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ArticlesPeer ReviewedFull Text
Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis
Author / Creator:Nakazawa, Seshiru ; Oikawa, Daisuke ; Ishii, Ryohei ; Ayaki, Takashi ; Takahashi, Hirotaka ; Takeda, Hiroyuki ; Ishitani, Ryuichiro ; Kamei, Kiyoko ; Takeyoshi, Izumi ; Kawakami, Hideshi ; Iwai, Kazuhiro ; Hatada, Izuho ; Sawasaki, Tatsuya ; Ito, Hidefumi ; Nureki, Osamu ; Tokunaga, Fuminori
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-08, Vol.7 (1), p.12547-12547, Article 12547
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ArticlesPeer ReviewedFull Text
Analysis of Sparse Trajectory Features Based on Mobile Device Location for User Group Classification Using Gaussian Mixture Model
Author / Creator:Kakimoto, Yohei ; Omae, Yuto ; Takahashi, Hirotaka
Publisher:Basel: MDPI AG
Journal title:Applied sciences, 2025-01, Vol.15 (2), p.982
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ArticlesPeer ReviewedFull Text
Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro
Author / Creator:Nomura, Shunsuke ; Takahashi, Hirotaka ; Suzuki, Junpei ; Kuwahara, Makoto ; Yamashita, Masakatsu ; Sawasaki, Tatsuya
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-11, Vol.9 (1), p.17335-12, Article 17335
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ArticlesPeer ReviewedFull Text
OTUD1 deubiquitinase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways
Author / Creator:Oikawa, Daisuke ; Gi, Min ; Kosako, Hidetaka ; Shimizu, Kouhei ; Takahashi, Hirotaka ; Shiota, Masayuki ; Hosomi, Shuhei ; Komakura, Keidai ; Wanibuchi, Hideki ; Tsuruta, Daisuke ; Sawasaki, Tatsuya ; Tokunaga, Fuminori
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2022-08, Vol.13 (8), p.694-694, Article 694
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ArticlesPeer ReviewedFull Text
Inattentive Driving Detection Using Body-Worn Sensors: Feasibility Study
Author / Creator:Akiduki, Takuma ; Nagasawa, Jun ; Zhang, Zhong ; Omae, Yuto ; Arakawa, Toshiya ; Takahashi, Hirotaka
Publisher:Switzerland: MDPI AG
Journal title:Sensors (Basel, Switzerland), 2022-01, Vol.22 (1), p.352
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ArticlesPeer ReviewedFull Text
AGIA Tag System Based on a High Affinity Rabbit Monoclonal Antibody against Human Dopamine Receptor D1 for Protein Analysis
Author / Creator:Yano, Tomoya ; Takeda, Hiroyuki ; Uematsu, Atsushi ; Yamanaka, Satoshi ; Nomura, Shunsuke ; Nemoto, Keiichirou ; Iwasaki, Takahiro ; Takahashi, Hirotaka ; Sawasaki, Tatsuya
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-06, Vol.11 (6), p.e0156716-e0156716
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ArticlesPeer ReviewedFull Text
Automated design of digital filters using convolutional neural networks for extracting ringdown gravitational waves
Author / Creator:Sakai, Kazuki ; Odonchimed, Sodtavilan ; Takano, Mitsuki ; Takahashi, Hirotaka
Publisher:Bristol: IOP Publishing
Journal title:Machine learning: science and technology, 2024-12, Vol.5 (4), p.45043
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ArticlesPeer ReviewedFull Text
Unsupervised learning architecture for classifying the transient noise of interferometric gravitational-wave detectors
Author / Creator:Sakai, Yusuke ; Itoh, Yousuke ; Jung, Piljong ; Kokeyama, Keiko ; Kozakai, Chihiro ; Nakahira, Katsuko T. ; Oshino, Shoichi ; Shikano, Yutaka ; Takahashi, Hirotaka ; Uchiyama, Takashi ; Ueshima, Gen ; Washimi, Tatsuki ; Yamamoto, Takahiro ; Yokozawa, Takaaki
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-06, Vol.12 (1), p.9935-9935, Article 9935
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Features gradient-based signals selection algorithm of linear complexity for convolutional neural networks
Author / Creator:Omae, Yuto ; Sakai, Yusuke ; Takahashi, Hirotaka
Publisher:AIMS Press
Journal title:AIMS mathematics, 2024, Vol.9 (1), p.792-817
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Fast screening framework for infection control scenario identification
Author / Creator:Kakimoto, Yohei ; Omae, Yuto ; Toyotani, Jun ; Takahashi, Hirotaka
Publisher:United States: AIMS Press
Journal title:Mathematical biosciences and engineering : MBE, 2022-01, Vol.19 (12), p.12316-12333
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ArticlesPeer ReviewedFull Text
Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction between E3 Ligases and Substrate Proteins
Author / Creator:Takahashi, Hirotaka ; Uematsu, Atsushi ; Yamanaka, Satoshi ; Imamura, Mei ; Nakajima, Tatsuro ; Doi, Kousuke ; Yasuoka, Saki ; Takahashi, Chikako ; Takeda, Hiroyuki ; Sawasaki, Tatsuya
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-06, Vol.11 (6), p.e0156718-e0156718
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ArticlesPeer ReviewedFull Text
Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation
Author / Creator:Ohta, Kazuyoshi ; Ito, Masahiko ; Chida, Takeshi ; Nakashima, Kenji ; Sakai, Satoshi ; Kanegae, Yumi ; Kawasaki, Hideya ; Aoshima, Takuya ; Takabayashi, Shuji ; Takahashi, Hirotaka ; Kawata, Kazuhito ; Shoji, Ikuo ; Sawasaki, Tatsuya ; Suda, Takafumi ; Suzuki, Tetsuro
Publisher:San Francisco: Public Library of Science
Journal title:PLoS pathogens, 2023-08, Vol.19 (8), p.e1011591-e1011591
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ArticlesPeer ReviewedFull Text
Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication
Author / Creator:Suzuki, Youichi ; Chin, Wei-Xin ; Han, Qi'En ; Ichiyama, Koji ; Lee, Ching Hua ; Eyo, Zhi Wen ; Ebina, Hirotaka ; Takahashi, Hirotaka ; Takahashi, Chikako ; Tan, Beng Hui ; Hishiki, Takayuki ; Ohba, Kenji ; Matsuyama, Toshifumi ; Koyanagi, Yoshio ; Tan, Yee-Joo ; Sawasaki, Tatsuya ; Chu, Justin Jang Hann ; Vasudevan, Subhash G ; Sano, Kouichi ; Yamamoto, Naoki
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2016-01, Vol.12 (1), p.e1005357-e1005357
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ArticlesPeer ReviewedFull Text
Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway
Author / Creator:Nakai, Kazuki ; Lin, Hancheng ; Yamano, Shotaro ; Tanaka, Shinya ; Kitamoto, Sho ; Saitoh, Hitoshi ; Sakuma, Kenta ; Kurauchi, Junpei ; Akter, Eilma ; Konno, Masamitsu ; Ishibashi, Kojiro ; Kamata, Ryo ; Ohashi, Akihiro ; Koseki, Jun ; Takahashi, Hirotaka ; Yokoyama, Hideshi ; Shiraki, Yukihiro ; Enomoto, Atsushi ; Abe, Sohei ; Hayakawa, Yoku ; Ushiku, Tetsuo ; Mutoh, Michihiro ; Fujita, Yasuyuki ; Kon, Shunsuke
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-11, Vol.14 (1), p.7048-7048, Article 7048
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ArticlesPeer ReviewedFull Text
SIRVVD model-based verification of the effect of first and second doses of COVID-19/SARS-CoV-2 vaccination in Japan
Author / Creator:Omae, Yuto ; Kakimoto, Yohei ; Sasaki, Makoto ; Toyotani, Jun ; Hara, Kazuyuki ; Gon, Yasuhiro ; Takahashi, Hirotaka
Publisher:United States: AIMS Press
Journal title:Mathematical biosciences and engineering : MBE, 2022-01, Vol.19 (1), p.1026-1040
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Newsletter articlesFull Text
WIPO PUBLISHES PATENT OF HITACHI, TAKAHASHI HIROTAKA, TOMITA YASUSHI, KAWAMURA HIDEYUKI, OGAWA JUNPEI FOR "SYSTEM, METHOD AND COMPUTER PROGRAM FOR ENERGY CONSUMPTION MANAGEMENT" (JAPANESE INVENTORS)
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2012
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Effectiveness of the COVID-19 Contact-Confirming Application (COCOA) Based on Multi-Agent Simulation
Author / Creator:Omae, Yuto ; Toyotani, Jun ; Hara, Kazuyuki ; Gon, Yasuhiro ; Takahashi, Hirotaka
Publisher:Tokyo: Fuji Technology Press Co. Ltd
Journal title:Journal of advanced computational intelligence and intelligent informatics, 2021-11, Vol.25 (6), p.931-943
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SIR model-based verification of effect of COVID-19 Contact-Confirming Application (COCOA) on reducing infectors in Japan
Author / Creator:Omae, Yuto ; Kakimoto, Yohei ; Toyotani, Jun ; Hara, Kazuyuki ; Gon, Yasuhiro ; Takahashi, Hirotaka
Publisher:AIMS Press
Journal title:Mathematical biosciences and engineering : MBE, 2021-09, Vol.18 (5), p.6506-6526
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Suppression of DS1 phosphatidic acid phosphatase confirms resistance to Ralstonia solanacearum in Nicotiana benthamiana
Author / Creator:Nakano, Masahito ; Nishihara, Masahiro ; Yoshioka, Hirofumi ; Takahashi, Hirotaka ; Sawasaki, Tatsuya ; Ohnishi, Kouhei ; Hikichi, Yasufumi ; Kiba, Akinori
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-09, Vol.8 (9), p.e75124-e75124
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HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains
Author / Creator:Shibata, Yuri ; Tokunaga, Fuminori ; Goto, Eiji ; Komatsu, Ginga ; Gohda, Jin ; Saeki, Yasushi ; Tanaka, Keiji ; Takahashi, Hirotaka ; Sawasaki, Tatsuya ; Inoue, Satoshi ; Oshiumi, Hiroyuki ; Seya, Tsukasa ; Nakano, Hiroyasu ; Tanaka, Yuetsu ; Iwai, Kazuhiro ; Inoue, Jun-Ichiro
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2017-01, Vol.13 (1), p.e1006162-e1006162
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Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis

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Analysis of Sparse Trajectory Features Based on Mobile Device Location for User Group Classification Using Gaussian Mixture Model

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Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro

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OTUD1 deubiquitinase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways

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Inattentive Driving Detection Using Body-Worn Sensors: Feasibility Study

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AGIA Tag System Based on a High Affinity Rabbit Monoclonal Antibody against Human Dopamine Receptor D1 for Protein Analysis

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Automated design of digital filters using convolutional neural networks for extracting ringdown gravitational waves

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Unsupervised learning architecture for classifying the transient noise of interferometric gravitational-wave detectors

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Features gradient-based signals selection algorithm of linear complexity for convolutional neural networks

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Fast screening framework for infection control scenario identification

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Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction between E3 Ligases and Substrate Proteins

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Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation

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Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication

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Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway

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SIRVVD model-based verification of the effect of first and second doses of COVID-19/SARS-CoV-2 vaccination in Japan

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WIPO PUBLISHES PATENT OF HITACHI, TAKAHASHI HIROTAKA, TOMITA YASUSHI, KAWAMURA HIDEYUKI, OGAWA JUNPEI FOR "SYSTEM, METHOD AND COMPUTER PROGRAM FOR ENERGY CONSUMPTION MANAGEMENT" (JAPANESE INVENTORS)

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Effectiveness of the COVID-19 Contact-Confirming Application (COCOA) Based on Multi-Agent Simulation

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SIR model-based verification of effect of COVID-19 Contact-Confirming Application (COCOA) on reducing infectors in Japan

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Suppression of DS1 phosphatidic acid phosphatase confirms resistance to Ralstonia solanacearum in Nicotiana benthamiana

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HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains

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