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ArticlesPeer ReviewedFull Text
Two-step multi-omics modelling of drug sensitivity in cancer cell lines to identify driving mechanisms
Author / Creator:Kusch, Nina ; Schuppert, Andreas
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-11, Vol.15 (11), p.e0238961-e0238961
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A systematic atlas of chaperome deregulation topologies across the human cancer landscape
Author / Creator:Hadizadeh Esfahani, Ali ; Sverchkova, Angelina ; Saez-Rodriguez, Julio ; Schuppert, Andreas A. ; Brehme, Marc
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2018-01, Vol.14 (1), p.e1005890-e1005890
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ArticlesPeer ReviewedFull Text
6-month mortality and readmissions of hospitalized COVID-19 patients: A nationwide cohort study of 8,679 patients in Germany
Author / Creator:Günster, Christian ; Busse, Reinhard ; Spoden, Melissa ; Rombey, Tanja ; Schillinger, Gerhard ; Hoffmann, Wolfgang ; Weber-Carstens, Steffen ; Schuppert, Andreas ; Karagiannidis, Christian
Publisher:San Francisco, CA USA: Public Library of Science
Journal title:PloS one, 2021-08, Vol.16 (8), p.e0255427-e0255427
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From hype to reality: data science enabling personalized medicine
Author / Creator:Fröhlich, Holger ; Balling, Rudi ; Beerenwinkel, Niko ; Kohlbacher, Oliver ; Kumar, Santosh ; Lengauer, Thomas ; Maathuis, Marloes H. ; Moreau, Yves ; Murphy, Susan A. ; Przytycka, Teresa M. ; Rebhan, Michael ; Röst, Hannes ; Schuppert, Andreas ; Schwab, Matthias ; Spang, Rainer ; Stekhoven, Daniel ; Sun, Jimeng ; Weber, Andreas ; Ziemek, Daniel ; Zupan, Blaz
Publisher:England: BioMed Central Ltd
Journal title:BMC medicine, 2018-08, Vol.16 (1), p.150-150, Article 150
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ArticlesPeer ReviewedFull Text
Noisecut: a python package for noise-tolerant classification of binary data using prior knowledge integration and max-cut solutions
Author / Creator:Samadi, Moein E. ; Mirzaieazar, Hedieh ; Mitsos, Alexander ; Schuppert, Andreas
Publisher:England: BioMed Central Ltd
Journal title:BMC bioinformatics, 2024-04, Vol.25 (1), p.155-155, Article 155
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ArticlesPeer ReviewedFull Text
Bayesian Population Physiologically-Based Pharmacokinetic (PBPK) Approach for a Physiologically Realistic Characterization of Interindividual Variability in Clinically Relevant Populations
Author / Creator:Krauss, Markus ; Tappe, Kai ; Schuppert, Andreas ; Kuepfer, Lars ; Goerlitz, Linus
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-10, Vol.10 (10), p.e0139423-e0139423
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ArticlesPeer ReviewedFull Text
Novel architecture for gated recurrent unit autoencoder trained on time series from electronic health records enables detection of ICU patient subgroups
Author / Creator:Merkelbach, Kilian ; Schaper, Steffen ; Diedrich, Christian ; Fritsch, Sebastian Johannes ; Schuppert, Andreas
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-03, Vol.13 (1), p.4053-4053, Article 4053
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ArticlesPeer ReviewedFull Text
Few inputs can reprogram biological networks
Author / Creator:Müller, Franz-Josef ; Schuppert, Andreas
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-10, Vol.478 (7369), p.E4-E4
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A hybrid modeling framework for generalizable and interpretable predictions of ICU mortality across multiple hospitals
Author / Creator:Samadi, Moein E. ; Guzman-Maldonado, Jorge ; Nikulina, Kateryna ; Mirzaieazar, Hedieh ; Sharafutdinov, Konstantin ; Fritsch, Sebastian Johannes ; Schuppert, Andreas
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-03, Vol.14 (1), p.5725-21, Article 5725
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A training strategy for hybrid models to break the curse of dimensionality
Author / Creator:E. Samadi, Moein ; Kiefer, Sandra ; Fritsch, Sebastian Johaness ; Bickenbach, Johannes ; Schuppert, Andreas
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2022-09, Vol.17 (9), p.e0274569-e0274569
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ArticlesPeer ReviewedFull Text
Methodological challenges in translational drug response modeling in cancer: A systematic analysis with FORESEE
Author / Creator:Schätzle, Lisa-Katrin ; Hadizadeh Esfahani, Ali ; Schuppert, Andreas
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2020-04, Vol.16 (4), p.e1007803-e1007803
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ArticlesPeer ReviewedFull Text
Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity
Author / Creator:MacArthur, Ben D. ; Sevilla, Ana ; Lenz, Michel ; Müller, Franz-Josef ; Schuldt, Berhard M. ; Schuppert, Andreas A. ; Ridden, Sonya J. ; Stumpf, Patrick S. ; Fidalgo, Miguel ; Ma’ayan, Avi ; Wang, Jianlong ; Lemischka, Ihor R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2012-11, Vol.14 (11), p.1139-1147
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ArticlesPeer ReviewedFull Text
Spike by spike frequency analysis of amperometry traces provides statistical validation of observations in the time domain
Author / Creator:Krishnan, Jeyashree ; Lian, Zeyu ; Oomen, Pieter E. ; Amir-Aref, Mohaddeseh ; He, Xiulan ; Majdi, Soodabeh ; Schuppert, Andreas ; Ewing, Andrew
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-10, Vol.14 (1), p.25142-11, Article 25142
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ArticlesPeer ReviewedFull Text
Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage
Author / Creator:Schenk, Arne ; Ghallab, Ahmed ; Hofmann, Ute ; Hassan, Reham ; Schwarz, Michael ; Schuppert, Andreas ; Schwen, Lars Ole ; Braeuning, Albert ; Teutonico, Donato ; Hengstler, Jan G. ; Kuepfer, Lars
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-07, Vol.7 (1), p.6224-13, Article 6224
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ArticlesPeer ReviewedFull Text
Biometric covariates and outcome in COVID-19 patients: are we looking close enough?
Author / Creator:Sharafutdinov, Konstantin ; Fritsch, Sebastian Johannes ; Marx, Gernot ; Bickenbach, Johannes ; Schuppert, Andreas
Publisher:London: BioMed Central Ltd
Journal title:BMC infectious diseases, 2021-11, Vol.21 (1), p.1-1136, Article 1136
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ArticlesPeer ReviewedFull Text
Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care
Author / Creator:Peine, Arne ; Hallawa, Ahmed ; Bickenbach, Johannes ; Dartmann, Guido ; Fazlic, Lejla Begic ; Schmeink, Anke ; Ascheid, Gerd ; Thiemermann, Christoph ; Schuppert, Andreas ; Kindle, Ryan ; Celi, Leo ; Marx, Gernot ; Martin, Lukas
Publisher:London: Nature Publishing Group UK
Journal title:NPJ digital medicine, 2021-02, Vol.4 (1), p.32-12, Article 32
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ArticlesPeer ReviewedFull Text
Monitoring individualized glucose levels predicts risk for bradycardia in type 2 diabetes patients with chronic kidney disease: a pilot study
Author / Creator:Farhadi Ghalati, Pejman ; E. Samadi, Moein ; Verket, Marlo ; Balfanz, Paul ; Müller-Wieland, Dirk ; Jonas, Stephan ; Napp, Andreas ; Wanner, Christoph ; Ketteler, Markus ; Vassiliadou, Athina ; Heidenreich, Stefan ; Deserno, Thomas ; Hetzel, Gudrun ; Fliser, Danilo ; Kelm, Malte ; Floege, Jürgen ; Marx, Nikolaus ; Schuppert, Andreas
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-12, Vol.14 (1), p.30290-14, Article 30290
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ArticlesPeer ReviewedFull Text
Analysis of Chest X-ray for COVID-19 Diagnosis as a Use Case for an HPC-Enabled Data Analysis and Machine Learning Platform for Medical Diagnosis Support
Author / Creator:Barakat, Chadi ; Aach, Marcel ; Schuppert, Andreas ; Brynjólfsson, Sigurður ; Fritsch, Sebastian ; Riedel, Morris
Publisher:Switzerland: MDPI AG
Journal title:Diagnostics (Basel), 2023-01, Vol.13 (3), p.391
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ArticlesPeer ReviewedFull Text
Stimulation of L‐type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells
Author / Creator:Jefri, Malvin ; Bell, Scott ; Peng, Huashan ; Hettige, Nuwan ; Maussion, Gilles ; Soubannier, Vincent ; Wu, Hanrong ; Silveira, Heika ; Theroux, Jean‐Francois ; Moquin, Luc ; Zhang, Xin ; Aouabed, Zahia ; Krishnan, Jeyashree ; O'Leary, Liam A. ; Antonyan, Lilit ; Zhang, Ying ; McCarty, Vincent ; Mechawar, Naguib ; Gratton, Alain ; Schuppert, Andreas ; Durcan, Thomas M. ; Fon, Edward A. ; Ernst, Carl
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:Stem cells translational medicine, 2020-06, Vol.9 (6), p.697-712
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ArticlesPeer ReviewedFull Text
Developing an Artificial Intelligence-Based Representation of a Virtual Patient Model for Real-Time Diagnosis of Acute Respiratory Distress Syndrome
Author / Creator:Barakat, Chadi S. ; Sharafutdinov, Konstantin ; Busch, Josefine ; Saffaran, Sina ; Bates, Declan G. ; Hardman, Jonathan G. ; Schuppert, Andreas ; Brynjólfsson, Sigurður ; Fritsch, Sebastian ; Riedel, Morris
Publisher:Switzerland: MDPI AG
Journal title:Diagnostics (Basel), 2023-06, Vol.13 (12), p.2098
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Showing 1 to 20 of 67 results

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Two-step multi-omics modelling of drug sensitivity in cancer cell lines to identify driving mechanisms

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A systematic atlas of chaperome deregulation topologies across the human cancer landscape

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6-month mortality and readmissions of hospitalized COVID-19 patients: A nationwide cohort study of 8,679 patients in Germany

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From hype to reality: data science enabling personalized medicine

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Noisecut: a python package for noise-tolerant classification of binary data using prior knowledge integration and max-cut solutions

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Bayesian Population Physiologically-Based Pharmacokinetic (PBPK) Approach for a Physiologically Realistic Characterization of Interindividual Variability in Clinically Relevant Populations

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Novel architecture for gated recurrent unit autoencoder trained on time series from electronic health records enables detection of ICU patient subgroups

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Few inputs can reprogram biological networks

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A hybrid modeling framework for generalizable and interpretable predictions of ICU mortality across multiple hospitals

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A training strategy for hybrid models to break the curse of dimensionality

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Methodological challenges in translational drug response modeling in cancer: A systematic analysis with FORESEE

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Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity

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Spike by spike frequency analysis of amperometry traces provides statistical validation of observations in the time domain

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Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage

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Biometric covariates and outcome in COVID-19 patients: are we looking close enough?

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Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care

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Monitoring individualized glucose levels predicts risk for bradycardia in type 2 diabetes patients with chronic kidney disease: a pilot study

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Analysis of Chest X-ray for COVID-19 Diagnosis as a Use Case for an HPC-Enabled Data Analysis and Machine Learning Platform for Medical Diagnosis Support

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Stimulation of L‐type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells

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Developing an Artificial Intelligence-Based Representation of a Virtual Patient Model for Real-Time Diagnosis of Acute Respiratory Distress Syndrome

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