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SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
Author / Creator:Mazur, Pawel K. ; Reynoird, Nicolas ; Khatri, Purvesh ; Jansen, Pascal W. T. C. ; Wilkinson, Alex W. ; Liu, Shichong ; Barbash, Olena ; Van Aller, Glenn S. ; Huddleston, Michael ; Dhanak, Dashyant ; Tummino, Peter J. ; Kruger, Ryan G. ; Garcia, Benjamin A. ; Butte, Atul J. ; Vermeulen, Michiel ; Sage, Julien ; Gozani, Or
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-06, Vol.510 (7504), p.283-287
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The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity
Author / Creator:Collison, Adam ; Hatchwell, Luke ; Verrills, Nicole ; Wark, Peter A B ; de Siqueira, Ana Pereira ; Tooze, Melinda ; Carpenter, Helen ; Don, Anthony S ; Morris, Jonathan C ; Zimmermann, Nives ; Bartlett, Nathan W ; Rothenberg, Marc E ; Johnston, Sebastian L ; Foster, Paul S ; Mattes, Joerg
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2013-02, Vol.19 (2), p.232-237
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ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A
Author / Creator:Oleinik, N V ; Krupenko, N I ; Krupenko, S A
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2010-11, Vol.29 (47), p.6233-6244
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Loss of pleckstrin homology domain and leucine-rich repeat protein phosphatase 2 has protective effects on high glucose-injured retinal ganglion cells via the effect on the Akt–GSK–3β–Nrf2 pathway
Author / Creator:Liu, Xuan ; Liu, Yong ; Chen, Li ; Zhang, Zhichao ; Cui, Lijun ; Wei, Ting
Publisher:Cham: Springer International Publishing
Journal title:Inflammation research, 2023-03, Vol.72 (3), p.373-385
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Essential role of PH domain and leucine-rich repeat protein phosphatase 2 in Nrf2 suppression via modulation of Akt/GSK3β/Fyn kinase axis during oxidative hepatocellular toxicity
Author / Creator:Rizvi, F ; Shukla, S ; Kakkar, P
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2014-03, Vol.5 (3), p.e1153-e1153
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Clinicopathological effects of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors
Author / Creator:Toda-Ishii, Midori ; Akaike, Keisuke ; Suehara, Yoshiyuki ; Mukaihara, Kenta ; Kubota, Daisuke ; Kohsaka, Shinji ; Okubo, Taketo ; Mitani, Keiko ; Mogushi, Kaoru ; Takagi, Tatsuya ; Kaneko, Kazuo ; Yao, Takashi ; Saito, Tsuyoshi
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2016-11, Vol.29 (11), p.1424-1432
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Epigallocatechin gallate restores the reduction of protein phosphatase 2 A subunit B caused by middle cerebral artery occlusion
Author / Creator:Shah, Murad-Ali ; Kang, Ju-Bin ; Park, Dong-Ju ; Koh, Phil Ok
Publisher:England: BioMed Central
Journal title:Laboratory Animal Research, 2023, 39(1), , pp.26-36
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MicroRNA-27a contributes to the malignant behavior of gastric cancer cells by directly targeting PH domain and leucine-rich repeat protein phosphatase 2
Author / Creator:Ding, Lei ; Zhang, Shanyong ; Xu, Mu ; Zhang, Renwen ; Sui, Pengcheng ; Yang, Qing
Publisher:England: BioMed Central
Journal title:Journal of experimental & clinical cancer research, 2017-03, Vol.36 (1), p.45-45, Article 45
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Protein phosphatase 2 regulatory subunit B''Alpha silencing inhibits tumor cell proliferation in liver cancer
Author / Creator:Chen, Huijuan ; Xu, Jing ; Wang, Peixiao ; Shu, Qingming ; Huang, Lihong ; Guo, Jing ; Zhang, Xuyi ; Zhang, Hongying ; Wang, Ying ; Shen, Zhongyang ; Chen, Xinguo ; Zhang, Qing
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2019-12, Vol.8 (18), p.7741-7753
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MicroRNA-527 Induces Proliferation and Cell Cycle in Esophageal Squamous Cell Carcinoma Cells by Repressing PH Domain Leucine-Rich-Repeats Protein Phosphatase 2
Author / Creator:Xian, Qingjie ; Zhao, Ronglei ; Fu, Juanjuan
Publisher:United States: SAGE Publications
Journal title:Dose-response, 2020-04, Vol.18 (2), p.1559325820928687
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A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores
Author / Creator:Allan, Lindsey A. ; Corno, Andrea ; Valverde, Juan Manuel ; Toth, Rachel ; Ly, Tony ; Saurin, Adrian T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.3069-15, Article 3069
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Cryo-EM structure of the Hippo signaling integrator human STRIPAK
Author / Creator:Jeong, Byung-Cheon ; Bae, Sung Jun ; Ni, Lisheng ; Zhang, Xuewu ; Bai, Xiao-chen ; Luo, Xuelian
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2021-03, Vol.28 (3), p.290-299
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Protein phosphatase 2A promotes stomatal development by stabilizing SPEECHLESS in Arabidopsis
Author / Creator:Bian, Chao ; Guo, Xiaoyu ; Zhang, Yi ; Wang, Lu ; Xu, Tongda ; DeLong, Alison ; Dong, Juan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (23), p.13127-13137
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Phosphatase PP2A is requisite for the function of regulatory T cells
Author / Creator:Apostolidis, Sokratis A ; Rodríguez-Rodríguez, Noé ; Suárez-Fueyo, Abel ; Dioufa, Nikolina ; Ozcan, Esra ; Crispín, José C ; Tsokos, Maria G ; Tsokos, George C
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2016-05, Vol.17 (5), p.556-564
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Structural basis of Integrator-dependent RNA polymerase II termination
Author / Creator:Fianu, Isaac ; Ochmann, Moritz ; Walshe, James L. ; Dybkov, Olexandr ; Cruz, Joseph Neos ; Urlaub, Henning ; Cramer, Patrick
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2024-05, Vol.629 (8010), p.219-227
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Cancer-Associated Mutations in Endometriosis without Cancer
Author / Creator:Anglesio, Michael S ; Papadopoulos, Nickolas ; Ayhan, Ayse ; Nazeran, Tayyebeh M ; Noë, Michaël ; Horlings, Hugo M ; Lum, Amy ; Jones, Siân ; Senz, Janine ; Seckin, Tamer ; Ho, Julie ; Wu, Ren-Chin ; Lac, Vivian ; Ogawa, Hiroshi ; Tessier-Cloutier, Basile ; Alhassan, Rami ; Wang, Amy ; Wang, Yuxuan ; Cohen, Joshua D ; Wong, Fontayne ; Hasanovic, Adnan ; Orr, Natasha ; Zhang, Ming ; Popoli, Maria ; McMahon, Wyatt ; Wood, Laura D ; Mattox, Austin ; Allaire, Catherine ; Segars, James ; Williams, Christina ; Tomasetti, Cristian ; Boyd, Niki ; Kinzler, Kenneth W ; Gilks, C. Blake ; Diaz, Luis ; Wang, Tian-Li ; Vogelstein, Bert ; Yong, Paul J ; Huntsman, David G ; Shih, Ie-Ming
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-05, Vol.376 (19), p.1835-1848
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In vivo discovery of immunotherapy targets in the tumour microenvironment
Author / Creator:Zhou, Penghui ; Shaffer, Donald R. ; Alvarez Arias, Diana A. ; Nakazaki, Yukoh ; Pos, Wouter ; Torres, Alexis J. ; Cremasco, Viviana ; Dougan, Stephanie K. ; Cowley, Glenn S. ; Elpek, Kutlu ; Brogdon, Jennifer ; Lamb, John ; Turley, Shannon J. ; Ploegh, Hidde L. ; Root, David E. ; Love, J. Christopher ; Dranoff, Glenn ; Hacohen, Nir ; Cantor, Harvey ; Wucherpfennig, Kai W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-02, Vol.506 (7486), p.52-57
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Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification
Author / Creator:Hein, Jamin B ; Nguyen, Hieu T ; Garvanska, Dimitriya H ; Nasa, Isha ; Kruse, Thomas ; Feng, Yinnian ; Lopez Mendez, Blanca ; Davey, Norman ; Kettenbach, Arminja N ; Fordyce, Polly M ; Nilsson, Jakob
Publisher:England: EMBO Press
Journal title:Molecular systems biology, 2023-12, Vol.19 (12), p.e11782-n/a
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ArticlesPeer ReviewedFull Text
Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer
Author / Creator:Janghorban, Mahnaz ; Farrell, Amy S. ; Allen-Petersen, Brittany L. ; Pelz, Carl ; Daniel, Colin J. ; Oddo, Jessica ; Langer, Ellen M. ; Christensen, Dale J. ; Sears, Rosalie C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (25), p.9157-9162
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Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A
Author / Creator:Gharbi-Ayachi, Aicha ; Labbé, Jean-Claude ; Burgess, Andrew ; Vigneron, Suzanne ; Strub, Jean-Marc ; Brioudes, Estelle ; Van-Dorsselaer, Alain ; Castro, Anna ; Lorca, Thierry
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-12, Vol.330 (6011), p.1673-1677
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Showing 1 to 20 of 1,270 results

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SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

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The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity

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ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A

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Loss of pleckstrin homology domain and leucine-rich repeat protein phosphatase 2 has protective effects on high glucose-injured retinal ganglion cells via the effect on the Akt–GSK–3β–Nrf2 pathway

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Essential role of PH domain and leucine-rich repeat protein phosphatase 2 in Nrf2 suppression via modulation of Akt/GSK3β/Fyn kinase axis during oxidative hepatocellular toxicity

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Clinicopathological effects of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors

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Epigallocatechin gallate restores the reduction of protein phosphatase 2 A subunit B caused by middle cerebral artery occlusion

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MicroRNA-27a contributes to the malignant behavior of gastric cancer cells by directly targeting PH domain and leucine-rich repeat protein phosphatase 2

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Protein phosphatase 2 regulatory subunit B''Alpha silencing inhibits tumor cell proliferation in liver cancer

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MicroRNA-527 Induces Proliferation and Cell Cycle in Esophageal Squamous Cell Carcinoma Cells by Repressing PH Domain Leucine-Rich-Repeats Protein Phosphatase 2

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A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores

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Cryo-EM structure of the Hippo signaling integrator human STRIPAK

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Protein phosphatase 2A promotes stomatal development by stabilizing SPEECHLESS in Arabidopsis

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Phosphatase PP2A is requisite for the function of regulatory T cells

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Structural basis of Integrator-dependent RNA polymerase II termination

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Cancer-Associated Mutations in Endometriosis without Cancer

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In vivo discovery of immunotherapy targets in the tumour microenvironment

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Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification

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Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer

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Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

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