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ArticlesPeer ReviewedFull Text
The global preclinical antibacterial pipeline
Author / Creator:Theuretzbacher, Ursula ; Outterson, Kevin ; Engel, Aleks ; Karlén, Anders
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Microbiology, 2020-05, Vol.18 (5), p.275-285
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Dual-mechanism antibiotics
Author / Creator:Theuretzbacher, Ursula
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2020-08, Vol.5 (8), p.984-985
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ArticlesPeer ReviewedFull Text
Critical analysis of antibacterial agents in clinical development
Author / Creator:Theuretzbacher, Ursula ; Bush, Karen ; Harbarth, Stephan ; Paul, Mical ; Rex, John H. ; Tacconelli, Evelina ; Thwaites, Guy E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Microbiology, 2020-05, Vol.18 (5), p.286-298
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ArticlesPeer ReviewedFull Text
The small-molecule antibiotics pipeline: 2014–2018
Author / Creator:Lepore, Cara ; Silver, Lynn ; Theuretzbacher, Ursula ; Thomas, Joe ; Visi, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2019-09, Vol.18 (10), p.739-739
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ArticlesPeer ReviewedFull Text
Pharmacokinetic/pharmacodynamic profile of voriconazole
Author / Creator:THEURETZBACHER, Ursula ; IHLE, Franziska ; DERENDORF, Hartmut
Publisher:Auckland: Adis international
Journal title:Clinical pharmacokinetics, 2006-01, Vol.45 (7), p.649-663
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Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions
Author / Creator:Roberts, Jason A, Prof ; Abdul-Aziz, Mohd H, BPharm ; Lipman, Jeffrey, Prof ; Mouton, Johan W, Prof ; Vinks, Alexander A, Prof ; Felton, Timothy W, Dr ; Hope, William W, Prof ; Farkas, Andras, Dr ; Neely, Michael N, MD ; Schentag, Jerome J, Dr ; Drusano, George, Prof ; Frey, Otto R, Dr ; Theuretzbacher, Ursula, Dr ; Kuti, Joseph L, Dr
Publisher:London: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2014-06, Vol.14 (6), p.498-509
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Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus
Author / Creator:Nation, Roger L, Prof ; Li, Jian, Prof ; Cars, Otto, Prof ; Couet, William, Prof ; Dudley, Michael N, Pharm D ; Kaye, Keith S, Prof ; Mouton, Johan W, Prof ; Paterson, David L, Prof ; Tam, Vincent H, Prof ; Theuretzbacher, Ursula, PhD ; Tsuji, Brian T, Pharm D ; Turnidge, John D, Prof
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2015-02, Vol.15 (2), p.225-234
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Integration of individual preclinical and clinical anti‐infective PKPD data to predict clinical study outcomes
Author / Creator:Aranzana‐Climent, Vincent ; van Os, Wisse ; Nutman, Amir ; Lellouche, Jonathan ; Dishon‐Benattar, Yael ; Rakovitsky, Nadya ; Daikos, George L. ; Skiada, Anna ; Pavleas, Ioannis ; Durante‐Mangoni, Emanuele ; Theuretzbacher, Ursula ; Paul, Mical ; Carmeli, Yehuda ; Friberg, Lena E.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2024-07, Vol.17 (7), p.e13870-n/a
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ArticlesPeer ReviewedFull Text
Excluded versus included patients in a randomized controlled trial of infections caused by carbapenem-resistant Gram-negative bacteria: relevance to external validity
Author / Creator:Daitch, Vered ; Paul, Mical ; Daikos, George L ; Durante-Mangoni, Emanuele ; Yahav, Dafna ; Carmeli, Yehuda ; Benattar, Yael Dishon ; Skiada, Anna ; Andini, Roberto ; Eliakim-Raz, Noa ; Nutman, Amir ; Zusman, Oren ; Antoniadou, Anastasia ; Cavezza, Giusi ; Adler, Amos ; Dickstein, Yaakov ; Pavleas, Ioannis ; Zampino, Rosa ; Bitterman, Roni ; Zayyad, Hiba ; Koppel, Fidi ; Zak-Doron, Yael ; Levi, Inbar ; Babich, Tanya ; Turjeman, Adi ; Ben-Zvi, Haim ; Friberg, Lena E ; Mouton, Johan W ; Theuretzbacher, Ursula ; Leibovici, Leonard
Publisher:England: BioMed Central Ltd
Journal title:BMC infectious diseases, 2021-03, Vol.21 (1), p.309-309, Article 309
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ArticlesPeer ReviewedFull Text
Linking Sustainable Use Policies to Novel Economic Incentives to Stimulate Antibiotic Research and Development
Author / Creator:Theuretzbacher, Ursula ; Årdal, Christine ; Harbarth, Stephan
Publisher:Basel: MDPI AG
Journal title:Infectious disease reports, 2017-03, Vol.9 (1), p.6836
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ArticlesPeer ReviewedFull Text
Insights into early stage of antibiotic development in small- and medium-sized enterprises: a survey of targets, costs, and durations
Author / Creator:Årdal, Christine ; Baraldi, Enrico ; Theuretzbacher, Ursula ; Outterson, Kevin ; Plahte, Jens ; Ciabuschi, Francesco ; Røttingen, John-Arne
Publisher:England: BioMed Central Ltd
Journal title:Journal of pharmaceutical policy and practice, 2018-04, Vol.11 (1), p.8-8, Article 8
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ArticlesPeer ReviewedFull Text
Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections...
Author / Creator:Dickstein, Yaakov ; Leibovici, Leonard ; Yahav, Dafna ; Eliakim-Raz, Noa ; Daikos, George L ; Skiada, Anna ; Antoniadou, Anastasia ; Carmeli, Yehuda ; Nutman, Amir ; Levi, Inbar ; Adler, Amos ; Durante-Mangoni, Emanuele ; Andini, Roberto ; Cavezza, Giusi ; Mouton, Johan W ; Wijma, Rixt A ; Theuretzbacher, Ursula ; Friberg, Lena E ; Kristoffersson, Anders N ; Zusman, Oren ; Koppel, Fidi ; Dishon Benattar, Yael ; Altunin, Sergey ; Paul, Mical
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2016-01, Vol.6 (4), p.e009956-e009956
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ArticlesPeer ReviewedFull Text
Antibacterial innovation in European SMEs
Author / Creator:Theuretzbacher, Ursula
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2016-12, Vol.15 (12), p.812-813
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ArticlesPeer ReviewedFull Text
Market watch: Antibacterial innovation in European SMEs
Author / Creator:Theuretzbacher, Ursula
Publisher:England: Nature Publishing Group
Journal title:Nature reviews. Drug discovery, 2016-12, Vol.15 (12), p.812-813
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ArticlesPeer ReviewedFull Text
Unrealized targets in the discovery of antibiotics for Gram-negative bacterial infections
Author / Creator:Theuretzbacher, Ursula ; Blasco, Benjamin ; Duffey, Maëlle ; Piddock, Laura J. V.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2023-12, Vol.22 (12), p.957-975
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ArticlesPeer ReviewedFull Text
Pharmacokinetic and Pharmacodynamic Issues for Antimicrobial Therapy in Patients With Cancer
Author / Creator:Theuretzbacher, Ursula
Publisher:Oxford: Oxford University Press
Journal title:Clinical infectious diseases, 2012-06, Vol.54 (12), p.1785-1792
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ArticlesPeer ReviewedFull Text
Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial
Author / Creator:Paul, Mical ; Daikos, George L ; Durante-Mangoni, Emanuele ; Yahav, Dafna ; Carmeli, Yehuda ; Benattar, Yael Dishon ; Skiada, Anna ; Andini, Roberto ; Eliakim-Raz, Noa ; Nutman, Amir ; Zusman, Oren ; Antoniadou, Anastasia ; Pafundi, Pia Clara ; Adler, Amos ; Dickstein, Yaakov ; Pavleas, Ioannis ; Zampino, Rosa ; Daitch, Vered ; Bitterman, Roni ; Zayyad, Hiba ; Koppel, Fidi ; Levi, Inbar ; Babich, Tanya ; Friberg, Lena E ; Mouton, Johan W ; Theuretzbacher, Ursula ; Leibovici, Leonard
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2018-04, Vol.18 (4), p.391-400
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Analysis of the clinical antibacterial and antituberculosis pipeline
Author / Creator:Theuretzbacher, Ursula ; Gottwalt, Simon ; Beyer, Peter ; Butler, Mark ; Czaplewski, Lloyd ; Lienhardt, Christian ; Moja, Lorenzo ; Paul, Mical ; Paulin, Sarah ; Rex, John H ; Silver, Lynn L ; Spigelman, Melvin ; Thwaites, Guy E ; Paccaud, Jean-Pierre ; Harbarth, Stephan
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2019-02, Vol.19 (2), p.e40-e50
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Piloting a framework for analysing the public contributions to R&D: new antibiotics in focus
Author / Creator:Schmidt, Louise ; Sehic, Ozren ; Theuretzbacher, Ursula ; Fabian, Daniel ; Wild, Claudia
Publisher:England: Taylor & Francis
Journal title:Journal of pharmaceutical policy and practice, 2025-12, Vol.18 (1), p.2449045
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ArticlesPeer ReviewedFull Text
β-lactam prolonged infusion: it's time to implement
Author / Creator:Paul, Mical ; Theuretzbacher, Ursula
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2018-01, Vol.18 (1), p.13-14
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The global preclinical antibacterial pipeline

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Dual-mechanism antibiotics

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Critical analysis of antibacterial agents in clinical development

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The small-molecule antibiotics pipeline: 2014–2018

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Pharmacokinetic/pharmacodynamic profile of voriconazole

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Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

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Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

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Integration of individual preclinical and clinical anti‐infective PKPD data to predict clinical study outcomes

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Excluded versus included patients in a randomized controlled trial of infections caused by carbapenem-resistant Gram-negative bacteria: relevance to external validity

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Linking Sustainable Use Policies to Novel Economic Incentives to Stimulate Antibiotic Research and Development

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Insights into early stage of antibiotic development in small- and medium-sized enterprises: a survey of targets, costs, and durations

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Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections...

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Antibacterial innovation in European SMEs

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Market watch: Antibacterial innovation in European SMEs

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Unrealized targets in the discovery of antibiotics for Gram-negative bacterial infections

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Pharmacokinetic and Pharmacodynamic Issues for Antimicrobial Therapy in Patients With Cancer

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Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial

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Analysis of the clinical antibacterial and antituberculosis pipeline

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Piloting a framework for analysing the public contributions to R&D: new antibiotics in focus

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β-lactam prolonged infusion: it's time to implement

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