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ArticlesPeer ReviewedFull Text
Relationship between neutropenia caused by nanoliposomal irinotecan/fluorouracil/leucovorin and treatment outcomes in the NAPOLEON-2 study (NN-2301)
Author / Creator:Araki, Tomonori ; Sonoda, Yuki ; Shimokawa, Mototsugu ; Otsuka, Taiga ; Hayashi, Kohei ; Honda, Takuya ; Nakao, Kazuhiko ; Shibuki, Taro ; Nakazawa, Junichi ; Arima, Shiho ; Miwa, Keisuke ; Okabe, Yoshinobu ; Koga, Futa ; Ueda, Yujiro ; Kubotsu, Yoshihito ; Shimokawa, Hozumi ; Takeshita, Shigeyuki ; Komori, Azusa ; Nishikawa, Kazuo ; Otsu, Satoshi ; Hosokawa, Ayumu ; Oda, Hisanobu ; Sakai, Tatsunori ; Arita, Shuji ; Kawahira, Machiko ; Taguchi, Hiroki ; Tsuneyoshi, Kengo ; Kawaguchi, Yasunori ; Fujita, Toshihiro ; Sakae, Takahiro ; Shirakawa, Tsuyoshi ; Mizuta, Toshihiko ; Mitsugi, Kenji
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-01, Vol.15 (1), p.3427-12, Article 3427
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ArticlesPeer ReviewedFull Text
A multicenter retrospective observational NAPOLEON2 study of nanoliposomal irinotecan with fluorouracil and folinic acid in patients with unresectable pancreatic cancer
Author / Creator:Kodama, Tomoko ; Imajima, Takashi ; Shimokawa, Mototsugu ; Otsuka, Taiga ; Kawahira, Masahiro ; Nakazawa, Junichi ; Hori, Takeshi ; Shibuki, Taro ; Arima, Shiho ; Ido, Akio ; Miwa, Keisuke ; Okabe, Yoshinobu ; Koga, Futa ; Ueda, Yujiro ; Kubotsu, Yoshihito ; Shimokawa, Hozumi ; Takeshita, Shigeyuki ; Nishikawa, Kazuo ; Komori, Azusa ; Otsu, Satoshi ; Hosokawa, Ayumu ; Sakai, Tatsunori ; Sakai, Kenji ; Oda, Hisanobu ; Kawahira, Machiko ; Arita, Shuji ; Honda, Takuya ; Taguchi, Hiroki ; Tsuneyoshi, Kengo ; Kawaguchi, Yasunori ; Fujita, Toshihiro ; Sakae, Takahiro ; Shirakawa, Tsuyoshi ; Mizuta, Toshihiko ; Mitsugi, Kenji
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-05, Vol.14 (1), p.12422-10, Article 12422
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ArticlesPeer ReviewedFull Text
Nanoliposomal irinotecan with fluorouracil and folinic acid, FOLFIRINOX, and S-1 as second-line treatment for unresectable pancreatic cancer after gemcitabine/nab-paclitaxel
Author / Creator:Shibuki, Taro ; Otsuka, Taiga ; Shimokawa, Mototsugu ; Nakazawa, Junichi ; Arima, Shiho ; Fukahori, Masaru ; Miwa, Keisuke ; Okabe, Yoshinobu ; Koga, Futa ; Ueda, Yujiro ; Kubotsu, Yoshihito ; Makiyama, Akitaka ; Shimokawa, Hozumi ; Takeshita, Shigeyuki ; Nishikawa, Kazuo ; Komori, Azusa ; Otsu, Satoshi ; Hosokawa, Ayumu ; Sakai, Tatsunori ; Oda, Hisanobu ; Kawahira, Machiko ; Arita, Shuji ; Honda, Takuya ; Taguchi, Hiroki ; Tsuneyoshi, Kengo ; Kawaguchi, Yasunori ; Fujita, Toshihiro ; Sakae, Takahiro ; Nio, Kenta ; Ide, Yasushi ; Ureshino, Norio ; Shirakawa, Tsuyoshi ; Mizuta, Toshihiko ; Mitsugi, Kenji
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-07, Vol.14 (1), p.16906-10, Article 16906
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ArticlesPeer ReviewedFull Text
Comparison of inflammatory markers before and after nanoliposomal irinotecan and fluorouracil with folic acid in patients with pancreatic cancer: results from the NAPOLEON-2 study (NN-2302)
Author / Creator:Araki, Tomonori ; Hayashi, Kohei ; Shimokawa, Mototsugu ; Otsuka, Taiga ; Sonoda, Yuki ; Honda, Takuya ; Shibuki, Taro ; Nakazawa, Junichi ; Arima, Shiho ; Miwa, Keisuke ; Koga, Futa ; Ueda, Yujiro ; Kubotsu, Yoshihito ; Shimokawa, Hozumi ; Takeshita, Shigeyuki ; Nishikawa, Kazuo ; Komori, Azusa ; Otsu, Satoshi ; Hosokawa, Ayumu ; Sakai, Tatsunori ; Oda, Hisanobu ; Kawahira, Machiko ; Arita, Shuji ; Taguchi, Hiroki ; Tsuneyoshi, Kengo ; Fujita, Toshihiro ; Sakae, Takahiro ; Kawaguchi, Yasunori ; Shirakawa, Tsuyoshi ; Mizuta, Toshihiko ; Mitsugi, Kenji
Publisher:England: SAGE Publishing
Journal title:Therapeutic advances in medical oncology, 2025-01, Vol.17, p.17588359251320768
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ArticlesPeer ReviewedFull Text
Interferon-α-induced mTOR activation is an anti-hepatitis C virus signal via the phosphatidylinositol 3-kinase-Akt-independent pathway
Author / Creator:Matsumoto, Azusa ; Ichikawa, Tatsuki ; Nakao, Kazuhiko ; Miyaaki, Hisamitsu ; Hirano, Kumi ; Fujimito, Masumi ; Akiyama, Motohisa ; Miuma, Satoshi ; Ozawa, Eisuke ; Shibata, Hidetaka ; Takeshita, Shigeyuki ; Yamasaki, Hironori ; Ikeda, Masanori ; Kato, Nobuyuki ; Eguchi, Katsumi
Publisher:Japan: Japan : Springer Japan
Journal title:Journal of gastroenterology, 2009-08, Vol.44 (8), p.856-863
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ArticlesPeer ReviewedFull Text
Geranylgeranylacetone has anti-hepatitis C virus activity via activation of mTOR in human hepatoma cells
Author / Creator:Takeshita, Shigeyuki ; Ichikawa, Tatsuki ; Taura, Naota ; Miyaaki, Hisamitsu ; Matsuzaki, Toshihisa ; Otani, Masashi ; Muraoka, Toru ; Akiyama, Motohisa ; Miuma, Satoshi ; Ozawa, Eisuke ; Ikeda, Masanori ; Kato, Nobuyuki ; Isomoto, Hajime ; Takeshima, Fuminao ; Nakao, Kazuhiko
Publisher:Japan: Springer Japan
Journal title:Journal of gastroenterology, 2012-02, Vol.47 (2), p.195-202
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ArticlesPeer ReviewedFull Text
Second-line chemotherapy with irinotecan plus cisplatin after the failure of S-1 monotherapy for advanced gastric cancer
Author / Creator:Takahari, Daisuke ; Shimada, Yasuhiro ; Takeshita, Shigeyuki ; Nishitani, Hitoshi ; Takashima, Atsuo ; Okita, Natsuko ; Hirashima, Yoshinori ; Kato, Ken ; Hamaguchi, Tetsuya ; Yamada, Yasuhide ; Shirao, Kuniaki
Publisher:Japan: Japan : Springer Japan
Journal title:Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2010-08, Vol.13 (3), p.186-190
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ArticlesFull Text
Insulin-induced mTOR activity exhibits anti-hepatitis C virus activity
Author / Creator:Muraoka, Toru
Publisher:Greece: Spandidos Publications UK Ltd
Journal title:Molecular medicine reports, 2012-02, Vol.5 (2), p.331-335
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ArticlesPeer ReviewedFull Text
Predictive Value of the Phosphorylation of Signal Transducers and Activators of Transcription in the Outcome of Interferon Therapy for Chronic Hepatitis C
Author / Creator:Miyaaki, Hisamitsu ; Ichikawa, Tatsuki ; Nakao, Kazuhiko ; Takeshita, Shigeyuki ; Shibata, Hidetaka ; Ozawa, Eisuke ; Akiyama, Motohisa ; Miuma, Satoshi ; Eguchi, Katsumi
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Intervirology, 2008-01, Vol.51 (6), p.394-399
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ArticlesPeer ReviewedFull Text
Relationship between Regulatory T Cells and the Combination of Pegylated Interferon and Ribavirin for the Treatment of Chronic Hepatitis Type C
Author / Creator:Akiyama, Motohisa ; Ichikawa, Tatuki ; Miyaaki, Hisamitsu ; Motoyoshi, Yasuhide ; Takeshita, Shigeyuki ; Ozawa, Eisuke ; Miuma, Satoshi ; Shibata, Hidetaka ; Taura, Naota ; Nakao, Kazuhiko
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Intervirology, 2010-01, Vol.53 (3), p.154-160
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ArticlesPeer ReviewedFull Text
Interferon-[alpha]-induced mTOR activation is an anti-hepatitis C virus signal via the phosphatidylinositol 3-kinase-Akt-independent pathway
Author / Creator:Matsumoto, Azusa ; Ichikawa, Tatsuki ; Nakao, Kazuhiko ; Miyaaki, Hisamitsu ; Hirano, Kumi ; Fujimito, Masumi ; Akiyama, Motohisa ; Miuma, Satoshi ; Ozawa, Eisuke ; Shibata, Hidetaka ; Takeshita, Shigeyuki ; Yamasaki, Hironori ; Ikeda, Masanori ; Kato, Nobuyuki ; Eguchi, Katsumi
Publisher:Tokyo: Springer Nature B.V
Journal title:Journal of gastroenterology, 2009-08, Vol.44 (8), p.856
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Relationship between neutropenia caused by nanoliposomal irinotecan/fluorouracil/leucovorin and treatment outcomes in the NAPOLEON-2 study (NN-2301)

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A multicenter retrospective observational NAPOLEON2 study of nanoliposomal irinotecan with fluorouracil and folinic acid in patients with unresectable pancreatic cancer

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Nanoliposomal irinotecan with fluorouracil and folinic acid, FOLFIRINOX, and S-1 as second-line treatment for unresectable pancreatic cancer after gemcitabine/nab-paclitaxel

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Comparison of inflammatory markers before and after nanoliposomal irinotecan and fluorouracil with folic acid in patients with pancreatic cancer: results from the NAPOLEON-2 study (NN-2302)

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Interferon-α-induced mTOR activation is an anti-hepatitis C virus signal via the phosphatidylinositol 3-kinase-Akt-independent pathway

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Geranylgeranylacetone has anti-hepatitis C virus activity via activation of mTOR in human hepatoma cells

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Second-line chemotherapy with irinotecan plus cisplatin after the failure of S-1 monotherapy for advanced gastric cancer

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Insulin-induced mTOR activity exhibits anti-hepatitis C virus activity

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Predictive Value of the Phosphorylation of Signal Transducers and Activators of Transcription in the Outcome of Interferon Therapy for Chronic Hepatitis C

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Relationship between Regulatory T Cells and the Combination of Pegylated Interferon and Ribavirin for the Treatment of Chronic Hepatitis Type C

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Interferon-[alpha]-induced mTOR activation is an anti-hepatitis C virus signal via the phosphatidylinositol 3-kinase-Akt-independent pathway

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