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1,870 results for Receptors,+Estrogen+-+genetics

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ArticlesPeer ReviewedFull Text
Gasdermin E suppresses tumour growth by activating anti-tumour immunity
Author / Creator:Zhang, Zhibin ; Zhang, Ying ; Xia, Shiyu ; Kong, Qing ; Li, Shunying ; Liu, Xing ; Junqueira, Caroline ; Meza-Sosa, Karla F. ; Mok, Temy Mo Yin ; Ansara, James ; Sengupta, Satyaki ; Yao, Yandan ; Wu, Hao ; Lieberman, Judy
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-03, Vol.579 (7799), p.415-420
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The role of pyroptosis in cancer: pro-cancer or pro-“host”?
Author / Creator:Xia, Xiaojing ; Wang, Xin ; Cheng, Zhe ; Qin, Wanhai ; Lei, Liancheng ; Jiang, Jinqing ; Hu, Jianhe
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-09, Vol.10 (9), p.650-13, Article 650
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Palbociclib with adjuvant endocrine therapy in early breast cancer (PALLAS): interim analysis of a multicentre, open-label, randomised, phase 3 study
Author / Creator:Mayer, Erica L, MD ; Dueck, Amylou C, PhD ; Martin, Miguel, Prof ; Rubovszky, Gabor, PhD ; Burstein, Harold J, Prof ; Bellet-Ezquerra, Meritxell, MD ; Miller, Kathy D, MD ; Zdenkowski, Nicholas, PhD ; Winer, Eric P, Prof ; Pfeiler, Georg, MD ; Goetz, Matthew, Prof ; Ruiz-Borrego, Manuel, MD ; Anderson, Daniel, MD ; Nowecki, Zbigniew, MD ; Loibl, Sibylle, Prof ; Moulder, Stacy, Prof ; Ring, Alistair, FRCP ; Fitzal, Florian, MD ; Traina, Tiffany, MD ; Chan, Arlene, Prof ; Rugo, Hope S, Prof ; Lemieux, Julie, MD ; Henao, Fernando, MD ; Lyss, Alan, MD ; Antolin Novoa, Silvia, MD ; Wolff, Antonio C, Prof ; Vetter, Marcus, MD ; Egle, Daniel, MD ; Morris, Patrick G, Prof ; Mamounas, Eleftherios P, Prof ; Gil-Gil, Miguel J, MD ; Prat, Aleix, Prof ; Fohler, Hannes, MVM ; Metzger Filho, Otto, MD ; Schwarz, Magdalena, MSc ; DuFrane, Carter, BA ; Fumagalli, Debora, MD ; Theall, Kathy Puyana, MD ; Lu, Dongrui Ray, MS ; Bartlett, Cynthia Huang, MD ; Koehler, Maria, MD ; Fesl, Christian, PhD ; DeMichele, Angela, Prof ; Gnant, Michael, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2021-02, Vol.22 (2), p.212-222
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Alpelisib plus fulvestrant in PIK3CA-mutated, hormone receptor-positive advanced breast cancer after a CDK4/6 inhibitor (BYLieve): one cohort of a phase 2, multicentre, open-label, non-comparative stu...
Author / Creator:Rugo, Hope S ; Lerebours, Florence ; Ciruelos, Eva ; Drullinsky, Pamela ; Ruiz-Borrego, Manuel ; Neven, Patrick ; Park, Yeon Hee ; Prat, Aleix ; Bachelot, Thomas ; Juric, Dejan ; Turner, Nicholas ; Sophos, Nickolas ; Zarate, Juan Pablo ; Arce, Christina ; Shen, Yu-Ming ; Turner, Stuart ; Kanakamedala, Hemanth ; Hsu, Wei-Chun ; Chia, Stephen
Publisher:England: Elsevier Limited
Journal title:The lancet oncology, 2021-04, Vol.22 (4), p.489-498
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Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
Author / Creator:Rogers, Corey ; Erkes, Dan A. ; Nardone, Alexandria ; Aplin, Andrew E. ; Fernandes-Alnemri, Teresa ; Alnemri, Emad S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-04, Vol.10 (1), p.1689-1689, Article 1689
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HER2-low breast cancers: incidence, HER2 staining patterns, clinicopathologic features, MammaPrint and BluePrint genomic profiles
Author / Creator:Zhang, Huina ; Katerji, Hani ; Turner, Bradley M. ; Audeh, William ; Hicks, David G.
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2022-08, Vol.35 (8), p.1075-1082
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Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial
Author / Creator:Turner, Nicholas C, Prof ; Kingston, Belinda, MB ; Kilburn, Lucy S, MSc ; Kernaghan, Sarah, BSc ; Wardley, Andrew M, Prof ; Macpherson, Iain R, MD ; Baird, Richard D, MD ; Roylance, Rebecca, MD ; Stephens, Peter, PhD ; Oikonomidou, Olga, MD ; Braybrooke, Jeremy P, FRCP ; Tuthill, Mark, MRCP ; Abraham, Jacinta, BMBS ; Winter, Matthew C, MD ; Bye, Hannah, PhD ; Hubank, Michael, PhD ; Gevensleben, Heidrun, MD ; Cutts, Ros, PhD ; Snowdon, Claire, MSc ; Rea, Daniel, Prof ; Cameron, David, Prof ; Shaaban, Abeer, PhD ; Randle, Katrina, MSc ; Martin, Sue, BSc ; Wilkinson, Katie, BSc ; Moretti, Laura, MSc ; Bliss, Judith M, Prof ; Ring, Alistair, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-10, Vol.21 (10), p.1296-1308
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ESR1 mutation as an emerging clinical biomarker in metastatic hormone receptor-positive breast cancer
Author / Creator:Brett, Jamie O. ; Spring, Laura M. ; Bardia, Aditya ; Wander, Seth A.
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2021-08, Vol.23 (1), p.85-15, Article 85
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Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups
Author / Creator:Rueda, Oscar M. ; Sammut, Stephen-John ; Seoane, Jose A. ; Chin, Suet-Feung ; Caswell-Jin, Jennifer L. ; Callari, Maurizio ; Batra, Rajbir ; Pereira, Bernard ; Bruna, Alejandra ; Ali, H. Raza ; Provenzano, Elena ; Liu, Bin ; Parisien, Michelle ; Gillett, Cheryl ; McKinney, Steven ; Green, Andrew R. ; Murphy, Leigh ; Purushotham, Arnie ; Ellis, Ian O. ; Pharoah, Paul D. ; Rueda, Cristina ; Aparicio, Samuel ; Caldas, Carlos ; Curtis, Christina
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-03, Vol.567 (7748), p.399-404
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ArticlesPeer ReviewedFull Text
The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles
Author / Creator:Leidal, Andrew M. ; Huang, Hector H. ; Marsh, Timothy ; Solvik, Tina ; Zhang, Dachuan ; Ye, Jordan ; Kai, FuiBoon ; Goldsmith, Juliet ; Liu, Jennifer Y. ; Huang, Yu-Hsin ; Monkkonen, Teresa ; Vlahakis, Ariadne ; Huang, Eric J. ; Goodarzi, Hani ; Yu, Li ; Wiita, Arun P. ; Debnath, Jayanta
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2020-02, Vol.22 (2), p.187-199
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ArticlesPeer ReviewedFull Text
Catalytic in vivo protein knockdown by small-molecule PROTACs
Author / Creator:Bondeson, Daniel P ; Mares, Alina ; Smith, Ian E D ; Ko, Eunhwa ; Campos, Sebastien ; Miah, Afjal H ; Mulholland, Katie E ; Routly, Natasha ; Buckley, Dennis L ; Gustafson, Jeffrey L ; Zinn, Nico ; Grandi, Paola ; Shimamura, Satoko ; Bergamini, Giovanna ; Faelth-Savitski, Maria ; Bantscheff, Marcus ; Cox, Carly ; Gordon, Deborah A ; Willard, Ryan R ; Flanagan, John J ; Casillas, Linda N ; Votta, Bartholomew J ; den Besten, Willem ; Famm, Kristoffer ; Kruidenier, Laurens ; Carter, Paul S ; Harling, John D ; Churcher, Ian ; Crews, Craig M
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2015-08, Vol.11 (8), p.611-617
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ArticlesPeer ReviewedFull Text
The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase
Author / Creator:Cox, Thomas R ; Rumney, Robin M H ; Schoof, Erwin M ; Perryman, Lara ; Høye, Anette M ; Agrawal, Ankita ; Bird, Demelza ; Latif, Norain Ab ; Forrest, Hamish ; Evans, Holly R ; Huggins, Iain D ; Lang, Georgina ; Linding, Rune ; Gartland, Alison ; Erler, Janine T
Publisher:England: Nature Publishing Group
Journal title:Nature (London), 2015-06, Vol.522 (7554), p.106-110
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ArticlesPeer ReviewedFull Text
Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer
Author / Creator:O’Leary, Ben ; Hrebien, Sarah ; Morden, James P. ; Beaney, Matthew ; Fribbens, Charlotte ; Huang, Xin ; Liu, Yuan ; Bartlett, Cynthia Huang ; Koehler, Maria ; Cristofanilli, Massimo ; Garcia-Murillas, Isaac ; Bliss, Judith M. ; Turner, Nicholas C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-03, Vol.9 (1), p.896-10, Article 896
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Proteomic profiling reveals that ESR1 mutations enhance cyclin-dependent kinase signaling
Author / Creator:De Marchi, Tommaso ; Lai, Chun-Fui ; Simmons, Georgia M. ; Goldsbrough, Isabella ; Harrod, Alison ; Lam, Thai ; Buluwela, Lakjaya ; Kjellström, Sven ; Brueffer, Christian ; Saal, Lao H. ; Malmström, Johan ; Ali, Simak ; Niméus, Emma
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-03, Vol.14 (1), p.6873-6873, Article 6873
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Cutoff Finder: A Comprehensive and Straightforward Web Application Enabling Rapid Biomarker Cutoff Optimization
Author / Creator:Budczies, Jan ; Klauschen, Frederick ; Sinn, Bruno V. ; Győrffy, Balázs ; Schmitt, Wolfgang D. ; Darb-Esfahani, Silvia ; Denkert, Carsten
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-12, Vol.7 (12), p.e51862-e51862
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The Role of the Estrogen Pathway in the Tumor Microenvironment
Author / Creator:Rothenberger, Natalie ; Somasundaram, Ashwin ; Stabile, Laura
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-02, Vol.19 (2), p.611
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Estrogen Receptors and Endometriosis
Author / Creator:Chantalat, Elodie ; Valera, Marie-Cécile ; Vaysse, Charlotte ; Noirrit, Emmanuelle ; Rusidze, Mariam ; Weyl, Ariane ; Vergriete, Kelig ; Buscail, Etienne ; Lluel, Philippe ; Fontaine, Coralie ; Arnal, Jean-François ; Lenfant, Françoise
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-04, Vol.21 (8), p.2815
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Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor–directed therapies
Author / Creator:Nayar, Utthara ; Cohen, Ofir ; Kapstad, Christian ; Cuoco, Michael S. ; Waks, Adrienne G. ; Wander, Seth A. ; Painter, Corrie ; Freeman, Samuel ; Persky, Nicole S. ; Marini, Lori ; Helvie, Karla ; Oliver, Nelly ; Rozenblatt-Rosen, Orit ; Ma, Cynthia X. ; Regev, Aviv ; Winer, Eric P. ; Lin, Nancy U. ; Wagle, Nikhil
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2019-02, Vol.51 (2), p.207-216
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Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
Author / Creator:Yu, Junhui ; Li, Shan ; Qi, Jie ; Chen, Zilu ; Wu, Yunhua ; Guo, Jing ; Wang, Kai ; Sun, Xuejun ; Zheng, Jianbao
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-02, Vol.10 (3), p.193-193, Article 193
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Estrogen receptor positive breast cancers have patient specific hormone sensitivities and rely on progesterone receptor
Author / Creator:Scabia, Valentina ; Ayyanan, Ayyakkannu ; De Martino, Fabio ; Agnoletto, Andrea ; Battista, Laura ; Laszlo, Csaba ; Treboux, Assia ; Zaman, Khalil ; Stravodimou, Athina ; Jallut, Didier ; Fiche, Maryse ; Bucher, Philip ; Ambrosini, Giovanna ; Sflomos, George ; Brisken, Cathrin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-06, Vol.13 (1), p.3127-3127, Article 3127
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Gasdermin E suppresses tumour growth by activating anti-tumour immunity

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The role of pyroptosis in cancer: pro-cancer or pro-“host”?

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Palbociclib with adjuvant endocrine therapy in early breast cancer (PALLAS): interim analysis of a multicentre, open-label, randomised, phase 3 study

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Alpelisib plus fulvestrant in PIK3CA-mutated, hormone receptor-positive advanced breast cancer after a CDK4/6 inhibitor (BYLieve): one cohort of a phase 2, multicentre, open-label, non-comparative stu...

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Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

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HER2-low breast cancers: incidence, HER2 staining patterns, clinicopathologic features, MammaPrint and BluePrint genomic profiles

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Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial

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ESR1 mutation as an emerging clinical biomarker in metastatic hormone receptor-positive breast cancer

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Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups

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The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles

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Catalytic in vivo protein knockdown by small-molecule PROTACs

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The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

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Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer

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Proteomic profiling reveals that ESR1 mutations enhance cyclin-dependent kinase signaling

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Cutoff Finder: A Comprehensive and Straightforward Web Application Enabling Rapid Biomarker Cutoff Optimization

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The Role of the Estrogen Pathway in the Tumor Microenvironment

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Estrogen Receptors and Endometriosis

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Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor–directed therapies

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Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells

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Estrogen receptor positive breast cancers have patient specific hormone sensitivities and rely on progesterone receptor

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