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28 results for Safrit,+Jeffrey+T

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ArticlesPeer ReviewedFull Text
Intranasal plus subcutaneous prime vaccination with a dual antigen COVID-19 vaccine elicits T-cell and antibody responses in mice
Author / Creator:Rice, Adrian ; Verma, Mohit ; Shin, Annie ; Zakin, Lise ; Sieling, Peter ; Tanaka, Shiho ; Balint, Joseph ; Dinkins, Kyle ; Adisetiyo, Helty ; Morimoto, Brett ; Higashide, Wendy ; Anders Olson, C. ; Mody, Shivani ; Spilman, Patricia ; Gabitzsch, Elizabeth ; Safrit, Jeffrey T. ; Rabizadeh, Shahrooz ; Niazi, Kayvan ; Soon-Shiong, Patrick
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-07, Vol.11 (1), p.14917-14917, Article 14917
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SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques
Author / Creator:Farinre, Omotayo ; Anaya, Tzoalli ; King, Alexis C ; Endrias, Kedan ; Hébert, Anne H ; Hill, Alison L ; Jean, Sherrie ; Wood, Jennifer S ; Ehnert, Stephanie ; Liang, Shan ; Laird, Gregory M ; Mason, Rosemarie D ; Roederer, Mario ; Safrit, Jeffrey T ; Mavigner, Maud ; Chahroudi, Ann
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2025-01, Vol.21 (1), p.e1012863
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Combinatorial immunotherapy of N-803 (IL-15 superagonist) and dinutuximab with ex vivo expanded natural killer cells significantly enhances in vitro cytotoxicity against GD2+ pediatric solid tumors an...
Author / Creator:Chu, Yaya ; Nayyar, Gaurav ; Jiang, Susiyan ; Rosenblum, Jeremy M. ; Soon-Shiong, Patrick ; Safrit, Jeffrey T ; Lee, Dean A. ; Cairo, Mitchell S.
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-07, Vol.9 (7), p.e002267
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Biotech's role in advancing HIV vaccine development
Author / Creator:Tatoud, Roger ; Brander, Christian ; Hwang, Carey ; Kennelly, Jo ; Lu, Shan ; O'Neil, Kevin ; Safrit, Jeffrey T ; Benhayoun, Iris ; Firmat, Julieta ; Barriere, Nelli
Publisher:United States: Taylor & Francis Ltd
Journal title:Emerging microbes & infections, 2024-12, Vol.13 (1), p.2384460
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Conventional early infant diagnosis in Lesotho from specimen collection to results usage to manage patients: Where are the bottlenecks?
Author / Creator:Tiam, Appolinaire ; Gill, Michelle M ; Hoffman, Heather J ; Isavwa, Anthony ; Mokone, Mafusi ; Foso, Matokelo ; Safrit, Jeffrey T ; Mofenson, Lynne M ; Tylleskär, Thorkild ; Guay, Laura
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-10, Vol.12 (10), p.e0184769-e0184769
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Novel cytokine–antibody fusion protein, N-820, to enhance the functions of ex vivo expanded natural killer cells against Burkitt lymphoma
Author / Creator:Chu, Yaya ; Nayyar, Gaurav ; Kham Su, Nang ; Rosenblum, Jeremy M ; Soon-Shiong, Patrick ; Lee, John ; Safrit, Jeffrey T ; Barth, Matthew ; Lee, Dean ; Cairo, Mitchell S
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2020-10, Vol.8 (2), p.e001238
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HIV monoclonal antibodies: a new opportunity to further reduce mother-to-child HIV transmission
Author / Creator:Voronin, Yegor ; Mofenson, Lynne M ; Cunningham, Coleen K ; Fowler, Mary G ; Kaleebu, Pontiano ; McFarland, Elizabeth J ; Safrit, Jeffrey T ; Graham, Barney S ; Snow, William
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2014-04, Vol.11 (4), p.e1001616-e1001616
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Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: an...
Author / Creator:Chi, Benjamin H, Dr ; Sinkala, Moses, MBChB ; Mbewe, Felistas, BSc ; Cantrell, Ronald A, MPH ; Kruse, Gina, MSc ; Chintu, Namwinga, MBChB ; Aldrovandi, Grace M, MD ; Stringer, Elizabeth M, MD ; Kankasa, Chipepo, MD ; Safrit, Jeffrey T, PhD ; Stringer, Jeffrey SA, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2007-11, Vol.370 (9600), p.1698-1705
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Enhanced SIV Replication and Accelerated Progression to AIDS in Macaques Primed to Mount a CD4 T Cell Response to the SIV Envelope Protein
Author / Creator:Staprans, Silvija I. ; Barry, Ashley P. ; Silvestri, Guido ; Safrit, Jeffrey T. ; Kozyr, Natalia ; Sumpter, Beth ; Nguyen, Hanh ; McClure, Harold ; Montefiori, David ; Cohen, Jeffrey I. ; Feinberg, Mark B. ; Gallo, Robert C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (35), p.13026-13031
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ArticlesPeer ReviewedFull Text
Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
Author / Creator:McBrien, Julia Bergild ; Mavigner, Maud ; Franchitti, Lavinia ; Smith, S. Abigail ; White, Erick ; Tharp, Gregory K. ; Walum, Hasse ; Busman-Sahay, Kathleen ; Aguilera-Sandoval, Christian R. ; Thayer, William O. ; Spagnuolo, Rae Ann ; Kovarova, Martina ; Wahl, Angela ; Cervasi, Barbara ; Margolis, David M. ; Vanderford, Thomas H. ; Carnathan, Diane G. ; Paiardini, Mirko ; Lifson, Jeffrey D. ; Lee, John H. ; Safrit, Jeffrey T. ; Bosinger, Steven E. ; Estes, Jacob D. ; Derdeyn, Cynthia A. ; Garcia, J. Victor ; Kulpa, Deanna A. ; Chahroudi, Ann ; Silvestri, Guido
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-02, Vol.578 (7793), p.154-159
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Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial
Author / Creator:Miller, Jeffrey S. ; Davis, Zachary B. ; Helgeson, Erika ; Reilly, Cavan ; Thorkelson, Ann ; Anderson, Jodi ; Lima, Noemia S. ; Jorstad, Siri ; Hart, Geoffrey T. ; Lee, John H. ; Safrit, Jeffrey T. ; Wong, Hing ; Cooley, Sarah ; Gharu, Lavina ; Chung, Hyunsoo ; Soon-Shiong, Patrick ; Dobrowolski, Curtis ; Fletcher, Courtney V. ; Karn, Jonathan ; Douek, Daniel C. ; Schacker, Timothy W.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2022-02, Vol.28 (2), p.392-400
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Adaptive Evolution of Human Immunodeficiency Virus-Type 1 During the Natural Course of Infection
Author / Creator:Wolinsky, Steven M. ; Bette T. M. Korber ; Neumann, Avidan U. ; Daniels, Michael ; Kunstman, Kevin J. ; Whetsell, Amy J. ; Furtado, Manohar R. ; Cao, Yunzhen ; Ho, David D. ; Safrit, Jeffrey T. ; Koup, Richard A.
Publisher:Washington, DC: American Society for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 1996-04, Vol.272 (5261), p.537-542
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AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques
Author / Creator:Dashti, Amir ; Sukkestad, Sophia ; Horner, Anna M. ; Neja, Margaret ; Siddiqi, Zain ; Waller, Chevaughn ; Goldy, Jordan ; Monroe, Dominique ; Lin, Alice ; Schoof, Nils ; Singh, Vidisha ; Mavigner, Maud ; Lifson, Jeffrey D. ; Deleage, Claire ; Tuyishime, Marina ; Falcinelli, Shane D. ; King, Hannah A. D. ; Ke, Ruian ; Mason, Rosemarie D. ; Archin, Nancie M. ; Dunham, Richard M. ; Safrit, Jeffrey T. ; Jean, Sherrie ; Perelson, Alan S. ; Margolis, David M. ; Ferrari, Guido ; Roederer, Mario ; Silvestri, Guido ; Chahroudi, Ann
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2023-10, Vol.29 (10), p.2535-2546
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The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques
Author / Creator:Webb, Gabriela M ; Molden, Jhomary ; Busman-Sahay, Kathleen ; Abdulhaqq, Shaheed ; Wu, Helen L ; Weber, Whitney C ; Bateman, Katherine B ; Reed, Jason S ; Northrup, Mina ; Maier, Nicholas ; Tanaka, Shiho ; Gao, Lina ; Davey, Brianna ; Carpenter, Benjamin L ; Axthelm, Michael K ; Stanton, Jeffrey J ; Smedley, Jeremy ; Greene, Justin M ; Safrit, Jeffrey T ; Estes, Jacob D ; Skinner, Pamela J ; Sacha, Jonah B
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2020-03, Vol.16 (3), p.e1008339
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Status of vaccine research and development of vaccines for HIV-1
Author / Creator:Safrit, Jeffrey T ; Fast, Patricia E ; Gieber, Lisa ; Kuipers, Hester ; Dean, Hansi J ; Koff, Wayne C
Publisher:Netherlands: Elsevier Ltd
Journal title:Vaccine, 2016-06, Vol.34 (26), p.2921-2925
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Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
Author / Creator:McBrien, Julia Bergild ; Mavigner, Maud ; Franchitti, Lavinia ; Smith, S. Abigail ; White, Erick ; Tharp, Gregory K. ; Walum, Hasse ; Busman-Sahay, Kathleen ; Aguilera-Sandoval, Christian R. ; Thayer, William O. ; Spagnuolo, Rae Ann ; Kovarova, Martina ; Wahl, Angela ; Cervasi, Barbara ; Margolis, David M. ; Vanderford, Thomas H. ; Carnathan, Diane G. ; Paiardini, Mirko ; Lifson, Jeffrey D. ; Lee, John H. ; Safrit, Jeffrey T. ; Bosinger, Steven E. ; Estes, Jacob D. ; Derdeyn, Cynthia A. ; Garcia, J. Victor ; Kulpa, Deanna A. ; Chahroudi, Ann ; Silvestri, Guido
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-02, Vol.578 (7796), p.E21-E21
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Visualization and quantification of T cell–mediated cytotoxicity using cell-permeable fluorogenic caspase substrates
Author / Creator:Liu, Luzheng ; Chahroudi, Ann ; Silvestri, Guido ; Wernett, Mary E. ; Kaiser, William J. ; Safrit, Jeffrey T. ; Komoriya, Akira ; Altman, John D. ; Packard, Beverly Z. ; Feinberg, Mark B.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2002-02, Vol.8 (2), p.185-189
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HIV-1 Evolution and Disease Progression
Author / Creator:Nowak, Martin A. ; Anderson, Roy M. ; Boerlijst, Maarten C. ; Bonhoeffer, Sebastian ; May, Robert M. ; McMichael, Andrew J. ; Wolinsky, Steven M. ; Kunstman, Kevin J. ; Safrit, Jeffrey T. ; Koup, Richard A. ; Neumann, Avidan U. ; Bette T. M. Korber
Publisher:United States: American Society for the Advanement of Science
Journal title:Science (American Association for the Advancement of Science), 1996-11, Vol.274 (5289), p.1008-1011
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Heteologous saRNA-Prime, DNA Dual-Antigen-Boost SARS-CoV-2 Vaccination Elicits Robust Cellular Immunogenicity and Cross-Variant Neutralizing Antibodies
Author / Creator:Rice, Adrian ; Verma, Mohit ; Voigt, Emily ; Battisti, Peter ; Beaver, Sam ; Reed, Sierra ; Dinkins, Kyle ; Mody, Shivani ; Zakin, Lise ; Tanaka, Shiho ; Morimoto, Brett ; Higashide, Wendy ; Olson, C Anders ; Gabitzsch, Elizabeth R ; Safrit, Jeffrey T ; Spilman, Patricia R ; Casper, Corey ; Soon-Shiong, Patrick
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-03
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Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivale...
Author / Creator:Gabitzsch, Elizabeth ; Safrit, Jeffrey T ; Verma, Mohit ; Rice, Adrian ; Sieling, Peter ; Zakin, Lise ; Shin, Annie ; Morimoto, Brett ; Adisetiyo, Helty ; Wong, Raymond ; Bezawada, Ashish ; Dinkins, Kyle ; Balint, Joseph ; Peykov, Victor ; Garban, Hermes ; Liu, Philip ; Bone, Pete ; Bacon, Andrew ; Drew, Jeff ; Sanford, Daniel C ; Spilman, Patricia ; Sender, Lennie ; Rabizadeh, Shahrooz ; Niazi, Kayvan ; Soon-Shiong, Patrick
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-03
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Intranasal plus subcutaneous prime vaccination with a dual antigen COVID-19 vaccine elicits T-cell and antibody responses in mice

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SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques

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Combinatorial immunotherapy of N-803 (IL-15 superagonist) and dinutuximab with ex vivo expanded natural killer cells significantly enhances in vitro cytotoxicity against GD2+ pediatric solid tumors an...

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Biotech's role in advancing HIV vaccine development

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Conventional early infant diagnosis in Lesotho from specimen collection to results usage to manage patients: Where are the bottlenecks?

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Novel cytokine–antibody fusion protein, N-820, to enhance the functions of ex vivo expanded natural killer cells against Burkitt lymphoma

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HIV monoclonal antibodies: a new opportunity to further reduce mother-to-child HIV transmission

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Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: an...

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Enhanced SIV Replication and Accelerated Progression to AIDS in Macaques Primed to Mount a CD4 T Cell Response to the SIV Envelope Protein

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Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

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Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial

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Adaptive Evolution of Human Immunodeficiency Virus-Type 1 During the Natural Course of Infection

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AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques

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The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

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Status of vaccine research and development of vaccines for HIV-1

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Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

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Visualization and quantification of T cell–mediated cytotoxicity using cell-permeable fluorogenic caspase substrates

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HIV-1 Evolution and Disease Progression

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Heteologous saRNA-Prime, DNA Dual-Antigen-Boost SARS-CoV-2 Vaccination Elicits Robust Cellular Immunogenicity and Cross-Variant Neutralizing Antibodies

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Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivale...

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