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ArticlesPeer ReviewedFull Text
Silymarin prevents acetaminophen-induced hepatotoxicity in mice
Author / Creator:Papackova, Zuzana ; Heczkova, Marie ; Dankova, Helena ; Sticova, Eva ; Lodererova, Alena ; Bartonova, Lenka ; Poruba, Martin ; Cahova, Monika
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-01, Vol.13 (1), p.e0191353
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ArticlesPeer ReviewedFull Text
Beneficial effects of troxerutin on metabolic disorders in non-obese model of metabolic syndrome
Author / Creator:Malinska, Hana ; Hüttl, Martina ; Oliyarnyk, Olena ; Markova, Irena ; Poruba, Martin ; Racova, Zuzana ; Kazdova, Ludmila ; Vecera, Rostislav
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-08, Vol.14 (8), p.e0220377-e0220377
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ArticlesPeer ReviewedFull Text
Ovariectomy-Induced Hepatic Lipid and Cytochrome P450 Dysmetabolism Precedes Serum Dyslipidemia
Author / Creator:Malinská, Hana ; Hüttl, Martina ; Miklánková, Denisa ; Trnovská, Jaroslava ; Zapletalová, Iveta ; Poruba, Martin ; Marková, Irena
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-04, Vol.22 (9), p.4527
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ArticlesPeer ReviewedFull Text
The Beneficial Additive Effect of Silymarin in Metformin Therapy of Liver Steatosis in a Pre-Diabetic Model
Author / Creator:Hüttl, Martina ; Markova, Irena ; Miklankova, Denisa ; Zapletalova, Iveta ; Poruba, Martin ; Racova, Zuzana ; Vecera, Rostislav ; Malinska, Hana
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2021-12, Vol.14 (1), p.45
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ArticlesPeer ReviewedFull Text
Beneficial Effect of Fenofibrate and Silymarin on Hepatic Steatosis and Gene Expression of Lipogenic and Cytochrome P450 Enzymes in Non-Obese Hereditary Hypertriglyceridemic Rats
Author / Creator:Vecera, Rostislav ; Poruba, Martin ; Hüttl, Martina ; Malinska, Hana ; Oliyarnyk, Olena ; Markova, Irena ; Racova, Zuzana ; Soukop, Jan ; Kazdova, Ludmila
Publisher:Switzerland: MDPI
Journal title:Current issues in molecular biology, 2022-04, Vol.44 (5), p.1889-1900
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ArticlesPeer ReviewedFull Text
Beneficial Effect of Fenofibrate in Combination with Silymarin on Parameters of Hereditary Hypertriglyceridemia-Induced Disorders in an Animal Model of Metabolic Syndrome
Author / Creator:Soukop, Jan ; Kazdová, Ludmila ; Hüttl, Martina ; Malínská, Hana ; Marková, Irena ; Oliyarnyk, Olena ; Miklánková, Denisa ; Gurská, Soňa ; Rácová, Zuzana ; Poruba, Martin ; Večeřa, Rostislav
Publisher:Switzerland: MDPI AG
Journal title:Biomedicines, 2025-01, Vol.13 (1), p.212
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ArticlesPeer ReviewedFull Text
In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia
Author / Creator:Hüttl, Martina ; Markova, Irena ; Miklankova, Denisa ; Zapletalova, Iveta ; Poruba, Martin ; Haluzik, Martin ; Vaněčkova, Ivana ; Malinska, Hana
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-10, Vol.22 (21), p.11513
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ArticlesPeer ReviewedFull Text
Metformin Affects Cardiac Arachidonic Acid Metabolism and Cardiac Lipid Metabolite Storage in a Prediabetic Rat Model
Author / Creator:Miklankova, Denisa ; Markova, Irena ; Hüttl, Martina ; Zapletalova, Iveta ; Poruba, Martin ; Malinska, Hana
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2021-07, Vol.22 (14), p.7680
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ArticlesPeer ReviewedFull Text
The Combination of Atorvastatin With Silymarin Enhances Hypolipidemic, Antioxidant and Anti-Inflammatory Effects in a Rat Model of Metabolic Syndrome
Author / Creator:MARKOVÁ, I ; MALÍNSKÁ, H ; HÜTTL, M ; MIKLÁNKOVÁ, D ; OLIYARNYK, O ; PORUBA, M ; RÁCOVÁ, Z ; KAZDOVÁ, L ; VEČEŘA, R
Publisher:Praha: Institute of Physiology
Journal title:Physiological research, 2021-02, Vol.70 (1), p.33-43
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ArticlesPeer ReviewedFull Text
in vitro and in silico studies of interaction of synthetic 2,6,9-trisubstituted purine kinase inhibitors BPA-302, BP-21 and BP-117 with liver drug-metabolizing cytochromes P450
Author / Creator:Špičáková, A ; Kraus, P ; Gucký, T ; Kryštof, V ; Strnad, M ; Bazgier, V ; Otyepka, M ; Kubíčková, V ; Poruba, M ; Rácová, Z ; Zapletalová, I ; Anzenbacher, P
Publisher:Praha: Institute of Physiology
Journal title:Physiological research, 2020-12, Vol.69 (Suppl 4), p.S627-S636
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Silymarin prevents acetaminophen-induced hepatotoxicity in mice

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Beneficial effects of troxerutin on metabolic disorders in non-obese model of metabolic syndrome

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Ovariectomy-Induced Hepatic Lipid and Cytochrome P450 Dysmetabolism Precedes Serum Dyslipidemia

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The Beneficial Additive Effect of Silymarin in Metformin Therapy of Liver Steatosis in a Pre-Diabetic Model

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Beneficial Effect of Fenofibrate and Silymarin on Hepatic Steatosis and Gene Expression of Lipogenic and Cytochrome P450 Enzymes in Non-Obese Hereditary Hypertriglyceridemic Rats

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Beneficial Effect of Fenofibrate in Combination with Silymarin on Parameters of Hereditary Hypertriglyceridemia-Induced Disorders in an Animal Model of Metabolic Syndrome

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In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia

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Metformin Affects Cardiac Arachidonic Acid Metabolism and Cardiac Lipid Metabolite Storage in a Prediabetic Rat Model

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The Combination of Atorvastatin With Silymarin Enhances Hypolipidemic, Antioxidant and Anti-Inflammatory Effects in a Rat Model of Metabolic Syndrome

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in vitro and in silico studies of interaction of synthetic 2,6,9-trisubstituted purine kinase inhibitors BPA-302, BP-21 and BP-117 with liver drug-metabolizing cytochromes P450

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