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Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules
Author / Creator:Stravalaci, Matteo ; Pagani, Isabel ; Paraboschi, Elvezia Maria ; Pedotti, Mattia ; Doni, Andrea ; Scavello, Francesco ; Mapelli, Sarah N. ; Sironi, Marina ; Perucchini, Chiara ; Varani, Luca ; Matkovic, Milos ; Cavalli, Andrea ; Cesana, Daniela ; Gallina, Pierangela ; Pedemonte, Nicoletta ; Capurro, Valeria ; Clementi, Nicola ; Mancini, Nicasio ; Invernizzi, Pietro ; Bayarri-Olmos, Rafael ; Garred, Peter ; Rappuoli, Rino ; Duga, Stefano ; Bottazzi, Barbara ; Uguccioni, Mariagrazia ; Asselta, Rosanna ; Vicenzi, Elisa ; Mantovani, Alberto ; Garlanda, Cecilia
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2022-02, Vol.23 (2), p.275-286
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Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment
Author / Creator:Capurro, Valeria ; Tomati, Valeria ; Sondo, Elvira ; Renda, Mario ; Borrelli, Anna ; Pastorino, Cristina ; Guidone, Daniela ; Venturini, Arianna ; Giraudo, Alessandro ; Mandrup Bertozzi, Sine ; Musante, Ilaria ; Bertozzi, Fabio ; Bandiera, Tiziano ; Zara, Federico ; Galietta, Luis J. V. ; Pedemonte, Nicoletta
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2021-05, Vol.22 (10), p.5262
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Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis
Author / Creator:Haque, A. K. M. Ashiqul ; Dewerth, Alexander ; Antony, Justin S. ; Riethmüller, Joachim ; Schweizer, Georg R. ; Weinmann, Petra ; Latifi, Ngadhnjim ; Yasar, Hanzey ; Pedemonte, Nicoletta ; Sondo, Elvira ; Weidensee, Brian ; Ralhan, Anjali ; Laval, Julie ; Schlegel, Patrick ; Seitz, Christian ; Loretz, Brigitta ; Lehr, Claus-Michael ; Handgretinger, Rupert ; Kormann, Michael S. D.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-11, Vol.8 (1), p.16776-14, Article 16776
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A Novel LC-MS/MS Method for the Measurement of Elexacaftor, Tezacaftor and Ivacaftor in Plasma, Dried Plasma Spot (DPS) and Whole Blood in Volumetric Absorptive Microsampling (VAMS) Devices
Author / Creator:Pigliasco, Federica ; Cafaro, Alessia ; Barco, Sebastiano ; Cresta, Federico ; Casciaro, Rosaria ; Pedemonte, Nicoletta ; Mattioli, Francesca ; Castellani, Carlo ; Cangemi, Giuliana
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2025-02, Vol.17 (2), p.200
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Probing Allosteric Hsp70 Inhibitors by Molecular Modelling Studies to Expedite the Development of Novel Combined F508del CFTR Modulators
Author / Creator:Sabbadini, Roberto ; Pesce, Emanuela ; Parodi, Alice ; Mustorgi, Eleonora ; Bruzzone, Santina ; Pedemonte, Nicoletta ; Casale, Monica ; Millo, Enrico ; Cichero, Elena
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-12, Vol.14 (12), p.1296
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New Insights into the Binding Features of F508del CFTR Potentiators: A Molecular Docking, Pharmacophore Mapping and QSAR Analysis Approach
Author / Creator:Righetti, Giada ; Casale, Monica ; Tonelli, Michele ; Liessi, Nara ; Fossa, Paola ; Pedemonte, Nicoletta ; Millo, Enrico ; Cichero, Elena
Publisher:Switzerland: MDPI
Journal title:Pharmaceuticals (Basel, Switzerland), 2020-12, Vol.13 (12), p.445
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Simultaneous Quantification of Ivacaftor, Tezacaftor, and Elexacaftor in Cystic Fibrosis Patients’ Plasma by a Novel LC–MS/MS Method
Author / Creator:Pigliasco, Federica ; Cafaro, Alessia ; Stella, Manuela ; Baiardi, Giammarco ; Barco, Sebastiano ; Pedemonte, Nicoletta ; D’Orsi, Claudia ; Cresta, Federico ; Casciaro, Rosaria ; Castellani, Carlo ; Calevo, Maria Grazia ; Mattioli, Francesca ; Cangemi, Giuliana
Publisher:Switzerland: MDPI AG
Journal title:Biomedicines, 2023-02, Vol.11 (2), p.628
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Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation
Author / Creator:Tomati, Valeria ; Sondo, Elvira ; Armirotti, Andrea ; Caci, Emanuela ; Pesce, Emanuela ; Marini, Monica ; Gianotti, Ambra ; Ju Jeon, Young ; Cilli, Michele ; Pistorio, Angela ; Mastracci, Luca ; Ravazzolo, Roberto ; Scholte, Bob ; Ronai, Ze’ev ; Galietta, Luis J. V. ; Pedemonte, Nicoletta
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-07, Vol.5 (1), p.12138, Article 12138
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Journey on VX-809-Based Hybrid Derivatives towards Drug-like F508del-CFTR Correctors: From Molecular Modeling to Chemical Synthesis and Biological Assays
Author / Creator:Parodi, Alice ; Righetti, Giada ; Pesce, Emanuela ; Salis, Annalisa ; Tomati, Valeria ; Pastorino, Cristina ; Tasso, Bruno ; Benvenuti, Mirko ; Damonte, Gianluca ; Pedemonte, Nicoletta ; Cichero, Elena ; Millo, Enrico
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2022-02, Vol.15 (3), p.274
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Interplay between ALK2R206H mutant receptor and autophagy signaling regulates receptor stability and its chondrogenic functions
Author / Creator:Coculo, Laura ; Wits, Marius ; Mariani, Irene ; Fianco, Giulia ; Cappato, Serena ; Bocciardi, Renata ; Pedemonte, Nicoletta ; Volpe, Elisabetta ; Ciolfi, Serena ; Sessa, Rosario Luigi ; Rinaldo, Serena ; Cutruzzolà, Francesca ; Trisciuoglio, Daniela ; Goumans, Marie-Josè ; Sanchez-Duffhues, Gonzalo ; Stagni, Venturina
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2025-03, Vol.11 (1), p.117-13, Article 117
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CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium
Author / Creator:Braccia, Clarissa ; Christopher, Josie A. ; Crook, Oliver M. ; Breckels, Lisa M. ; Queiroz, Rayner M. L. ; Liessi, Nara ; Tomati, Valeria ; Capurro, Valeria ; Bandiera, Tiziano ; Baldassari, Simona ; Pedemonte, Nicoletta ; Lilley, Kathryn S. ; Armirotti, Andrea
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-06, Vol.11 (12), p.1938
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Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening
Author / Creator:Kalid, Ori ; Mense, Martin ; Fischman, Sharon ; Shitrit, Alina ; Bihler, Hermann ; Ben-Zeev, Efrat ; Schutz, Nili ; Pedemonte, Nicoletta ; Thomas, Philip J. ; Bridges, Robert J. ; Wetmore, Diana R. ; Marantz, Yael ; Senderowitz, Hanoch
Publisher:Dordrecht: Springer Netherlands
Journal title:Journal of computer-aided molecular design, 2010-12, Vol.24 (12), p.971-991
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Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice
Author / Creator:Maurya, Devendra Kumar ; Henriques, Tiago ; Marini, Monica ; Pedemonte, Nicoletta ; Galietta, Luis J. V. ; Rock, Jason R. ; Harfe, Brian D. ; Menini, Anna
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015, Vol.10 (6), p.e0129171-e0129171
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In Type 1 Diabetes a Subset of Anti-Coxsackievirus B4 Antibodies Recognize Autoantigens and Induce Apoptosis of Pancreatic Beta Cells
Author / Creator:Bason, Caterina ; Lorini, Renata ; Lunardi, Claudio ; Dolcino, Marzia ; Giannattasio, Alessandro ; d’Annunzio, Giuseppe ; Rigo, Antonella ; Pedemonte, Nicoletta ; Corrocher, Roberto ; Puccetti, Antonio
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-02, Vol.8 (2), p.e57729-e57729
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Gain- and Loss-of-Function CFTR Alleles Are Associated with COVID-19 Clinical Outcomes
Author / Creator:Baldassarri, Margherita ; Zguro, Kristina ; Tomati, Valeria ; Pastorino, Cristina ; Fava, Francesca ; Croci, Susanna ; Bruttini, Mirella ; Picchiotti, Nicola ; Furini, Simone ; Pedemonte, Nicoletta ; Gabbi, Chiara ; Renieri, Alessandra ; Fallerini, Chiara
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-12, Vol.11 (24), p.4096
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Editorial: Special Issue on “Therapeutic Approaches for Cystic Fibrosis”
Author / Creator:Pedemonte, Nicoletta
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-09, Vol.21 (18), p.6657
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Gelsolin Secretion in Interleukin-4-treated Bronchial Epithelia and in Asthmatic Airways
Author / Creator:Candiano, Giovanni ; Bruschi, Maurizio ; Pedemonte, Nicoletta ; Caci, Emanuela ; Liberatori, Sabrina ; Bini, Luca ; Pellegrini, Carlo ; Vigano, Mario ; O'Connor, Brian J ; Lee, Tak H ; Galietta, Luis J. V ; Zegarra-Moran, Olga
Publisher:New York, NY: Am Thoracic Soc
Journal title:American journal of respiratory and critical care medicine, 2005-11, Vol.172 (9), p.1090-1096
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Proteomics and Metabolomics for Cystic Fibrosis Research
Author / Creator:Liessi, Nara ; Pedemonte, Nicoletta ; Armirotti, Andrea ; Braccia, Clarissa
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-07, Vol.21 (15), p.5439
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Targeting the E1 ubiquitin-activating enzyme (UBA1) improves elexacaftor/tezacaftor/ivacaftor efficacy towards F508del and rare misfolded CFTR mutants
Author / Creator:Borgo, Christian ; D’Amore, Claudio ; Capurro, Valeria ; Tomati, Valeria ; Sondo, Elvira ; Cresta, Federico ; Castellani, Carlo ; Pedemonte, Nicoletta ; Salvi, Mauro
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2022-04, Vol.79 (4), p.192-192, Article 192
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Comprehensive Analysis of Combinatorial Pharmacological Treatments to Correct Nonsense Mutations in the CFTR Gene
Author / Creator:Venturini, Arianna ; Borrelli, Anna ; Musante, Ilaria ; Scudieri, Paolo ; Capurro, Valeria ; Renda, Mario ; Pedemonte, Nicoletta ; Galietta, Luis J. V.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-11, Vol.22 (21), p.11972
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Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules

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Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment

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Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis

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A Novel LC-MS/MS Method for the Measurement of Elexacaftor, Tezacaftor and Ivacaftor in Plasma, Dried Plasma Spot (DPS) and Whole Blood in Volumetric Absorptive Microsampling (VAMS) Devices

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Probing Allosteric Hsp70 Inhibitors by Molecular Modelling Studies to Expedite the Development of Novel Combined F508del CFTR Modulators

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New Insights into the Binding Features of F508del CFTR Potentiators: A Molecular Docking, Pharmacophore Mapping and QSAR Analysis Approach

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Simultaneous Quantification of Ivacaftor, Tezacaftor, and Elexacaftor in Cystic Fibrosis Patients’ Plasma by a Novel LC–MS/MS Method

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Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation

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Journey on VX-809-Based Hybrid Derivatives towards Drug-like F508del-CFTR Correctors: From Molecular Modeling to Chemical Synthesis and Biological Assays

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Interplay between ALK2R206H mutant receptor and autophagy signaling regulates receptor stability and its chondrogenic functions

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CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium

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Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening

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Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice

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In Type 1 Diabetes a Subset of Anti-Coxsackievirus B4 Antibodies Recognize Autoantigens and Induce Apoptosis of Pancreatic Beta Cells

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Gain- and Loss-of-Function CFTR Alleles Are Associated with COVID-19 Clinical Outcomes

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Editorial: Special Issue on “Therapeutic Approaches for Cystic Fibrosis”

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Gelsolin Secretion in Interleukin-4-treated Bronchial Epithelia and in Asthmatic Airways

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Proteomics and Metabolomics for Cystic Fibrosis Research

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Targeting the E1 ubiquitin-activating enzyme (UBA1) improves elexacaftor/tezacaftor/ivacaftor efficacy towards F508del and rare misfolded CFTR mutants

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Comprehensive Analysis of Combinatorial Pharmacological Treatments to Correct Nonsense Mutations in the CFTR Gene

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