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Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study
Author / Creator:Dasari, Arvind ; Lonardi, Sara ; Garcia-Carbonero, Rocio ; Elez, Elena ; Yoshino, Takayuki ; Sobrero, Alberto ; Yao, James ; García-Alfonso, Pilar ; Kocsis, Judit ; Cubillo Gracian, Antonio ; Sartore-Bianchi, Andrea ; Satoh, Taroh ; Randrian, Violaine ; Tomasek, Jiri ; Chong, Geoff ; Paulson, Andrew Scott ; Masuishi, Toshiki ; Jones, Jeremy ; Csőszi, Tibor ; Cremolini, Chiara ; Ghiringhelli, Francois ; Shergill, Ardaman ; Hochster, Howard S ; Krauss, John ; Bassam, Ali ; Ducreux, Michel ; Elme, Anneli ; Faugeras, Laurence ; Kasper, Stefan ; Van Cutsem, Eric ; Arnold, Dirk ; Nanda, Shivani ; Yang, Zhao ; Schelman, William R ; Kania, Marek ; Tabernero, Josep ; Eng, Cathy
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2023-07, Vol.402 (10395), p.41-53
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The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial
Author / Creator:Sandhu, Shahneen K, MD ; Schelman, William R, MD ; Wilding, George, MD ; Moreno, Victor, MD ; Baird, Richard D, PhD ; Miranda, Susana, BSc ; Hylands, Lucy, BSc ; Riisnaes, Ruth, FIBMS ; Forster, Martin, PhD ; Omlin, Aurelius, MD ; Kreischer, Nathan, MSc ; Thway, Khin, MD ; Gevensleben, Heidrun, MD ; Sun, Linda, PhD ; Loughney, John, PhD ; Chatterjee, Manash, PhD ; Toniatti, Carlo, PhD ; Carpenter, Christopher L, MD ; Iannone, Robert, MD ; Kaye, Stan B, Prof ; de Bono, Johann S, Prof ; Wenham, Robert M
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2013-08, Vol.14 (9), p.882-892
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Assessment of Food Effect and pH‐Dependent Drug–Drug Interactions of Fruquintinib in Healthy Subjects
Author / Creator:Gonzalez, Martha ; Yang, Zhao ; Schelman, William R. ; Zhou, Xiaofei ; Gupta, Neeraj ; Chien, Caly
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2025-03, Vol.18 (3), p.e70168-n/a
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Predictors of heterogeneity in the first-line treatment of patients with advanced/metastatic gastric cancer in the U.S
Author / Creator:Abrams, Thomas ; Hess, Lisa M. ; Zhu, Yajun Emily ; Schelman, William ; Liepa, Astra M. ; Fuchs, Charles
Publisher:Tokyo: Springer Japan
Journal title:Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2018-09, Vol.21 (5), p.738-744
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First-time-in-human study of GSK923295, a novel antimitotic inhibitor of centromere-associated protein E (CENP-E), in patients with refractory cancer
Author / Creator:Chung, Vincent ; Heath, Elisabeth I. ; Schelman, William R. ; Johnson, Brendan M. ; Kirby, Lyndon C. ; Lynch, Kerlin M. ; Botbyl, Jeffrey D. ; Lampkin, Thomas A. ; Holen, Kyle D.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Cancer chemotherapy and pharmacology, 2012-03, Vol.69 (3), p.733-741
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Ramucirumab for the treatment of patients with gastric or gastroesophageal junction cancer in community oncology practices
Author / Creator:Paulson, A. Scott ; Hess, Lisa M. ; Liepa, Astra M. ; Cui, Zhanglin Lin ; Aguilar, Kathleen M. ; Clark, Jamyia ; Schelman, William
Publisher:Tokyo: Springer Japan
Journal title:Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2018-09, Vol.21 (5), p.831-844
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A Phase I study of intermittently dosed vorinostat in combination with bortezomib in patients with advanced solid tumors
Author / Creator:Deming, Dustin A. ; Ninan, Jacob ; Bailey, Howard H. ; Kolesar, Jill M. ; Eickhoff, Jens ; Reid, Joel M. ; Ames, Matthew M. ; McGovern, Renee M. ; Alberti, Dona ; Marnocha, Rebecca ; Espinoza-Delgado, Igor ; Wright, John ; Wilding, George ; Schelman, William R.
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2014-04, Vol.32 (2), p.323-329
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A multicenter phase 1 study of γ -secretase inhibitor RO4929097 in combination with capecitabine in refractory solid tumors
Author / Creator:LoConte, Noelle K. ; Razak, Albiruni R. A. ; Ivy, Percy ; Tevaarwerk, Amye ; Leverence, Rachael ; Kolesar, Jill ; Siu, Lillian ; Lubner, Sam J. ; Mulkerin, Daniel L. ; Schelman, William R. ; Deming, Dustin A. ; Holen, Kyle D. ; Carmichael, Lakeesha ; Eickhoff, Jens ; Liu, Glenn
Publisher:Boston: Springer US
Journal title:Investigational new drugs, 2015-02, Vol.33 (1), p.169-176
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A phase I study of AT-101 with cisplatin and etoposide in patients with advanced solid tumors with an expanded cohort in extensive-stage small cell lung cancer
Author / Creator:Schelman, William R. ; Mohammed, Tabraiz A. ; Traynor, Anne M. ; Kolesar, Jill M. ; Marnocha, Rebecca M. ; Eickhoff, Jens ; Keppen, Michael ; Alberti, Dona B. ; Wilding, George ; Takebe, Naoko ; Liu, Glenn
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2014-04, Vol.32 (2), p.295-302
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A phase I study of zibotentan (ZD4054) in patients with metastatic, castrate-resistant prostate cancer
Author / Creator:Schelman, William R. ; Liu, Glenn ; Wilding, George ; Morris, Thomas ; Phung, De ; Dreicer, Robert
Publisher:Boston: Springer US
Journal title:Investigational new drugs, 2011-02, Vol.29 (1), p.118-125
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A phase I study of vorinostat in combination with bortezomib in patients with advanced malignancies
Author / Creator:Schelman, William R. ; Traynor, Anne M. ; Holen, Kyle D. ; Kolesar, Jill M. ; Attia, Steven ; Hoang, Tien ; Eickhoff, Jens ; Jiang, Zhisheng ; Alberti, Dona ; Marnocha, Rebecca ; Reid, Joel M. ; Ames, Matthew M. ; McGovern, Renee M. ; Espinoza-Delgado, Igor ; Wright, John J. ; Wilding, George ; Bailey, Howard H.
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2013-12, Vol.31 (6), p.1539-1546
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Reliability of Conclusions from Early Analyses of Real-World Data for Newly Approved Drugs in Advanced Gastric Cancer in the United States
Author / Creator:Hess, Lisa M ; Grabner, Michael ; Wang, Liya ; Liepa, Astra M ; Li, Xiaohong Ivy ; Cui, Zhanglin Lin ; Bowman, Lee ; Schelman, William R
Publisher:New Zealand: Taylor & Francis Ltd
Journal title:Pragmatic and observational research, 2020-01, Vol.11, p.27-43
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phase I study of Triapine® in combination with doxorubicin in patients with advanced solid tumors
Author / Creator:Schelman, William R ; Morgan-Meadows, Sherry ; Marnocha, Rebecca ; Lee, Fred ; Eickhoff, Jens ; Huang, Wei ; Pomplun, Marcia ; Jiang, Zhisheng ; Alberti, Dona ; Kolesar, Jill M ; Ivy, Percy ; Wilding, George ; Traynor, Anne M
Publisher:Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title:Cancer chemotherapy and pharmacology, 2009-05, Vol.63 (6), p.1147-1156
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A phase I study of sorafenib, oxaliplatin and 2 days of high dose capecitabine in advanced pancreatic and biliary tract cancer: a Wisconsin oncology network study
Author / Creator:LoConte, Noelle K. ; Holen, Kyle D. ; Schelman, William R. ; Mulkerin, Daniel L. ; Deming, Dustin A. ; Hernan, Hilary R. ; Traynor, Anne M. ; Goggins, Timothy ; Groteluschen, David ; Oettel, Kurt ; Robinson, Emily ; Lubner, Sam J.
Publisher:Boston: Springer US
Journal title:Investigational new drugs, 2013-08, Vol.31 (4), p.943-948
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Vorinostat in combination with bortezomib in patients with advanced malignancies directly alters transcription of target genes
Author / Creator:Kolesar, Jill M. ; Traynor, Anne M. ; Holen, Kyle D. ; Hoang, Tien ; Seo, Songwon ; Kim, KyungMann ; Alberti, Dona ; Espinoza-Delgado, Igor ; Wright, John J. ; Wilding, George ; Bailey, Howard H. ; Schelman, William R.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2013-09, Vol.72 (3), p.661-667
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maximum tolerated dose and biologic effects of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) in combination with irinotecan for patients with refractory solid tumors
Author / Creator:Choi, Brian S ; Alberti, Dona B ; Schelman, William R ; Kolesar, Jill M ; Thomas, James P ; Marnocha, Rebecca ; Eickhoff, Jens C ; Ivy, S. Percy ; Wilding, George ; Holen, Kyle D
Publisher:Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title:Cancer chemotherapy and pharmacology, 2010-10, Vol.66 (5), p.973-980
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Evaluation of mRNA by Q-RTPCR and protein expression by AQUA of the M2 subunit of ribonucleotide reductase (RRM2) in human tumors
Author / Creator:Kolesar, Jill ; Huang, Wei ; Eickhoff, Jens ; Hahn, Kristine ; Alberti, Dona ; Attia, Steven ; Schelman, William ; Holen, Kyle ; Traynor, Anne ; Ivy, Percy ; Wilding, George
Publisher:Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title:Cancer chemotherapy and pharmacology, 2009-06, Vol.64 (1), p.79-86
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Aggressive Adenocarcinoma of the Cervical Esophagus : Importance of a Multidisciplinary Approach
Author / Creator:Fashoyin, Adedayo ; Hartig, Gregory ; Schelman, William R. ; Ritter, Mark ; Agni, Rashmi ; Gopal, Deepak V. ; Pfau, Patrick R. ; Weiss, Jennifer M.
Publisher:Cairo, Egypt: Hindawi Puplishing Corporation
Journal title:Case reports in gastrointestinal medicine, 2012-01, Vol.2012 (2012), p.1-3
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Dose-escalation study of fixed-dose rate gemcitabine combined with capecitabine in advanced solid malignancies
Author / Creator:Attia, Steven ; Morgan-Meadows, Sherry ; Holen, Kyle D ; Bailey, Howard H ; Eickhoff, Jens C ; Schelman, William R ; Traynor, Anne M ; Mulkerin, Daniel L ; Campbell, Toby C ; McFarland, Thomas A ; Huie, Michael S ; Cleary, James F ; Tevaarwerk, Amye J ; Alberti, Dona B ; Wilding, George ; Liu, Glenn
Publisher:Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title:Cancer chemotherapy and pharmacology, 2009-06, Vol.64 (1), p.45-51
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Phase 1/1b open-label, dose-escalation study of fruquintinib in patients with advanced solid tumors in the United States
Author / Creator:Wang-Gillam, Andrea ; Schelman, William ; Ukrainskyj, Stacey ; Chien, Caly ; Gonzalez, Martha ; Yang, Zhao ; Kania, Marek ; Yeckes-Rodin, Heather
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2023-12, Vol.41 (6), p.851-860
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Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study

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The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial

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Assessment of Food Effect and pH‐Dependent Drug–Drug Interactions of Fruquintinib in Healthy Subjects

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Predictors of heterogeneity in the first-line treatment of patients with advanced/metastatic gastric cancer in the U.S

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First-time-in-human study of GSK923295, a novel antimitotic inhibitor of centromere-associated protein E (CENP-E), in patients with refractory cancer

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Ramucirumab for the treatment of patients with gastric or gastroesophageal junction cancer in community oncology practices

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A Phase I study of intermittently dosed vorinostat in combination with bortezomib in patients with advanced solid tumors

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A multicenter phase 1 study of γ -secretase inhibitor RO4929097 in combination with capecitabine in refractory solid tumors

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A phase I study of AT-101 with cisplatin and etoposide in patients with advanced solid tumors with an expanded cohort in extensive-stage small cell lung cancer

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A phase I study of zibotentan (ZD4054) in patients with metastatic, castrate-resistant prostate cancer

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A phase I study of vorinostat in combination with bortezomib in patients with advanced malignancies

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Reliability of Conclusions from Early Analyses of Real-World Data for Newly Approved Drugs in Advanced Gastric Cancer in the United States

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phase I study of Triapine® in combination with doxorubicin in patients with advanced solid tumors

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A phase I study of sorafenib, oxaliplatin and 2 days of high dose capecitabine in advanced pancreatic and biliary tract cancer: a Wisconsin oncology network study

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Vorinostat in combination with bortezomib in patients with advanced malignancies directly alters transcription of target genes

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maximum tolerated dose and biologic effects of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) in combination with irinotecan for patients with refractory solid tumors

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Evaluation of mRNA by Q-RTPCR and protein expression by AQUA of the M2 subunit of ribonucleotide reductase (RRM2) in human tumors

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Aggressive Adenocarcinoma of the Cervical Esophagus : Importance of a Multidisciplinary Approach

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Dose-escalation study of fixed-dose rate gemcitabine combined with capecitabine in advanced solid malignancies

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Phase 1/1b open-label, dose-escalation study of fruquintinib in patients with advanced solid tumors in the United States

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