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44 results for Receptor,+IGF+Type+1+-+drug+effects

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ArticlesPeer ReviewedFull Text
Rationale for co-targeting IGF-1R and ALK in ALK fusion–positive lung cancer
Author / Creator:Lovly, Christine M ; McDonald, Nerina T ; Chen, Heidi ; Ortiz-Cuaran, Sandra ; Heukamp, Lukas C ; Yan, Yingjun ; Florin, Alexandra ; Ozretić, Luka ; Lim, Diana ; Wang, Lu ; Chen, Zhao ; Chen, Xi ; Lu, Pengcheng ; Paik, Paul K ; Shen, Ronglai ; Jin, Hailing ; Buettner, Reinhard ; Ansén, Sascha ; Perner, Sven ; Brockmann, Michael ; Bos, Marc ; Wolf, Jürgen ; Gardizi, Masyar ; Wright, Gavin M ; Solomon, Benjamin ; Russell, Prudence A ; Rogers, Toni-Maree ; Suehara, Yoshiyuki ; Red-Brewer, Monica ; Tieu, Rudy ; de Stanchina, Elisa ; Wang, Qingguo ; Zhao, Zhongming ; Johnson, David H ; Horn, Leora ; Wong, Kwok-Kin ; Thomas, Roman K ; Ladanyi, Marc ; Pao, William
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2014-09, Vol.20 (9), p.1027-1034
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Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type‐1 insulin‐like growth factor receptors in neuronal cells
Author / Creator:Zimbone, Stefania ; Monaco, Irene ; Gianì, Fiorenza ; Pandini, Giuseppe ; Copani, Agata G. ; Giuffrida, Maria Laura ; Rizzarelli, Enrico
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2018-02, Vol.17 (1), p.n/a
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Insulin Receptor Phosphorylation by Endogenous Insulin or the Insulin Analog AspB10 Promotes Mammary Tumor Growth Independent of the IGF-I Receptor
Author / Creator:GALLAGHER, Emily Jane ; ALIKHANI, Nyosha ; TOBIN-HESS, Aviva ; BLANK, Jeffrey ; BUFFIN, Nicholas J ; ZELENKO, Zara ; TENNAGELS, Norbert ; WERNER, Ulrich ; LEROITH, Derek
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2013-10, Vol.62 (10), p.3553-3560
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OSI-906 restores the sensitivity of ovarian clear cell carcinoma to cisplatin by targeting the IGF1R/AKT pathway
Author / Creator:Liu, Li ; Liang, Changyan ; Zhuo, Chenya ; Jiang, Huiyun ; Ye, Huixia ; Ruan, Tianyuan ; Song, Jiao ; Jiang, Senwei ; Zhang, Yu ; Li, Xiaomao
Publisher:New York: Springer US
Journal title:Medical oncology (Northwood, London, England), 2022-02, Vol.39 (2), p.26-26, Article 26
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Glucagon-Like Peptide-1 Protects β-Cells Against Apoptosis by Increasing the Activity of an Igf-2/Igf-1 Receptor Autocrine Loop
Author / Creator:CORNU, Marion ; YANG, Jiang-Yan ; JACCARD, Evrim ; POUSSIN, Carine ; WIDMANN, Christian ; THORENS, Bernard
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2009-08, Vol.58 (8), p.1816-1825
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Role of IGF-1 pathway in lung fibroblast activation
Author / Creator:Hung, Chi F ; Rohani, Maryam G ; Lee, Sung-Soon ; Chen, Peter ; Schnapp, Lynn M
Publisher:England: BioMed Central Ltd
Journal title:Respiratory research, 2013-10, Vol.14 (1), p.102-102, Article 102
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Targeting the IGF-Axis for Cancer Therapy: Development and Validation of an IGF-Trap as a Potential Drug
Author / Creator:Chen, Yinhsuan Michely ; Qi, Shu ; Perrino, Stephanie ; Hashimoto, Masakazu ; Brodt, Pnina
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2020-04, Vol.9 (5), p.1098
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Insulin X10 revisited: a super-mitogenic insulin analogue
Author / Creator:Hansen, B. F. ; Kurtzhals, P. ; Jensen, A. B. ; Dejgaard, A. ; Russell-Jones, D.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Diabetologia, 2011-09, Vol.54 (9), p.2226-2231
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Lung cancer: combating resistance through IGF-1R and ALK co-targeting
Author / Creator:Hutchinson, Lisa
Publisher:England: Nature Publishing Group
Journal title:Nature reviews. Clinical oncology, 2014-11, Vol.11 (11), p.622-622
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Targeting insulin-like growth factor pathways
Author / Creator:YEE, D
Publisher:Basingstoke: Nature Publishing Group
Journal title:British journal of cancer, 2006-02, Vol.94 (4), p.465-468
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The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathw...
Author / Creator:Vasilcanu, Daiana ; Girnita, Ada ; Girnita, Leonard ; Vasilcanu, Radu ; Axelson, Magnus ; Larsson, Olle
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2004-10, Vol.23 (47), p.7854-7862
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ArticlesPeer ReviewedFull Text
Lactoferrin inhibits apoptosis through insulin-like growth factor I in primary rat osteoblasts
Author / Creator:Hou, Jian-ming ; Chen, En-yu ; Wei, Shi-chao ; Lin, Fan ; Lin, Qing-ming ; Lan, Xu-hua ; Xue, Ying ; Wu, Man
Publisher:London: Nature Publishing Group UK
Journal title:Acta pharmacologica Sinica, 2014-04, Vol.35 (4), p.523-530
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Treatment With Insulin and Its Analogs in Pregnancies Complicated by Diabetes
Author / Creator:Jovanovic, Lois ; Pettitt, David J
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes care, 2007-07, Vol.30 (Supplement_2), p.S220-S224
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Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling
Author / Creator:Zhang, Donglei ; Brodt, Pnina
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2003-02, Vol.22 (7), p.974-982
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ArticlesPeer ReviewedFull Text
Conjugated Linoleic Acid Decreases MCF-7 Human Breast Cancer Cell Growth and Insulin-Like Growth Factor-1 Receptor Levels
Author / Creator:Amarù, Danielle L ; Field, Catherine J
Publisher:Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title:Lipids, 2009-05, Vol.44 (5), p.449-458
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Green Tea Induced Cellular Proliferation and the Expression of Transforming Growth Factor-β1 in the Jejunal Mucosa of Fasting Rats
Author / Creator:Mathew, Thazhumpal C. ; Abdeen, Suad M. ; Dashti, Hussain ; Asfar, Sami
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Medical principles and practice, 2017-01, Vol.26 (4), p.343-350
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ArticlesPeer ReviewedFull Text
Effect of type 1 insulin-like growth factor receptor targeted therapy on chemotherapy in human cancer and the mechanisms involved
Author / Creator:Hopkins, Alyse ; Crowe, Philip J ; Yang, Jia-Lin
Publisher:Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title:Journal of cancer research and clinical oncology, 2010-05, Vol.136 (5), p.639-650
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ArticlesPeer ReviewedFull Text
Insulin receptor signaling activated by penta-O-galloyl-α-d-glucopyranose induces p53 and apoptosis in cancer cells
Author / Creator:Cao, Yanyan ; Evans, Susan C. ; Soans, Eroica ; Malki, Ahmed ; Liu, Yi ; Liu, Yan ; Chen, Xiaozhuo
Publisher:Boston: Springer US
Journal title:Apoptosis (London), 2011-09, Vol.16 (9), p.902-913
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Growth factor receptors signaling in glioblastoma cells: therapeutic implications
Author / Creator:Carapancea, Mia ; Alexandru, Oana ; Fetea, Ani S. ; Dragutescu, Laura ; Castro, Juan ; Georgescu, Ada ; Popa-Wagner, A. ; Bäcklund, Magnus L. ; Lewensohn, Rolf ; Dricu, Anica
Publisher:Boston: Springer US
Journal title:Journal of neuro-oncology, 2009-04, Vol.92 (2), p.137-147
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Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines
Author / Creator:JACKSON, James G ; XIHONG ZHANG ; YONEDA, Toshiyuki ; YEE, Douglas
Publisher:Basingstoke: Nature Publishing
Journal title:Oncogene, 2001-11, Vol.20 (50), p.7318-7325
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Showing 1 to 20 of 44 results

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Rationale for co-targeting IGF-1R and ALK in ALK fusion–positive lung cancer

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Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type‐1 insulin‐like growth factor receptors in neuronal cells

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Insulin Receptor Phosphorylation by Endogenous Insulin or the Insulin Analog AspB10 Promotes Mammary Tumor Growth Independent of the IGF-I Receptor

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OSI-906 restores the sensitivity of ovarian clear cell carcinoma to cisplatin by targeting the IGF1R/AKT pathway

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Glucagon-Like Peptide-1 Protects β-Cells Against Apoptosis by Increasing the Activity of an Igf-2/Igf-1 Receptor Autocrine Loop

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Role of IGF-1 pathway in lung fibroblast activation

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Targeting the IGF-Axis for Cancer Therapy: Development and Validation of an IGF-Trap as a Potential Drug

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Insulin X10 revisited: a super-mitogenic insulin analogue

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Lung cancer: combating resistance through IGF-1R and ALK co-targeting

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Targeting insulin-like growth factor pathways

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The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathw...

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Lactoferrin inhibits apoptosis through insulin-like growth factor I in primary rat osteoblasts

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Treatment With Insulin and Its Analogs in Pregnancies Complicated by Diabetes

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Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling

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Conjugated Linoleic Acid Decreases MCF-7 Human Breast Cancer Cell Growth and Insulin-Like Growth Factor-1 Receptor Levels

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Green Tea Induced Cellular Proliferation and the Expression of Transforming Growth Factor-β1 in the Jejunal Mucosa of Fasting Rats

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Effect of type 1 insulin-like growth factor receptor targeted therapy on chemotherapy in human cancer and the mechanisms involved

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Insulin receptor signaling activated by penta-O-galloyl-α-d-glucopyranose induces p53 and apoptosis in cancer cells

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Growth factor receptors signaling in glioblastoma cells: therapeutic implications

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Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines

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