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ArticlesPeer ReviewedFull Text
Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
Author / Creator:Vande Walle, Lieselotte ; Van Opdenbosch, Nina ; Jacques, Peggy ; Fossoul, Amelie ; Verheugen, Eveline ; Vogel, Peter ; Beyaert, Rudi ; Elewaut, Dirk ; Kanneganti, Thirumala-Devi ; van Loo, Geert ; Lamkanfi, Mohamed
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-08, Vol.512 (7512), p.69-73
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IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
Author / Creator:Nold-Petry, Claudia A ; Lo, Camden Y ; Rudloff, Ina ; Elgass, Kirstin D ; Li, Suzhao ; Gantier, Michael P ; Lotz-Havla, Amelie S ; Gersting, Søren W ; Cho, Steven X ; Lao, Jason C ; Ellisdon, Andrew M ; Rotter, Björn ; Azam, Tania ; Mangan, Niamh E ; Rossello, Fernando J ; Whisstock, James C ; Bufler, Philip ; Garlanda, Cecilia ; Mantovani, Alberto ; Dinarello, Charles A ; Nold, Marcel F
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2015-04, Vol.16 (4), p.354-365
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The composition and signaling of the IL-35 receptor are unconventional
Author / Creator:Collison, Lauren W ; Delgoffe, Greg M ; Guy, Clifford S ; Vignali, Kate M ; Chaturvedi, Vandana ; Fairweather, DeLisa ; Satoskar, Abhay R ; Garcia, K Christopher ; Hunter, Christopher A ; Drake, Charles G ; Murray, Peter J ; Vignali, Dario A A
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2012-03, Vol.13 (3), p.290-299
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Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies
Author / Creator:Brydges, Susannah D ; Broderick, Lori ; McGeough, Matthew D ; Pena, Carla A ; Mueller, James L ; Hoffman, Hal M
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-11, Vol.123 (11), p.4695-4705
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Gout-associated uric acid crystals activate the NALP3 inflammasome
Author / Creator:Martinon, Fabio ; Pétrilli, Virginie ; Mayor, Annick ; Tardivel, Aubry ; Tschopp, Jürg
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2006-03, Vol.440 (7081), p.237-241
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Myeloid cell TBK1 restricts inflammatory responses
Author / Creator:Gao, Tianxiao ; Liu, Ting ; Ko, Chun-Jung ; Zhang, Lingyun ; Joo, Donghyun ; Xie, Xiaoping ; Zhu, Lele ; Li, Yanchuan ; Cheng, Xuhong ; Sun, Shao-Cong
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-01, Vol.119 (4), p.1-11
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Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression
Author / Creator:Goshen, I ; Kreisel, T ; Ben-Menachem-Zidon, O ; Licht, T ; Weidenfeld, J ; Ben-Hur, T ; Yirmiya, R
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2008-07, Vol.13 (7), p.717-728
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IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation
Author / Creator:Russell, S E ; Horan, R M ; Stefanska, A M ; Carey, A ; Leon, G ; Aguilera, M ; Statovci, D ; Moran, T ; Fallon, P G ; Shanahan, F ; Brint, E K ; Melgar, S ; Hussey, S ; Walsh, P T
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2016-09, Vol.9 (5), p.1193-1204
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Interleukin-1β overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents
Author / Creator:Gui, Wen-Shan ; Wei, Xiao ; Mai, Chun-Lin ; Murugan, Madhuvika ; Wu, Long-Jun ; Xin, Wen-Jun ; Zhou, Li-Jun ; Liu, Xian-Guo
Publisher:Los Angeles, CA: SAGE Publications
Journal title:Molecular pain, 2016, Vol.12
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MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
Author / Creator:Chen, Chun-Jen ; Shi, Yan ; Hearn, Arron ; Fitzgerald, Kate ; Golenbock, Douglas ; Reed, George ; Akira, Shizuo ; Rock, Kenneth L
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2006-08, Vol.116 (8), p.2262-2271
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ArticlesPeer ReviewedFull Text
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis
Author / Creator:Drexler, Stefan K ; Bonsignore, Luca ; Masin, Mark ; Tardivel, Aubry ; Jackstadt, Rene ; Hermeking, Heiko ; Schneider, Pascal ; Gross, Olaf ; Tschopp, Jurg ; Yazdi, Amir S
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (45), p.18384-18389
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ArticlesPeer ReviewedFull Text
Interleukin-1 Receptor 1 Deletion in Focal and Diffuse Experimental Traumatic Brain Injury in Mice
Author / Creator:Chung, Joon Yong ; Krapp, Nicolas ; Wu, Limin ; Lule, Sevda ; McAllister, Lauren M ; Edmiston, 3rd, William J ; Martin, Samantha ; Levy, Emily ; Songtachalert, Tanya ; Sherwood, John S ; Buckley, Erin M ; Sanders, Bharat ; Izzy, Saef ; Hickman, Suzanne ; Guo, Shuzhen ; Lok, Josephine ; El Khoury, Joseph ; Lo, Eng H ; Kaplan, David ; Whalen, Michael J
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Journal of neurotrauma, 2019-01, Vol.36 (2), p.370-379
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ArticlesPeer ReviewedFull Text
Immune response against Chlamydia trachomatis via toll-like receptors is negatively regulated by SIGIRR
Author / Creator:Al-Kuhlani, Mufadhal ; Lambert, Graham ; Pal, Sukumar ; de la Maza, Luis ; Ojcius, David M
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-03, Vol.15 (3), p.e0230718-e0230718
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Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice
Author / Creator:SUTHERLAND, Andrew P. R ; VAN BELLE, Tom ; WURSTER, Andrea L ; SUTO, Akira ; MICHAUD, Monia ; ZHANG, Dorothy ; GRUSBY, Michael J ; VON HERRATH, Matthias
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2009-05, Vol.58 (5), p.1144-1155
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Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects
Author / Creator:Tomasoni, Romana ; Morini, Raffaella ; Lopez-Atalaya, Jose P ; Corradini, Irene ; Canzi, Alice ; Rasile, Marco ; Mantovani, Cristina ; Pozzi, Davide ; Garlanda, Cecilia ; Mantovani, Alberto ; Menna, Elisabetta ; Barco, Angel ; Matteoli, Michela
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2017-03, Vol.6
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ArticlesPeer ReviewedFull Text
The ABP Dendrimer, a Drug-Candidate against Inflammatory Diseases That Triggers the Activation of Interleukin-10 Producing Immune Cells
Author / Creator:Fruchon, Séverine ; Poupot, Rémy
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-05, Vol.23 (6), p.1272
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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
Author / Creator:Horng, Tiffany ; Barton, Gregory M. ; Flavell, Richard A. ; Medzhitov, Ruslan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2002-11, Vol.420 (6913), p.329-333
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Interleukin-36γ is expressed by neutrophils and can activate microglia, but has no role in experimental autoimmune encephalomyelitis
Author / Creator:Bozoyan, Lusine ; Dumas, Aline ; Patenaude, Alexandre ; Vallières, Luc
Publisher:England: BioMed Central
Journal title:Journal of neuroinflammation, 2015-09, Vol.12 (1), p.173-173, Article 173
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ArticlesPeer ReviewedFull Text
Intestinal Inflammation in Mice Deficient in Tir8, an Inhibitory Member of the IL-1 Receptor Family
Author / Creator:Garlanda, Cecilia ; Riva, Federica ; Polentarutti, Nadia ; Buracchi, Chiara ; Sironi, Marina ; De Bortoli, Maida ; Muzio, Marta ; Bergottini, Raffaella ; Scanziani, Eugenio ; Vecchi, Annunciata ; Hirsch, Emilio ; Mantovani, Alberto ; Dinarello, Charles A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (10), p.3522-3526
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ArticlesPeer ReviewedFull Text
Synthesis, characterization, and bioactivity of carboxylic acid-functionalized titanium dioxide nanobelts
Author / Creator:Hamilton, Raymond F ; Wu, Nianqiang ; Xiang, Chengcheng ; Li, Ming ; Yang, Feng ; Wolfarth, Michael ; Porter, Dale W ; Holian, Andrij
Publisher:England: BioMed Central Ltd
Journal title:Particle and fibre toxicology, 2014-09, Vol.11 (1), p.43-43, Article 43
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Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

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IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction

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The composition and signaling of the IL-35 receptor are unconventional

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Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies

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Gout-associated uric acid crystals activate the NALP3 inflammasome

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Myeloid cell TBK1 restricts inflammatory responses

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Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression

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IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation

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Interleukin-1β overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents

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MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals

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Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis

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Interleukin-1 Receptor 1 Deletion in Focal and Diffuse Experimental Traumatic Brain Injury in Mice

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Immune response against Chlamydia trachomatis via toll-like receptors is negatively regulated by SIGIRR

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Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice

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Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects

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The ABP Dendrimer, a Drug-Candidate against Inflammatory Diseases That Triggers the Activation of Interleukin-10 Producing Immune Cells

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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

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Interleukin-36γ is expressed by neutrophils and can activate microglia, but has no role in experimental autoimmune encephalomyelitis

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Intestinal Inflammation in Mice Deficient in Tir8, an Inhibitory Member of the IL-1 Receptor Family

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Synthesis, characterization, and bioactivity of carboxylic acid-functionalized titanium dioxide nanobelts

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