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29 results for Sheahan,+Timothy+P.

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Sheahan, Timothy P
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: SAR-SOK, 2022, p.10363-10363
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Sheahan, Timothy P
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: SAV-SOP, 2021, p.10332-10332
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ArticlesPeer ReviewedFull Text
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
Author / Creator:Sheahan, Timothy P. ; Sims, Amy C. ; Leist, Sarah R. ; Schäfer, Alexandra ; Won, John ; Brown, Ariane J. ; Montgomery, Stephanie A. ; Hogg, Alison ; Babusis, Darius ; Clarke, Michael O. ; Spahn, Jamie E. ; Bauer, Laura ; Sellers, Scott ; Porter, Danielle ; Feng, Joy Y. ; Cihlar, Tomas ; Jordan, Robert ; Denison, Mark R. ; Baric, Ralph S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-01, Vol.11 (1), p.222-14, Article 222
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SARS-like WIV1-CoV poised for human emergence
Author / Creator:Menachery, Vineet D. ; Yount, Boyd L. ; Sims, Amy C. ; Debbink, Kari ; Agnihothram, Sudhakar S. ; Gralinski, Lisa E. ; Graham, Rachel L. ; Scobey, Trevor ; Plante, Jessica A. ; Royal, Scott R. ; Swanstrom, Jesica ; Sheahan, Timothy P. ; Pickles, Raymond J. ; Corti, Davide ; Randell, Scott H. ; Lanzavecchia, Antonio ; Marasco, Wayne A. ; Baric, Ralph S.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (11), p.3048-3053
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ArticlesPeer ReviewedFull Text
Hypergraph models of biological networks to identify genes critical to pathogenic viral response
Author / Creator:Feng, Song ; Heath, Emily ; Jefferson, Brett ; Joslyn, Cliff ; Kvinge, Henry ; Mitchell, Hugh D. ; Praggastis, Brenda ; Eisfeld, Amie J. ; Sims, Amy C. ; Thackray, Larissa B. ; Fan, Shufang ; Walters, Kevin B. ; Halfmann, Peter J. ; Westhoff-Smith, Danielle ; Tan, Qing ; Menachery, Vineet D. ; Sheahan, Timothy P. ; Cockrell, Adam S. ; Kocher, Jacob F. ; Stratton, Kelly G. ; Heller, Natalie C. ; Bramer, Lisa M. ; Diamond, Michael S. ; Baric, Ralph S. ; Waters, Katrina M. ; Kawaoka, Yoshihiro ; McDermott, Jason E. ; Purvine, Emilie
Publisher:London: BioMed Central
Journal title:BMC bioinformatics, 2021-05, Vol.22 (1), p.1-287, Article 287
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ArticlesPeer ReviewedFull Text
Modeling hepatitis C virus infection using human induced pluripotent stem cells
Author / Creator:Schwartz, Robert E ; Trehan, Kartik ; Andrus, Linda ; Sheahan, Timothy P ; Ploss, Alexander ; Duncan, Stephen A ; Rice, Charles M ; Bhatia, Sangeeta N
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2544-2548
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ArticlesPeer ReviewedFull Text
Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis
Author / Creator:Leist, Sarah R. ; Jensen, Kara L. ; Baric, Ralph S. ; Sheahan, Timothy P.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-07, Vol.14 (7), p.e0220126-e0220126
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A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans
Author / Creator:Hanafin, Patrick O. ; Jermain, Brian ; Hickey, Anthony J. ; Kabanov, Alexander V. ; Kashuba, Angela DM ; Sheahan, Timothy P. ; Rao, Gauri G.
Publisher:United States: John Wiley & Sons, Inc
Journal title:CPT: pharmacometrics and systems pharmacology, 2021-02, Vol.10 (2), p.89-99
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Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures
Author / Creator:Dinnon, Kenneth H. ; Leist, Sarah R. ; Schäfer, Alexandra ; Edwards, Caitlin E. ; Martinez, David R. ; Montgomery, Stephanie A. ; West, Ande ; Yount, Boyd L. ; Hou, Yixuan J. ; Adams, Lily E. ; Gully, Kendra L. ; Brown, Ariane J. ; Huang, Emily ; Bryant, Matthew D. ; Choong, Ingrid C. ; Glenn, Jeffrey S. ; Gralinski, Lisa E. ; Sheahan, Timothy P. ; Baric, Ralph S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-02, Vol.590 (7844), p.E22-E22
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ArticlesPeer ReviewedFull Text
Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion
Author / Creator:Lindesmith, Lisa C. ; Mallory, Michael L. ; Debbink, Kari ; Donaldson, Eric F. ; Brewer-Jensen, Paul D. ; Swann, Excel W. ; Sheahan, Timothy P. ; Graham, Rachel L. ; Beltramello, Martina ; Corti, Davide ; Lanzavecchia, Antonio ; Baric, Ralph S.
Publisher:United States: American Society for Microbiology
Journal title:mSphere, 2018-01, Vol.3 (1)
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ArticlesPeer ReviewedFull Text
Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East respiratory syndrome coronavirus disease severity
Author / Creator:Sims, Amy C. ; Schäfer, Alexandra ; Okuda, Kenichi ; Leist, Sarah R. ; Kocher, Jacob F. ; Cockrell, Adam S. ; Hawkins, Padraig E. ; Furusho, Minako ; Jensen, Kara L. ; Kyle, Jennifer E. ; Burnum-Johnson, Kristin E. ; Stratton, Kelly G. ; Lamar, Natalie C. ; Niccora, Carrie D. ; Weitz, Karl K. ; Smith, Richard D. ; Metz, Thomas O. ; Waters, Katrina M. ; Boucher, Richard C. ; Montgomery, Stephanie A. ; Baric, Ralph S. ; Sheahan, Timothy P.
Publisher:United States: American Society for Microbiology
Journal title:mSphere, 2025-02, Vol.10 (2), p.e0095124
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ArticlesPeer ReviewedFull Text
A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures
Author / Creator:Dinnon, Kenneth H. ; Leist, Sarah R. ; Schäfer, Alexandra ; Edwards, Caitlin E. ; Martinez, David R. ; Montgomery, Stephanie A. ; West, Ande ; Yount, Boyd L. ; Hou, Yixuan J. ; Adams, Lily E. ; Gully, Kendra L. ; Brown, Ariane J. ; Huang, Emily ; Bryant, Matthew D. ; Choong, Ingrid C. ; Glenn, Jeffrey S. ; Gralinski, Lisa E. ; Sheahan, Timothy P. ; Baric, Ralph S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-10, Vol.586 (7830), p.560-566
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ArticlesPeer ReviewedFull Text
Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy
Author / Creator:Yamin, Rachel ; Jones, Andrew T. ; Hoffmann, Hans-Heinrich ; Schäfer, Alexandra ; Kao, Kevin S. ; Francis, Rebecca L. ; Sheahan, Timothy P. ; Baric, Ralph S. ; Rice, Charles M. ; Ravetch, Jeffrey V. ; Bournazos, Stylianos
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-11, Vol.599 (7885), p.465-470
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Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome
Author / Creator:Zhang, Kaiming ; Zheludev, Ivan N. ; Hagey, Rachel J. ; Haslecker, Raphael ; Hou, Yixuan J. ; Kretsch, Rachael ; Pintilie, Grigore D. ; Rangan, Ramya ; Kladwang, Wipapat ; Li, Shanshan ; Wu, Marie Teng-Pei ; Pham, Edward A. ; Bernardin-Souibgui, Claire ; Baric, Ralph S. ; Sheahan, Timothy P. ; D’Souza, Victoria ; Glenn, Jeffrey S. ; Chiu, Wah ; Das, Rhiju
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2021-09, Vol.28 (9), p.747-754
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Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2
Author / Creator:Hagey, Rachel J. ; Elazar, Menashe ; Pham, Edward A. ; Tian, Siqi ; Ben-Avi, Lily ; Bernardin-Souibgui, Claire ; Yee, Matthew F. ; Moreira, Fernando R. ; Rabinovitch, Meirav Vilan ; Meganck, Rita M. ; Fram, Benjamin ; Beck, Aimee ; Gibson, Scott A. ; Lam, Grace ; Devera, Josephine ; Kladwang, Wipapat ; Nguyen, Khanh ; Xiong, Anming ; Schaffert, Steven ; Avisar, Talia ; Liu, Ping ; Rustagi, Arjun ; Fichtenbaum, Carl J. ; Pang, Phillip S. ; Khatri, Purvesh ; Tseng, Chien-Te ; Taubenberger, Jeffery K. ; Blish, Catherine A. ; Hurst, Brett L. ; Sheahan, Timothy P. ; Das, Rhiju ; Glenn, Jeffrey S.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2022-09, Vol.28 (9), p.1944-1955
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Is regulation preventing the development of therapeutics that may prevent future coronavirus pandemics?
Author / Creator:Sheahan, Timothy P ; Baric, Ralph S
Publisher:England: Future Medicine Ltd
Journal title:Future virology, 2018-03, Vol.13 (3), p.143-146
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Multi-Modal Imaging with a Toolbox of Influenza A Reporter Viruses
Author / Creator:Tran, Vy ; Poole, Daniel S ; Jeffery, Justin J ; Sheahan, Timothy P ; Creech, Donald ; Yevtodiyenko, Aleksey ; Peat, Andrew J ; Francis, Kevin P ; You, Shihyun ; Mehle, Andrew
Publisher:Switzerland: MDPI
Journal title:Viruses, 2015-10, Vol.7 (10), p.5319-5327
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A compendium of multi-omics data illuminating host responses to lethal human virus infections
Author / Creator:Eisfeld, Amie J. ; Anderson, Lindsey N. ; Fan, Shufang ; Walters, Kevin B. ; Halfmann, Peter J. ; Westhoff Smith, Danielle ; Thackray, Larissa B. ; Tan, Qing ; Sims, Amy C. ; Menachery, Vineet D. ; Schäfer, Alexandra ; Sheahan, Timothy P. ; Cockrell, Adam S. ; Stratton, Kelly G. ; Webb-Robertson, Bobbie-Jo M. ; Kyle, Jennifer E. ; Burnum-Johnson, Kristin E. ; Kim, Young-Mo ; Nicora, Carrie D. ; Peralta, Zuleyma ; N’jai, Alhaji U. ; Sahr, Foday ; van Bakel, Harm ; Diamond, Michael S. ; Baric, Ralph S. ; Metz, Thomas O. ; Smith, Richard D. ; Kawaoka, Yoshihiro ; Waters, Katrina M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific data, 2024-04, Vol.11 (1), p.328-328, Article 328
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Multi-Modal Imaging with a Toolbox of Influenza AReporter Viruses
Author / Creator:Tran, Vy ; Poole, Daniel ; Jeffery, Justin ; Sheahan, Timothy ; Creech, Donald ; Yevtodiyenko, Aleksey ; Peat, Andrew ; Francis, Kevin ; You, Shihyun ; Mehle, Andrew
Publisher:Basel: MDPI AG
Journal title:Viruses, 2015-10, Vol.7 (10), p.5319-5327
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Preparing for Tomorrow's Pandemics, Today
Publisher:Sigma Xi, The Scientific Research Society
Journal title:American scientist, 2021-09, Vol.109 (5), p.260
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Sheahan, Timothy P

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Sheahan, Timothy P

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Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

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SARS-like WIV1-CoV poised for human emergence

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Hypergraph models of biological networks to identify genes critical to pathogenic viral response

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Modeling hepatitis C virus infection using human induced pluripotent stem cells

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Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis

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A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans

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Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

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Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion

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Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East respiratory syndrome coronavirus disease severity

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A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

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Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy

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Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome

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Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2

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Is regulation preventing the development of therapeutics that may prevent future coronavirus pandemics?

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Multi-Modal Imaging with a Toolbox of Influenza A Reporter Viruses

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A compendium of multi-omics data illuminating host responses to lethal human virus infections

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Multi-Modal Imaging with a Toolbox of Influenza AReporter Viruses

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Preparing for Tomorrow's Pandemics, Today

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