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ArticlesPeer ReviewedFull Text
Hypoxia induces rapid changes to histone methylation and reprograms chromatin
Author / Creator:Batie, Michael ; Frost, Julianty ; Frost, Mark ; Wilson, James W. ; Schofield, Pieta ; Rocha, Sonia
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2019-03, Vol.363 (6432), p.1222-1226
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Pediatric non–Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes
Author / Creator:de Rooij, Jasmijn D E ; Branstetter, Cristyn ; Ma, Jing ; Li, Yongjin ; Walsh, Michael P ; Cheng, Jinjun ; Obulkasim, Askar ; Dang, Jinjun ; Easton, John ; Verboon, Lonneke J ; Mulder, Heather L ; Zimmermann, Martin ; Koss, Cary ; Gupta, Pankaj ; Edmonson, Michael ; Rusch, Michael ; Lim, Joshua Yew Suang ; Reinhardt, Katarina ; Pigazzi, Martina ; Song, Guangchun ; Yeoh, Allen Eng Juh ; Shih, Lee-Yung ; Liang, Der-Cherng ; Halene, Stephanie ; Krause, Diane S ; Zhang, Jinghui ; Downing, James R ; Locatelli, Franco ; Reinhardt, Dirk ; van den Heuvel-Eibrink, Marry M ; Zwaan, C Michel ; Fornerod, Maarten ; Gruber, Tanja A
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2017-03, Vol.49 (3), p.451-456
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Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
Author / Creator:Greer, Eric L. ; Maures, Travis J. ; Ucar, Duygu ; Hauswirth, Anna G. ; Mancini, Elena ; Lim, Jana P. ; Benayoun, Bérénice A. ; Shi, Yang ; Brunet, Anne
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-11, Vol.479 (7373), p.365-371
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Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans
Author / Creator:Greer, Eric L. ; Maures, Travis J. ; Hauswirth, Anna G. ; Green, Erin M. ; Leeman, Dena S. ; Maro, Géraldine S. ; Han, Shuo ; Banko, Max R. ; Gozani, Or ; Brunet, Anne
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-07, Vol.466 (7304), p.383-387
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Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling
Author / Creator:Longbotham, James E. ; Chio, Cynthia M. ; Dharmarajan, Venkatasubramanian ; Trnka, Michael J. ; Torres, Idelisse Ortiz ; Goswami, Devrishi ; Ruiz, Karen ; Burlingame, Alma L. ; Griffin, Patrick R. ; Fujimori, Danica Galonić
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-01, Vol.10 (1), p.94-94, Article 94
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KDM5A mutations identified in autism spectrum disorder using forward genetics
Author / Creator:El Hayek, Lauretta ; Tuncay, Islam Oguz ; Nijem, Nadine ; Russell, Jamie ; Ludwig, Sara ; Kaur, Kiran ; Li, Xiaohong ; Anderton, Priscilla ; Tang, Miao ; Gerard, Amanda ; Heinze, Anja ; Zacher, Pia ; Alsaif, Hessa S ; Rad, Aboulfazl ; Hassanpour, Kazem ; Abbaszadegan, Mohammad Reza ; Washington, Camerun ; DuPont, Barbara R ; Louie, Raymond J ; Couse, Madeline ; Faden, Maha ; Rogers, R Curtis ; Abou Jamra, Rami ; Elias, Ellen R ; Maroofian, Reza ; Houlden, Henry ; Lehman, Anna ; Beutler, Bruce ; Chahrour, Maria H
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-12, Vol.9
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NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern
Author / Creator:de Rooij, J D E ; Hollink, I H I M ; Arentsen-Peters, S T C J M ; van Galen, J F ; Berna Beverloo, H ; Baruchel, A ; Trka, J ; Reinhardt, D ; Sonneveld, E ; Zimmermann, M ; Alonzo, T A ; Pieters, R ; Meshinchi, S ; van den Heuvel-Eibrink, M M ; Zwaan, C Michel
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2013-12, Vol.27 (12), p.2280-2288
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Mechanism of histone demethylase KDM5A in osteoporotic fracture healing through epigenetic regulation of the miR-495/SKP2/Runx2 axis
Author / Creator:Li, Zhuoran ; Zhang, Junyan ; Xu, Tingting ; Hao, Zhiying ; Li, Yadong
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2025-02, Vol.31 (1), p.65-17, Article 65
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AUP1 transcriptionally activated by KDM5B reprograms lipid metabolism to promote the malignant progression of cervical cancer
Author / Creator:Zhu, Yingping ; Yang, Wenjuan ; Wang, Xinyan ; Chen, Mengmeng
Publisher:Athens: Spandidos Publications
Journal title:International journal of oncology, 2024-11, Vol.65 (5), p.1, Article 107
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The KDM5A/HOXA5 axis regulates osteosarcoma progression via activating the Wnt/β-catenin pathway
Author / Creator:Luo, Yi ; He, Youzhi ; Xu, Yuxia ; Wang, Yongfu ; Yang, Li
Publisher:England: BioMed Central
Journal title:European journal of medical research, 2025-04, Vol.30 (1), p.284-15, Article 284
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Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion
Author / Creator:Zhang, Yi ; Guo, Yiran ; Gough, Sheryl M. ; Zhang, Jinyong ; Vann, Kendra R. ; Li, Kuai ; Cai, Ling ; Shi, Xiaobing ; Aplan, Peter D. ; Wang, Gang Greg ; Kutateladze, Tatiana G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-07, Vol.11 (1), p.3339-10, Article 3339
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Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis
Author / Creator:Yoo, Jung ; Kim, Go Woon ; Jeon, Yu Hyun ; Kim, Ji Yoon ; Lee, Sang Wu ; Kwon, So Hee
Publisher:London: Nature Publishing Group UK
Journal title:Experimental & molecular medicine, 2022-12, Vol.54 (12), p.2107-2117
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Histone Demethylase Retinoblastoma Binding Protein 2 is Overexpressed in Hepatocellular Carcinoma and Negatively Regulated by hsa-miR-212
Author / Creator:Liang, Xiuming ; Zeng, Jiping ; Wang, Lixiang ; Fang, Ming ; Wang, Qing ; Zhao, Min ; Xu, Xia ; Liu, Zhifang ; Li, Wenjuan ; Liu, Shili ; Yu, Han ; Jia, Jihui ; Chen, Chunyan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-07, Vol.8 (7), p.e69784
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Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A
Author / Creator:Chaturvedi, Chandra-Prakash ; Somasundaram, Brinda ; Singh, Kulwant ; Carpenedo, Richard L ; Stanford, William L ; Dilworth, F. Jeffrey ; Brand, Marjorie
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (46), p.18845-18850
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Gene mutation analysis using next‐generation sequencing and its clinical significance in patients with myeloid neoplasm: A multi‐center study from China
Author / Creator:Li, Junnan ; Pei, Li ; Liang, Simin ; Xu, Shuangnian ; Wang, Yi ; Wang, Xiao ; Liao, Yi ; Zhan, Qian ; Cheng, Wei ; Yang, Zesong ; Tang, Xiaoqiong ; Zhang, Hongbin ; Xiao, Qing ; Chen, Jianbin ; Liu, Lin ; Wang, Li
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2023-04, Vol.12 (8), p.9332-9350
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KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance
Author / Creator:Gaillard, Solenne ; Charasson, Virginie ; Ribeyre, Cyril ; Salifou, Kader ; Pillaire, Marie-Jeanne ; Hoffmann, Jean-Sebastien ; Constantinou, Angelos ; Trouche, Didier ; Vandromme, Marie
Publisher:England: Royal Society
Journal title:Biology open, 2021-05, Vol.10 (5)
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Variable Phenotypes of Epilepsy, Intellectual Disability, and Schizophrenia Caused by 12p13.33–p13.32 Terminal Microdeletion in a Korean Family: A Case Report and Literature Review
Author / Creator:Han, Ji Yoon ; Park, Joonhong
Publisher:Switzerland: MDPI AG
Journal title:Genes, 2021-06, Vol.12 (7), p.1001
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Drug-Tolerant Cancer Cells Show Reduced Tumor-Initiating Capacity: Depletion of CD44+ Cells and Evidence for Epigenetic Mechanisms
Author / Creator:Yan, Hong ; Chen, Xin ; Zhang, Qiuping ; Qin, Jichao ; Li, Hangwen ; Liu, Can ; Calhoun-Davis, Tammy ; Coletta, Luis Della ; Klostergaard, Jim ; Fokt, Izabela ; Skora, Stanislaw ; Priebe, Waldemar ; Bi, Yongyi ; Tang, Dean G.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-09, Vol.6 (9), p.e24397
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JARID1A, JMY, and PTGER4 Polymorphisms Are Related to Ankylosing Spondylitis in Chinese Han Patients: A Case-Control Study
Author / Creator:Chai, Wei ; Lian, Zijian ; Chen, Chao ; Liu, Jingyi ; Shi, Lewis L. ; Wang, Yan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-09, Vol.8 (9), p.e74794-e74794
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Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4
Author / Creator:Seiler, Doris M ; Rouquette, Jacques ; Schmid, Volker J ; Strickfaden, Hilmar ; Ottmann, Christian ; Drexler, Guido A ; Mazurek, Belinda ; Greubel, Christoph ; Hable, Volker ; Dollinger, Günther ; Cremer, Thomas ; Friedl, Anna A
Publisher:Dordrecht: Springer-Verlag
Journal title:Chromosome research, 2011-10, Vol.19 (7), p.883-899
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Hypoxia induces rapid changes to histone methylation and reprograms chromatin

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Pediatric non–Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes

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Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans

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Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans

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Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling

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KDM5A mutations identified in autism spectrum disorder using forward genetics

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NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern

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Mechanism of histone demethylase KDM5A in osteoporotic fracture healing through epigenetic regulation of the miR-495/SKP2/Runx2 axis

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AUP1 transcriptionally activated by KDM5B reprograms lipid metabolism to promote the malignant progression of cervical cancer

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The KDM5A/HOXA5 axis regulates osteosarcoma progression via activating the Wnt/β-catenin pathway

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Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion

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Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis

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Histone Demethylase Retinoblastoma Binding Protein 2 is Overexpressed in Hepatocellular Carcinoma and Negatively Regulated by hsa-miR-212

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Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A

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Gene mutation analysis using next‐generation sequencing and its clinical significance in patients with myeloid neoplasm: A multi‐center study from China

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KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance

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Variable Phenotypes of Epilepsy, Intellectual Disability, and Schizophrenia Caused by 12p13.33–p13.32 Terminal Microdeletion in a Korean Family: A Case Report and Literature Review

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Drug-Tolerant Cancer Cells Show Reduced Tumor-Initiating Capacity: Depletion of CD44+ Cells and Evidence for Epigenetic Mechanisms

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JARID1A, JMY, and PTGER4 Polymorphisms Are Related to Ankylosing Spondylitis in Chinese Han Patients: A Case-Control Study

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Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4

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