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ArticlesPeer ReviewedFull Text
Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial
Author / Creator:Delany-Moretlwe, Sinead ; Hughes, James P ; Bock, Peter ; Hunidzarira, Portia ; Kalonji, Dishiki ; Kayange, Noel ; Makhema, Joseph ; Mandima, Patricia ; Mathew, Carrie ; Spooner, Elizabeth ; Mpendo, Juliet ; Mukwekwerere, Pamela ; Mgodi, Nyaradzo ; Ntege, Patricia Nahirya ; Nakabiito, Clemensia ; Nuwagaba-Biribonwoha, Harriet ; Panchia, Ravindre ; Singh, Nishanta ; Farrior, Jennifer ; Rose, Scott ; Anderson, Peter L ; Eshleman, Susan H ; Marzinke, Mark A ; Hendrix, Craig W ; Beigel-Orme, Stephanie ; Hosek, Sybil ; Tolley, Elizabeth ; Sista, Nirupama ; Adeyeye, Adeola ; Rooney, James F ; Rinehart, Alex ; Spreen, William R ; Hanscom, Brett ; Cohen, Myron S ; Hosseinipour, Mina C ; Asmelash, Aida ; Sehurutshi, Alice ; Baguma, Allan ; Marais, Anita ; Kawoozo, Barbarah ; Malinga, Bongiwe Prudence ; Mirembe, Brenda Gati ; Okech, Brenda ; Esterhuizen, Bryan ; Murombedzi, Caroline ; Gadama, Daphne ; Hwengwere, Eldinah ; Roos, Elizabeth ; Magada, Elizabeth S ; Shava, Emily ; Piwowar-Manning, Estelle ; Tahuringana, Eunice ; Muhlanga, Felix GS ; Conradie, Francesca ; Angira, Frank ; Nanyonjo, Gertrude ; Kistnasami, Girisha ; Naidoo, Ishana ; Horak, Jaco ; Jere, Jane ; Moodley, Jeeva ; Shin, Katie ; Nel, Kerry ; Bokoch, Kevin ; Birungi, Lilian ; Emel, Lynda ; Monametsi, Maletsatsi ; Sibanda, Marvelous ; Chitukuta, Miria ; Matimbira, Moleen ; Sibisi, Ncamsile ; Mudzonga, Netsai ; Natureeba, Paul ; Richardson, Paul ; Musara, Petina ; Macdonald, Pippa ; Nkambule, Rejoice ; Mosime, Repelang ; White, Rhonda ; Berhanu, Ribka ; Ncube-Sihlongonyane, Ritha ; Sekabira, Rogers ; Siva, Samantha ; Pillay, Saresha ; Govender, Shamelle ; Bamweyana, Sheiala ; Innes, Steve ; Dadabhai, Sufia ; Samandari, Taraz ; Tembo, Tchangani ; Lungu Mabedi, Thandie ; Chirenda, Thandiwe ; Chidemo, Tinashe ; Mudhune, Victor ; Naidoo, Vikesh ; Samaneka, Wadzanai ; Agyei, Yaw ; Musodza, Yeukai ; Fourie, Yolandie ; Gaffoor, Zakir
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2022-05, Vol.399 (10337), p.1779-1789
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Apixaban to Prevent Venous Thromboembolism in Patients with Cancer
Author / Creator:Carrier, Marc ; Abou-Nassar, Karim ; Mallick, Ranjeeta ; Tagalakis, Vicky ; Shivakumar, Sudeep ; Schattner, Ariah ; Kuruvilla, Philip ; Hill, Danny ; Spadafora, Silvana ; Marquis, Katerine ; Trinkaus, Mateya ; Tomiak, Anna ; Lee, Agnes Y.Y ; Gross, Peter L ; Lazo-Langner, Alejandro ; El-Maraghi, Robert ; Goss, Glenwood ; Le Gal, Gregoire ; Stewart, David ; Ramsay, Timothy ; Rodger, Marc ; Witham, Debra ; Wells, Philip S
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-02, Vol.380 (8), p.711-719
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Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial
Author / Creator:Margolis, David A ; Gonzalez-Garcia, Juan ; Stellbrink, Hans-Jürgen ; Eron, Joseph J ; Yazdanpanah, Yazdan ; Podzamczer, Daniel ; Lutz, Thomas ; Angel, Jonathan B ; Richmond, Gary J ; Clotet, Bonaventura ; Gutierrez, Felix ; Sloan, Louis ; Clair, Marty St ; Murray, Miranda ; Ford, Susan L ; Mrus, Joseph ; Patel, Parul ; Crauwels, Herta ; Griffith, Sandy K ; Sutton, Kenneth C ; Dorey, David ; Smith, Kimberly Y ; Williams, Peter E ; Spreen, William R
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-09, Vol.390 (10101), p.1499-1510
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Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation
Author / Creator:Lopes, Renato D ; Heizer, Gretchen ; Aronson, Ronald ; Vora, Amit N ; Massaro, Tyler ; Mehran, Roxana ; Goodman, Shaun G ; Windecker, Stephan ; Darius, Harald ; Li, Jia ; Averkov, Oleg ; Bahit, M. Cecilia ; Berwanger, Otavio ; Budaj, Andrzej ; Hijazi, Ziad ; Parkhomenko, Alexander ; Sinnaeve, Peter ; Storey, Robert F ; Thiele, Holger ; Vinereanu, Dragos ; Granger, Christopher B ; Alexander, John H
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-04, Vol.380 (16), p.1509-1524
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ArticlesPeer ReviewedFull Text
Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma
Author / Creator:Long, Georgina V ; Hauschild, Axel ; Santinami, Mario ; Atkinson, Victoria ; Mandalà, Mario ; Chiarion-Sileni, Vanna ; Larkin, James ; Nyakas, Marta ; Dutriaux, Caroline ; Haydon, Andrew ; Robert, Caroline ; Mortier, Laurent ; Schachter, Jacob ; Schadendorf, Dirk ; Lesimple, Thierry ; Plummer, Ruth ; Ji, Ran ; Zhang, Pingkuan ; Mookerjee, Bijoyesh ; Legos, Jeff ; Kefford, Richard ; Dummer, Reinhard ; Kirkwood, John M
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-11, Vol.377 (19), p.1813-1823
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ArticlesPeer ReviewedFull Text
Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity
Author / Creator:Siegal, Deborah M ; Curnutte, John T ; Connolly, Stuart J ; Lu, Genmin ; Conley, Pamela B ; Wiens, Brian L ; Mathur, Vandana S ; Castillo, Janice ; Bronson, Michele D ; Leeds, Janet M ; Mar, Florie A ; Gold, Alex ; Crowther, Mark A
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2015-12, Vol.373 (25), p.2413-2424
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ArticlesPeer ReviewedFull Text
A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis
Author / Creator:King, Talmadge E ; Bradford, Williamson Z ; Castro-Bernardini, Socorro ; Fagan, Elizabeth A ; Glaspole, Ian ; Glassberg, Marilyn K ; Gorina, Eduard ; Hopkins, Peter M ; Kardatzke, David ; Lancaster, Lisa ; Lederer, David J ; Nathan, Steven D ; Pereira, Carlos A ; Sahn, Steven A ; Sussman, Robert ; Swigris, Jeffrey J ; Noble, Paul W
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-05, Vol.370 (22), p.2083-2092
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ArticlesPeer ReviewedFull Text
Targeting EZH2 in cancer
Author / Creator:Kim, Kimberly H ; Roberts, Charles W M
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-02, Vol.22 (2), p.128-134
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The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study
Author / Creator:Hijazi, Ziad, Dr ; Oldgren, Jonas, PhD ; Lindbäck, Johan, MSc ; Alexander, John H, Prof ; Connolly, Stuart J, Prof ; Eikelboom, John W, MD ; Ezekowitz, Michael D, Prof ; Held, Claes, PhD ; Hylek, Elaine M, Prof ; Lopes, Renato D, PhD ; Siegbahn, Agneta, Prof ; Yusuf, Salim, Prof ; Granger, Christopher B, Prof ; Wallentin, Lars, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-06, Vol.387 (10035), p.2302-2311
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ArticlesPeer ReviewedFull Text
Pirfenidone in heart failure with preserved ejection fraction: a randomized phase 2 trial
Author / Creator:Lewis, Gavin A. ; Dodd, Susanna ; Clayton, Dannii ; Bedson, Emma ; Eccleson, Helen ; Schelbert, Erik B. ; Naish, Josephine H. ; Jimenez, Beatriz Duran ; Williams, Simon G. ; Cunnington, Colin ; Ahmed, Fozia Zahir ; Cooper, Anne ; Rajavarma Viswesvaraiah ; Russell, Stuart ; McDonagh, Theresa ; Williamson, Paula R. ; Miller, Christopher A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2021-08, Vol.27 (8), p.1477-1482
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Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis
Author / Creator:Liu, Gabrielle Y ; Budinger, G R Scott ; Dematte, Jane E
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ (Online), 2022-06, Vol.377, p.e066354-e066354
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Pirfenidone Reduces Respiratory-related Hospitalizations in Idiopathic Pulmonary Fibrosis
Author / Creator:Ley, Brett ; Swigris, Jeffrey ; Day, Bann-Mo ; Stauffer, John L ; Raimundo, Karina ; Chou, Willis ; Collard, Harold R
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2017-09, Vol.196 (6), p.756-761
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Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma
Author / Creator:Flaherty, Keith T ; Robert, Caroline ; Hersey, Peter ; Nathan, Paul ; Garbe, Claus ; Milhem, Mohammed ; Demidov, Lev V ; Hassel, Jessica C ; Rutkowski, Piotr ; Mohr, Peter ; Dummer, Reinhard ; Trefzer, Uwe ; Larkin, James M.G ; Utikal, Jochen ; Dreno, Brigitte ; Nyakas, Marta ; Middleton, Mark R ; Becker, Jürgen C ; Casey, Michelle ; Sherman, Laurie J ; Wu, Frank S ; Ouellet, Daniele ; Martin, Anne-Marie ; Patel, Kiran ; Schadendorf, Dirk
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2012-07, Vol.367 (2), p.107-114
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Nintedanib with Add-on Pirfenidone in Idiopathic Pulmonary Fibrosis. Results of the INJOURNEY Trial
Author / Creator:Vancheri, Carlo ; Kreuter, Michael ; Richeldi, Luca ; Ryerson, Christopher J ; Valeyre, Dominique ; Grutters, Jan C ; Wiebe, Sabrina ; Stansen, Wibke ; Quaresma, Manuel ; Stowasser, Susanne ; Wuyts, Wim A
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2018-02, Vol.197 (3), p.356-363
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Venous Thrombosis during Spaceflight
Author / Creator:Auñón-Chancellor, Serena M ; Pattarini, James M ; Moll, Stephan ; Sargsyan, Ashot
Publisher:United States
Journal title:The New England journal of medicine, 2020-01, Vol.382 (1), p.89
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EZH2: a novel target for cancer treatment
Author / Creator:Duan, Ran ; Du, Wenfang ; Guo, Weijian
Publisher:England: BioMed Central Ltd
Journal title:Journal of hematology and oncology, 2020-07, Vol.13 (1), p.104-12, Article 104
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ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor
Author / Creator:Li, Dong ; March, Michael E. ; Gutierrez-Uzquiza, Alvaro ; Kao, Charlly ; Seiler, Christoph ; Pinto, Erin ; Matsuoka, Leticia S. ; Battig, Mark R. ; Bhoj, Elizabeth J. ; Wenger, Tara L. ; Tian, Lifeng ; Robinson, Nora ; Wang, Tiancheng ; Liu, Yichuan ; Weinstein, Brant M. ; Swift, Matthew ; Jung, Hyun Min ; Kaminski, Courtney N. ; Chiavacci, Rosetta ; Perkins, Jonathan A. ; Levine, Michael A. ; Sleiman, Patrick M. A. ; Hicks, Patricia J. ; Strausbaugh, Janet T. ; Belasco, Jean B. ; Dori, Yoav ; Hakonarson, Hakon
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2019-07, Vol.25 (7), p.1116-1122
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Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiotherapy plus gemcitabine for locally recurrent pancreatic cancer after surgical resection: an open-label,...
Author / Creator:Zhu, Xiaofei ; Cao, Yangsen ; Liu, Wenyu ; Ju, Xiaoping ; Zhao, Xianzhi ; Jiang, Lingong ; Ye, Yusheng ; Jin, Gang ; Zhang, Huojun
Publisher:England
Journal title:The lancet oncology, 2021-08, Vol.22 (8), p.1093-1102
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Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson’s disease
Author / Creator:Martin-Bastida, Antonio ; Ward, Roberta J. ; Newbould, Rexford ; Piccini, Paola ; Sharp, David ; Kabba, Christina ; Patel, Maneesh C. ; Spino, Michael ; Connelly, John ; Tricta, Fernando ; Crichton, Robert R. ; Dexter, David T.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-05, Vol.7 (1), p.1398-9, Article 1398
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Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with idiopathic pulmonary fibro...
Author / Creator:Nathan, Steven D ; Albera, Carlo ; Bradford, Williamson Z ; Costabel, Ulrich ; du Bois, Roland M ; Fagan, Elizabeth A ; Fishman, Robert S ; Glaspole, Ian ; Glassberg, Marilyn K ; Glasscock, Kenneth F ; King, Talmadge E ; Lancaster, Lisa ; Lederer, David J ; Lin, Zhengning ; Pereira, Carlos A ; Swigris, Jeffrey J ; Valeyre, Dominique ; Noble, Paul W ; Wells, Athol U
Publisher:England: BMJ Publishing Group LTD
Journal title:Thorax, 2016-05, Vol.71 (5), p.429-435
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Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial

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Apixaban to Prevent Venous Thromboembolism in Patients with Cancer

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Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial

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Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation

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Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma

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Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity

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A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

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Targeting EZH2 in cancer

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The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study

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Pirfenidone in heart failure with preserved ejection fraction: a randomized phase 2 trial

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Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis

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Pirfenidone Reduces Respiratory-related Hospitalizations in Idiopathic Pulmonary Fibrosis

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Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma

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Nintedanib with Add-on Pirfenidone in Idiopathic Pulmonary Fibrosis. Results of the INJOURNEY Trial

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Venous Thrombosis during Spaceflight

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EZH2: a novel target for cancer treatment

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ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor

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Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiotherapy plus gemcitabine for locally recurrent pancreatic cancer after surgical resection: an open-label,...

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Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson’s disease

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Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with idiopathic pulmonary fibro...

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