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PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
Author / Creator:Brasó-Maristany, Fara ; Filosto, Simone ; Catchpole, Steven ; Marlow, Rebecca ; Quist, Jelmar ; Francesch-Domenech, Erika ; Plumb, Darren A ; Zakka, Leila ; Gazinska, Patrycja ; Liccardi, Gianmaria ; Meier, Pascal ; Gris-Oliver, Albert ; Cheang, Maggie Chon U ; Perdrix-Rosell, Anna ; Shafat, Manar ; Noël, Elodie ; Patel, Nirmesh ; McEachern, Kristen ; Scaltriti, Maurizio ; Castel, Pau ; Noor, Farzana ; Buus, Richard ; Mathew, Sumi ; Watkins, Johnathan ; Serra, Violeta ; Marra, Pierfrancesco ; Grigoriadis, Anita ; Tutt, Andrew N
Publisher:London: Nature Publishing Group UK
Journal title:Nature medicine, 2016-11, Vol.22 (11), p.1303-1313
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Targeting Pim kinases in hematological cancers: molecular and clinical review
Author / Creator:Bellon, Marcia ; Nicot, Christophe
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2023-01, Vol.22 (1), p.18-18, Article 18
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The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells
Author / Creator:Blanco, F F ; Jimbo, M ; Wulfkuhle, J ; Gallagher, I ; Deng, J ; Enyenihi, L ; Meisner-Kober, N ; Londin, E ; Rigoutsos, I ; Sawicki, J A ; Risbud, M V ; Witkiewicz, A K ; McCue, P A ; Jiang, W ; Rui, H ; Yeo, C J ; Petricoin, E ; Winter, J M ; Brody, J R
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2016-05, Vol.35 (19), p.2529-2541
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Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach
Author / Creator:Shafie, Alaa ; Khan, Shama ; Batra, Sagar ; Anjum, Farah ; Mohammad, Taj ; Alam, Shoaib ; Yadav, Dharmendra Kumar ; Islam, Asimul ; Hassan, Md Imtaiyaz
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-10, Vol.16 (10), p.e0258929
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Gene expression in circulating tumor cells reveals a dynamic role of EMT and PD-L1 during osimertinib treatment in NSCLC patients
Author / Creator:Ntzifa, Aliki ; Strati, Areti ; Kallergi, Galatea ; Kotsakis, Athanasios ; Georgoulias, Vassilis ; Lianidou, Evi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-01, Vol.11 (1), p.2313-2313, Article 2313
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Genetic ablation of Pim1 or pharmacologic inhibition with TP-3654 ameliorates myelofibrosis in murine models
Author / Creator:Dutta, Avik ; Nath, Dipmoy ; Yang, Yue ; Le, Bao T. ; Rahman, Mohammad Ferdous-Ur ; Faughnan, Patrick ; Wang, Zhenjia ; Stuver, Matthew ; He, Rongquan ; Tan, Wuwei ; Hutchison, Robert E. ; Foulks, Jason M. ; Warner, Steven L. ; Zang, Chongzhi ; Mohi, Golam
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2022-03, Vol.36 (3), p.746-759
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The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing
Author / Creator:Vater, I ; Montesinos-Rongen, M ; Schlesner, M ; Haake, A ; Purschke, F ; Sprute, R ; Mettenmeyer, N ; Nazzal, I ; Nagel, I ; Gutwein, J ; Richter, J ; Buchhalter, I ; Russell, R B ; Wiestler, O D ; Eils, R ; Deckert, M ; Siebert, R
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2015-03, Vol.29 (3), p.677-685
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MicroRNA‐124‐3p regulates cell proliferation, invasion, apoptosis, and bioenergetics by targeting PIM1 in astrocytoma
Author / Creator:Deng, Danni ; Wang, Lei ; Chen, Yao ; Li, Bowen ; Xue, Lian ; Shao, Naiyuan ; Wang, Qiang ; Xia, Xiwei ; Yang, Yilin ; Zhi, Feng
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2016-07, Vol.107 (7), p.899-907
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Long non‐coding RNA SNHG16 promotes proliferation and inhibits apoptosis of diffuse large B‐cell lymphoma cells by targeting miR‐497‐5p/PIM1 axis
Author / Creator:Zhu, Qiaojuan ; Li, Yazhao ; Guo, Yang ; Hu, Linjun ; Xiao, Zunqiang ; Liu, Xin ; Wang, Jiahui ; Xu, Qiuran ; Tong, Xiangmin
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2019-11, Vol.23 (11), p.7395-7405
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Pim1 supports human colorectal cancer growth during glucose deprivation by enhancing the Warburg effect
Author / Creator:Zhang, Meng ; Liu, Tingting ; Sun, Hui ; Weng, Weiwei ; Zhang, Qiongyan ; Liu, Chenchen ; Han, Yang ; Sheng, Weiqi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2018-05, Vol.109 (5), p.1468-1479
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PIM1 promotes hepatic conversion by suppressing reprogramming-induced ferroptosis and cell cycle arrest
Author / Creator:Yuan, Yangyang ; Wang, Chenwei ; Zhuang, Xuran ; Lin, Shaofeng ; Luo, Miaomiao ; Deng, Wankun ; Zhou, Jiaqi ; Liu, Lihui ; Mao, Lina ; Peng, Wenbo ; Chen, Jian ; Wang, Qiangsong ; Shu, Yilai ; Xue, Yu ; Huang, Pengyu
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-09, Vol.13 (1), p.5237-19, Article 5237
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Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors
Author / Creator:Casillas, Andrea L. ; Chauhan, Shailender S. ; Toth, Rachel K. ; Sainz, Alva G. ; Clements, Amber N. ; Jensen, Corbin C. ; Langlais, Paul R. ; Miranti, Cindy K. ; Cress, Anne E. ; Warfel, Noel A.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2021-08, Vol.40 (32), p.5142-5152
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PIM1 is responsible for IL-6-induced breast cancer cell EMT and stemness via c-myc activation
Author / Creator:Gao, Xueqiang ; Liu, Xiangping ; Lu, Yangyong ; Wang, Yu ; Cao, Weihong ; Liu, Xiaoyi ; Hu, Haiyan ; Wang, Haibo
Publisher:Tokyo: Springer Japan
Journal title:Breast cancer (Tokyo, Japan), 2019-09, Vol.26 (5), p.663-671
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Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities
Author / Creator:Coppé, Jean-Philippe ; Mori, Miki ; Pan, Bo ; Yau, Christina ; Wolf, Denise M. ; Ruiz-Saenz, Ana ; Brunen, Diede ; Prahallad, Anirudh ; Cornelissen-Steijger, Paulien ; Kemper, Kristel ; Posch, Christian ; Wang, Changjun ; Dreyer, Courtney A. ; Krijgsman, Oscar ; Lee, Pei Rong Evelyn ; Chen, Zhongzhong ; Peeper, Daniel S. ; Moasser, Mark M. ; Bernards, René ; van ‘t Veer, Laura J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2019-06, Vol.21 (6), p.778-790
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Topoisomerase Inhibitors and PIM1 Kinase Inhibitors Improve Gene Editing Efficiency Mediated by CRISPR-Cas9 and Homology-Directed Repair
Author / Creator:Yun, Ying ; Wang, Min ; Guo, Shimeng ; Xie, Xin
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-06, Vol.29 (12), p.2890
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PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling
Author / Creator:Moody, S E ; Schinzel, A C ; Singh, S ; Izzo, F ; Strickland, M R ; Luo, L ; Thomas, S R ; Boehm, J S ; Kim, S Y ; Wang, Z C ; Hahn, W C
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2015-04, Vol.34 (16), p.2061-2071
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PIM1 instigates endothelial-to-mesenchymal transition to aggravate atherosclerosis
Author / Creator:Xue, Zhiwei ; Han, Mengtao ; Sun, Tao ; Wu, Yanzhao ; Xing, Wenchen ; Mu, Feiyu ; Zhang, Zhihan ; Liu, Junzhi ; Liang, Xiangjun ; Ling, Lu ; Wang, Jian ; Wang, Jiwei ; Li, Xingang ; Huang, Bin ; Wang, Donghai
Publisher:Australia: Ivyspring International Publisher
Journal title:Theranostics, 2025, Vol.15 (2), p.745-765
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miR24‐2 accelerates progression of liver cancer cells by activating Pim1 through tri‐methylation of Histone H3 on the ninth lysine
Author / Creator:Yang, Yuxin ; Song, Shuting ; Meng, Qiuyu ; Wang, Liyan ; Li, Xiaonan ; Xie, Sijie ; Chen, Yingjie ; Jiang, Xiaoxue ; Wang, Chen ; Lu, Yanan ; Xin, Xiaoru ; Pu, Hu ; Gui, Xin ; Li, Tianming ; Xu, Jie ; Li, Jiao ; Jia, Song ; Lu, Dongdong
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2020-03, Vol.24 (5), p.2772-2790
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The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status
Author / Creator:Trigg, Ricky M. ; Lee, Liam C. ; Prokoph, Nina ; Jahangiri, Leila ; Reynolds, C. Patrick ; Amos Burke, G. A. ; Probst, Nicola A. ; Han, Miaojun ; Matthews, Jamie D. ; Lim, Hong Kai ; Manners, Eleanor ; Martinez, Sonia ; Pastor, Joaquin ; Blanco-Aparicio, Carmen ; Merkel, Olaf ; de los Fayos Alonso, Ines Garces ; Kodajova, Petra ; Tangermann, Simone ; Högler, Sandra ; Luo, Ji ; Kenner, Lukas ; Turner, Suzanne D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-11, Vol.10 (1), p.5428-13, Article 5428
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PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer
Author / Creator:Luszczak, Sabina ; Kumar, Christopher ; Sathyadevan, Vignesh Krishna ; Simpson, Benjamin S ; Gately, Kathy A ; Whitaker, Hayley C ; Heavey, Susan
Publisher:England: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2020-01, Vol.5 (1), p.7
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PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer

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Targeting Pim kinases in hematological cancers: molecular and clinical review

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The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells

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Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach

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Gene expression in circulating tumor cells reveals a dynamic role of EMT and PD-L1 during osimertinib treatment in NSCLC patients

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Genetic ablation of Pim1 or pharmacologic inhibition with TP-3654 ameliorates myelofibrosis in murine models

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The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing

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MicroRNA‐124‐3p regulates cell proliferation, invasion, apoptosis, and bioenergetics by targeting PIM1 in astrocytoma

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Long non‐coding RNA SNHG16 promotes proliferation and inhibits apoptosis of diffuse large B‐cell lymphoma cells by targeting miR‐497‐5p/PIM1 axis

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Pim1 supports human colorectal cancer growth during glucose deprivation by enhancing the Warburg effect

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PIM1 promotes hepatic conversion by suppressing reprogramming-induced ferroptosis and cell cycle arrest

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Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors

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PIM1 is responsible for IL-6-induced breast cancer cell EMT and stemness via c-myc activation

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Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities

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Topoisomerase Inhibitors and PIM1 Kinase Inhibitors Improve Gene Editing Efficiency Mediated by CRISPR-Cas9 and Homology-Directed Repair

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PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling

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PIM1 instigates endothelial-to-mesenchymal transition to aggravate atherosclerosis

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miR24‐2 accelerates progression of liver cancer cells by activating Pim1 through tri‐methylation of Histone H3 on the ninth lysine

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The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status

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PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer

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