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ArticlesPeer ReviewedFull Text
Emerging cell and cytokine targets in rheumatoid arthritis
Author / Creator:Burmester, Gerd R. ; Feist, Eugen ; Dörner, Thomas
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Rheumatology, 2014-02, Vol.10 (2), p.77-88
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ArticlesPeer ReviewedFull Text
1,25-Dihydroxyvitamin D Exerts Similar Immunosuppressive Effects as UVR but Is Dispensable for Local UVR-Induced Immunosuppression
Author / Creator:Schwarz, Agatha ; Navid, Fatemeh ; Sparwasser, Tim ; Clausen, Björn E. ; Schwarz, Thomas
Publisher:New York, NY: Elsevier Inc
Journal title:Journal of investigative dermatology, 2012-12, Vol.132 (12), p.2762-2769
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ArticlesPeer ReviewedFull Text
Separating graft-versus-leukemia from graft-versus-host disease in allogeneic hematopoietic stem cell transplantation
Author / Creator:Li, Jian-Ming ; Giver, Cynthia R ; Lu, Ying ; Hossain, Mohammad S ; Akhtari, Mojtaba ; Waller, Edmund K
Publisher:London: Future Medicine Ltd
Journal title:Immunotherapy, 2009-07, Vol.1 (4), p.599-621
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ArticlesFull Text
Application monitoring of the use of sorafenib in papillary renal cell carcinoma
Author / Creator:Schrader, A J ; Hegele, A ; Olbert, P ; Buer, J ; Jeron, A ; Hofmann, R
Publisher:Germany
Journal title:Urologe. Ausgabe A, 2007-09, Vol.46 (9), p.1291
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ArticlesPeer ReviewedFull Text
PD-1⁺ regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
Author / Creator:Kamada, Takahiro ; Togashi, Yosuke ; Tay, Christopher ; Ha, Danbee ; Sasaki, Akinori ; Nakamura, Yoshiaki ; Sato, Eiichi ; Fukuoka, Shota ; Tada, Yasuko ; Tanaka, Atsushi ; Morikawa, Hiromasa ; Kawazoe, Akihito ; Kinoshita, Takahiro ; Shitara, Kohei ; Sakaguchi, Shimon ; Nishikawa, Hiroyoshi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (20), p.9999-10008
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Regulatory T cells in cancer immunosuppression — implications for anticancer therapy
Author / Creator:Togashi, Yosuke ; Shitara, Kohei ; Nishikawa, Hiroyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2019-06, Vol.16 (6), p.356-371
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Regulatory T (Treg) cells in cancer: Can Treg cells be a new therapeutic target?
Author / Creator:Ohue, Yoshihiro ; Nishikawa, Hiroyoshi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2019-07, Vol.110 (7), p.2080-2089
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Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trial
Author / Creator:Rosenzwajg, Michelle ; Lorenzon, Roberta ; Cacoub, Patrice ; Pham, Hang Phuong ; Pitoiset, Fabien ; El Soufi, Karim ; RIbet, Claire ; Bernard, Claude ; Aractingi, Selim ; Banneville, Beatrice ; Beaugerie, Laurent ; Berenbaum, Francis ; Champey, Julien ; Chazouilleres, Olivier ; Corpechot, Christophe ; Fautrel, Bruno ; Mekinian, Arsène ; Regnier, Elodie ; Saadoun, David ; Salem, Joe-Elie ; Sellam, Jérémie ; Seksik, Philippe ; Daguenel-Nguyen, Anne ; Doppler, Valérie ; Mariau, Jéremie ; Vicaut, Eric ; Klatzmann, David
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2019-02, Vol.78 (2), p.209-217
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ArticlesPeer ReviewedFull Text
The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies
Author / Creator:Kumagai, Shogo ; Togashi, Yosuke ; Kamada, Takahiro ; Sugiyama, Eri ; Nishinakamura, Hitomi ; Takeuchi, Yoshiko ; Vitaly, Kochin ; Itahashi, Kota ; Maeda, Yuka ; Matsui, Shigeyuki ; Shibahara, Takuma ; Yamashita, Yasuho ; Irie, Takuma ; Tsuge, Ayaka ; Fukuoka, Shota ; Kawazoe, Akihito ; Udagawa, Hibiki ; Kirita, Keisuke ; Aokage, Keiju ; Ishii, Genichiro ; Kuwata, Takeshi ; Nakama, Kenta ; Kawazu, Masahito ; Ueno, Toshihide ; Yamazaki, Naoya ; Goto, Koichi ; Tsuboi, Masahiro ; Mano, Hiroyuki ; Doi, Toshihiko ; Shitara, Kohei ; Nishikawa, Hiroyoshi
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2020-11, Vol.21 (11), p.1346-1358
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ArticlesPeer ReviewedFull Text
Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy
Author / Creator:Yang, Riyao ; Sun, Linlin ; Li, Ching-Fei ; Wang, Yu-Han ; Yao, Jun ; Li, Hui ; Yan, Meisi ; Chang, Wei-Chao ; Hsu, Jung-Mao ; Cha, Jong-Ho ; Hsu, Jennifer L. ; Chou, Cheng-Wei ; Sun, Xian ; Deng, Yalan ; Chou, Chao-Kai ; Yu, Dihua ; Hung, Mien-Chie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.832-17, Article 832
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ArticlesPeer ReviewedFull Text
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
Author / Creator:Twyman-Saint Victor, Christina ; Rech, Andrew J. ; Maity, Amit ; Rengan, Ramesh ; Pauken, Kristen E. ; Stelekati, Erietta ; Benci, Joseph L. ; Xu, Bihui ; Dada, Hannah ; Odorizzi, Pamela M. ; Herati, Ramin S. ; Mansfield, Kathleen D. ; Patsch, Dana ; Amaravadi, Ravi K. ; Schuchter, Lynn M. ; Ishwaran, Hemant ; Mick, Rosemarie ; Pryma, Daniel A. ; Xu, Xiaowei ; Feldman, Michael D. ; Gangadhar, Tara C. ; Hahn, Stephen M. ; Wherry, E. John ; Vonderheide, Robert H. ; Minn, Andy J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-04, Vol.520 (7547), p.373-377
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ArticlesPeer ReviewedFull Text
CDK4/6 inhibition triggers anti-tumour immunity
Author / Creator:Goel, Shom ; DeCristo, Molly J. ; Watt, April C. ; BrinJones, Haley ; Sceneay, Jaclyn ; Li, Ben B. ; Khan, Naveed ; Ubellacker, Jessalyn M. ; Xie, Shaozhen ; Metzger-Filho, Otto ; Hoog, Jeremy ; Ellis, Matthew J. ; Ma, Cynthia X. ; Ramm, Susanne ; Krop, Ian E. ; Winer, Eric P. ; Roberts, Thomas M. ; Kim, Hye-Jung ; McAllister, Sandra S. ; Zhao, Jean J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-08, Vol.548 (7668), p.471-475
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ArticlesPeer ReviewedFull Text
Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis
Author / Creator:Wang, Yinghong ; Wiesnoski, Diana H. ; Helmink, Beth A. ; Gopalakrishnan, Vancheswaran ; Choi, Kati ; DuPont, Hebert L. ; Jiang, Zhi-Dong ; Abu-Sbeih, Hamzah ; Sanchez, Christopher A. ; Chang, Chia-Chi ; Parra, Edwin R. ; Francisco-Cruz, Alejandro ; Raju, Gottumukkala S. ; Stroehlein, John R. ; Campbell, Matthew T. ; Gao, Jianjun ; Subudhi, Sumit K. ; Maru, Dipen M. ; Blando, Jorge M. ; Lazar, Alexander J. ; Allison, James P. ; Sharma, Padmanee ; Tetzlaff, Michael T. ; Wargo, Jennifer A. ; Jenq, Robert R.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2018-12, Vol.24 (12), p.1804-1808
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ArticlesPeer ReviewedFull Text
Modulation of regulatory T cell function and stability by co-inhibitory receptors
Author / Creator:Lucca, Liliana E. ; Dominguez-Villar, Margarita
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2020-11, Vol.20 (11), p.680-693
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Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer
Author / Creator:Ali, Khaled ; Soond, Dalya R. ; Piñeiro, Roberto ; Hagemann, Thorsten ; Pearce, Wayne ; Lim, Ee Lyn ; Bouabe, Hicham ; Scudamore, Cheryl L. ; Hancox, Timothy ; Maecker, Heather ; Friedman, Lori ; Turner, Martin ; Okkenhaug, Klaus ; Vanhaesebroeck, Bart
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-06, Vol.510 (7505), p.407-411
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ArticlesPeer ReviewedFull Text
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
Author / Creator:Furusawa, Yukihiro ; Obata, Yuuki ; Fukuda, Shinji ; Endo, Takaho A. ; Nakato, Gaku ; Takahashi, Daisuke ; Nakanishi, Yumiko ; Uetake, Chikako ; Kato, Keiko ; Kato, Tamotsu ; Takahashi, Masumi ; Fukuda, Noriko N. ; Murakami, Shinnosuke ; Miyauchi, Eiji ; Hino, Shingo ; Atarashi, Koji ; Onawa, Satoshi ; Fujimura, Yumiko ; Lockett, Trevor ; Clarke, Julie M. ; Topping, David L. ; Tomita, Masaru ; Hori, Shohei ; Ohara, Osamu ; Morita, Tatsuya ; Koseki, Haruhiko ; Kikuchi, Jun ; Honda, Kenya ; Hase, Koji ; Ohno, Hiroshi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-12, Vol.504 (7480), p.446-450
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ArticlesPeer ReviewedFull Text
Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients
Author / Creator:Romano, Emanuela ; Kusio-Kobialka, Monika ; Foukas, Periklis G. ; Baumgaertner, Petra ; Meyer, Christiane ; Ballabeni, Pierluigi ; Michielin, Olivier ; Weide, Benjamin ; Romero, Pedro ; Speiser, Daniel E.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-05, Vol.112 (19), p.6140-6145
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ArticlesPeer ReviewedFull Text
Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites
Author / Creator:Thorburn, Alison N. ; McKenzie, Craig I. ; Shen, Sj ; Stanley, Dragana ; Macia, Laurence ; Mason, Linda J. ; Roberts, Laura K. ; Wong, Connie H. Y. ; Shim, Raymond ; Robert, Remy ; Chevalier, Nina ; Tan, Jian K. ; Mariño, Eliana ; Moore, Rob J. ; Wong, Lee ; McConville, Malcolm J. ; Tull, Dedreia L. ; Wood, Lisa G. ; Murphy, Vanessa E. ; Mattes, Joerg ; Gibson, Peter G. ; Mackay, Charles R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-06, Vol.6 (1), p.7320-7320, Article 7320
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ArticlesPeer ReviewedFull Text
The role of vitamin D in increasing circulating T regulatory cell numbers and modulating T regulatory cell phenotypes in patients with inflammatory disease or in healthy volunteers: A systematic revie...
Author / Creator:Fisher, Sheila A ; Rahimzadeh, Mana ; Brierley, Charlotte ; Gration, Betty ; Doree, Carolyn ; Kimber, Catherine E ; Plaza Cajide, Alicia ; Lamikanra, Abigail A ; Roberts, David J
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-09, Vol.14 (9), p.e0222313-e0222313
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ArticlesPeer ReviewedFull Text
De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
Author / Creator:Berod, Luciana ; Friedrich, Christin ; Nandan, Amrita ; Freitag, Jenny ; Hagemann, Stefanie ; Harmrolfs, Kirsten ; Sandouk, Aline ; Hesse, Christina ; Castro, Carla N ; Bähre, Heike ; Tschirner, Sarah K ; Gorinski, Nataliya ; Gohmert, Melanie ; Mayer, Christian T ; Huehn, Jochen ; Ponimaskin, Evgeni ; Abraham, Wolf-Rainer ; Müller, Rolf ; Lochner, Matthias ; Sparwasser, Tim
Publisher:London: Nature Publishing Group UK
Journal title:Nature medicine, 2014-11, Vol.20 (11), p.1327-1333
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Emerging cell and cytokine targets in rheumatoid arthritis

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1,25-Dihydroxyvitamin D Exerts Similar Immunosuppressive Effects as UVR but Is Dispensable for Local UVR-Induced Immunosuppression

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Separating graft-versus-leukemia from graft-versus-host disease in allogeneic hematopoietic stem cell transplantation

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Application monitoring of the use of sorafenib in papillary renal cell carcinoma

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PD-1⁺ regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer

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Regulatory T cells in cancer immunosuppression — implications for anticancer therapy

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Regulatory T (Treg) cells in cancer: Can Treg cells be a new therapeutic target?

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Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trial

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The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

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Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy

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Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

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CDK4/6 inhibition triggers anti-tumour immunity

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Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

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Modulation of regulatory T cell function and stability by co-inhibitory receptors

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Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

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Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

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Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

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Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites

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The role of vitamin D in increasing circulating T regulatory cell numbers and modulating T regulatory cell phenotypes in patients with inflammatory disease or in healthy volunteers: A systematic revie...

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De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

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