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190 results for Receptors,+Corticotropin-Releasing+Hormone+-+antagonists+

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Structure of class B GPCR corticotropin-releasing factor receptor 1
Author / Creator:Hollenstein, Kaspar ; Kean, James ; Bortolato, Andrea ; Cheng, Robert K. Y. ; Doré, Andrew S. ; Jazayeri, Ali ; Cooke, Robert M. ; Weir, Malcolm ; Marshall, Fiona H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-07, Vol.499 (7459), p.438-443
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The CRF1 Antagonist Verucerfont in Anxious Alcohol-Dependent Women: Translation of Neuroendocrine, But not of Anti-Craving Effects
Author / Creator:Schwandt, Melanie L ; Cortes, Carlos R ; Kwako, Laura E ; George, David T ; Momenan, Reza ; Sinha, Rajita ; Grigoriadis, Dimitri E ; Pich, Emilio Merlo ; Leggio, Lorenzo ; Heilig, Markus
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2016-11, Vol.41 (12), p.2818-2829
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Phase 3 Trial of Crinecerfont in Pediatric Congenital Adrenal Hyperplasia
Author / Creator:Sarafoglou, Kyriakie ; Kim, Mimi S. ; Lodish, Maya ; Felner, Eric I. ; Martinerie, Laetitia ; Nokoff, Natalie J. ; Clemente, María ; Fechner, Patricia Y. ; Vogiatzi, Maria G. ; Speiser, Phyllis W. ; Auchus, Richard J. ; Rosales, Gelliza B.G. ; Roberts, Eiry ; Jeha, George S. ; Farber, Robert H. ; Chan, Jean L.
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-08, Vol.391 (6), p.493-503
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Phase 3 Trial of Crinecerfont in Adult Congenital Adrenal Hyperplasia
Author / Creator:Auchus, Richard J. ; Hamidi, Oksana ; Pivonello, Rosario ; Bancos, Irina ; Russo, Gianni ; Witchel, Selma F. ; Isidori, Andrea M. ; Rodien, Patrice ; Srirangalingam, Umasuthan ; Kiefer, Florian W. ; Falhammar, Henrik ; Merke, Deborah P. ; Reisch, Nicole ; Sarafoglou, Kyriakie ; Cutler, Gordon B. ; Sturgeon, Julia ; Roberts, Eiry ; Lin, Vivian H. ; Chan, Jean L. ; Farber, Robert H.
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-08, Vol.391 (6), p.504-514
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Tildacerfont in Adults With Classic Congenital Adrenal Hyperplasia: Results from Two Phase 2 Studies
Author / Creator:Sarafoglou, Kyriakie ; Barnes, Chris N ; Huang, Michael ; Imel, Erik A ; Madu, Ivy-Joan ; Merke, Deborah P ; Moriarty, David ; Nakhle, Samer ; Newfield, Ron S ; Vogiatzi, Maria G ; Auchus, Richard J
Publisher:US: Oxford University Press
Journal title:The journal of clinical endocrinology and metabolism, 2021-11, Vol.106 (11), p.e4666-e4679
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Crinecerfont Lowers Elevated Hormone Markers in Adults With 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia
Author / Creator:Auchus, Richard J ; Sarafoglou, Kyriakie ; Fechner, Patricia Y ; Vogiatzi, Maria G ; Imel, Erik A ; Davis, Shanlee M ; Giri, Nagdeep ; Sturgeon, Julia ; Roberts, Eiry ; Chan, Jean L ; Farber, Robert H
Publisher:US: Oxford University Press
Journal title:The journal of clinical endocrinology and metabolism, 2022-03, Vol.107 (3), p.801-812
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The Corticotropin Releasing Hormone-1 (CRH1) Receptor Antagonist Pexacerfont in Alcohol Dependence: A Randomized Controlled Experimental Medicine Study
Author / Creator:Kwako, Laura E ; Spagnolo, Primavera A ; Schwandt, Melanie L ; Thorsell, Annika ; George, David T ; Momenan, Reza ; Rio, Daniel E ; Huestis, Marilyn ; Anizan, Sebastien ; Concheiro, Marta ; Sinha, Rajita ; Heilig, Markus
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2015-03, Vol.40 (5), p.1053-1063
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Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive
Author / Creator:Lemos, Julia C. ; Wanat, Matthew J. ; Smith, Jeffrey S. ; Reyes, Beverly A. S. ; Hollon, Nick G. ; Van Bockstaele, Elisabeth J. ; Chavkin, Charles ; Phillips, Paul E. M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-10, Vol.490 (7420), p.402-406
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Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1
Author / Creator:Refojo, Damian ; Schweizer, Martin ; Kuehne, Claudia ; Ehrenberg, Stefanie ; Thoeringer, Christoph ; Vogl, Annette M. ; Dedic, Nina ; Schumacher, Marion ; von Wolff, Gregor ; Avrabos, Charilaos ; Touma, Chadi ; Engblom, David ; Schütz, Günther ; Nave, Klaus-Armin ; Eder, Matthias ; Wotjak, Carsten T. ; Sillaber, Inge ; Holsboer, Florian ; Wurst, Wolfgang ; Deussing, Jan M.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2011-09, Vol.333 (6051), p.1903-1907
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Lost in Translation: CRF1 Receptor Antagonists and Addiction Treatment
Author / Creator:Shaham, Yavin ; de Wit, Harriet
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2016-11, Vol.41 (12), p.2795-2797
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Basic Science and Pathogenesis
Author / Creator:Ellisman, Maya Anne ; Sarsoza, Floyd ; Rissman, Robert A
Publisher:United States
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 Suppl 1, p.e092978
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The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling
Author / Creator:Bessa, J M ; Ferreira, D ; Melo, I ; Marques, F ; Cerqueira, J J ; Palha, J A ; Almeida, O F X ; Sousa, N
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2009-08, Vol.14 (8), p.764-773
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Dopamine and Stress System Modulation of Sex Differences in Decision Making
Author / Creator:Georgiou, Polymnia ; Zanos, Panos ; Bhat, Shambhu ; Tracy, J Kathleen ; Merchenthaler, Istvan J ; Mccarthy, Margaret M ; Gould, Todd D
Publisher:New York: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2018-01, Vol.43 (2), p.313
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Noradrenergic tone mediates marble burying behavior after chronic stress and ethanol
Author / Creator:den Hartog, Carolina R. ; Blandino, Katrina L. ; Nash, McKenzie L. ; Sjogren, Emily R. ; Grampetro, Michael A. ; Moorman, David E. ; Vazey, Elena M.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Psychopharmacology, 2020-10, Vol.237 (10), p.3021-3031
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Increased mesocorticolimbic dopamine during acute and repeated social defeat stress: modulation by corticotropin releasing factor receptors in the ventral tegmental area
Author / Creator:Holly, Elizabeth N. ; DeBold, Joseph F. ; Miczek, Klaus A.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Psychopharmacology, 2015-12, Vol.232 (24), p.4469-4479
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CRHR1 antagonist alleviates LPS-induced depression-like behaviour in mice
Author / Creator:Sun, Jie ; Qiu, Lili ; Zhang, Hui ; Zhou, Zhiqiang ; Ju, Lingsha ; Yang, Jiaojiao
Publisher:England: BioMed Central Ltd
Journal title:BMC psychiatry, 2023-01, Vol.23 (1), p.17-17, Article 17
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Predator odor increases avoidance and glutamatergic synaptic transmission in the prelimbic cortex via corticotropin-releasing factor receptor 1 signaling
Author / Creator:Hwa, Lara S ; Neira, Sofia ; Pina, Melanie M ; Pati, Dipanwita ; Calloway, Rachel ; Kash, Thomas L
Publisher:New York: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2019-03, Vol.44 (4), p.766-775
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Blocking CRH receptors in adults mitigates age-related memory impairments provoked by early-life adversity
Author / Creator:Short, Annabel K ; Maras, Pamela M ; Pham, Aidan L ; Ivy, Autumn S ; Baram Tallie Z
Publisher:New York: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2020-02, Vol.45 (3), p.515-523
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Design, Synthesis, and Biological Evaluations of Novel Thiazolo[4,5-d]pyrimidine Corticotropin Releasing Factor (CRF) Receptor Antagonists as Potential Treatments for Stress Related Disorders and Cong...
Author / Creator:Islam, Md Rabiul ; Markatos, Christos ; Pirmettis, Ioannis ; Papadopoulos, Minas ; Karageorgos, Vlasios ; Liapakis, George ; Fahmy, Hesham
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-08, Vol.29 (15), p.3647
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Stress-enhanced ethanol drinking does not increase sensitivity to the effects of a CRF-R1 antagonist on ethanol intake in male and female mice
Author / Creator:Nipper, Michelle A ; Helms, Melinda L ; Finn, Deborah A ; Ryabinin, Andrey E
Publisher:United States: Elsevier Inc
Journal title:Alcohol (Fayetteville, N.Y.), 2024-11, Vol.120, p.73-83
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Showing 1 to 20 of 190 results

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Structure of class B GPCR corticotropin-releasing factor receptor 1

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The CRF1 Antagonist Verucerfont in Anxious Alcohol-Dependent Women: Translation of Neuroendocrine, But not of Anti-Craving Effects

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Phase 3 Trial of Crinecerfont in Pediatric Congenital Adrenal Hyperplasia

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Phase 3 Trial of Crinecerfont in Adult Congenital Adrenal Hyperplasia

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Tildacerfont in Adults With Classic Congenital Adrenal Hyperplasia: Results from Two Phase 2 Studies

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Crinecerfont Lowers Elevated Hormone Markers in Adults With 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia

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The Corticotropin Releasing Hormone-1 (CRH1) Receptor Antagonist Pexacerfont in Alcohol Dependence: A Randomized Controlled Experimental Medicine Study

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Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive

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Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1

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Lost in Translation: CRF1 Receptor Antagonists and Addiction Treatment

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Basic Science and Pathogenesis

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The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling

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Dopamine and Stress System Modulation of Sex Differences in Decision Making

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Noradrenergic tone mediates marble burying behavior after chronic stress and ethanol

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Increased mesocorticolimbic dopamine during acute and repeated social defeat stress: modulation by corticotropin releasing factor receptors in the ventral tegmental area

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CRHR1 antagonist alleviates LPS-induced depression-like behaviour in mice

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Predator odor increases avoidance and glutamatergic synaptic transmission in the prelimbic cortex via corticotropin-releasing factor receptor 1 signaling

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Blocking CRH receptors in adults mitigates age-related memory impairments provoked by early-life adversity

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Design, Synthesis, and Biological Evaluations of Novel Thiazolo[4,5-d]pyrimidine Corticotropin Releasing Factor (CRF) Receptor Antagonists as Potential Treatments for Stress Related Disorders and Cong...

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Stress-enhanced ethanol drinking does not increase sensitivity to the effects of a CRF-R1 antagonist on ethanol intake in male and female mice

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