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Newsletter articlesFull Text
INTERNATIONAL PATENT: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CHILDREN'S HOSPITAL RESEARCH CENTER AT OAKLAND, MARTIN, DAVID I.K., DEWITT, MARK, WALTERS, MARK C., MAGIS, WENDY J., THANGAVEL, SARAV...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2023
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ArticlesPeer ReviewedFull Text
Advancing Precision Medicine: Recent Innovations in Gene Editing Technologies
Author / Creator:Koodamvetty, Abhijith ; Thangavel, Saravanabhavan
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Advanced science, 2025-04, Vol.12 (14), p.e2410237-n/a
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ArticlesPeer ReviewedFull Text
Endocytosis as a critical regulator of hematopoietic stem cell fate —implications for hematopoietic stem cell and gene therapy
Author / Creator:Babu Chandraprabha, Prathibha ; Thangavel, Saravanabhavan
Publisher:England: BioMed Central Ltd
Journal title:Stem cell research & therapy, 2024-09, Vol.15 (1), p.319-4, Article 319
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ArticlesPeer ReviewedFull Text
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition
Author / Creator:Berti, Matteo ; Ray Chaudhuri, Arnab ; Thangavel, Saravanabhavan ; Gomathinayagam, Shivasankari ; Kenig, Sasa ; Vujanovic, Marko ; Odreman, Federico ; Glatter, Timo ; Graziano, Simona ; Mendoza-Maldonado, Ramiro ; Marino, Francesca ; Lucic, Bojana ; Biasin, Valentina ; Gstaiger, Matthias ; Aebersold, Ruedi ; Sidorova, Julia M ; Monnat, Raymond J ; Lopes, Massimo ; Vindigni, Alessandro
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2013-03, Vol.20 (3), p.347-354
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ArticlesPeer ReviewedFull Text
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
Author / Creator:Ravi, Nithin Sam ; Wienert, Beeke ; Wyman, Stacia K ; Bell, Henry William ; George, Anila ; Mahalingam, Gokulnath ; Vu, Jonathan T ; Prasad, Kirti ; Bandlamudi, Bhanu Prasad ; Devaraju, Nivedhitha ; Rajendiran, Vignesh ; Syedbasha, Nazar ; Pai, Aswin Anand ; Nakamura, Yukio ; Kurita, Ryo ; Narayanasamy, Muthuraman ; Balasubramanian, Poonkuzhali ; Thangavel, Saravanabhavan ; Marepally, Srujan ; Velayudhan, Shaji R ; Srivastava, Alok ; DeWitt, Mark A ; Crossley, Merlin ; Corn, Jacob E ; Mohankumar, Kumarasamypet M
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2022-02, Vol.11
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ArticlesPeer ReviewedFull Text
Homology-directed gene-editing approaches for hematopoietic stem and progenitor cell gene therapy
Author / Creator:Azhagiri, Manoj Kumar K. ; Babu, Prathibha ; Venkatesan, Vigneshwaran ; Thangavel, Saravanabhavan
Publisher:London: BioMed Central Ltd
Journal title:Stem cell research & therapy, 2021-09, Vol.12 (1), p.1-500, Article 500
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ArticlesPeer ReviewedFull Text
Correlating the differences in the receptor binding domain of SARS-CoV-2 spike variants on their interactions with human ACE2 receptor
Author / Creator:Mahalingam, Gokulnath ; Arjunan, Porkizhi ; Periyasami, Yogapriya ; Dhyani, Ajay Kumar ; Devaraju, Nivedita ; Rajendiran, Vignesh ; Christopher, Abisha Crystal ; KT, Ramya Devi ; Dhanasingh, Immanuel ; Thangavel, Saravanabhavan ; Murugesan, Mohankumar ; Moorthy, Mahesh ; Srivastava, Alok ; Marepally, Srujan
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-05, Vol.13 (1), p.8743-8743, Article 8743
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ArticlesPeer ReviewedFull Text
The Strategies and Challenges of CCR5 Gene Editing in Hematopoietic Stem and Progenitor Cells for the Treatment of HIV
Author / Creator:Karuppusamy, Karthik V ; Babu Prathibha ; Thangavel Saravanabhavan
Publisher:New York: Springer Nature B.V
Journal title:Stem cell reviews and reports, 2021-10, Vol.17 (5), p.1607-1618
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ArticlesPeer ReviewedFull Text
Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications
Author / Creator:Bagchi, Abhirup ; Devaraju, Nivedhitha ; Chambayil, Karthik ; Rajendiran, Vignesh ; Venkatesan, Vigneshwaran ; Sayed, Nilofer ; Pai, Aswin Anand ; Nath, Aneesha ; David, Ernest ; Nakamura, Yukio ; Balasubramanian, Poonkuzhali ; Srivastava, Alok ; Thangavel, Saravanabhavan ; Mohankumar, Kumarasamypet M. ; Velayudhan, Shaji R.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-08, Vol.12 (1), p.14033-13, Article 14033
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ArticlesPeer ReviewedFull Text
Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies
Author / Creator:Chandraprabha, Prathibha Babu ; Azhagiri, Manoj Kumar K. ; Venkatesan, Vigneshwaran ; Magis, Wendy ; Prasad, Kirti ; Suresh, Sevanthy ; Pai, Aswin Anand ; Marepally, Srujan ; Srivastava, Alok ; Mohankumar, Kumarasamypet Murugesan ; Martin, David I. K. ; Thangavel, Saravanabhavan
Publisher:England: BioMed Central
Journal title:Stem cell research & therapy, 2024-12, Vol.15 (1), p.504-19, Article 504
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ArticlesPeer ReviewedFull Text
Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication
Author / Creator:Xu, Dongyi ; Muniandy, Parameswary ; Leo, Elisabetta ; Yin, Jinhu ; Thangavel, Saravanabhavan ; Shen, Xi ; Ii, Miki ; Agama, Keli ; Guo, Rong ; Fox III, David ; Meetei, Amom Ruhikanta ; Wilson, Lauren ; Nguyen, Huy ; Weng, Nan-ping ; Brill, Steven J ; Li, Lei ; Vindigni, Alessandro ; Pommier, Yves ; Seidman, Michael ; Wang, Weidong
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2010-09, Vol.29 (18), p.3140-3155
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ArticlesPeer ReviewedFull Text
Direct Generation of Immortalized Erythroid Progenitor Cell Lines from Peripheral Blood Mononuclear Cells
Author / Creator:Bagchi, Abhirup ; Nath, Aneesha ; Thamodaran, Vasanth ; Ijee, Smitha ; Palani, Dhavapriya ; Rajendiran, Vignesh ; Venkatesan, Vigneshwaran ; Datari, Phaneendra ; Pai, Aswin Anand ; Janet, Nancy Beryl ; Balasubramanian, Poonkuzhali ; Nakamura, Yukio ; Srivastava, Alok ; Mohankumar, Kumarasamypet Murugesan ; Thangavel, Saravanabhavan ; Velayudhan, Shaji R.
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2021-03, Vol.10 (3), p.523
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ArticlesPeer ReviewedFull Text
Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for [beta]-hemoglobinopathies
Author / Creator:Chandraprabha, Prathibha Babu ; Azhagiri, Manoj Kumar K ; Venkatesan, Vigneshwaran ; Magis, Wendy ; Prasad, Kirti ; Suresh, Sevanthy ; Pai, Aswin Anand ; Marepally, Srujan ; Srivastava, Alok ; Mohankumar, Kumarasamypet Murugesan ; Martin, David I. K ; Thangavel, Saravanabhavan
Publisher:BioMed Central Ltd
Journal title:Stem cell research & therapy, 2024-12, Vol.15 (1)
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ArticlesFull Text
Correlating the differences in the receptor binding domain of SARS-CoV-2 spike variants on their interactions with human ACE2 receptor
Author / Creator:Mahalingam, Gokulnath ; Arjunan, Porkizhi ; Periasami, Yogapriya ; Dhyani, Ajay Kumar ; Devaraju, Nivedhitha ; Vignesh Rajendiran ; Abhisha, Crystal Christopher ; Ramya Devi Kt ; Darasingh, Immanuel ; Thangavel, Saravanabhavan ; Murugesan, Mohankumar ; Moorthy, Mahesh ; Srivastava, Alok ; Marepally, Srujan
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-09
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ArticlesFull Text
Identification of novel HPFH-like mutations by CRISPR base editing that elevates the expression of fetal hemoglobin
Author / Creator:Nithin Sam Ravi ; Beeke Wienert ; Wyman, Stacia K ; Vu, Jonathan ; Aswin Anand Pai ; Balasubramanian, Poonkuzhali ; Nakamura, Yukio ; Kurita, Ryo ; Marepally, Srujan ; Thangavel, Saravanabhavan ; Velayudhan, Shaji R ; Srivastava, Alok ; Dewitt, Mark A ; Corn, Jacob E ; Kumarasamypet Murugesan Mohankumar
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-07
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INTERNATIONAL PATENT: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CHILDREN'S HOSPITAL RESEARCH CENTER AT OAKLAND, MARTIN, DAVID I.K., DEWITT, MARK, WALTERS, MARK C., MAGIS, WENDY J., THANGAVEL, SARAV...

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Advancing Precision Medicine: Recent Innovations in Gene Editing Technologies

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Endocytosis as a critical regulator of hematopoietic stem cell fate —implications for hematopoietic stem cell and gene therapy

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Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition

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Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin

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Homology-directed gene-editing approaches for hematopoietic stem and progenitor cell gene therapy

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Correlating the differences in the receptor binding domain of SARS-CoV-2 spike variants on their interactions with human ACE2 receptor

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The Strategies and Challenges of CCR5 Gene Editing in Hematopoietic Stem and Progenitor Cells for the Treatment of HIV

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Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications

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Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies

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Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication

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Direct Generation of Immortalized Erythroid Progenitor Cell Lines from Peripheral Blood Mononuclear Cells

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Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for [beta]-hemoglobinopathies

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Correlating the differences in the receptor binding domain of SARS-CoV-2 spike variants on their interactions with human ACE2 receptor

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Identification of novel HPFH-like mutations by CRISPR base editing that elevates the expression of fetal hemoglobin

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