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111 results for Protein+Phosphatase+2+-+antagonists+

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ArticlesPeer ReviewedFull Text
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
Author / Creator:Mazur, Pawel K. ; Reynoird, Nicolas ; Khatri, Purvesh ; Jansen, Pascal W. T. C. ; Wilkinson, Alex W. ; Liu, Shichong ; Barbash, Olena ; Van Aller, Glenn S. ; Huddleston, Michael ; Dhanak, Dashyant ; Tummino, Peter J. ; Kruger, Ryan G. ; Garcia, Benjamin A. ; Butte, Atul J. ; Vermeulen, Michiel ; Sage, Julien ; Gozani, Or
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-06, Vol.510 (7504), p.283-287
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The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity
Author / Creator:Collison, Adam ; Hatchwell, Luke ; Verrills, Nicole ; Wark, Peter A B ; de Siqueira, Ana Pereira ; Tooze, Melinda ; Carpenter, Helen ; Don, Anthony S ; Morris, Jonathan C ; Zimmermann, Nives ; Bartlett, Nathan W ; Rothenberg, Marc E ; Johnston, Sebastian L ; Foster, Paul S ; Mattes, Joerg
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2013-02, Vol.19 (2), p.232-237
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ArticlesPeer ReviewedFull Text
ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A
Author / Creator:Oleinik, N V ; Krupenko, N I ; Krupenko, S A
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2010-11, Vol.29 (47), p.6233-6244
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Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2A That Is Essential for Mitosis
Author / Creator:Mochida, Satoru ; Maslen, Sarah L ; Skehel, Mark ; Hunt, Tim
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-12, Vol.330 (6011), p.1670-1673
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MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors
Author / Creator:Liu, Xi ; Sempere, Lorenzo F. ; Ouyang, Haoxu ; Memoli, Vincent A. ; Andrew, Angeline S. ; Luo, Yue ; Demidenko, Eugene ; Korc, Murray ; Shi, Wei ; Preis, Meir ; Dragnev, Konstantin H. ; Li, Hua ; DiRenzo, James ; Bak, Mads ; Freemantle, Sarah J. ; Kauppinen, Sakari ; Dmitrovsky, Ethan
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2010-04, Vol.120 (4), p.1298-1309
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Protein Phosphatase 2A Reduces Cigarette Smoke–induced Cathepsin S and Loss of Lung Function
Author / Creator:Doherty, Declan F. ; Nath, Sridesh ; Poon, Justin ; Foronjy, Robert F. ; Ohlmeyer, Michael ; Dabo, Abdoulaye J. ; Salathe, Matthias ; Birrell, Mark ; Belvisi, Maria ; Baumlin, Nathalie ; Kim, Michael D. ; Weldon, Sinéad ; Taggart, Clifford ; Geraghty, Patrick
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2019-07, Vol.200 (1), p.51-62
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ArticlesPeer ReviewedFull Text
Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer
Author / Creator:Janghorban, Mahnaz ; Farrell, Amy S. ; Allen-Petersen, Brittany L. ; Pelz, Carl ; Daniel, Colin J. ; Oddo, Jessica ; Langer, Ellen M. ; Christensen, Dale J. ; Sears, Rosalie C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (25), p.9157-9162
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Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A
Author / Creator:Gharbi-Ayachi, Aicha ; Labbé, Jean-Claude ; Burgess, Andrew ; Vigneron, Suzanne ; Strub, Jean-Marc ; Brioudes, Estelle ; Van-Dorsselaer, Alain ; Castro, Anna ; Lorca, Thierry
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-12, Vol.330 (6011), p.1673-1677
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UBE3A-mediated PTPA ubiquitination and degradation regulate PP2A activity and dendritic spine morphology
Author / Creator:Wang, Jie ; Lou, Sen-Sen ; Wang, Tingting ; Wu, Rong-Jie ; Li, Guangying ; Zhao, Miao ; Lu, Bin ; Li, Yi-Yan ; Zhang, Jing ; Cheng, Xuewen ; Shen, Ya ; Wang, Xing ; Zhu, Zhi-Chuan ; Li, Ming-Jie ; Takumi, Toru ; Yang, Hui ; Yu, Xiang ; Liao, Lujian ; Xiong, Zhi-Qi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (25), p.12500-12505
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A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores
Author / Creator:Allan, Lindsey A. ; Corno, Andrea ; Valverde, Juan Manuel ; Toth, Rachel ; Ly, Tony ; Saurin, Adrian T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.3069-15, Article 3069
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Protein phosphatase 2A promotes stomatal development by stabilizing SPEECHLESS in Arabidopsis
Author / Creator:Bian, Chao ; Guo, Xiaoyu ; Zhang, Yi ; Wang, Lu ; Xu, Tongda ; DeLong, Alison ; Dong, Juan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (23), p.13127-13137
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SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK
Author / Creator:Bae, Sung Jun ; Ni, Lisheng ; Osinski, Adam ; Tomchick, Diana R ; Brautigam, Chad A ; Luo, Xuelian
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2017-10, Vol.6 (10, 2017)
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ArticlesPeer ReviewedFull Text
Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways
Author / Creator:Kim, Seong M. ; Roy, Saurabh G. ; Chen, Bin ; Nguyen, Tiffany M. ; McMonigle, Ryan J. ; McCracken, Alison N. ; Zhang, Yanling ; Kofuji, Satoshi ; Hou, Jue ; Selwan, Elizabeth ; Finicle, Brendan T. ; Nguyen, Tricia T. ; Ravi, Archna ; Ramirez, Manuel U. ; Wiher, Tim ; Guenther, Garret G. ; Kono, Mari ; Sasaki, Atsuo T. ; Weisman, Lois S. ; Potma, Eric O. ; Tromberg, Bruce J. ; Edwards, Robert A. ; Hanessian, Stephen ; Edinger, Aimee L.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2016-11, Vol.126 (11), p.4088-4102
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Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade
Author / Creator:Ho, Winson S. ; Wang, Herui ; Maggio, Dominic ; Kovach, John S. ; Zhang, Qi ; Song, Qi ; Marincola, Francesco M. ; Heiss, John D. ; Gilbert, Mark R. ; Lu, Rongze ; Zhuang, Zhengping
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-05, Vol.9 (1), p.2126-15, Article 2126
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ArticlesPeer ReviewedFull Text
Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex
Author / Creator:Schweiger, Susann ; Matthes, Frank ; Posey, Karen ; Kickstein, Eva ; Weber, Stephanie ; Hettich, Moritz M. ; Pfurtscheller, Sandra ; Ehninger, Dan ; Schneider, Rainer ; Krauß, Sybille
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-10, Vol.7 (1), p.13753-13, Article 13753
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ArticlesPeer ReviewedFull Text
EMT Inducers Catalyze Malignant Transformation of Mammary Epithelial Cells and Drive Tumorigenesis towards Claudin-Low Tumors in Transgenic Mice
Author / Creator:Morel, Anne-Pierre ; Hinkal, George W. ; Thomas, Clémence ; Fauvet, Frédérique ; Courtois-Cox, Stéphanie ; Wierinckx, Anne ; Devouassoux-Shisheboran, Mojgan ; Treilleux, Isabelle ; Tissier, Agnès ; Gras, Baptiste ; Pourchet, Julie ; Puisieux, Isabelle ; Browne, Gareth J. ; Spicer, Douglas B. ; Lachuer, Joël ; Ansieau, Stéphane ; Puisieux, Alain
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2012-05, Vol.8 (5), p.e1002723
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ArticlesPeer ReviewedFull Text
Protein phosphatase 2A (PP2A): a key phosphatase in the progression of chronic obstructive pulmonary disease (COPD) to lung cancer
Author / Creator:Nader, Cassandra P. ; Cidem, Aylin ; Verrills, Nicole M. ; Ammit, Alaina J.
Publisher:England: BioMed Central
Journal title:Respiratory research, 2019-10, Vol.20 (1), p.222-222, Article 222
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ArticlesPeer ReviewedFull Text
Rescue of GABAB and GIRK function in the lateral habenula by protein phosphatase 2A inhibition ameliorates depression-like phenotypes in mice
Author / Creator:Lecca, Salvatore ; Pelosi, Assunta ; Tchenio, Anna ; Moutkine, Imane ; Lujan, Rafael ; Hervé, Denis ; Mameli, Manuel
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-03, Vol.22 (3), p.254-261
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STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism
Author / Creator:Bae, Sung Jun ; Ni, Lisheng ; Luo, Xuelian
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-04, Vol.9
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Inhibition of protein phosphatase-2A with LB-100 enhances antitumor immunity against glioblastoma
Author / Creator:Maggio, Dominic ; Ho, Winson S. ; Breese, Rebecca ; Walbridge, Stuart ; Wang, Herui ; Cui, Jing ; Heiss, John D. ; Gilbert, Mark R. ; Kovach, John S. ; Lu, Rongze O. ; Zhuang, Zhengping
Publisher:New York: Springer US
Journal title:Journal of neuro-oncology, 2020-06, Vol.148 (2), p.231-244
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Showing 1 to 20 of 111 results

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SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

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The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity

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ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A

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Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2A That Is Essential for Mitosis

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MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors

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Protein Phosphatase 2A Reduces Cigarette Smoke–induced Cathepsin S and Loss of Lung Function

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Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer

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Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

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UBE3A-mediated PTPA ubiquitination and degradation regulate PP2A activity and dendritic spine morphology

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A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores

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Protein phosphatase 2A promotes stomatal development by stabilizing SPEECHLESS in Arabidopsis

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SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK

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Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways

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Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade

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Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex

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EMT Inducers Catalyze Malignant Transformation of Mammary Epithelial Cells and Drive Tumorigenesis towards Claudin-Low Tumors in Transgenic Mice

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Protein phosphatase 2A (PP2A): a key phosphatase in the progression of chronic obstructive pulmonary disease (COPD) to lung cancer

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Rescue of GABAB and GIRK function in the lateral habenula by protein phosphatase 2A inhibition ameliorates depression-like phenotypes in mice

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STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism

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Inhibition of protein phosphatase-2A with LB-100 enhances antitumor immunity against glioblastoma

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