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52 results for Polyubiquitin+-+chemistry

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ArticlesPeer ReviewedFull Text
Insights into ubiquitin chain architecture using Ub-clipping
Author / Creator:Swatek, Kirby N. ; Usher, Joanne L. ; Kueck, Anja F. ; Gladkova, Christina ; Mevissen, Tycho E. T. ; Pruneda, Jonathan N. ; Skern, Tim ; Komander, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-08, Vol.572 (7770), p.533-537
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Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages
Author / Creator:Kulathu, Yogesh ; Komander, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2012-08, Vol.13 (8), p.508-523
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The ubiquitin ligase parkin mediates resistance to intracellular pathogens
Author / Creator:Manzanillo, Paolo S. ; Ayres, Janelle S. ; Watson, Robert O. ; Collins, Angela C. ; Souza, Gianne ; Rae, Chris S. ; Schneider, David S. ; Nakamura, Ken ; Shiloh, Michael U. ; Cox, Jeffery S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-09, Vol.501 (7468), p.512-516
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Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors
Author / Creator:Richards, Mark W. ; Burgess, Selena G. ; Poon, Evon ; Carstensen, Anne ; Eilers, Martin ; Chesler, Louis ; Bayliss, Richard
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (48), p.13726-13731
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Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
Author / Creator:Wertz, Ingrid E. ; Newton, Kim ; Seshasayee, Dhaya ; Kusam, Saritha ; Lam, Cynthia ; Zhang, Juan ; Popovych, Nataliya ; Helgason, Elizabeth ; Schoeffler, Allyn ; Jeet, Surinder ; Ramamoorthi, Nandhini ; Kategaya, Lorna ; Newman, Robert J. ; Horikawa, Keisuke ; Dugger, Debra ; Sandoval, Wendy ; Mukund, Susmith ; Zindal, Anuradha ; Martin, Flavius ; Quan, Clifford ; Tom, Jeffrey ; Fairbrother, Wayne J. ; Townsend, Michael ; Warming, Søren ; DeVoss, Jason ; Liu, Jinfeng ; Dueber, Erin ; Caplazi, Patrick ; Lee, Wyne P. ; Goodnow, Christopher C. ; Balazs, Mercedesz ; Yu, Kebing ; Kolumam, Ganesh ; Dixit, Vishva M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-12, Vol.528 (7582), p.370-375
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Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series
Author / Creator:Ikeda, Fumiyo ; Dikic, Ivan
Publisher:England: Springer Nature B.V
Journal title:EMBO reports, 2008-06, Vol.9 (6), p.536-542
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LUBAC synthesizes linear ubiquitin chains via a thioester intermediate
Author / Creator:Stieglitz, Benjamin ; Morris-Davies, Aylin C ; Koliopoulos, Marios G ; Christodoulou, Evangelos ; Rittinger, Katrin
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:EMBO reports, 2012-09, Vol.13 (9), p.840-846
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Synthetic polyubiquitinated α-Synuclein reveals important insights into the roles of the ubiquitin chain in regulating its pathophysiology
Author / Creator:Haj-Yahya, Mahmood ; Fauvet, Bruno ; Herman-Bachinsky, Yifat ; Hejjaoui, Mirva ; Bavikar, Sudhir N. ; Karthikeyan, Subramanian Vedhanarayanan ; Ciechanover, Aaron ; Lashuel, Hilal A. ; Brik, Ashraf
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.17726-17731
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Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X
Author / Creator:Paudel, Prajwal ; Zhang, Qi ; Leung, Charles ; Greenberg, Harrison C. ; Guo, Yusong ; Chern, Yi-Hsuan ; Dong, Aiping ; Li, Yanjun ; Vedadi, Masoud ; Zhuang, Zhihao ; Tong, Yufeng
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (15), p.7288-7297
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Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
Author / Creator:Komander, David ; Reyes-Turcu, Francisca ; Licchesi, Julien D F ; Odenwaelder, Peter ; Wilkinson, Keith D ; Barford, David
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:EMBO reports, 2009-05, Vol.10 (5), p.466-473
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Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler
Author / Creator:Liwocha, Joanna ; Krist, David T. ; van der Heden van Noort, Gerbrand J. ; Hansen, Fynn M. ; Truong, Vinh H. ; Karayel, Ozge ; Purser, Nicholas ; Houston, Daniel ; Burton, Nicole ; Bostock, Mark J. ; Sattler, Michael ; Mann, Matthias ; Harrison, Joseph S. ; Kleiger, Gary ; Ovaa, Huib ; Schulman, Brenda A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2021-03, Vol.17 (3), p.272-279
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The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates
Author / Creator:Morimoto, Daichi ; Walinda, Erik ; Fukada, Harumi ; Sou, Yu-Shin ; Kageyama, Shun ; Hoshino, Masaru ; Fujii, Takashi ; Tsuchiya, Hikaru ; Saeki, Yasushi ; Arita, Kyohei ; Ariyoshi, Mariko ; Tochio, Hidehito ; Iwai, Kazuhiro ; Namba, Keiichi ; Komatsu, Masaaki ; Tanaka, Keiji ; Shirakawa, Masahiro
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-01, Vol.6 (1), p.6116-6116, Article 6116
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ArticlesPeer ReviewedFull Text
Ub-ProT reveals global length and composition of protein ubiquitylation in cells
Author / Creator:Tsuchiya, Hikaru ; Burana, Daocharad ; Ohtake, Fumiaki ; Arai, Naoko ; Kaiho, Ai ; Komada, Masayuki ; Tanaka, Keiji ; Saeki, Yasushi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-02, Vol.9 (1), p.524-10, Article 524
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ArticlesPeer ReviewedFull Text
Polyubiquitin chains: functions, structures, and mechanisms
Author / Creator:Li, W ; Ye, Y
Publisher:Basel: Basel : SP Birkhäuser Verlag Basel
Journal title:Cellular and molecular life sciences : CMLS, 2008-08, Vol.65 (15), p.2397-2406
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Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site
Author / Creator:Watson, Edmond R. ; Grace, Christy R. R. ; Zhang, Wei ; Miller, Darcie J. ; Davidson, Iain F. ; Prabu, J. Rajan ; Yu, Shanshan ; Bolhuis, Derek L. ; Kulko, Elizaveta T. ; Vollrath, Ronnald ; Haselbach, David ; Stark, Holger ; Peters, Jan-Michael ; Brown, Nicholas G. ; Sidhu, Sachdev S. ; Schulman, Brenda A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (35), p.17280-17289
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Defining the geometry of the two-component proteasome degron
Author / Creator:Inobe, Tomonao ; Fishbain, Susan ; Prakash, Sumit ; Matouschek, Andreas
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2011-03, Vol.7 (3), p.161-167
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Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains
Author / Creator:Sato, Yusuke ; Yoshikawa, Azusa ; Yamagata, Atsushi ; Mimura, Hisatoshi ; Yamashita, Masami ; Ookata, Kayoko ; Nureki, Osamu ; Iwai, Kazuhiro ; Komada, Masayuki ; Fukai, Shuya
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2008-09, Vol.455 (7211), p.358-362
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Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome
Author / Creator:Saeki, Yasushi ; Kudo, Tai ; Sone, Takayuki ; Kikuchi, Yoshiko ; Yokosawa, Hideyoshi ; Toh-e, Akio ; Tanaka, Keiji
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2009-02, Vol.28 (4), p.359-371
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VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo
Author / Creator:Ren, Xuefeng ; Hurley, James H
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2010-03, Vol.29 (6), p.1045-1054
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Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80
Author / Creator:Sato, Yusuke ; Yoshikawa, Azusa ; Mimura, Hisatoshi ; Yamashita, Masami ; Yamagata, Atsushi ; Fukai, Shuya
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2009-08, Vol.28 (16), p.2461-2468
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Showing 1 to 20 of 52 results

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Insights into ubiquitin chain architecture using Ub-clipping

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Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

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The ubiquitin ligase parkin mediates resistance to intracellular pathogens

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Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors

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Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

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Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series

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LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

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Synthetic polyubiquitinated α-Synuclein reveals important insights into the roles of the ubiquitin chain in regulating its pathophysiology

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Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X

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Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

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Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

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The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates

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Ub-ProT reveals global length and composition of protein ubiquitylation in cells

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Polyubiquitin chains: functions, structures, and mechanisms

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Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site

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Defining the geometry of the two-component proteasome degron

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Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

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Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

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VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo

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Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80

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