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34 results for Scicinski,+Jan

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Newsletter articlesFull Text
Radiorx Inc, Scicinski Jan and Oronsky Bryan T File WIPO Patent Application for Organonitro Thioether Compounds and Medical Uses Thereof
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2013
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ArticlesPeer ReviewedFull Text
Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 study
Author / Creator:Reid, Tony, Prof ; Oronsky, Bryan, MD ; Scicinski, Jan, PhD ; Scribner, Curt L, MD ; Knox, Susan J, MD ; Ning, Shoucheng, MD ; Peehl, Donna M, Prof ; Korn, Ron, MD ; Stirn, Meaghan, MBA ; Carter, Corey A, MD ; Oronsky, Arnold, MD ; Taylor, Michael J, PhD ; Fitch, William L, PhD ; Cabrales, Pedro, PhD ; Kim, Michelle M, MD ; Burris, Howard A, MD ; Lao, Christopher D, MD ; Abrouk, Nacer E D, PhD ; Fanger, Gary R, PhD ; Infante, Jeffrey R, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-09, Vol.16 (9), p.1133-1142
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ArticlesPeer ReviewedFull Text
The capacity of red blood cells to reduce nitrite determines nitric oxide generation under hypoxic conditions
Author / Creator:Fens, Marcel H ; Larkin, Sandra K ; Oronsky, Bryan ; Scicinski, Jan ; Morris, Claudia R ; Kuypers, Frans A
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-07, Vol.9 (7), p.e101626
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ArticlesPeer ReviewedFull Text
A look inside the mechanistic black box: Are red blood cells the critical effectors of RRx-001 cytotoxicity?
Author / Creator:Cabrales, Pedro ; Scicinski, Jan ; Reid, Tony ; Kuypers, Frans ; Larkin, Sandra ; Fens, Marcel ; Oronsky, Arnold ; Oronsky, Bryan
Publisher:New York: Springer US
Journal title:Medical oncology (Northwood, London, England), 2016-07, Vol.33 (7), p.63-63, Article 63
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ArticlesPeer ReviewedFull Text
Partial Response to Platinum Doublets in Refractory EGFR-Positive Non-Small Cell Lung Cancer Patients after RRx-001: Evidence of Episensitization
Author / Creator:Carter, Corey A. ; Oronsky, Bryan T. ; Caroen, Scott Z. ; Scicinski, Jan J. ; Cabrales, Pedro ; Reid, Tony ; Degesys, Aiste ; Jenkins, John ; Brzezniak, Christina
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Case reports in oncology, 2016-01, Vol.9 (1), p.62-67
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ArticlesPeer ReviewedFull Text
Pulmonary Tumor Thrombotic Microangiopathy: A New Paraneoplastic Syndrome
Author / Creator:Carter, Corey A. ; Scicinski, Jan J. ; Lybeck, Harry E. ; Oronsky, Bryan T.
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Case reports in oncology, 2016-04, Vol.9 (1), p.246-248
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ArticlesPeer ReviewedFull Text
The Case of a Zebra That Was Misdiagnosed as a Horse: Pulmonary Tumor Thrombotic Microangiopathy, a New Paraneoplastic Syndrome, Mimicking PD-1-Induced Pneumonitis
Author / Creator:Carter, Corey A. ; Browning, Robert ; Oronsky, Bryan T. ; Scicinski, Jan J. ; Brzezniak, Christina
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Case reports in oncology, 2016-01, Vol.9 (1), p.68-75
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ArticlesPeer ReviewedFull Text
RRx-001-Induced Tumor Necrosis and Immune Cell Infiltration in an EGFR Mutation-Positive NSCLC with Resistance to EGFR Tyrosine Kinase Inhibitors: A Case Report
Author / Creator:Brzezniak, Christina ; Schmitz, Bruno A. ; Peterson, Paul G. ; Degesys, Aiste ; Oronsky, Bryan T. ; Scicinski, Jan J. ; Caroen, Scott Z. ; Carter, Corey A.
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Case reports in oncology, 2016-01, Vol.9 (1), p.45-50
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ArticlesPeer ReviewedFull Text
Impact of hemoglobin nitrite to nitric oxide reductase on blood transfusion for resuscitation from hemorrhagic shock
Author / Creator:Brouse, Chad ; Ortiz, Daniel ; Su, Yan ; Oronsky, Bryan ; Scicinski, Jan ; Cabrales, Pedro
Publisher:India: Medknow Publications and Media Pvt. Ltd
Journal title:Asian journal of transfusion science, 2015-01, Vol.9 (1), p.55-60
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ArticlesPeer ReviewedFull Text
A Partial Response to Reintroduced Chemotherapy in a Resistant Small Cell Lung Cancer Patient After Priming with RRx-001
Author / Creator:Oronsky, Bryan ; Caroen, Scott ; Zeman, Karen ; Quinn, Mary ; Brzezniak, Christina ; Scicinski, Jan ; Cabrales, Pedro ; Reid, Tony R. ; Trepel, Jane B. ; Abrouk, Nacer D. ; Larson, Christopher ; Oronsky, Arnold ; Lybeck, Harry E. ; Day, Regina M. ; Carter, Corey A.
Publisher:London, England: Libertas Academica
Journal title:Clinical Medicine Insights. Oncology, 2016-01, Vol.2016 (10), p.105-108
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ArticlesPeer ReviewedFull Text
RRx-001 in Refractory Small-Cell Lung Carcinoma: A Case Report of a Partial Response after a Third Reintroduction of Platinum Doublets
Author / Creator:Carter, Corey A. ; Oronsky, Bryan T. ; Caroen, Scott Z. ; Scicinski, Jan J. ; Degesys, Aiste ; Kim, Michelle M. ; Oronsky, Arnold L. ; Lybeck, Harry ; Cabrales, Pedro ; Oronsky, Neil ; Reid, Tony ; Roswarski, Joseph ; Brzezniak, Christina
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Case reports in oncology, 2016-03, Vol.9 (1), p.171-176
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ArticlesPeer ReviewedFull Text
Immune Reactivity and Pseudoprogression or Tumor Flare in a Serially Biopsied Neuroendocrine Patient Treated with the Epigenetic Agent RRx-001
Author / Creator:Carter, Corey A. ; Schmitz, Bruno ; Peterson, P. Gabriel ; Quinn, Mary ; Degesys, Aiste ; Jenkins, John ; Oronsky, Bryan ; Scicinski, Jan ; Caroen, Scott ; Reid, Tony R. ; Cabrales, Pedro ; Brzezniak, Christina
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Case reports in oncology, 2016-03, Vol.9 (1), p.164-170
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ArticlesPeer ReviewedFull Text
Partial Response in an RRx-001-Primed Patient with Refractory Small-Cell Lung Cancer after a Third Introduction of Platinum Doublets
Author / Creator:Carter, Corey A. ; Oronsky, Bryan ; Caroen, Scott ; Scicinski, Jan ; Degesys, Aiste ; Cabrales, Pedro ; Reid, Tony R. ; Brzezniak, Christina
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Case reports in oncology, 2016-05, Vol.9 (2), p.285-289
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ArticlesPeer ReviewedFull Text
Flushing Out Carcinoid Syndrome: Beneficial Effect of the Anticancer Epigenetic Agent RRx-001 in a Patient with a Treatment-Refractory Neuroendocrine Tumor
Author / Creator:Carter, Corey A. ; Degesys, Aiste ; Oronsky, Bryan ; Scicinski, Jan ; Caroen, Scott Z. ; Oronsky, Arnold L. ; Reid, Tony ; Cabrales, Pedro ; Roswarski, Joe
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Case reports in oncology, 2015-10, Vol.8 (3), p.461-465
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ArticlesPeer ReviewedFull Text
Analytical Techniques for Small Molecule Solid Phase Synthesis
Author / Creator:Scicinski, Jan J ; Congreveb, Miles S ; Kay, Corinne ; Ley, Steven V
Publisher:United Arab Emirates: Bentham Science Publishers Ltd
Journal title:Current medicinal chemistry, 2002-12, Vol.9 (23), p.2103-2127
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ArticlesPeer ReviewedFull Text
RRx-001, A novel dinitroazetidine radiosensitizer
Author / Creator:Oronsky, Bryan ; Scicinski, Jan ; Ning, Shoucheng ; Peehl, Donna ; Oronsky, Arnold ; Cabrales, Pedro ; Bednarski, Mark ; Knox, Susan
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2016-06, Vol.34 (3), p.371-377
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ArticlesPeer ReviewedFull Text
A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells
Author / Creator:Das, D Sharma ; Ray, A ; Das, A ; Song, Y ; Tian, Z ; Oronsky, B ; Richardson, P ; Scicinski, J ; Chauhan, D ; Anderson, K C
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2016-11, Vol.30 (11), p.2187-2197
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ArticlesPeer ReviewedFull Text
RRx-001, an epigenetic-based radio- and chemosensitizer, has vascular normalizing effects on SCCVII and U87 tumors
Author / Creator:Oronsky, Bryan ; Scicinski, Jan ; Cabrales, Pedro ; Minchinton, Andrew
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2016-05, Vol.8 (53), p.53-53, Article 53
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ArticlesPeer ReviewedFull Text
The immunomodulatory anticancer agent, RRx-001, induces an interferon response through epigenetic induction of viral mimicry
Author / Creator:Zhao, Hongjuan ; Ning, Shoucheng ; Nolley, Rosalie ; Scicinski, Jan ; Oronsky, Bryan ; Knox, Susan J ; Peehl, Donna M
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2017-01, Vol.9 (1), p.4-4, Article 4
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ArticlesPeer ReviewedFull Text
From METS to malaria: RRx-001, a multi-faceted anticancer agent with activity in cerebral malaria
Author / Creator:Yalcin, Ozlem ; Oronsky, Bryan ; Carvalho, Leonardo J M ; Kuypers, Frans A ; Scicinski, Jan ; Cabrales, Pedro
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2015-05, Vol.14 (1), p.218, Article 218
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Showing 1 to 20 of 34 results

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Radiorx Inc, Scicinski Jan and Oronsky Bryan T File WIPO Patent Application for Organonitro Thioether Compounds and Medical Uses Thereof

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Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 study

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The capacity of red blood cells to reduce nitrite determines nitric oxide generation under hypoxic conditions

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A look inside the mechanistic black box: Are red blood cells the critical effectors of RRx-001 cytotoxicity?

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Partial Response to Platinum Doublets in Refractory EGFR-Positive Non-Small Cell Lung Cancer Patients after RRx-001: Evidence of Episensitization

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Pulmonary Tumor Thrombotic Microangiopathy: A New Paraneoplastic Syndrome

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The Case of a Zebra That Was Misdiagnosed as a Horse: Pulmonary Tumor Thrombotic Microangiopathy, a New Paraneoplastic Syndrome, Mimicking PD-1-Induced Pneumonitis

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RRx-001-Induced Tumor Necrosis and Immune Cell Infiltration in an EGFR Mutation-Positive NSCLC with Resistance to EGFR Tyrosine Kinase Inhibitors: A Case Report

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Impact of hemoglobin nitrite to nitric oxide reductase on blood transfusion for resuscitation from hemorrhagic shock

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A Partial Response to Reintroduced Chemotherapy in a Resistant Small Cell Lung Cancer Patient After Priming with RRx-001

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RRx-001 in Refractory Small-Cell Lung Carcinoma: A Case Report of a Partial Response after a Third Reintroduction of Platinum Doublets

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Immune Reactivity and Pseudoprogression or Tumor Flare in a Serially Biopsied Neuroendocrine Patient Treated with the Epigenetic Agent RRx-001

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Partial Response in an RRx-001-Primed Patient with Refractory Small-Cell Lung Cancer after a Third Introduction of Platinum Doublets

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Flushing Out Carcinoid Syndrome: Beneficial Effect of the Anticancer Epigenetic Agent RRx-001 in a Patient with a Treatment-Refractory Neuroendocrine Tumor

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Analytical Techniques for Small Molecule Solid Phase Synthesis

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RRx-001, A novel dinitroazetidine radiosensitizer

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A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells

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RRx-001, an epigenetic-based radio- and chemosensitizer, has vascular normalizing effects on SCCVII and U87 tumors

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The immunomodulatory anticancer agent, RRx-001, induces an interferon response through epigenetic induction of viral mimicry

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From METS to malaria: RRx-001, a multi-faceted anticancer agent with activity in cerebral malaria

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