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63 results for Plasmodium+-+enzymology

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Targeting Plasmodium PI(4)K to eliminate malaria
Author / Creator:McNamara, Case W. ; Lee, Marcus C. S. ; Lim, Chek Shik ; Lim, Siau Hoi ; Roland, Jason ; Nagle, Advait ; Simon, Oliver ; Yeung, Bryan K. S. ; Chatterjee, Arnab K. ; McCormack, Susan L. ; Manary, Micah J. ; Zeeman, Anne-Marie ; Dechering, Koen J. ; Kumar, T. R. Santha ; Henrich, Philipp P. ; Gagaring, Kerstin ; Ibanez, Maureen ; Kato, Nobutaka ; Kuhen, Kelli L. ; Fischli, Christoph ; Rottmann, Matthias ; Plouffe, David M. ; Bursulaya, Badry ; Meister, Stephan ; Rameh, Lucia ; Trappe, Joerg ; Haasen, Dorothea ; Timmerman, Martijn ; Sauerwein, Robert W. ; Suwanarusk, Rossarin ; Russell, Bruce ; Renia, Laurent ; Nosten, Francois ; Tully, David C. ; Kocken, Clemens H. M. ; Glynne, Richard J. ; Bodenreider, Christophe ; Fidock, David A. ; Diagana, Thierry T. ; Winzeler, Elizabeth A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-12, Vol.504 (7479), p.248-253
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Structure- and function-based design of Plasmodium-selective proteasome inhibitors
Author / Creator:Li, Hao ; O’Donoghue, Anthony J. ; van der Linden, Wouter A. ; Xie, Stanley C. ; Yoo, Euna ; Foe, Ian T. ; Tilley, Leann ; Craik, Charles S. ; da Fonseca, Paula C. A. ; Bogyo, Matthew
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-02, Vol.530 (7589), p.233-236
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Structural comparison of human and Plasmodium proteasome β5 subunits: informing selective inhibitor design for anti-malaria agents
Author / Creator:Yasir, Muhammad ; Park, Jinyoung ; Han, Eun-Taek ; Park, Won Sun ; Han, Jin-Hee ; Chun, Wanjoo
Publisher:England: BioMed Central
Journal title:Malaria journal, 2025-01, Vol.24 (1), p.21-12, Article 21
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Structural basis for discriminatory recognition of Plasmodium lactate dehydrogenase by a DNA aptamer
Author / Creator:Cheung, Yee-Wai ; Kwok, Jane ; Law, Alan W. L. ; Watt, Rory M. ; Kotaka, Masayo ; Tanner, Julian A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (40), p.15967-15972
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Plasmodial Kinase Inhibitors Targeting Malaria: Recent Developments
Author / Creator:Mustière, Romain ; Vanelle, Patrice ; Primas, Nicolas
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-12, Vol.25 (24), p.5949
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Regulation of Sexual Development of Plasmodium by Translational Repression
Author / Creator:Mair, Gunnar R ; Braks, Joanna A.M ; Garver, Lindsey S ; Wiegant, Joop C.A.G ; Hall, Neil ; Dirks, Roeland W ; Khan, Shahid M ; Dimopoulos, George ; Janse, Chris J ; Waters, Andrew P
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2006-08, Vol.313 (5787), p.667-669
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An Update on Development of Small-Molecule Plasmodial Kinase Inhibitors
Author / Creator:Moolman, Chantalle ; Sluis, Rencia van der ; Beteck, Richard M ; Legoabe, Lesetja J
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-11, Vol.25 (21), p.5182
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Plasmodium dihydrofolate reductase is a second enzyme target for the antimalarial action of triclosan
Author / Creator:Bilsland, Elizabeth ; van Vliet, Liisa ; Williams, Kevin ; Feltham, Jack ; Carrasco, Marta P. ; Fotoran, Wesley L. ; Cubillos, Eliana F. G. ; Wunderlich, Gerhard ; Grøtli, Morten ; Hollfelder, Florian ; Jackson, Victoria ; King, Ross D. ; Oliver, Stephen G.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-01, Vol.8 (1), p.1038-8, Article 1038
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An evolutionary perspective on the kinome of malaria parasites
Author / Creator:Talevich, Eric ; Tobin, Andrew B. ; Kannan, Natarajan ; Doerig, Christian
Publisher:England: The Royal Society
Journal title:Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2012-09, Vol.367 (1602), p.2607-2618
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QSAR Study of N -Myristoyltransferase Inhibitors of Antimalarial Agents
Author / Creator:Santos-Garcia, Letícia ; de Mecenas Filho, Marco Antônio ; Musilek, Kamil ; Kuca, Kamil ; Ramalho, Teodorico Castro ; da Cunha, Elaine Fontes Ferreira
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-09, Vol.23 (9), p.2348
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Insights into antifolate resistance from malarial DHFR-TS structures
Author / Creator:Yuvaniyama, Jirundon ; Chitnumsub, Penchit ; Kamchonwongpaisan, Sumalee ; Vanichtanankul, Jarunee ; Sirawaraporn, Worachart ; Taylor, Paul ; Walkinshaw, Malcolm D. ; Yuthavong, Yongyuth
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2003-05, Vol.10 (5), p.357-365
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Antimalarials: Novel proteasome inhibitor combats malaria
Author / Creator:Crunkhorn, Sarah
Publisher:England: Nature Publishing Group
Journal title:Nature reviews. Drug discovery, 2016-04, Vol.15 (4), p.232-233
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Plasmodium pseudo-Tyrosine Kinase-like binds PP1 and SERA5 and is exported to host erythrocytes
Author / Creator:Gnangnon, Bénédicte ; Fréville, Aline ; Cailliau, Katia ; Leroy, Catherine ; De Witte, Caroline ; Tulasne, David ; Martoriarti, Alain ; Jung, Vincent ; Guerrera, Ida Chiara ; Marion, Sabrina ; Khalife, Jamal ; Pierrot, Christine
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-05, Vol.9 (1), p.8120, Article 8120
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A non-canonical sensing pathway mediates Plasmodium adaptation to amino acid deficiency
Author / Creator:Marreiros, Inês M. ; Marques, Sofia ; Parreira, Ana ; Mastrodomenico, Vincent ; Mounce, Bryan C. ; Harris, Chantal T. ; Kafsack, Björn F. ; Billker, Oliver ; Zuzarte-Luís, Vanessa ; Mota, Maria M.
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2023-02, Vol.6 (1), p.205-205, Article 205
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Malaria: A step closer to elimination?
Author / Creator:Flemming, Alexandra
Publisher:England: Nature Publishing Group
Journal title:Nature reviews. Drug discovery, 2014-01, Vol.13 (1), p.20-20
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Diagnostic Performance of Rapid Diagnostic Tests versus Blood Smears for Malaria in US Clinical Practice
Author / Creator:Stauffer, William M. ; Cartwright, Charles P. ; Olson, Douglas A. ; Juni, Billie Anne ; Taylor, Charlotte M. ; Bowers, Susan H. ; Hanson, Kevan L. ; Rosenblatt, Jon E. ; Boulware, David R.
Publisher:Oxford: The University of Chicago Press
Journal title:Clinical infectious diseases, 2009-09, Vol.49 (6), p.908-913
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Genetic Characterization of Plasmodium Putative Pantothenate Kinase Genes Reveals Their Essential Role in Malaria Parasite Transmission to the Mosquito
Author / Creator:Hart, Robert J. ; Cornillot, Emmanuel ; Abraham, Amanah ; Molina, Emily ; Nation, Catherine S. ; Ben Mamoun, Choukri ; Aly, Ahmed S. I.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-09, Vol.6 (1), p.33518-33518, Article 33518
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Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity
Author / Creator:No, Joo Hwan ; de Macedo Dossin, Fernando ; Zhang, Yonghui ; Liu, Yi-Liang ; Zhu, Wei ; Feng, Xinxin ; Yoo, Jinyoung Anny ; Lee, Eunhae ; Wang, Ke ; Hui, Raymond ; Freitas-Junior, Lucio H ; Oldfield, Eric
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (11), p.4058-4063
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Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasites
Author / Creator:Ponsuwanna, Patrath ; Kochakarn, Theerarat ; Bunditvorapoom, Duangkamon ; Kümpornsin, Krittikorn ; Otto, Thomas D ; Ridenour, Chase ; Chotivanich, Kesinee ; Wilairat, Prapon ; White, Nicholas J ; Miotto, Olivo ; Chookajorn, Thanat
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2016-01, Vol.15 (1), p.51-51, Article 51
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Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host
Author / Creator:Koussis, Konstantinos ; Goulielmaki, Evi ; Chalari, Anna ; Withers-Martinez, Chrislaine ; Siden-Kiamos, Inga ; Matuschewski, Kai ; Loukeris, Thanasis G
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-01, Vol.12 (1), p.e0170260-e0170260
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Targeting Plasmodium PI(4)K to eliminate malaria

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Structure- and function-based design of Plasmodium-selective proteasome inhibitors

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Structural comparison of human and Plasmodium proteasome β5 subunits: informing selective inhibitor design for anti-malaria agents

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Structural basis for discriminatory recognition of Plasmodium lactate dehydrogenase by a DNA aptamer

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Plasmodial Kinase Inhibitors Targeting Malaria: Recent Developments

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Regulation of Sexual Development of Plasmodium by Translational Repression

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An Update on Development of Small-Molecule Plasmodial Kinase Inhibitors

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Plasmodium dihydrofolate reductase is a second enzyme target for the antimalarial action of triclosan

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An evolutionary perspective on the kinome of malaria parasites

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QSAR Study of N -Myristoyltransferase Inhibitors of Antimalarial Agents

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Insights into antifolate resistance from malarial DHFR-TS structures

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Antimalarials: Novel proteasome inhibitor combats malaria

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Plasmodium pseudo-Tyrosine Kinase-like binds PP1 and SERA5 and is exported to host erythrocytes

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A non-canonical sensing pathway mediates Plasmodium adaptation to amino acid deficiency

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Malaria: A step closer to elimination?

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Diagnostic Performance of Rapid Diagnostic Tests versus Blood Smears for Malaria in US Clinical Practice

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Genetic Characterization of Plasmodium Putative Pantothenate Kinase Genes Reveals Their Essential Role in Malaria Parasite Transmission to the Mosquito

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Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity

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Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasites

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Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host

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