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ArticlesPeer ReviewedFull Text
Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis
Author / Creator:Sandborn, William J ; Su, Chinyu ; Sands, Bruce E ; D’Haens, Geert R ; Vermeire, Séverine ; Schreiber, Stefan ; Danese, Silvio ; Feagan, Brian G ; Reinisch, Walter ; Niezychowski, Wojciech ; Friedman, Gary ; Lawendy, Nervin ; Yu, Dahong ; Woodworth, Deborah ; Mukherjee, Arnab ; Zhang, Haiying ; Healey, Paul ; Panés, Julian
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-05, Vol.376 (18), p.1723-1736
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Ubrogepant for the Treatment of Migraine
Author / Creator:Dodick, David W ; Lipton, Richard B ; Ailani, Jessica ; Lu, Kaifeng ; Finnegan, Michelle ; Trugman, Joel M ; Szegedi, Armin
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-12, Vol.381 (23), p.2230-2241
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Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma
Author / Creator:Méjean, Arnaud ; Ravaud, Alain ; Thezenas, Simon ; Colas, Sandra ; Beauval, Jean-Baptiste ; Bensalah, Karim ; Geoffrois, Lionnel ; Thiery-Vuillemin, Antoine ; Cormier, Luc ; Lang, Hervé ; Guy, Laurent ; Gravis, Gwenaelle ; Rolland, Frederic ; Linassier, Claude ; Lechevallier, Eric ; Beisland, Christian ; Aitchison, Michael ; Oudard, Stephane ; Patard, Jean-Jacques ; Theodore, Christine ; Chevreau, Christine ; Laguerre, Brigitte ; Hubert, Jacques ; Gross-Goupil, Marine ; Bernhard, Jean-Christophe ; Albiges, Laurence ; Timsit, Marc-Olivier ; Lebret, Thierry ; Escudier, Bernard
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2018-08, Vol.379 (5), p.417-427
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Avapritinib in advanced PDGFRA D842V-mutant gastrointestinal stromal tumour (NAVIGATOR): a multicentre, open-label, phase 1 trial
Author / Creator:Heinrich, Michael C, MD ; Jones, Robin L, MD ; von Mehren, Margaret, Prof ; Schöffski, Patrick, Prof ; Serrano, César, MD ; Kang, Yoon-Koo, Prof ; Cassier, Philippe A, MD ; Mir, Olivier, MD ; Eskens, Ferry, MD ; Tap, William D, MD ; Rutkowski, Piotr, Prof ; Chawla, Sant P, MD ; Trent, Jonathan, Prof ; Tugnait, Meera, PhD ; Evans, Erica K, PhD ; Lauz, Tamieka, MS ; Zhou, Teresa, PhD ; Roche, Maria, MS ; Wolf, Beni B, MD ; Bauer, Sebastian, Prof ; George, Suzanne, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-07, Vol.21 (7), p.935-946
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Seven-day vonoprazan and low-dose amoxicillin dual therapy as first-line Helicobacter pylori treatment: a multicentre randomised trial in Japan
Author / Creator:Suzuki, Sho ; Gotoda, Takuji ; Kusano, Chika ; Ikehara, Hisatomo ; Ichijima, Ryoji ; Ohyauchi, Motoki ; Ito, Hirotaka ; Kawamura, Masashi ; Ogata, Yohei ; Ohtaka, Masahiko ; Nakahara, Moriyasu ; Kawabe, Koichi
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2020-06, Vol.69 (6), p.1019-1026
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Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial
Author / Creator:Turner, Nicholas C, Prof ; Kingston, Belinda, MB ; Kilburn, Lucy S, MSc ; Kernaghan, Sarah, BSc ; Wardley, Andrew M, Prof ; Macpherson, Iain R, MD ; Baird, Richard D, MD ; Roylance, Rebecca, MD ; Stephens, Peter, PhD ; Oikonomidou, Olga, MD ; Braybrooke, Jeremy P, FRCP ; Tuthill, Mark, MRCP ; Abraham, Jacinta, BMBS ; Winter, Matthew C, MD ; Bye, Hannah, PhD ; Hubank, Michael, PhD ; Gevensleben, Heidrun, MD ; Cutts, Ros, PhD ; Snowdon, Claire, MSc ; Rea, Daniel, Prof ; Cameron, David, Prof ; Shaaban, Abeer, PhD ; Randle, Katrina, MSc ; Martin, Sue, BSc ; Wilkinson, Katie, BSc ; Moretti, Laura, MSc ; Bliss, Judith M, Prof ; Ring, Alistair, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-10, Vol.21 (10), p.1296-1308
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ArticlesPeer ReviewedFull Text
Atogepant for the Preventive Treatment of Migraine
Author / Creator:Ailani, Jessica ; Lipton, Richard B ; Goadsby, Peter J ; Guo, Hua ; Miceli, Rosa ; Severt, Lawrence ; Finnegan, Michelle ; Trugman, Joel M
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2021-08, Vol.385 (8), p.695-706
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ArticlesPeer ReviewedFull Text
Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis
Author / Creator:Craiglow, Brittany G. ; King, Brett A.
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2014-12, Vol.134 (12), p.2988-2990
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ArticlesPeer ReviewedFull Text
Tofacitinib for Psoriatic Arthritis in Patients with an Inadequate Response to TNF Inhibitors
Author / Creator:Gladman, Dafna ; Rigby, William ; Azevedo, Valderilio F ; Behrens, Frank ; Blanco, Ricardo ; Kaszuba, Andrzej ; Kudlacz, Elizabeth ; Wang, Cunshan ; Menon, Sujatha ; Hendrikx, Thijs ; Kanik, Keith S
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-10, Vol.377 (16), p.1525-1536
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ArticlesPeer ReviewedFull Text
Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4, double-blind, head-...
Author / Creator:Fleischmann, Roy, Prof ; Mysler, Eduardo, MD ; Hall, Stephen, MD ; Kivitz, Alan J, MD ; Moots, Robert J, Prof ; Luo, Zhen, PhD ; DeMasi, Ryan, MD ; Soma, Koshika, MD ; Zhang, Richard, PhD ; Takiya, Liza, PharmD ; Tatulych, Svitlana, MD ; Mojcik, Christopher, MD ; Krishnaswami, Sriram, PhD ; Menon, Sujatha, PhD ; Smolen, Josef S, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-07, Vol.390 (10093), p.457-468
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ArticlesPeer ReviewedFull Text
The emerging safety profile of JAK inhibitors in rheumatic disease
Author / Creator:Winthrop, Kevin L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Rheumatology, 2017-04, Vol.13 (4), p.234-243
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ArticlesPeer ReviewedFull Text
Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade
Author / Creator:Zhu, Ying ; Yang, Jing ; Xu, Da ; Gao, Xiao-Mei ; Zhang, Ze ; Hsu, Jennifer L ; Li, Chia-Wei ; Lim, Seung-Oe ; Sheng, Yuan-Yuan ; Zhang, Yu ; Li, Jian-Hua ; Luo, Qin ; Zheng, Yan ; Zhao, Yue ; Lu, Lu ; Jia, Hu-Liang ; Hung, Mien-Chie ; Dong, Qiong-Zhu ; Qin, Lun-Xiu
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2019-09, Vol.68 (9), p.1653-1666
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ArticlesPeer ReviewedFull Text
Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial
Author / Creator:Bachelez, Hervé, Prof ; van de Kerkhof, Peter C M, Prof ; Strohal, Robert, Prof ; Kubanov, Alexey, Prof ; Valenzuela, Fernando, MD ; Lee, Joo-Heung, Prof ; Yakusevich, Vladimir, Prof ; Chimenti, Sergio, Prof ; Papacharalambous, Jocelyne, MD ; Proulx, James, MD ; Gupta, Pankaj, PhD ; Tan, Huaming, PhD ; Tawadrous, Margaret, MD ; Valdez, Hernan, MD ; Wolk, Robert, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2015-08, Vol.386 (9993), p.552-561
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Safety and efficacy of tofacitinib for up to 9.5 years in the treatment of rheumatoid arthritis: final results of a global, open-label, long-term extension study
Author / Creator:Wollenhaupt, Jürgen ; Lee, Eun-Bong ; Curtis, Jeffrey R ; Silverfield, Joel ; Terry, Ketti ; Soma, Koshika ; Mojcik, Chris ; DeMasi, Ryan ; Strengholt, Sander ; Kwok, Kenneth ; Lazariciu, Irina ; Wang, Lisy ; Cohen, Stanley
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2019-04, Vol.21 (1), p.89-18, Article 89
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ArticlesPeer ReviewedFull Text
Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma
Author / Creator:Motzer, Robert J ; Hutson, Thomas E ; Cella, David ; Reeves, James ; Hawkins, Robert ; Guo, Jun ; Nathan, Paul ; Staehler, Michael ; de Souza, Paul ; Merchan, Jaime R ; Boleti, Ekaterini ; Fife, Kate ; Jin, Jie ; Jones, Robert ; Uemura, Hirotsugu ; De Giorgi, Ugo ; Harmenberg, Ulrika ; Wang, Jinwan ; Sternberg, Cora N ; Deen, Keith ; McCann, Lauren ; Hackshaw, Michelle D ; Crescenzo, Rocco ; Pandite, Lini N ; Choueiri, Toni K
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2013-08, Vol.369 (8), p.722-731
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Efficacy of glucocorticoids, conventional and targeted synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the 2016 update of the EULAR recommendations for the ma...
Author / Creator:Chatzidionysiou, Katerina ; Emamikia, Sharzad ; Nam, Jackie ; Ramiro, Sofia ; Smolen, Josef ; van der Heijde, Désirée ; Dougados, Maxime ; Bijlsma, Johannes ; Burmester, Gerd ; Scholte, Marieke ; van Vollenhoven, Ronald ; Landewé, Robert
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2017-06, Vol.76 (6), p.1102-1107
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Familial chilblain lupus due to a gain-of-function mutation in STING
Author / Creator:König, Nadja ; Fiehn, Christoph ; Wolf, Christine ; Schuster, Max ; Cura Costa, Emanuel ; Tüngler, Victoria ; Alvarez, Hugo Ariel ; Chara, Osvaldo ; Engel, Kerstin ; Goldbach-Mansky, Raphaela ; Günther, Claudia ; Lee-Kirsch, Min Ae
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2017-02, Vol.76 (2), p.468-472
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Overall Survival in Renal-Cell Carcinoma with Pazopanib versus Sunitinib
Author / Creator:Motzer, Robert J ; Hutson, Thomas E ; McCann, Lauren ; Deen, Keith ; Choueiri, Toni K
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-05, Vol.370 (18), p.1769-1770
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Targeting renal cell carcinoma with a HIF-2 antagonist
Author / Creator:Chen, Wenfang ; Hill, Haley ; Christie, Alana ; Kim, Min Soo ; Holloman, Eboni ; Pavia-Jimenez, Andrea ; Homayoun, Farrah ; Ma, Yuanqing ; Patel, Nirav ; Yell, Paul ; Hao, Guiyang ; Yousuf, Qurratulain ; Joyce, Allison ; Pedrosa, Ivan ; Geiger, Heather ; Zhang, He ; Chang, Jenny ; Gardner, Kevin H. ; Bruick, Richard K. ; Reeves, Catherine ; Hwang, Tae Hyun ; Courtney, Kevin ; Frenkel, Eugene ; Sun, Xiankai ; Zojwalla, Naseem ; Wong, Tai ; Rizzi, James P. ; Wallace, Eli M. ; Josey, John A. ; Xie, Yang ; Xie, Xian-Jin ; Kapur, Payal ; McKay, Renée M. ; Brugarolas, James
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-11, Vol.539 (7627), p.112-117
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Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis
Author / Creator:Cooper, Christopher J ; Murphy, Timothy P ; Cutlip, Donald E ; Jamerson, Kenneth ; Henrich, William ; Reid, Diane M ; Cohen, David J ; Matsumoto, Alan H ; Steffes, Michael ; Jaff, Michael R ; Prince, Martin R ; Lewis, Eldrin F ; Tuttle, Katherine R ; Shapiro, Joseph I ; Rundback, John H ; Massaro, Joseph M ; D'Agostino, Ralph B ; Dworkin, Lance D
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-01, Vol.370 (1), p.13-22
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Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis

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Ubrogepant for the Treatment of Migraine

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Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma

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Avapritinib in advanced PDGFRA D842V-mutant gastrointestinal stromal tumour (NAVIGATOR): a multicentre, open-label, phase 1 trial

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Seven-day vonoprazan and low-dose amoxicillin dual therapy as first-line Helicobacter pylori treatment: a multicentre randomised trial in Japan

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Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial

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Atogepant for the Preventive Treatment of Migraine

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Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis

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Tofacitinib for Psoriatic Arthritis in Patients with an Inadequate Response to TNF Inhibitors

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Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4, double-blind, head-...

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The emerging safety profile of JAK inhibitors in rheumatic disease

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Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

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Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial

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Safety and efficacy of tofacitinib for up to 9.5 years in the treatment of rheumatoid arthritis: final results of a global, open-label, long-term extension study

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Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma

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Efficacy of glucocorticoids, conventional and targeted synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the 2016 update of the EULAR recommendations for the ma...

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Familial chilblain lupus due to a gain-of-function mutation in STING

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Overall Survival in Renal-Cell Carcinoma with Pazopanib versus Sunitinib

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Targeting renal cell carcinoma with a HIF-2 antagonist

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Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis

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