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Newsletter articlesFull Text
Type 2 Diabetes; Type 2 diabetes: Understanding regulation of sugar levels for better treatment
Publisher:Atlanta: NewsRx
Journal title:Biotech Week, 2015, p.260
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ArticlesPeer ReviewedFull Text
PPAR control of metabolism and cardiovascular functions
Author / Creator:Montaigne, David ; Butruille, Laura ; Staels, Bart
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews cardiology, 2021-12, Vol.18 (12), p.809-823
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ArticlesPeer ReviewedFull Text
Hepatic sexual dimorphism — implications for non-alcoholic fatty liver disease
Author / Creator:Lefebvre, Philippe ; Staels, Bart
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Endocrinology, 2021-11, Vol.17 (11), p.662-670
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ArticlesPeer ReviewedFull Text
Cardiovascular Protection by Sodium Glucose Cotransporter 2 Inhibitors: Potential Mechanisms
Author / Creator:Staels, Bart, PhD
Publisher:United States: Elsevier Inc
Journal title:The American journal of cardiology, 2017-07, Vol.120 (1), p.S28-S36
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ArticlesPeer ReviewedFull Text
Distinct but complementary contributions of PPAR isotypes to energy homeostasis
Author / Creator:Dubois, Vanessa ; Eeckhoute, Jérôme ; Lefebvre, Philippe ; Staels, Bart
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-04, Vol.127 (4), p.1202-1214
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ArticlesPeer ReviewedFull Text
When the Clock stops ticking, metabolic syndrome explodes
Author / Creator:Staels, Bart
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2006-01, Vol.12 (1), p.54-55
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ArticlesPeer ReviewedFull Text
Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma
Author / Creator:Guillaumond, Fabienne ; Bidaut, Ghislain ; Ouaissi, Mehdi ; Servais, Stéphane ; Gouirand, Victoire ; Olivares, Orianne ; Lac, Sophie ; Borge, Laurence ; Roques, Julie ; Gayet, Odile ; Pinault, Michelle ; Guimaraes, Cyrille ; Nigri, Jérémy ; Loncle, Céline ; Lavaut, Marie-Noëlle ; Garcia, Stéphane ; Tailleux, Anne ; Staels, Bart ; Calvo, Ezequiel ; Tomasini, Richard ; Iovanna, Juan Lucio ; Vasseur, Sophie
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (8), p.2473-2478
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ArticlesPeer ReviewedFull Text
Understanding lipid metabolism through hepatic steat-omics
Author / Creator:Haas, Joel T. ; Staels, Bart
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Endocrinology, 2019-06, Vol.15 (6), p.321-322
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ArticlesPeer ReviewedFull Text
The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids
Author / Creator:Ducastel, Sarah ; Touche, Véronique ; Trabelsi, Mohamed-Sami ; Boulinguiez, Alexis ; Butruille, Laura ; Nawrot, Margaux ; Peschard, Simon ; Chávez-Talavera, Oscar ; Dorchies, Emilie ; Vallez, Emmanuelle ; Annicotte, Jean-Sébastien ; Lancel, Steve ; Briand, Olivier ; Bantubungi, Kadiombo ; Caron, Sandrine ; Bindels, Laure B. ; Delzenne, Nathalie M. ; Tailleux, Anne ; Staels, Bart ; Lestavel, Sophie
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-01, Vol.10 (1), p.174-174, Article 174
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ArticlesPeer ReviewedFull Text
Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle
Author / Creator:Wefers, Jakob ; van Moorsel, Dirk ; Hansen, Jan ; Connell, Niels J. ; Havekes, Bas ; Hoeks, Joris ; van Marken Lichtenbelt, Wouter D. ; Duez, Hélène ; Phielix, Esther ; Kalsbeek, Andries ; Boekschoten, Mark V. ; Hooiveld, Guido J. ; Hesselink, Matthijs K. C. ; Kersten, Sander ; Staels, Bart ; Scheer, Frank A. J. L. ; Schrauwen, Patrick
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.7789-7794
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ArticlesPeer ReviewedFull Text
Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model
Author / Creator:Bogie, Jeroen ; Hoeks, Cindy ; Schepers, Melissa ; Tiane, Assia ; Cuypers, Ann ; Leijten, Frank ; Chintapakorn, Yupyn ; Suttiyut, Thiti ; Pornpakakul, Surachai ; Struik, Dicky ; Kerksiek, Anja ; Liu, Hong-Bing ; Hellings, Niels ; Martinez-Martinez, Pilar ; Jonker, Johan W. ; Dewachter, Ilse ; Sijbrands, Eric ; Walter, Jochen ; Hendriks, Jerome ; Groen, Albert ; Staels, Bart ; Lütjohann, Dieter ; Vanmierlo, Tim ; Mulder, Monique
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-03, Vol.9 (1), p.4908, Article 4908
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ArticlesPeer ReviewedFull Text
Intestinal bile acid receptors are key regulators of glucose homeostasis
Author / Creator:Trabelsi, Mohamed-Sami ; Lestavel, Sophie ; Staels, Bart ; Collet, Xavier
Publisher:Cambridge, UK: Cambridge University Press
Journal title:Proceedings of the Nutrition Society, 2017-08, Vol.76 (3), p.192-202
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ArticlesPeer ReviewedFull Text
Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα
Author / Creator:Liang, Ning ; Damdimopoulos, Anastasius ; Goñi, Saioa ; Huang, Zhiqiang ; Vedin, Lise-Lotte ; Jakobsson, Tomas ; Giudici, Marco ; Ahmed, Osman ; Pedrelli, Matteo ; Barilla, Serena ; Alzaid, Fawaz ; Mendoza, Arturo ; Schröder, Tarja ; Kuiper, Raoul ; Parini, Paolo ; Hollenberg, Anthony ; Lefebvre, Philippe ; Francque, Sven ; Van Gaal, Luc ; Staels, Bart ; Venteclef, Nicolas ; Treuter, Eckardt ; Fan, Rongrong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-04, Vol.10 (1), p.1684-1684, Article 1684
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ArticlesPeer ReviewedFull Text
Therapeutic Roles of Peroxisome Proliferator–Activated Receptor Agonists
Author / Creator:STAELS, Bart ; FRUCHART, Jean-Charles
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2005-08, Vol.54 (8), p.2460-2470
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ArticlesPeer ReviewedFull Text
GIANT: galaxy-based tool for interactive analysis of transcriptomic data
Author / Creator:Vandel, Jimmy ; Gheeraert, Céline ; Staels, Bart ; Eeckhoute, Jérôme ; Lefebvre, Philippe ; Dubois-Chevalier, Julie
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-11, Vol.10 (1), p.19835-19835, Article 19835
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ArticlesPeer ReviewedFull Text
Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance
Author / Creator:Roumans, Kay H. M. ; Lindeboom, Lucas ; Veeraiah, Pandichelvam ; Remie, Carlijn M. E. ; Phielix, Esther ; Havekes, Bas ; Bruls, Yvonne M. H. ; Brouwers, Martijn C. G. J. ; Ståhlman, Marcus ; Alssema, Marjan ; Peters, Harry P. F. ; de Mutsert, Renée ; Staels, Bart ; Taskinen, Marja-Riitta ; Borén, Jan ; Schrauwen, Patrick ; Schrauwen-Hinderling, Vera B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-04, Vol.11 (1), p.1891-1891, Article 1891
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ArticlesPeer ReviewedFull Text
IFNγ-producing NK cells in adipose tissue are associated with hyperglycemia and insulin resistance in obese women
Author / Creator:Mogilenko, Denis A. ; Caiazzo, Robert ; L’homme, Laurent ; Pineau, Laurent ; Raverdy, Violeta ; Noulette, Jerome ; Derudas, Bruno ; Pattou, Francois ; Staels, Bart ; Dombrowicz, David
Publisher:London: Nature Publishing Group UK
Journal title:International Journal of Obesity, 2021-07, Vol.45 (7), p.1607-1617
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ArticlesPeer ReviewedFull Text
Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity
Author / Creator:PRAWITT, Janne ; ABDELKARIM, Mouaadh ; DORCHIES, Emilie ; DAOUDI, Mehdi ; LESTAVEL, Sophie ; GONZALEZ, Frank J ; ORESIC, Matej ; CARIOU, Bertrand ; KUIPERS, Folkert ; CARON, Sandrine ; STAELS, Bart ; STROEVE, Johanna H. M ; POPESCU, Iuliana ; DUEZ, Helene ; VELAGAPUDI, Vidya R ; DUMONT, Julie ; BOUCHAERT, Emmanuel ; VAN DIJK, Theo H ; LUCAS, Anthony
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2011-07, Vol.60 (7), p.1861-1871
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ArticlesPeer ReviewedFull Text
MuscleJ: a high-content analysis method to study skeletal muscle with a new Fiji tool
Author / Creator:Mayeuf-Louchart, Alicia ; Hardy, David ; Thorel, Quentin ; Roux, Pascal ; Gueniot, Lorna ; Briand, David ; Mazeraud, Aurélien ; Bouglé, Adrien ; Shorte, Spencer L ; Staels, Bart ; Chrétien, Fabrice ; Duez, Hélène ; Danckaert, Anne
Publisher:England: BioMed Central Ltd
Journal title:Skeletal muscle, 2018-08, Vol.8 (1), p.25-25, Article 25
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ArticlesPeer ReviewedFull Text
Adipose tissue macrophage infiltration and hepatocyte stress increase GDF-15 throughout development of obesity to MASH
Author / Creator:L’homme, Laurent ; Sermikli, Benan Pelin ; Haas, Joel T. ; Fleury, Sébastien ; Quemener, Sandrine ; Guinot, Valentine ; Barreby, Emelie ; Esser, Nathalie ; Caiazzo, Robert ; Verkindt, Hélène ; Legendre, Benjamin ; Raverdy, Violeta ; Cheval, Lydie ; Paquot, Nicolas ; Piette, Jacques ; Legrand-Poels, Sylvie ; Aouadi, Myriam ; Pattou, François ; Staels, Bart ; Dombrowicz, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-08, Vol.15 (1), p.7173-18, Article 7173
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Type 2 Diabetes; Type 2 diabetes: Understanding regulation of sugar levels for better treatment

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PPAR control of metabolism and cardiovascular functions

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Hepatic sexual dimorphism — implications for non-alcoholic fatty liver disease

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Cardiovascular Protection by Sodium Glucose Cotransporter 2 Inhibitors: Potential Mechanisms

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Distinct but complementary contributions of PPAR isotypes to energy homeostasis

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When the Clock stops ticking, metabolic syndrome explodes

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Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma

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Understanding lipid metabolism through hepatic steat-omics

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The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids

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Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

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Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model

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Intestinal bile acid receptors are key regulators of glucose homeostasis

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Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα

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Therapeutic Roles of Peroxisome Proliferator–Activated Receptor Agonists

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GIANT: galaxy-based tool for interactive analysis of transcriptomic data

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Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance

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IFNγ-producing NK cells in adipose tissue are associated with hyperglycemia and insulin resistance in obese women

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Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity

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MuscleJ: a high-content analysis method to study skeletal muscle with a new Fiji tool

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Adipose tissue macrophage infiltration and hepatocyte stress increase GDF-15 throughout development of obesity to MASH

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