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Measuring Drug Occupancy in the Absence of a Reference Region: The Lassen Plot Re-Visited
Author / Creator:Cunningham, Vincent J ; Rabiner, Eugenii A ; Slifstein, Mark ; Laruelle, Marc ; Gunn, Roger N
Publisher:London, England: SAGE Publications
Journal title:Journal of cerebral blood flow and metabolism, 2010-01, Vol.30 (1), p.46-50
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Impact of D2 Receptor Internalization on Binding Affinity of Neuroimaging Radiotracers
Author / Creator:Guo, Ningning ; Guo, Wen ; Kralikova, Michaela ; Jiang, Man ; Schieren, Ira ; Narendran, Raj ; Slifstein, Mark ; Abi-Dargham, Anissa ; Laruelle, Marc ; Javitch, Jonathan A ; Rayport, Stephen
Publisher:Cham: Springer International Publishing
Journal title:Neuropsychopharmacology (New York, N.Y.), 2010-02, Vol.35 (3), p.806-817
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Deep rTMS of the insula and prefrontal cortex in smokers with schizophrenia: Proof-of-concept study
Author / Creator:Moeller, Scott J ; Gil, Roberto ; Weinstein, Jodi J ; Baumvoll, Topaz ; Wengler, Kenneth ; Fallon, Natalka ; Van Snellenberg, Jared X ; Abeykoon, Sameera ; Perlman, Greg ; Williams, John ; Manu, Lucian ; Slifstein, Mark ; Cassidy, Clifford M ; Martinez, Diana M ; Abi-Dargham, Anissa
Publisher:United States: Nature Publishing Group
Journal title:NPJ schizophrenia, 2022-02, Vol.8 (1), p.6-9
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[11C]NNC 112 Selectivity for Dopamine D1 and Serotonin 5-HT2A Receptors: A PET Study in Healthy Human Subjects
Author / Creator:Slifstein, Mark ; Kegeles, Lawrence S ; Gonzales, Robyn ; Frankle, William G ; Xu, Xiaoyan ; Laruelle, Marc ; Abi-Dargham, Anissa
Publisher:London, England: SAGE Publications
Journal title:Journal of cerebral blood flow and metabolism, 2007-10, Vol.27 (10), p.1733-1741
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In Vivo DA D1 Receptor Selectivity of NNC 112 and SCH 23390
Author / Creator:Ekelund, Jesper ; Slifstein, Mark ; Narendran, Raj ; Guillin, Olivier ; Belani, Hemant ; Guo, Ning-Ning ; Hwang, Yuying ; Hwang, Dah-Ren ; Abi-Dargham, Anissa ; Laruelle, Marc
Publisher:New York: Springer Nature B.V
Journal title:Molecular imaging and biology, 2007-05, Vol.9 (3), p.117, Article 117
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Biodistribution and Radiation Dosimetry of the Glycine Transporter-1 Ligand 11C-GSK931145 Determined from Primate and Human Whole-Body PET
Author / Creator:Bullich, Santiago ; Slifstein, Mark ; Passchier, Jan ; Murthy, N. Venkatesha ; Kegeles, Lawrence S. ; Kim, Jong-Hoon ; Xu, Xiaoyan ; Gunn, Roger N. ; Herance, Raul ; Gispert, Juan Domingo ; Gutiérrez, Antonio ; Farré, Magí ; Laruelle, Marc ; Catafau, Ana M.
Publisher:New York: Springer-Verlag
Journal title:Molecular imaging and biology, 2011-08, Vol.13 (4), p.776-784
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43.4 THE ROLE OF MOLECULAR IMAGING IN GUIDING DRUG DEVELOPMENT
Author / Creator:Abi-Dargham, Anissa ; Kegeles, Lawrence ; Slifstein, Mark
Publisher:US: Oxford University Press
Journal title:Schizophrenia bulletin, 2018-04, Vol.44 (suppl_1), p.S71-S71
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When reversible ligands do not reverse, and other modelers' dilemmas
Author / Creator:Slifstein, Mark
Publisher:United States: Society of Nuclear Medicine
Journal title:The Journal of nuclear medicine (1978), 2010-07, Vol.51 (7), p.1005-1008
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A positron emission tomography occupancy study of brexpiprazole at dopamine D2 and D3 and serotonin 5-HT1A and 5-HT2A receptors, and serotonin reuptake transporters in subjects with schizophrenia
Author / Creator:Girgis, Ragy R. ; Forbes, Andy ; Abi-Dargham, Anissa ; Slifstein, Mark
Publisher:New York: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2020-04, Vol.45 (5), p.786-792
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When Reversible Ligands Do Not Reverse, and Other Modelers' Dilemmas: FIGURE 1.
Author / Creator:Slifstein, Mark
Journal title:Journal of Nuclear Medicine, 2010-07, Vol.51 (7), p.1005-1008
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Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [11C]-(+)-PHNO
Author / Creator:Girgis, Ragy R. ; Slifstein, Mark ; D’Souza, Deepak ; Lee, Yih ; Periclou, Antonia ; Ghahramani, Parviz ; Laszlovszky, István ; Durgam, Suresh ; Adham, Nika ; Nabulsi, Nabeel ; Huang, Yiyun ; Carson, Richard E. ; Kiss, Béla ; Kapás, Margit ; Abi-Dargham, Anissa ; Rakhit, Ashok
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Psychopharmacology, 2016-10, Vol.233 (19-20), p.3503-3512
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Imaging synaptic dopamine availability in individuals at clinical high-risk for psychosis: a [11C]-(+)-PHNO PET with methylphenidate challenge study
Author / Creator:Girgis, Ragy R. ; Slifstein, Mark ; Brucato, Gary ; Kegeles, Lawrence S. ; Colibazzi, Tiziano ; Lieberman, Jeffrey A. ; Abi-Dargham, Anissa
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2021-06, Vol.26 (6), p.2504-2513
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Kappa-opioid receptors, dynorphin, and cocaine addiction: a positron emission tomography study
Author / Creator:Martinez, Diana ; Slifstein, Mark ; Matuskey, David ; Nabulsi, Nabeel ; Zheng, Ming-Qiang ; Lin, Shu-fei ; Ropchan, Jim ; Urban, Nina ; Grassetti, Alexander ; Chang, Dinnisa ; Salling, Michael ; Foltin, Richard ; Carson, Richard E. ; Huang, Yiyun
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2019-09, Vol.44 (10), p.1720-1727
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Deficits in striatal dopamine release in cannabis dependence
Author / Creator:van de Giessen, E ; Weinstein, J J ; Cassidy, C M ; Haney, M ; Dong, Z ; Ghazzaoui, R ; Ojeil, N ; Kegeles, L S ; Xu, X ; Vadhan, N P ; Volkow, N D ; Slifstein, M ; Abi-Dargham, A
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2017-01, Vol.22 (1), p.68-75
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Revisiting an old issue: the discrepancy between tissue ratio-derived binding parameters and kinetic modeling-derived parameters after a bolus of the serotonin transporter radioligand 123I-ADAM
Author / Creator:Slifstein, Mark
Publisher:United States
Journal title:The Journal of nuclear medicine (1978), 2008-02, Vol.49 (2), p.176-178
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Revisiting an Old Issue: The Discrepancy Between Tissue Ratio–Derived Binding Parameters and Kinetic Modeling–Derived Parameters After a Bolus of the Serotonin Transporter Radioligand 123 I-ADAM
Author / Creator:Slifstein, Mark
Journal title:Journal of Nuclear Medicine, 2008-02, Vol.49 (2), p.176-178
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Revisiting an Old Issue: The Discrepancy Between Tissue Ratio-Derived Binding Parameters and Kinetic Modeling-Derived Parameters After a Bolus of the Serotonin Transporter Radioligand ^sup 123^I-ADAM
Author / Creator:Slifstein, Mark
Publisher:New York: Society of Nuclear Medicine
Journal title:The Journal of nuclear medicine (1978), 2008-02, Vol.49 (2), p.176
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Serotonin transporter availability in physically aggressive personality disordered patients: associations with trait and state aggression, and response to fluoxetine
Author / Creator:Rosell, Daniel R. ; Slifstein, Mark ; Thompson, Judy ; Xu, Xiaoyan ; Perez-Rodriguez, M. Mercedes ; McClure, Margaret M. ; Hazlett, Erin A. ; New, Antonia S. ; Nabulsi, Nabeel ; Huang, Yiyun ; Carson, Richard E. ; Siever, Larry S. ; Abi-Dargham, Anissa ; Koenigsberg, Harold W.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Psychopharmacology, 2023-02, Vol.240 (2), p.361-371
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Investigation of Cortical Glutamate–Glutamine and γ-Aminobutyric Acid in Obsessive–Compulsive Disorder by Proton Magnetic Resonance Spectroscopy
Author / Creator:Simpson, Helen B ; Shungu, Dikoma C ; Bender, James ; Mao, Xiangling ; Xu, Xiaoyan ; Slifstein, Mark ; Kegeles, Lawrence S
Publisher:Basingstoke: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2012-11, Vol.37 (12), p.2684-2692
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Dopamine D1R Receptor Stimulation as a Mechanistic Pro-cognitive Target for Schizophrenia
Author / Creator:Abi-Dargham, Anissa ; Javitch, Jonathan A ; Slifstein, Mark ; Anticevic, Alan ; Calkins, Monica E ; Cho, Youngsun T ; Fonteneau, Clara ; Gil, Roberto ; Girgis, Ragy ; Gur, Raquel E ; Gur, Ruben C ; Grinband, Jack ; Kantrowitz, Joshua ; Kohler, Christian ; Krystal, John ; Murray, John ; Ranganathan, Mohini ; Santamauro, Nicole ; Van Snellenberg, Jared ; Tamayo, Zailyn ; Wolf, Daniel ; Gray, David ; Lieberman, Jeffrey
Publisher:US: Oxford University Press
Journal title:Schizophrenia bulletin, 2022-01, Vol.48 (1), p.199-210
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Measuring Drug Occupancy in the Absence of a Reference Region: The Lassen Plot Re-Visited

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Impact of D2 Receptor Internalization on Binding Affinity of Neuroimaging Radiotracers

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Deep rTMS of the insula and prefrontal cortex in smokers with schizophrenia: Proof-of-concept study

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[11C]NNC 112 Selectivity for Dopamine D1 and Serotonin 5-HT2A Receptors: A PET Study in Healthy Human Subjects

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In Vivo DA D1 Receptor Selectivity of NNC 112 and SCH 23390

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Biodistribution and Radiation Dosimetry of the Glycine Transporter-1 Ligand 11C-GSK931145 Determined from Primate and Human Whole-Body PET

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43.4 THE ROLE OF MOLECULAR IMAGING IN GUIDING DRUG DEVELOPMENT

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When reversible ligands do not reverse, and other modelers' dilemmas

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A positron emission tomography occupancy study of brexpiprazole at dopamine D2 and D3 and serotonin 5-HT1A and 5-HT2A receptors, and serotonin reuptake transporters in subjects with schizophrenia

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When Reversible Ligands Do Not Reverse, and Other Modelers' Dilemmas: FIGURE 1.

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Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [11C]-(+)-PHNO

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Imaging synaptic dopamine availability in individuals at clinical high-risk for psychosis: a [11C]-(+)-PHNO PET with methylphenidate challenge study

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Kappa-opioid receptors, dynorphin, and cocaine addiction: a positron emission tomography study

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Deficits in striatal dopamine release in cannabis dependence

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Revisiting an old issue: the discrepancy between tissue ratio-derived binding parameters and kinetic modeling-derived parameters after a bolus of the serotonin transporter radioligand 123I-ADAM

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Revisiting an Old Issue: The Discrepancy Between Tissue Ratio–Derived Binding Parameters and Kinetic Modeling–Derived Parameters After a Bolus of the Serotonin Transporter Radioligand 123 I-ADAM

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Revisiting an Old Issue: The Discrepancy Between Tissue Ratio-Derived Binding Parameters and Kinetic Modeling-Derived Parameters After a Bolus of the Serotonin Transporter Radioligand ^sup 123^I-ADAM

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Serotonin transporter availability in physically aggressive personality disordered patients: associations with trait and state aggression, and response to fluoxetine

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Investigation of Cortical Glutamate–Glutamine and γ-Aminobutyric Acid in Obsessive–Compulsive Disorder by Proton Magnetic Resonance Spectroscopy

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Dopamine D1R Receptor Stimulation as a Mechanistic Pro-cognitive Target for Schizophrenia

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