-01, Vol.10 (1)
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C subunit of the ATP synthase is an amyloidogenic channel-forming peptide: possible implications in mitochondrial pathogenesis
Author / Creator:Amodeo, Giuseppe Federico ; Lee, Brenda Yasie ; Krilyuk, Natalya ; Filice, Carina Teresa ; Valyuk, Denis ; Otzen, Daniel ; Noskov, Sergei ; Leonenko, Zoya ; Pavlov, Evgeny V
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-01
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ArticlesPeer ReviewedFull Text
Mitochondrial Ca^sup 2+^ uptake pathways
Author / Creator:Elustondo, Pia A ; Nichols, Matthew ; Robertson, George S ; Pavlov, Evgeny V
Publisher:New York: Springer Nature B.V
Journal title:Journal of bioenergetics and biomembranes, 2017-02, Vol.49 (1), p.113
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Showing 1 to 20 of 25 results

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α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

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Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

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The mitochondrial permeability transition phenomenon elucidated by cryo-EM reveals the genuine impact of calcium overload on mitochondrial structure and function

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Tamoxifen-induced knockdown of the mitochondrial calcium uniporter in Thy1-expressing neurons protects mice from hypoxic/ischemic brain injury

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C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition

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Refractive Index Imaging Reveals That Elimination of the ATP Synthase C Subunit Does Not Prevent the Adenine Nucleotide Translocase-Dependent Mitochondrial Permeability Transition

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Mitochondrial Cyclosporine A-Independent Palmitate/Ca2+-Induced Permeability Transition Pore (PA-mPT Pore) and Its Role in Mitochondrial Function and Protection against Calcium Overload and Glutamate...

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From ATP synthase dimers to C-ring conformational changes: unified model of the mitochondrial permeability transition pore

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Polyhydroxybutyrate Targets Mammalian Mitochondria and Increases Permeability of Plasmalemmal and Mitochondrial Membranes

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Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels

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Formation of High-Conductive C Subunit Channels upon Interaction with Cyclophilin D

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Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity

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Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex

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Mitochondrial Ca2+ uptake pathways

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Correction: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

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Correction: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

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MAC inhibitors antagonize the pro-apoptotic effects of tBid and disassemble Bax / Bak oligomers

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Mitochondrial Cyclosporine A-Independent Palmitate/Ca 2+ -Induced Permeability Transition Pore (PA-mPT Pore) and Its Role in Mitochondrial Function and Protection against Calcium Overload and Glutamat...

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C subunit of the ATP synthase is an amyloidogenic channel-forming peptide: possible implications in mitochondrial pathogenesis

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Mitochondrial Ca^sup 2+^ uptake pathways

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