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Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial
Author / Creator:McInnes, Iain B, Prof ; Mease, Philip J, Prof ; Kirkham, Bruce, MD ; Kavanaugh, Arthur, Prof ; Ritchlin, Christopher T, Prof ; Rahman, Proton, Prof ; van der Heijde, Désirée, Prof ; Landewé, Robert, Prof ; Conaghan, Philip G, Prof ; Gottlieb, Alice B, Prof ; Richards, Hanno, MD ; Pricop, Luminita, MD ; Ligozio, Gregory, MSc ; Patekar, Manmath, MD ; Mpofu, Shephard, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2015-09, Vol.386 (9999), p.1137-1146
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Efficacy and safety of secukinumab administration by autoinjector in patients with psoriatic arthritis: results from a randomized, placebo-controlled trial (FUTURE 3)
Author / Creator:Nash, Peter ; Mease, Philip J. ; McInnes, Iain B. ; Rahman, Proton ; Ritchlin, Christopher T. ; Blanco, Ricardo ; Dokoupilova, Eva ; Andersson, Mats ; Kajekar, Radhika ; Mpofu, Shephard ; Pricop, Luminita
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2018-03, Vol.20 (1), p.47-11, Article 47
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Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis
Author / Creator:Bouta, Echoe M. ; Bell, Richard D. ; Rahimi, Homaira ; Xing, Lianping ; Wood, Ronald W. ; Bingham, Clifton O. ; Ritchlin, Christopher T. ; Schwarz, Edward M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Rheumatology, 2018-02, Vol.14 (2), p.94-106
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Single-cell transcriptomics of popliteal lymphatic vessels and peripheral veins reveals altered lymphatic muscle and immune cell populations in the TNF-Tg arthritis model
Author / Creator:Kenney, H. Mark ; Wu, Chia-Lung ; Loiselle, Alayna E. ; Xing, Lianping ; Ritchlin, Christopher T. ; Schwarz, Edward M.
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2022-03, Vol.24 (1), p.64-64, Article 64
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Persistent popliteal lymphatic muscle cell coverage defects despite amelioration of arthritis and recovery of popliteal lymphatic vessel function in TNF-Tg mice following anti-TNF therapy
Author / Creator:Kenney, H. Mark ; Peng, Yue ; Bell, Richard D. ; Wood, Ronald W. ; Xing, Lianping ; Ritchlin, Christopher T. ; Schwarz, Edward M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-07, Vol.12 (1), p.12751-13, Article 12751
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High-throughput micro-CT analysis identifies sex-dependent biomarkers of erosive arthritis in TNF-Tg mice and differential response to anti-TNF therapy
Author / Creator:Kenney, H. Mark ; Chen, Kiana L. ; Schnur, Lindsay ; Fox, Jeffrey I. ; Wood, Ronald W. ; Xing, Lianping ; Ritchlin, Christopher T. ; Rahimi, Homaira ; Schwarz, Edward M. ; Awad, Hani A.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-07, Vol.19 (7), p.e0305623
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Lineage tracing reveals evidence of a popliteal lymphatic muscle progenitor cell that is distinct from skeletal and vascular muscle progenitors
Author / Creator:Kenney, H. Mark ; Bell, Richard D. ; Masters, Elysia A. ; Xing, Lianping ; Ritchlin, Christopher T. ; Schwarz, Edward M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-10, Vol.10 (1), p.18088-18088, Article 18088
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iNOS dependent and independent phases of lymph node expansion in mice with TNF-induced inflammatory-erosive arthritis
Author / Creator:Bell, Richard D. ; Slattery, Pamelia N. ; Wu, Emily K. ; Xing, Lianping ; Ritchlin, Christopher T. ; Schwarz, Edward M.
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2019-11, Vol.21 (1), p.240-240, Article 240
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Implementation of automated behavior metrics to evaluate voluntary wheel running effects on inflammatory-erosive arthritis and interstitial lung disease in TNF-Tg mice
Author / Creator:Kenney, H. Mark ; Wood, Ronald W. ; Ramirez, Gabriel ; Bell, Richard D. ; Chen, Kiana L. ; Schnur, Lindsay ; Rahimi, Homaira ; Korman, Benjamin D. ; Xing, Lianping ; Ritchlin, Christopher T. ; Schwarz, Edward M. ; Cole, Calvin L.
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2023-02, Vol.25 (1), p.17-17, Article 17
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The effect of guselkumab on inhibiting radiographic progression in patients with active psoriatic arthritis: study protocol for APEX, a Phase 3b, multicenter, randomized, double-blind, placebo-control...
Author / Creator:Ritchlin, Christopher T. ; Coates, Laura C. ; Mease, Philip J. ; van der Heijde, Désirée ; Song, Jiao ; Jiang, Yusang ; Shawi, May ; Kollmeier, Alexa P. ; Rahman, Proton
Publisher:England: BioMed Central Ltd
Journal title:Current controlled trials in cardiovascular medicine, 2023-01, Vol.24 (1), p.22-22, Article 22
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ArticlesPeer ReviewedFull Text
Brodalumab, an Anti-IL17RA Monoclonal Antibody, in Psoriatic Arthritis
Author / Creator:Mease, Philip J. ; Genovese, Mark C. ; Greenwald, Maria W. ; Ritchlin, Christopher T. ; Beaulieu, André D. ; Deodhar, Atul ; Newmark, Richard ; Feng, JingYuan ; Erondu, Ngozi ; Nirula, Ajay
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-06, Vol.370 (24), p.2295-2306
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Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials
Author / Creator:Norton, Hillary ; Sliwinska-Stanczyk, Paula ; Hala, Tomas ; El-Zorkany, Bassel ; Stockert, Lori ; Mundayat, Rajiv ; Wang, Lisy ; Ritchlin, Christopher T.
Publisher:Cheshire: Springer Healthcare
Journal title:Rheumatology and therapy., 2025-02, Vol.12 (1), p.67-84
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ArticlesPeer ReviewedFull Text
Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential
Author / Creator:Rahimi, Homaira ; Bell, Richard ; Bouta, Echoe M. ; Wood, Ronald W. ; Xing, Lianping ; Ritchlin, Christopher T. ; Schwarz, Edward M.
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2016-09, Vol.18 (1), p.194-194, Article 194
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Psoriatic Arthritis
Author / Creator:Ritchlin, Christopher T ; Colbert, Robert A ; Gladman, Dafna D
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-03, Vol.376 (10), p.957-970
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Guselkumab, an inhibitor of the IL-23p19 subunit, provides sustained improvement in signs and symptoms of active psoriatic arthritis: 1 year results of a phase III randomised study of patients who wer...
Author / Creator:Ritchlin, Christopher T ; Helliwell, Philip S ; Boehncke, Wolf-Henning ; Soriano, Enrique R ; Hsia, Elizabeth C ; Kollmeier, Alexa P ; Chakravarty, Soumya D ; Zazzetti, Federico ; Subramanian, Ramanand A ; Xu, Xie L ; Zuraw, Qing C ; Sheng, Shihong ; Jiang, Yusang ; Agarwal, Prasheen ; Zhou, Bei ; Zhuang, Yanli ; Shawi, May ; Karyekar, Chetan S ; Deodhar, Atul
Publisher:England: EULAR
Journal title:Rheumatic & musculoskeletal diseases open, 2021-02, Vol.7 (1), p.e001457
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Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study a...
Author / Creator:Coates, Laura C ; Landewé, Robert ; McInnes, Iain B ; Mease, Philip J ; Ritchlin, Christopher T ; Tanaka, Yoshiya ; Asahina, Akihiko ; Behrens, Frank ; Gladman, Dafna D ; Gossec, Laure ; Orbai, Ana-Maria ; Gottlieb, Alice B ; Warren, Richard B ; Ink, Barbara ; Bajracharya, Rajan ; Shende, Vishvesh ; Coarse, Jason ; Merola, Joseph F
Publisher:England: EULAR
Journal title:Rheumatic & musculoskeletal diseases open, 2024-02, Vol.10 (1), p.e003855
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CD16 (FcRγIII) as a potential marker of osteoclast precursors in psoriatic arthritis
Author / Creator:Chiu, Yahui Grace ; Shao, Tianmeng ; Feng, Changyong ; Mensah, Kofi A ; Thullen, Michael ; Schwarz, Edward M ; Ritchlin, Christopher T
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2010-01, Vol.12 (1), p.R14-R14, Article R14
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Home Phototherapy Improves Access to Dermatologic Care: A Novel Stakeholder Alliance to Facilitate Its Implementation
Author / Creator:Bawany, Fatima ; Ryan Wolff, Julie ; Ritchlin, Christopher T ; Tausk, Francisco
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Clinical, cosmetic and investigational dermatology, 2023-01, Vol.16, p.1175-1180
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Sustained and improved guselkumab response in patients with active psoriatic arthritis regardless of baseline demographic and disease characteristics: pooled results through week 52 of two phase III,...
Author / Creator:Ritchlin, Christopher T ; Mease, Philip J ; Boehncke, Wolf-Henning ; Tesser, John ; Schiopu, Elena ; Chakravarty, Soumya D ; Kollmeier, Alexa P ; Xu, Xie L ; Shawi, May ; Jiang, Yusang ; Sheng, Shihong ; Wang, Yanli ; Xu, Stephen ; Merola, Joseph F ; McInnes, Iain B ; Deodhar, Atul
Publisher:England: EULAR
Journal title:Rheumatic & musculoskeletal diseases open, 2022-03, Vol.8 (1), p.e002195
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Clinically relevant patient clusters identified by machine learning from the clinical development programme of secukinumab in psoriatic arthritis
Author / Creator:Pournara, Effie ; Kormaksson, Matthias ; Nash, Peter ; Ritchlin, Christopher T ; Kirkham, Bruce W ; Ligozio, Gregory ; Pricop, Luminita ; Ogdie, Alexis ; Coates, Laura C ; Schett, Georg ; McInnes, Iain B
Publisher:England: EULAR
Journal title:Rheumatic & musculoskeletal diseases open, 2021-11, Vol.7 (3), p.e001845
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Showing 1 to 20 of 84 results

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Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial

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Efficacy and safety of secukinumab administration by autoinjector in patients with psoriatic arthritis: results from a randomized, placebo-controlled trial (FUTURE 3)

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Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis

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Single-cell transcriptomics of popliteal lymphatic vessels and peripheral veins reveals altered lymphatic muscle and immune cell populations in the TNF-Tg arthritis model

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Persistent popliteal lymphatic muscle cell coverage defects despite amelioration of arthritis and recovery of popliteal lymphatic vessel function in TNF-Tg mice following anti-TNF therapy

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High-throughput micro-CT analysis identifies sex-dependent biomarkers of erosive arthritis in TNF-Tg mice and differential response to anti-TNF therapy

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Lineage tracing reveals evidence of a popliteal lymphatic muscle progenitor cell that is distinct from skeletal and vascular muscle progenitors

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iNOS dependent and independent phases of lymph node expansion in mice with TNF-induced inflammatory-erosive arthritis

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Implementation of automated behavior metrics to evaluate voluntary wheel running effects on inflammatory-erosive arthritis and interstitial lung disease in TNF-Tg mice

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The effect of guselkumab on inhibiting radiographic progression in patients with active psoriatic arthritis: study protocol for APEX, a Phase 3b, multicenter, randomized, double-blind, placebo-control...

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Brodalumab, an Anti-IL17RA Monoclonal Antibody, in Psoriatic Arthritis

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Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials

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Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential

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Psoriatic Arthritis

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Guselkumab, an inhibitor of the IL-23p19 subunit, provides sustained improvement in signs and symptoms of active psoriatic arthritis: 1 year results of a phase III randomised study of patients who wer...

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Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study a...

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CD16 (FcRγIII) as a potential marker of osteoclast precursors in psoriatic arthritis

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Home Phototherapy Improves Access to Dermatologic Care: A Novel Stakeholder Alliance to Facilitate Its Implementation

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Sustained and improved guselkumab response in patients with active psoriatic arthritis regardless of baseline demographic and disease characteristics: pooled results through week 52 of two phase III,...

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Clinically relevant patient clusters identified by machine learning from the clinical development programme of secukinumab in psoriatic arthritis

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