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ArticlesPeer ReviewedFull Text
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
Author / Creator:Lan, Jun ; Ge, Jiwan ; Yu, Jinfang ; Shan, Sisi ; Zhou, Huan ; Fan, Shilong ; Zhang, Qi ; Shi, Xuanling ; Wang, Qisheng ; Zhang, Linqi ; Wang, Xinquan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-05, Vol.581 (7807), p.215-220
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Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution
Author / Creator:Zhang, Shuyuan ; Qiao, Shuyuan ; Yu, Jinfang ; Zeng, Jianwei ; Shan, Sisi ; Tian, Long ; Lan, Jun ; Zhang, Linqi ; Wang, Xinquan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1607-1607, Article 1607
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Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry
Author / Creator:Ge, Jiwan ; Wang, Ruoke ; Ju, Bin ; Zhang, Qi ; Sun, Jing ; Chen, Peng ; Zhang, Senyan ; Tian, Yuling ; Shan, Sisi ; Cheng, Lin ; Zhou, Bing ; Song, Shuo ; Zhao, Juanjuan ; Wang, Haiyan ; Shi, Xuanling ; Ding, Qiang ; Liu, Lei ; Zhao, Jincun ; Zhang, Zheng ; Wang, Xinquan ; Zhang, Linqi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.250-250, Article 250
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Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2
Author / Creator:Zhang, Qi ; Ju, Bin ; Ge, Jiwan ; Chan, Jasper Fuk-Woo ; Cheng, Lin ; Wang, Ruoke ; Huang, Weijin ; Fang, Mengqi ; Chen, Peng ; Zhou, Bing ; Song, Shuo ; Shan, Sisi ; Yan, Baohua ; Zhang, Senyan ; Ge, Xiangyang ; Yu, Jiazhen ; Zhao, Juanjuan ; Wang, Haiyan ; Liu, Li ; Lv, Qining ; Fu, Lili ; Shi, Xuanling ; Yuen, Kwok Yung ; Liu, Lei ; Wang, Youchun ; Chen, Zhiwei ; Zhang, Linqi ; Wang, Xinquan ; Zhang, Zheng
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4210-12, Article 4210
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A potent and protective human neutralizing antibody targeting a novel vulnerable site of Epstein-Barr virus
Author / Creator:Zhu, Qian-Ying ; Shan, Sisi ; Yu, Jinfang ; Peng, Si-Ying ; Sun, Cong ; Zuo, Yanan ; Zhong, Lan-Yi ; Yan, Shu-Mei ; Zhang, Xiao ; Yang, Ziqing ; Peng, Yong-Jian ; Shi, Xuanling ; Cao, Su-Mei ; Wang, Xinquan ; Zeng, Mu-Sheng ; Zhang, Linqi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6624-6624, Article 6624
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Structural basis of α1A-adrenergic receptor activation and recognition by an extracellular nanobody
Author / Creator:Toyoda, Yosuke ; Zhu, Angqi ; Kong, Fang ; Shan, Sisi ; Zhao, Jiawei ; Wang, Nan ; Sun, Xiaoou ; Zhang, Linqi ; Yan, Chuangye ; Kobilka, Brian K. ; Liu, Xiangyu
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-06, Vol.14 (1), p.3655-3655, Article 3655
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Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses
Author / Creator:Li, Mingxi ; Ren, Yifei ; Aw, Zhen Qin ; Chen, Bo ; Yang, Ziqing ; Lei, Yuqing ; Cheng, Lin ; Liang, Qingtai ; Hong, Junxian ; Yang, Yiling ; Chen, Jing ; Wong, Yi Hao ; Wei, Jing ; Shan, Sisi ; Zhang, Senyan ; Ge, Jiwan ; Wang, Ruoke ; Dong, Jay Zengjun ; Chen, Yuxing ; Shi, Xuanling ; Zhang, Qi ; Zhang, Zheng ; Chu, Justin Jang Hann ; Wang, Xinquan ; Zhang, Linqi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-12, Vol.13 (1), p.7957-17, Article 7957
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Super broad and protective nanobodies against Sarbecoviruses including SARS-CoV-1 and the divergent SARS-CoV-2 subvariant KP.3.1.1
Author / Creator:Dong, Haodi ; Zhou, Runhong ; Chen, Jing ; Wei, Jing ; Wei, Zimeng ; Yang, Ziqing ; Zhu, Kun ; Yang, Yufan ; Yang, Qianqian ; Liu, Na ; Chen, Yuting ; Wu, Yuhan ; Liang, Yan ; Zeng, Yige ; Guo, Qile ; Li, Mingxi ; Shan, Sisi ; Wang, Han ; Niu, Mengyue ; Yunfei Zeng, Isabella ; Shi, Xuanling ; Zhang, Qi ; Wang, Xinquan ; Chen, Zhiwei ; Zhang, Linqi
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-11, Vol.20 (11), p.e1012625
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Newsletter articlesFull Text
WIPO PUBLISHES PATENT OF CHINA ACADEMY OF MACHINERY SCIENCE TECHNOLOGY ADVANCED MANUFACTURE TECHNOLOGY CENTER, ZHONGDE SHAN, SISI CHEN AND FENG LIU FOR "METHOD FOR PREPARING LONGITUDINALLY REINFORCED...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2014
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Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection
Author / Creator:Jia, Wenxu ; Channappanavar, Rudragouda ; Zhang, Chao ; Li, Mingxi ; Zhou, Haixia ; Zhang, Shuyuan ; Zhou, Panpan ; Xu, Jiuyang ; Shan, Sisi ; Shi, Xuanling ; Wang, Xinquan ; Zhao, Jincun ; Zhou, Dongming ; Perlman, Stanley ; Zhang, Linqi
Publisher:United States: Taylor & Francis
Journal title:Emerging microbes & infections, 2019-01, Vol.8 (1), p.760-772
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Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages
Author / Creator:Li, Xiaoman ; Pan, Yongbing ; Yin, Qiangling ; Wang, Zejun ; Shan, Sisi ; Zhang, Laixing ; Yu, Jinfang ; Qu, Yuanyuan ; Sun, Lina ; Gui, Fang ; Lu, Jia ; Jing, Zhaofei ; Wu, Wei ; Huang, Tao ; Shi, Xuanling ; Li, Jiandong ; Li, Xinguo ; Li, Dexin ; Wang, Shiwen ; Yang, Maojun ; Zhang, Linqi ; Duan, Kai ; Liang, Mifang ; Yang, Xiaoming ; Wang, Xinquan
Publisher:Singapore: Springer Nature Singapore
Journal title:Cell discovery, 2022-09, Vol.8 (1), p.87-15, Article 87
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SARS-CoV-2 hijacks neutralizing dimeric IgA for nasal infection and injury in Syrian hamsters1
Author / Creator:Zhou, Biao ; Zhou, Runhong ; Jasper Fuk-Woo Chan ; Zeng, Jianwei ; Zhang, Qi ; Yuan, Shuofeng ; Liu, Li ; Robinot, Rémy ; Shan, Sisi ; Liu, Na ; Ge, Jiwan ; Kwong, Hugo Yat-Hei ; Zhou, Dongyan ; Xu, Haoran ; Chris Chung-Sing Chan ; Poon, Vincent Kwok-Man ; Chu, Hin ; Yue, Ming ; Ka-Yi, Kwan ; Chun-Yin, Chan ; Chris Chun-Yiu Chan ; Kenn Ka-Heng Chik ; Du, Zhenglong ; Ka-Kit Au ; Huang, Haode ; Man, Hiu-On ; Cao, Jianli ; Li, Cun ; Wang, Ziyi ; Zhou, Jie ; Song, Youqiang ; Man-Lung Yeung ; Kelvin Kai-Wang To ; Ho, David D ; Chakrabarti, Lisa A ; Wang, Xinquan ; Zhang, Linqi ; Kwok-Yung, Yuen ; Chen, Zhiwei
Publisher:London: Taylor & Francis Ltd
Journal title:Emerging microbes & infections, 2023-12, Vol.12 (2), p.2245921
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The Health Impacts and Life Challenges Caused by the COVID-19 Pandemic on Hong Kong Chinese Women
Author / Creator:Hung, Maria Shuk Yu ; Chan, Liliane Chui King ; Liu, Sisi Pui Shan
Publisher:Switzerland: MDPI AG
Journal title:International journal of environmental research and public health, 2022-04, Vol.19 (9), p.5115
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The Psychological and Quality of Life Impacts on Women in Hong Kong during the COVID-19 Pandemic
Author / Creator:Hung, Maria Shuk Yu ; Lam, Stanley Kam Ki ; Chan, Liliane Chui King ; Liu, Sisi Pui Shan ; Chow, Meyrick Chum Ming
Publisher:Basel: MDPI AG
Journal title:International journal of environmental research and public health, 2021-06, Vol.18 (13), p.6734
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Human neutralizing antibodies elicited by SARS-CoV-2 infection
Author / Creator:Ju, Bin ; Zhang, Qi ; Ge, Jiwan ; Wang, Ruoke ; Sun, Jing ; Ge, Xiangyang ; Yu, Jiazhen ; Shan, Sisi ; Zhou, Bing ; Song, Shuo ; Tang, Xian ; Yu, Jinfang ; Lan, Jun ; Yuan, Jing ; Wang, Haiyan ; Zhao, Juanjuan ; Zhang, Shuye ; Wang, Youchun ; Shi, Xuanling ; Liu, Lei ; Zhao, Jincun ; Wang, Xinquan ; Zhang, Zheng ; Zhang, Linqi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-08, Vol.584 (7819), p.115-119
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Deep learning guided optimization of human antibody against SARS-CoV-2 variants with broad neutralization
Author / Creator:Shan, Sisi ; Luo, Shitong ; Yang, Ziqing ; Hong, Junxian ; Su, Yufeng ; Ding, Fan ; Fu, Lili ; Li, Chenyu ; Chen, Peng ; Ma, Jianzhu ; Shi, Xuanling ; Zhang, Qi ; Berger, Bonnie ; Zhang, Linqi ; Peng, Jian
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (11), p.1-9
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Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants
Author / Creator:Ju, Bin ; Zhang, Qi ; Wang, Ziyi ; Aw, Zhen Qin ; Chen, Peng ; Zhou, Bing ; Wang, Ruoke ; Ge, Xiangyang ; Lv, Qining ; Cheng, Lin ; Zhang, Rui ; Wong, Yi Hao ; Chen, Huixin ; Wang, Haiyan ; Shan, Sisi ; Liao, Xuejiao ; Shi, Xuanling ; Liu, Lei ; Chu, Justin Jang Hann ; Wang, Xinquan ; Zhang, Zheng ; Zhang, Linqi
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2023-04, Vol.24 (4), p.690-699
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A Highly Automated Mobile Laboratory for On-site Molecular Diagnostics in the COVID-19 Pandemic
Author / Creator:Xing, Wanli ; Wang, Jiadao ; Zhao, Chao ; Wang, Han ; Bai, Liang ; Pan, Liangbin ; Li, Hang ; Wang, Huili ; Zhang, Zhi ; Lu, Ying ; Chen, Xiang ; Shan, Sisi ; Wang, Dong ; Pan, Yifei ; Weng, Ding ; Zhou, Xinying ; Huang, Rudan ; He, Jianxing ; Jin, Ronghua ; Li, Weimin ; Shang, Hong ; Zhong, Nanshan ; Cheng, Jing
Publisher:England: Oxford University Press
Journal title:Clinical chemistry (Baltimore, Md.), 2021-03, Vol.67 (4), p.672-683
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Super broad and protective nanobodies against Sarbecoviruses including SARS-CoV-1 and the divergent SARS-CoV-2 subvariant KP.3.1.1
Author / Creator:Haodi Dong ; Runhong Zhou ; Jing Chen ; Jing Wei ; Zimeng Wei ; Ziqing Yang ; Kun Zhu ; Yufan Yang ; Qianqian Yang ; Na Liu ; Yuting Chen ; Yuhan Wu ; Yan Liang ; Yige Zeng ; Qile Guo ; Mingxi Li ; Sisi Shan ; Han Wang ; Mengyue Niu ; Isabella Yunfei Zeng ; Xuanling Shi ; Qi Zhang ; Xinquan Wang ; Zhiwei Chen ; Linqi Zhang
Publisher:Public Library of Science (PLoS)
Journal title:PLoS pathogens, 2024-11, Vol.20 (11), p.e1012625
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A Versatile High‐Throughput Single‐Cell Screening Platform for Profiling Antigen‐Specific Long‐Lived B Cells in Blood and Bone Marrow
Author / Creator:Zhao, Tian ; Lei, Yuqing ; Liu, Chang ; Zhang, Dong ; Li, Kaiyi ; Shan, Sisi ; Li, Chenyu ; Wei, Zimeng ; Yang, Yuhan ; Zhang, Ting ; Sun, Kai ; Sun, Haoran ; Zhang, Linqi ; Liu, Peng
Publisher:Germany
Journal title:Advanced science, 2025-04, p.e2414945
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Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

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Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution

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Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry

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Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2

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A potent and protective human neutralizing antibody targeting a novel vulnerable site of Epstein-Barr virus

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Structural basis of α1A-adrenergic receptor activation and recognition by an extracellular nanobody

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Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses

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Super broad and protective nanobodies against Sarbecoviruses including SARS-CoV-1 and the divergent SARS-CoV-2 subvariant KP.3.1.1

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WIPO PUBLISHES PATENT OF CHINA ACADEMY OF MACHINERY SCIENCE TECHNOLOGY ADVANCED MANUFACTURE TECHNOLOGY CENTER, ZHONGDE SHAN, SISI CHEN AND FENG LIU FOR "METHOD FOR PREPARING LONGITUDINALLY REINFORCED...

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Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection

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Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages

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SARS-CoV-2 hijacks neutralizing dimeric IgA for nasal infection and injury in Syrian hamsters1

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The Health Impacts and Life Challenges Caused by the COVID-19 Pandemic on Hong Kong Chinese Women

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The Psychological and Quality of Life Impacts on Women in Hong Kong during the COVID-19 Pandemic

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Human neutralizing antibodies elicited by SARS-CoV-2 infection

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Deep learning guided optimization of human antibody against SARS-CoV-2 variants with broad neutralization

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Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants

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A Highly Automated Mobile Laboratory for On-site Molecular Diagnostics in the COVID-19 Pandemic

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Super broad and protective nanobodies against Sarbecoviruses including SARS-CoV-1 and the divergent SARS-CoV-2 subvariant KP.3.1.1

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A Versatile High‐Throughput Single‐Cell Screening Platform for Profiling Antigen‐Specific Long‐Lived B Cells in Blood and Bone Marrow

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