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Reference EntriesFull Text
Shen, Che-Kun James
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: SAR-SOK, 2022, p.10379-10379
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Reference EntriesFull Text
Shen, Che-Kun James
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: SAV-SOP, 2021, p.10348-10348
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ArticlesPeer ReviewedFull Text
RNA Modifications and RNA Metabolism in Neurological Disease Pathogenesis
Author / Creator:Chatterjee, Biswanath ; Shen, Che-Kun James ; Majumder, Pritha
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-11, Vol.22 (21), p.11870
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Newsletter articlesFull Text
Shen Che-Kun James, Chou Yu-Chi and Academia Sinica Apply for Patent on Methods and Compositions for Treating Beta-Thalassemia and Sickle Cell Disease
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2014
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ArticlesPeer ReviewedFull Text
TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh
Author / Creator:Zhao, Limin ; Ke, Hao ; Xu, Haibo ; Wang, Guo-Dong ; Zhang, Honglei ; Zou, Li ; Xiang, Shu ; Li, Mengyuan ; Peng, Li ; Zhou, Mingfang ; Li, Lingling ; Ao, Lei ; Yang, Qin ; Shen, Che-Kun James ; Yi, Ping ; Wang, Lu ; Jiao, Baowei
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-01, Vol.11 (1), p.341-341, Article 341
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ArticlesPeer ReviewedFull Text
Human Mesenchymal Stem Cells Prolong Survival and Ameliorate Motor Deficit through Trophic Support in Huntington's Disease Mouse Models
Author / Creator:Lin, Yuan-Ta ; Chern, Yijuang ; Shen, Che-Kun James ; Wen, Hsin-Lan ; Chang, Ya-Chin ; Li, Hung ; Cheng, Tzu-Hao ; Hsieh-Li, Hsiu Mei
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-08, Vol.6 (8), p.e22924
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ArticlesPeer ReviewedFull Text
Therapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS
Author / Creator:Chang, Cheng-Fu ; Lee, Yi-Chao ; Lee, Kuen-Haur ; Lin, Hui-Ching ; Chen, Chia-Ling ; Shen, Che-Kun James ; Huang, Chi-Chen
Publisher:England: BioMed Central Ltd
Journal title:Journal of biomedical science, 2016-10, Vol.23 (1), p.72-72, Article 72
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ArticlesPeer ReviewedFull Text
Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Author / Creator:Lee, Yi-Chao ; Huang, Wan-Chen ; Lin, Jiann-Her ; Kao, Tzu-Jen ; Lin, Hui-Ching ; Lee, Kuen-Haur ; Lin, Hsin-Chuan ; Shen, Che-Kun James ; Chang, Wen-Chang ; Huang, Chi-Chen
Publisher:England: BioMed Central Ltd
Journal title:Journal of biomedical science, 2018-11, Vol.25 (1), p.76-76, Article 76
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ArticlesPeer ReviewedFull Text
A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis
Author / Creator:Hung, Chun-Hao ; Lee, Tung-Liang ; Huang, Anna Yu-Szu ; Yang, Kang-Chung ; Shyu, Yu-Chiau ; Wen, Shau-Ching ; Lu, Mu-Jie ; Yuan, Shinsheng ; Shen, Che-Kun James
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2021-07, Vol.22 (15), p.8024
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ArticlesPeer ReviewedFull Text
Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43
Author / Creator:Wang, I-Fang ; Guo, Bo-Shen ; Liu, Yu-Chih ; Wu, Cheng-Chun ; Yang, Chun-Hung ; Tsai, Kuen-Jer ; Shen, Che-Kun James
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (37), p.15024-15029
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ArticlesPeer ReviewedFull Text
Phosphorylation-Dependent SUMOylation of the Transcription Factor NF-E2
Author / Creator:Su, Yee-Fun ; Shyu, Yu-Chiau ; Shen, Che-Kun James ; Hwang, Jaulang
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-09, Vol.7 (9), p.e44608-e44608
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ArticlesPeer ReviewedFull Text
Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP
Author / Creator:Majumder, Pritha ; Chu, Jen-Fei ; Chatterjee, Biswanath ; Swamy, Krishna B. S. ; Shen, Che-Kun James
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2016-11, Vol.132 (5), p.721-738
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ArticlesPeer ReviewedFull Text
A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568
Author / Creator:Yang, Peng ; Wang, Yixuan ; Hoang, Don ; Tinkham, Matthew ; Patel, Anamika ; Sun, Ming-An ; Wolf, Gernot ; Baker, Mairead ; Chien, Huan-Chieh ; Lai, Kuan-Yu Nick ; Cheng, Xiaodong ; Shen, Che-Kun James ; Macfarlan, Todd S.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-05, Vol.356 (6339), p.757-760
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ArticlesPeer ReviewedFull Text
Targeted Disruption in Mice of a Neural Stem Cell-Maintaining, KRAB-Zn Finger-Encoding Gene That Has Rapidly Evolved in the Human Lineage
Author / Creator:Chien, Huan-Chieh ; Wang, Hurng-Yi ; Su, Yi-Ning ; Lai, Kuan-Yu ; Lu, Li-Chen ; Chen, Pau-Chung ; Tsai, Shih-Feng ; Wu, Chung-I ; Hsieh, Wu-Shiun ; Shen, Che-Kun James
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-10, Vol.7 (10), p.e47481-e47481
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ArticlesPeer ReviewedFull Text
Molecular switch of the dendrite-to-spine transport of TDP-43/FMRP-bound neuronal mRNAs and its impairment in ASD
Author / Creator:Majumder, Pritha ; Chatterjee, Biswanath ; Akter, Khadiza ; Ahsan, Asmar ; Tan, Su Jie ; Huang, Chi-Chen ; Chu, Jen-Fei ; Shen, Che-Kun James
Publisher:England: BioMed Central
Journal title:Cellular & molecular biology letters, 2025-01, Vol.30 (1), p.6-37, Article 6
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ArticlesPeer ReviewedFull Text
A robust TDP-43 knock-in mouse model of ALS
Author / Creator:Huang, Shih-Ling ; Wu, Lien-Szu ; Lee, Min ; Chang, Chin-Wen ; Cheng, Wei-Cheng ; Fang, Yu-Sheng ; Chen, Yun-Ru ; Cheng, Pei-Lin ; Shen, Che-Kun James
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2020-01, Vol.8 (1), p.3-3, Article 3
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ArticlesPeer ReviewedFull Text
TDP-43 regulates the mammalian spinogenesis through translational repression of Rac1
Author / Creator:Majumder, Pritha ; Chen, Yi-Ting ; Bose, Jayarama Krishnan ; Wu, Cheng-Chun ; Cheng, Wei-Cheng ; Cheng, Sin-Jhong ; Fang, Yen-Hsin ; Chen, Ying-Ling ; Tsai, Kuen-Jer ; Lien, Cheng-Chang ; Shen, Che-Kun James
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Acta neuropathologica, 2012-08, Vol.124 (2), p.231-245
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ArticlesPeer ReviewedFull Text
JNK-mediated turnover and stabilization of the transcription factor p45/NF-E2 during differentiation of murine erythroleukemia cells
Author / Creator:Lee, Tung-Liang ; Shyu, Yu-Chiau ; Hsu, Pang-Hung ; Chang, Chiung-Wen ; Wen, Shau-Ching ; Hsiao, Wei-Yuan ; Tsai, Ming-Daw ; Shen, Che-Kun James
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (1), p.52-57
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ArticlesPeer ReviewedFull Text
G-CSF-mobilized Bone Marrow Mesenchymal Stem Cells Replenish Neural Lineages in Alzheimer’s Disease Mice via CXCR4/SDF-1 Chemotaxis
Author / Creator:Wu, Cheng-Chun ; Wang, I-Fang ; Chiang, Po-Min ; Wang, Liang-Chao ; Shen, Che-Kun James ; Tsai, Kuen-Jer
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2017-10, Vol.54 (8), p.6198-6212
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ArticlesPeer ReviewedFull Text
Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
Author / Creator:Chiang, Chien-Hao ; Grauffel, Cédric ; Wu, Lien-Szu ; Kuo, Pan-Hsien ; Doudeva, Lyudmila G. ; Lim, Carmay ; Shen, Che-Kun James ; Yuan, Hanna S.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-02, Vol.6 (1), p.21581-21581, Article 21581
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Shen, Che-Kun James

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Shen, Che-Kun James

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RNA Modifications and RNA Metabolism in Neurological Disease Pathogenesis

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Shen Che-Kun James, Chou Yu-Chi and Academia Sinica Apply for Patent on Methods and Compositions for Treating Beta-Thalassemia and Sickle Cell Disease

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TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh

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Human Mesenchymal Stem Cells Prolong Survival and Ameliorate Motor Deficit through Trophic Support in Huntington's Disease Mouse Models

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Therapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS

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Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology

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A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis

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Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

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Phosphorylation-Dependent SUMOylation of the Transcription Factor NF-E2

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Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP

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A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568

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Targeted Disruption in Mice of a Neural Stem Cell-Maintaining, KRAB-Zn Finger-Encoding Gene That Has Rapidly Evolved in the Human Lineage

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Molecular switch of the dendrite-to-spine transport of TDP-43/FMRP-bound neuronal mRNAs and its impairment in ASD

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A robust TDP-43 knock-in mouse model of ALS

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TDP-43 regulates the mammalian spinogenesis through translational repression of Rac1

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JNK-mediated turnover and stabilization of the transcription factor p45/NF-E2 during differentiation of murine erythroleukemia cells

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G-CSF-mobilized Bone Marrow Mesenchymal Stem Cells Replenish Neural Lineages in Alzheimer’s Disease Mice via CXCR4/SDF-1 Chemotaxis

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Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation

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