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ArticlesPeer ReviewedFull Text
Coupled Motions Direct Electrons along Human Microsomal P450 Chains
Author / Creator:Pudney, Christopher R. ; Khara, Basile ; Johannissen, Linus O. ; Scrutton, Nigel S.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2011-12, Vol.9 (12), p.e1001222-e1001222
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ArticlesPeer ReviewedFull Text
Trends in hospital presentations following analytically confirmed synthetic cannabinoid receptor agonist exposure before and after implementation of the 2016 UK Psychoactive Substances Act
Author / Creator:Craft, Sam ; Dunn, Michael ; Vidler, Dan ; Officer, Jane ; Blagbrough, Ian S. ; Pudney, Christopher R. ; Henderson, Graeme ; Abouzeid, Ahmed ; Dargan, Paul I. ; Eddleston, Michael ; Cooper, Jamie ; Hill, Simon L. ; Roper, Clair ; Freeman, Tom P. ; Thomas, Simon H. L.
Publisher:England: Blackwell Publishing Ltd
Journal title:Addiction (Abingdon, England), 2022-11, Vol.117 (11), p.2899-2906
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ArticlesFull Text
N-linked glycosylation increases horse radish peroxidase rigidity leading to enhanced activity and stability
Author / Creator:Ramakrishnan, Krithika ; Johnson, Rachel ; Winter, Samuel ; Worthy, Harley ; Thomas, Chris ; Humer, Diana ; Spadiut, Oliver ; Hindson, Sarah ; Wells, Stephen Anthony ; Barratt, Andrew ; Menzies, Georgina ; Pudney, Christopher R ; Jones, Dafydd
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-09
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ArticlesFull Text
Conformation control of the histidine kinase BceS of Bacillus subtilis by its cognate ABC-transporter facilitates need-based activation of antibiotic resistance
Author / Creator:Koh, Alan ; Gibbon, Marjorie J ; Marc W Van Der Kamp ; Pudney, Christopher R ; Gebhard, Susanne
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-09
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ArticlesFull Text
Reliable in silico ranking of engineered therapeutic TCR binding affinities using MMPBSA and MMGBSA calculations
Author / Creator:Marc W Van Der Kamp ; Crean, Rory M ; Cole, David K ; Pudney, Christopher R
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-06
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ArticlesFull Text
The Effect of Isotropic Pressure on the Electronic Structure and Superatomic Orbitals of Molecular [Ag44(SPhCOOH)30]4-, [Ag44(SPhF2)30]4- & [Ag25(SPhMe2)18]- Nanoclusters
Author / Creator:Terry, Lui R ; Pudney, Christopher R ; Gersen, Henkjan ; Hall, Simon R
Publisher:Ithaca: Cornell University Library, arXiv.org
Journal title:arXiv.org, 2018-01
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ArticlesFull Text
Structure and dynamics of a cold-active esterase reveals water entropy and active site accessibility as the likely drivers for cold-adaptation
Author / Creator:Noby, Nehad ; Husam Sabah Auhim ; Worthy, Harley ; Winter, Samuel ; Embady, Amira ; Saeed, Hesham ; Hussein, Ahmed ; Pudney, Christopher ; Rizkallah, Pierre ; Wells, Stephen Anthony ; Jones, Dafydd ; Pudney, Christopher R
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-05
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ArticlesFull Text
Rigidifying a de novo enzyme increases activity and induces a negative activation heat capacity
Author / Creator:Hindson, Sarah A ; Bunzel, Adrian H ; Frank, Bettina ; Svistunenko, Dimitri A ; Williams, Christopher ; Marc W Van Der Kamp ; Mulholland, Adrian J ; Pudney, Christopher R ; Anderson, Ross Jl
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-04
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ArticlesFull Text
A thermodynamic model for interpreting tryptophan excitation-energy-dependent fluorescence spectra provides insight into protein conformational sampling and stability
Author / Creator:Kwok, Anthony ; Camacho, Ines ; Winter, Samuel ; Knight, Michael ; Meade, Richard ; Van Der Kamp, Marc ; Turner, Alison ; O'hara, John ; Mason, Jody ; Jones, Alex R ; Vickery Arcus ; Pudney, Christopher R
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-09
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ArticlesFull Text
Chemical mapping exposes the importance of active site interactions in governing the temperature dependence of enzyme turnover
Author / Creator:Winter, Samuel D ; Jones, Hannah Bl ; Rasadean, Dora ; Crean, Rory ; Danson, Michael J ; Pantos, Dan ; Katona, Gergely ; Prentice, Erica ; Vickery Arcus ; Van Der Kamp, Marc ; Pudney, Christopher R
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-06
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ArticlesFull Text
Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift
Author / Creator:Knight, Michael ; Woolley, Rachel ; Kwok, Anthony ; Parsons, Stuart ; Jones, Hannah ; Gulacsy, Christina ; Phaal, Polly ; Kassaar, Omar ; Dawkins, Kieran ; Rodriguez, Elizabeth ; Marques, Andreia ; Bowsher, Leo ; Wells, Stephen Anthony ; Watts, Andrew ; Jean Mh Van Den Elsen ; Turner, Alison ; Ohara, John ; Pudney, Christopher R
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-03
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Coupled Motions Direct Electrons along Human Microsomal P450 Chains

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Trends in hospital presentations following analytically confirmed synthetic cannabinoid receptor agonist exposure before and after implementation of the 2016 UK Psychoactive Substances Act

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N-linked glycosylation increases horse radish peroxidase rigidity leading to enhanced activity and stability

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Conformation control of the histidine kinase BceS of Bacillus subtilis by its cognate ABC-transporter facilitates need-based activation of antibiotic resistance

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Reliable in silico ranking of engineered therapeutic TCR binding affinities using MMPBSA and MMGBSA calculations

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The Effect of Isotropic Pressure on the Electronic Structure and Superatomic Orbitals of Molecular [Ag44(SPhCOOH)30]4-, [Ag44(SPhF2)30]4- & [Ag25(SPhMe2)18]- Nanoclusters

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Structure and dynamics of a cold-active esterase reveals water entropy and active site accessibility as the likely drivers for cold-adaptation

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Rigidifying a de novo enzyme increases activity and induces a negative activation heat capacity

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A thermodynamic model for interpreting tryptophan excitation-energy-dependent fluorescence spectra provides insight into protein conformational sampling and stability

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Chemical mapping exposes the importance of active site interactions in governing the temperature dependence of enzyme turnover

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Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift

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