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ArticlesPeer ReviewedFull Text
Oxidative stress as a key modulator of cell fate decision in osteoarthritis and osteoporosis: a narrative review
Author / Creator:Riegger, Jana ; Schoppa, Astrid ; Ruths, Leonie ; Haffner-Luntzer, Melanie ; Ignatius, Anita
Publisher:Wrocław: BioMed Central
Journal title:Cellular & molecular biology letters, 2023-09, Vol.28 (1), p.76-76, Article 76
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Pathomechanisms of Posttraumatic Osteoarthritis: Chondrocyte Behavior and Fate in a Precarious Environment
Author / Creator:Riegger, Jana ; Brenner, Rolf E.
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2020-02, Vol.21 (5), p.1560
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Increase of cell surface vimentin is associated with vimentin network disruption and subsequent stress-induced premature senescence in human chondrocytes
Author / Creator:Riegger, Jana ; Brenner, Rolf E
Publisher:Cambridge: eLife Science Publications, Ltd
Journal title:eLife, 2023-10, Vol.12
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In Vitro Characterization of Doxorubicin-Mediated Stress-Induced Premature Senescence in Human Chondrocytes
Author / Creator:Kirsch, Valeria ; Ramge, Jan-Moritz ; Schoppa, Astrid ; Ignatius, Anita ; Riegger, Jana
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-03, Vol.11 (7), p.1106
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Osteoblast lineage Sod2 deficiency leads to an osteoporosis-like phenotype in mice
Author / Creator:Schoppa, Astrid M. ; Chen, Xiangxu ; Ramge, Jan-Moritz ; Vikman, Anna ; Fischer, Verena ; Haffner-Luntzer, Melanie ; Riegger, Jana ; Tuckermann, Jan ; Scharffetter-Kochanek, Karin ; Ignatius, Anita
Publisher:England: The Company of Biologists Ltd
Journal title:Disease models & mechanisms, 2022-05, Vol.15 (5)
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Terminal Complement Activation Is Induced by Factors Released from Endplate Tissue of Disc Degeneration Patients and Stimulates Expression of Catabolic Enzymes in Annulus Fibrosus Cells
Author / Creator:Kuhn, Amelie ; Riegger, Jana ; Teixeira, Graciosa Q. ; Huber-Lang, Markus ; Lambris, John D. ; Neidlinger-Wilke, Cornelia ; Brenner, Rolf E.
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2023-03, Vol.12 (6), p.887
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Functional Loss of Terminal Complement Complex Protects Rabbits from Injury-Induced Osteoarthritis on Structural and Cellular Level
Author / Creator:Riegger, Jana ; Joos, Helga ; Möhler, Valentin ; Leucht, Frank ; Rading, Katrin ; Kubisch, Christian ; Ignatius, Anita ; Huber-Lang, Markus ; Brenner, Rolf E.
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-01, Vol.13 (2), p.216
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Analysis of Intervertebral Disc Degeneration Induced by Endplate Drilling or Needle Puncture in Complement C6-Sufficient and C6-Deficient Rabbits
Author / Creator:Kuhn, Amelie ; Huber-Lang, Markus ; Weckbach, Sebastian ; Riegger, Jana ; Teixeira, Graciosa Q. ; Rasche, Volker ; Fiedler, Jörg ; Neidlinger-Wilke, Cornelia ; Brenner, Rolf E.
Publisher:Switzerland: MDPI AG
Journal title:Biomedicines, 2024-08, Vol.12 (8), p.1692
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Evidence of necroptosis in osteoarthritic disease: investigation of blunt mechanical impact as possible trigger in regulated necrosis
Author / Creator:Riegger, Jana ; Brenner, Rolf E.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-09, Vol.10 (10), p.683-12, Article 683
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Senolytic therapy combining Dasatinib and Quercetin restores the chondrogenic phenotype of human osteoarthritic chondrocytes by the release of pro‐anabolic mediators
Author / Creator:Maurer, Svenja ; Kirsch, Valeria ; Ruths, Leonie ; Brenner, Rolf E. ; Riegger, Jana
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2025-01, Vol.24 (1), p.e14361-n/a
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The Hexosamine Biosynthetic Pathway as a Therapeutic Target after Cartilage Trauma: Modification of Chondrocyte Survival and Metabolism by Glucosamine Derivatives and PUGNAc in an Ex Vivo Model
Author / Creator:Riegger, Jana ; Baumert, Julia ; Zaucke, Frank ; Brenner, Rolf E.
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2021-07, Vol.22 (14), p.7247
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The Expression of Thrombospondin-4 Correlates with Disease Severity in Osteoarthritic Knee Cartilage
Author / Creator:Maly, Kathrin ; Schaible, Inna ; Riegger, Jana ; Brenner, Rolf E. ; Meurer, Andrea ; Zaucke, Frank
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-01, Vol.20 (2), p.447
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Initial Harm Reduction by N-Acetylcysteine Alleviates Cartilage Degeneration after Blunt Single-Impact Cartilage Trauma in Vivo
Author / Creator:Riegger, Jana ; Leucht, Frank ; Palm, Hans-Georg ; Ignatius, Anita ; Brenner, Rolf E.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-06, Vol.20 (12), p.2916
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Hypothermia Promotes Cell-Protective and Chondroprotective Effects After Blunt Cartilage Trauma
Author / Creator:Riegger, Jana ; Zimmermann, Madeleine ; Joos, Helga ; Kappe, Thomas ; Brenner, Rolf E.
Publisher:Los Angeles, CA: SAGE Publications
Journal title:The American journal of sports medicine, 2018-02, Vol.46 (2), p.420-430
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Interleukin-1β and cathepsin D modulate formation of the terminal complement complex in cultured human disc tissue
Author / Creator:Teixeira, Graciosa Q. ; Yong, Zhiyao ; Kuhn, Amelie ; Riegger, Jana ; Goncalves, Raquel M. ; Ruf, Michael ; Mauer, Uwe M. ; Huber-Lang, Markus ; Ignatius, Anita ; Brenner, Rolf E. ; Neidlinger-Wilke, Cornelia
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:European spine journal, 2021-08, Vol.30 (8), p.2247-2256
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Striking a new path in reducing cartilage breakdown: combination of antioxidative therapy and chondroanabolic stimulation after blunt cartilage trauma
Author / Creator:Riegger, Jana ; Joos, Helga ; Palm, Hans‐Georg ; Friemert, Benedikt ; Reichel, Heiko ; Ignatius, Anita ; Brenner, Rolf E.
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2018-01, Vol.22 (1), p.77-88
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Terminal complement complex formation is associated with intervertebral disc degeneration
Author / Creator:Teixeira, Graciosa Q. ; Yong, Zhiyao ; Goncalves, Raquel M. ; Kuhn, Amelie ; Riegger, Jana ; Brisby, Helena ; Barreto Henriksson, Helena ; Ruf, Michael ; Nerlich, Andreas ; Mauer, Uwe M. ; Ignatius, Anita ; Brenner, Rolf E. ; Neidlinger-Wilke, Cornelia
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:European spine journal, 2021-01, Vol.30 (1), p.217-226
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Differential Interactive Effects of Cartilage Traumatization and Blood Exposure In Vitro and In Vivo
Author / Creator:Joos, Helga ; Leucht, Frank ; Riegger, Jana ; Hogrefe, Cathrin ; Fiedler, Jörg ; Dürselen, Lutz ; Reichel, Heiko ; Ignatius, Anita ; Brenner, Rolf E.
Publisher:Los Angeles, CA: SAGE Publications
Journal title:The American journal of sports medicine, 2015-11, Vol.43 (11), p.2822-2832
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Serum Cartilage Oligomeric Matrix Protein in Late-Stage Osteoarthritis: Association with Clinical Features, Renal Function, and Cardiovascular Biomarkers
Author / Creator:Riegger, Jana ; Rehm, Martin ; Büchele, Gisela ; Brenner, Hermann ; Günther, Klaus-Peter ; Rothenbacher, Dietrich ; Brenner, Rolf E.
Publisher:Switzerland: MDPI AG
Journal title:Journal of clinical medicine, 2020-01, Vol.9 (1), p.268
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Oxidative stress as a key modulator of cell fate decision in osteoarthritis and osteoporosis: a narrative review

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Pathomechanisms of Posttraumatic Osteoarthritis: Chondrocyte Behavior and Fate in a Precarious Environment

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Increase of cell surface vimentin is associated with vimentin network disruption and subsequent stress-induced premature senescence in human chondrocytes

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In Vitro Characterization of Doxorubicin-Mediated Stress-Induced Premature Senescence in Human Chondrocytes

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Osteoblast lineage Sod2 deficiency leads to an osteoporosis-like phenotype in mice

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Terminal Complement Activation Is Induced by Factors Released from Endplate Tissue of Disc Degeneration Patients and Stimulates Expression of Catabolic Enzymes in Annulus Fibrosus Cells

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Functional Loss of Terminal Complement Complex Protects Rabbits from Injury-Induced Osteoarthritis on Structural and Cellular Level

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Analysis of Intervertebral Disc Degeneration Induced by Endplate Drilling or Needle Puncture in Complement C6-Sufficient and C6-Deficient Rabbits

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Evidence of necroptosis in osteoarthritic disease: investigation of blunt mechanical impact as possible trigger in regulated necrosis

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Senolytic therapy combining Dasatinib and Quercetin restores the chondrogenic phenotype of human osteoarthritic chondrocytes by the release of pro‐anabolic mediators

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The Hexosamine Biosynthetic Pathway as a Therapeutic Target after Cartilage Trauma: Modification of Chondrocyte Survival and Metabolism by Glucosamine Derivatives and PUGNAc in an Ex Vivo Model

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The Expression of Thrombospondin-4 Correlates with Disease Severity in Osteoarthritic Knee Cartilage

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Initial Harm Reduction by N-Acetylcysteine Alleviates Cartilage Degeneration after Blunt Single-Impact Cartilage Trauma in Vivo

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Hypothermia Promotes Cell-Protective and Chondroprotective Effects After Blunt Cartilage Trauma

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Interleukin-1β and cathepsin D modulate formation of the terminal complement complex in cultured human disc tissue

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Striking a new path in reducing cartilage breakdown: combination of antioxidative therapy and chondroanabolic stimulation after blunt cartilage trauma

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Terminal complement complex formation is associated with intervertebral disc degeneration

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Differential Interactive Effects of Cartilage Traumatization and Blood Exposure In Vitro and In Vivo

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Serum Cartilage Oligomeric Matrix Protein in Late-Stage Osteoarthritis: Association with Clinical Features, Renal Function, and Cardiovascular Biomarkers

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